Cristina Cusin

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi request reprint A randomized, double-blind, placebo-controlled trial of pramipexole augmentation in treatment-resistant major depressive disorder
    Cristina Cusin
    Depression Clinical and Research Program, Massachusetts General Hospital, One Bowdoin Square, Ste 630, Boston, MA 02114
    J Clin Psychiatry 74:e636-41. 2013
  2. pmc Somatic therapies for treatment-resistant depression: ECT, TMS, VNS, DBS
    Cristina Cusin
    Division of Neurotherapeutics, Department of Psychiatry, Massachusetts General Hospital, 149 13th Street, Rm 2612, Charlestown, MA 02129, USA
    Biol Mood Anxiety Disord 2:14. 2012
  3. ncbi request reprint Early symptomatic worsening during treatment with fluoxetine in major depressive disorder: prevalence and implications
    Cristina Cusin
    Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 68:52-7. 2007
  4. ncbi request reprint Treatment-associated suicidal ideation and adverse effects in an open, multicenter trial of fluoxetine for major depressive episodes
    Roy H Perlis
    Depression Clinical and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Psychother Psychosom 76:40-6. 2007
  5. ncbi request reprint Clinical and genetic dissection of anger expression and CREB1 polymorphisms in major depressive disorder
    Roy H Perlis
    Depression Clinical and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Biol Psychiatry 62:536-40. 2007
  6. ncbi request reprint Antidepressant response and well-being in pre-, peri- and postmenopausal women with major depressive disorder treated with fluoxetine
    Paolo Cassano
    The Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychother Psychosom 74:362-5. 2005
  7. ncbi request reprint Pooling pharmacogenetic studies on the serotonin transporter: a mega-analysis
    Alessandro Serretti
    Department of Psychiatry, Vita Salute University, Fondazione Centro San Raffaele del Monte Tabor, Milan, Italy
    Psychiatry Res 145:61-5. 2006
  8. ncbi request reprint Clinical and demographic features of mood disorder subtypes
    Alessandro Serretti
    Department of Psychiatry, Vita Salute University, San Raffaele Institute, Via Luigi Prinetti 29, Milan, Italy
    Psychiatry Res 112:195-210. 2002
  9. ncbi request reprint Influence of monoamine oxidase A and serotonin receptor 2A polymorphisms in SSRI antidepressant activity
    Cristina Cusin
    Department of Psychiatry, Vita Salute University, Raffaele del Monte Tabor, Milan, Italy
    Int J Neuropsychopharmacol 5:27-35. 2002
  10. ncbi request reprint Insomnia improvement during antidepressant treatment and CLOCK gene polymorphism
    Alessandro Serretti
    Department of Neuropsychiatric Sciences, Istituto Scientifico, Universitario Ospedale San Raffaele, University of Milan School of Medicine, Via Luigi Prinetti 29, 20127 Milan, Italy
    Am J Med Genet B Neuropsychiatr Genet 137:36-9. 2005

Detail Information

Publications14

  1. doi request reprint A randomized, double-blind, placebo-controlled trial of pramipexole augmentation in treatment-resistant major depressive disorder
    Cristina Cusin
    Depression Clinical and Research Program, Massachusetts General Hospital, One Bowdoin Square, Ste 630, Boston, MA 02114
    J Clin Psychiatry 74:e636-41. 2013
    ..Existing augmentation or combination strategies can have substantial safety concerns that may limit their application...
  2. pmc Somatic therapies for treatment-resistant depression: ECT, TMS, VNS, DBS
    Cristina Cusin
    Division of Neurotherapeutics, Department of Psychiatry, Massachusetts General Hospital, 149 13th Street, Rm 2612, Charlestown, MA 02129, USA
    Biol Mood Anxiety Disord 2:14. 2012
    ..VNS has been FDA-approved for TRD, however it is not indicated for management of acute illness. DBS for TRD is still an experimental area of investigation and double-blind clinical trials are underway...
  3. ncbi request reprint Early symptomatic worsening during treatment with fluoxetine in major depressive disorder: prevalence and implications
    Cristina Cusin
    Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 68:52-7. 2007
    ..While patterns of response have been examined as possible predictors of outcome, the clinical correlates and implications of early worsening per se have not been investigated...
  4. ncbi request reprint Treatment-associated suicidal ideation and adverse effects in an open, multicenter trial of fluoxetine for major depressive episodes
    Roy H Perlis
    Depression Clinical and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Psychother Psychosom 76:40-6. 2007
    ..The time course and clinical correlates of this phenomenon have not been characterized in detail...
  5. ncbi request reprint Clinical and genetic dissection of anger expression and CREB1 polymorphisms in major depressive disorder
    Roy H Perlis
    Depression Clinical and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Biol Psychiatry 62:536-40. 2007
    ..Therefore, we examined the association between CREB1 polymorphisms and anger expression in MDD...
  6. ncbi request reprint Antidepressant response and well-being in pre-, peri- and postmenopausal women with major depressive disorder treated with fluoxetine
    Paolo Cassano
    The Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychother Psychosom 74:362-5. 2005
    ..We assessed the impact of menopausal status on treatment response and well-being in a cohort of outpatient women with major depressive disorder (DSM-III-R criteria), who received treatment with fluoxetine (20 mg/day for 8 weeks)...
  7. ncbi request reprint Pooling pharmacogenetic studies on the serotonin transporter: a mega-analysis
    Alessandro Serretti
    Department of Psychiatry, Vita Salute University, Fondazione Centro San Raffaele del Monte Tabor, Milan, Italy
    Psychiatry Res 145:61-5. 2006
    ..This result supports the involvement of the SERTPR gene in response to antidepressant treatments...
  8. ncbi request reprint Clinical and demographic features of mood disorder subtypes
    Alessandro Serretti
    Department of Psychiatry, Vita Salute University, San Raffaele Institute, Via Luigi Prinetti 29, Milan, Italy
    Psychiatry Res 112:195-210. 2002
    ..This finding may help in the search for the biological basis of mood disorders...
  9. ncbi request reprint Influence of monoamine oxidase A and serotonin receptor 2A polymorphisms in SSRI antidepressant activity
    Cristina Cusin
    Department of Psychiatry, Vita Salute University, Raffaele del Monte Tabor, Milan, Italy
    Int J Neuropsychopharmacol 5:27-35. 2002
    ..The investigated MAOA and 5-HT-2A gene variants, therefore, do not seem to play a major role in SSRI antidepressant activity...
  10. ncbi request reprint Insomnia improvement during antidepressant treatment and CLOCK gene polymorphism
    Alessandro Serretti
    Department of Neuropsychiatric Sciences, Istituto Scientifico, Universitario Ospedale San Raffaele, University of Milan School of Medicine, Via Luigi Prinetti 29, 20127 Milan, Italy
    Am J Med Genet B Neuropsychiatr Genet 137:36-9. 2005
    ..This, together with previous findings on this polymorphism could lead to a further dissection of the complexity of mood disorders...
  11. ncbi request reprint Further evidence of a combined effect of SERTPR and TPH on SSRIs response in mood disorders
    Alessandro Serretti
    Department of Psychiatry, Vita Salute University, San Raffaele Institute, Milan, Italy
    Am J Med Genet B Neuropsychiatr Genet 129:36-40. 2004
    ..Thus, the previous positive association was not fully replicated for TPH. The present independent replication confirms SERTPR variants as a liability factor for antidepressant efficacy while the TPH effect is not unequivocal...
  12. ncbi request reprint Comparison of response to fluvoxamine in nondemented elderly compared to younger patients affected by major depression
    Raffaella Zanardi
    Department of Psychiatry San Raffaele Institute, Vita Salute University, Via Stamira d Ancona 20, 20127 Milan, Italy
    J Clin Psychopharmacol 23:535-9. 2003
    ..0006). This difference between the 2 age groups was evident since the 2nd week of treatment, and it appeared to be independent of other clinical variables...
  13. ncbi request reprint SSRIs antidepressant activity is influenced by G beta 3 variants
    Alessandro Serretti
    Department of Psychiatry, Vita Salute University, Fondazione Centro San Raffaele del Monte Tabor, Milan, Italy
    Eur Neuropsychopharmacol 13:117-22. 2003
    ..009) and this effect was independent from analyzed demographic and clinical variables. These results confirm preliminary reports and shed further light on the genetics of the response to antidepressant treatments...
  14. ncbi request reprint Seasonal variations of lithium plasma levels
    Cristina Cusin
    Department of Psychiatry, Vita Salute University, Fondazione Centro San Raffaele del Monte Tabor, Via Stamira d Ancona 20, 20127, Milan, Italy
    Psychiatry Res 111:35-41. 2002
    ..In conclusion, we observed a significant variation of lithium plasma levels according to seasons. If confirmed, this finding could have both clinical and research implications...