Karin M Danzer

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi request reprint Seeding induced by alpha-synuclein oligomers provides evidence for spreading of alpha-synuclein pathology
    Karin M Danzer
    CNS Research Boehringer Ingelheim Pharma GmbH and Co KG, Biberach, Germany
    J Neurochem 111:192-203. 2009
  2. ncbi request reprint Functional protein kinase arrays reveal inhibition of p-21-activated kinase 4 by alpha-synuclein oligomers
    Karin M Danzer
    Boehringer Ingelheim Pharma GmbH and Co KG, Biberach, Germany
    J Neurochem 103:2401-7. 2007

Collaborators

Detail Information

Publications2

  1. doi request reprint Seeding induced by alpha-synuclein oligomers provides evidence for spreading of alpha-synuclein pathology
    Karin M Danzer
    CNS Research Boehringer Ingelheim Pharma GmbH and Co KG, Biberach, Germany
    J Neurochem 111:192-203. 2009
    ..Our data indicate that extracellular alpha-syn oligomers can induce intracellular alpha-syn aggregation, therefore we hypothesize that a similar mechanism might lead to alpha-syn pathology propagation...
  2. ncbi request reprint Functional protein kinase arrays reveal inhibition of p-21-activated kinase 4 by alpha-synuclein oligomers
    Karin M Danzer
    Boehringer Ingelheim Pharma GmbH and Co KG, Biberach, Germany
    J Neurochem 103:2401-7. 2007
    ..Thus, PAKs may represent a target for various neurotoxic protein oligomers, and signaling deficits may contribute to the behavioral defects in chronic neurodegenerative diseases...