Research Topics
Genomes and Genes | Soheil S DadrasSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Publications
Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodesSoheil S Dadras
Cutaneous Biology Research Center and Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA
Mod Pathol 18:1232-42. 2005..Assessment of lymphangiogenesis in primary melanomas may be a more effective approach than the currently used technique of measuring tumor thickness in selecting patients with early metastatic disease for aggressive therapy...
Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumorsVivien Schacht
Cutaneous Biology Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA
Am J Pathol 166:913-21. 2005....
Infantile hemangiomas are arrested in an early developmental vascular differentiation stateSoheil S Dadras
Cutaneous Biology Research Center and Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA
Mod Pathol 17:1068-79. 2004..The immature, incompletely differentiated immunophenotype of proliferating infantile hemangiomas may contribute to their rapid growth during the first few months of life...
Angiogenesis and lymphangiogenesis of skin cancersSoheil S Dadras
Cutaneous Biology Research Center and Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
Hematol Oncol Clin North Am 18:1059-70, viii. 2004..A better molecular understanding of the lymphatic system may provide new insights into the biology of tumor metastasis and may provide novel prognostic and therapeutic tools in metastatic disease...
Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survivalSoheil S Dadras
Cutaneous Biology Research Center and Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
Am J Pathol 162:1951-60. 2003..Our results reveal tumor lymphangiogenesis as a novel prognostic indicator for the risk of lymph node metastasis in cutaneous melanoma...
An N-terminal 80 kDa recombinant fragment of human thrombospondin-2 inhibits vascular endothelial growth factor induced endothelial cell migration in vitro and tumor growth and angiogenesis in vivoYun-Hee Noh
Cutaneous Biology Research Center and Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
J Invest Dermatol 121:1536-43. 2003..These findings identify TSP-2/NTF as a potent systemic inhibitor of tumor growth and angiogenesis, acting by direct inhibition of several endothelial cell functions involved in neovascularization...
Multifocal lymphangioendotheliomatosis with thrombocytopenia: a newly recognized clinicopathological entityPaula E North
Departments of Pathology and Otolaryngology, The University of Arkansas for Medical Sciences and Arkansas Children's Hospital, Little Rock, AR 72202, USA
Arch Dermatol 140:599-606. 2004..These congenital lesions, like tufted angioma and kaposiform hemangioendothelioma, show lymphatic differentiation, strengthening the association between abnormal lymphatic endothelium and coagulopathy...
Primary orbital melanoma associated with an occult episcleral nevusJohn T H Mandeville
Arch Ophthalmol 122:287-90. 2004
Inflammatory manifestations of experimental lymphatic insufficiencyRaymond Tabibiazar
Stanford Center for Lymphatic and Venous Disorders, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, United States of America
PLoS Med 3:e254. 2006..Further study of genes identified through this effort will continue to elucidate the molecular mechanisms and lead to potential therapeutic strategies for lymphatic vascular insufficiency...
F-18 FDG PET/CT imaging of a subcutaneous scalp metastasis from primary carcinoma of the thyroidRyan D Niederkohr
Division of Nuclear Medicine, Stanford University Medical Center, Stanford University Hospital and Clinics, Stanford, CA 94305-5281, USA
Clin Nucl Med 32:162-4. 2007
Lymphatic vascular invasion in ovarian serous tumors of low malignant potential with stromal microinvasion: a case control studyAnkur R Sangoi
Department of Pathology, Stanford University, Stanford, CA 94305, USA
Am J Surg Pathol 32:261-8. 2008..The presence of LVI in microinvasive S-LMP corroborates the view that microinvasion represents an early, but very low risk, invasive process that morphologically links S-LMP and low-grade serous carcinoma...
Diagnostic implications of podoplanin expression in peripheral nerve sheath neoplasmsChris H Jokinen
Department of Pathology, University of Washington, Seattle, USA
Am J Clin Pathol 129:886-93. 2008..These results suggest diffuse podoplanin expression or coexpression of podoplanin and S-100 is limited to schwannoma and EMPNST and may be useful in the evaluation of these neoplasms...
