G C Curhan

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Genetic polymorphisms and the risk of accelerated renal function decline in women
    Cynthia Cooper Worobey
    Renal Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 4:e4787. 2009
  2. pmc Genetic polymorphisms of angiotensin-2 type 1 receptor and angiotensinogen and risk of renal dysfunction and coronary heart disease in type 2 diabetes mellitus
    Julie Lin
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    BMC Nephrol 10:9. 2009
  3. pmc NPHS2 variation in focal and segmental glomerulosclerosis
    Stephen J Tonna
    Renal Division, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    BMC Nephrol 9:13. 2008
  4. ncbi request reprint A 44-year-old woman with kidney stones
    Gary C Curhan
    Harvard Medical School and Harvard School of Public Health, Boston, Mass, USA
    JAMA 293:1107-14. 2005
  5. ncbi request reprint 24-h uric acid excretion and the risk of kidney stones
    G C Curhan
    Department of Medicine, Renal Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Kidney Int 73:489-96. 2008
  6. doi request reprint Sugar-sweetened beverages and chronic disease
    Gary C Curhan
    Channing Laboratory and Renal Division, Department of Medicine, Boston, Massachusetts 02115, USA
    Kidney Int 77:569-70. 2010
  7. ncbi request reprint Birth weight and adult hypertension, diabetes mellitus, and obesity in US men
    G C Curhan
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 94:3246-50. 1996
  8. ncbi request reprint Birth weight and adult hypertension and obesity in women
    G C Curhan
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 94:1310-5. 1996
  9. ncbi request reprint Nonnarcotic analgesic use and the risk of hypertension in US women
    Julien Dedier
    Section of General Internal Medicine Research Unit, Department of Medicine, Boston Medical Center, Mass, USA
    Hypertension 40:604-8; discussion 601-3. 2002
  10. pmc A prospective study of vitamin intake and the risk of hearing loss in men
    Josef Shargorodsky
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, 181 Longwood Ave, Boston, MA 02115, USA
    Otolaryngol Head Neck Surg 142:231-6. 2010

Research Grants

Collaborators

Detail Information

Publications103 found, 100 shown here

  1. pmc Genetic polymorphisms and the risk of accelerated renal function decline in women
    Cynthia Cooper Worobey
    Renal Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 4:e4787. 2009
    ..Reduced glomerular filtration rate is an important predictor of cardiovascular disease and death. Genetic polymorphisms, particularly in genes involved in the renin-angiotensin system (RAS), may influence the rate of renal function decline...
  2. pmc Genetic polymorphisms of angiotensin-2 type 1 receptor and angiotensinogen and risk of renal dysfunction and coronary heart disease in type 2 diabetes mellitus
    Julie Lin
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    BMC Nephrol 10:9. 2009
    ....
  3. pmc NPHS2 variation in focal and segmental glomerulosclerosis
    Stephen J Tonna
    Renal Division, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    BMC Nephrol 9:13. 2008
    ..Homozygous or compound heterozygous mutations in the podocin gene NPHS2 are found in 10-30% of pediatric cases of steroid resistant nephrosis and/or FSGS...
  4. ncbi request reprint A 44-year-old woman with kidney stones
    Gary C Curhan
    Harvard Medical School and Harvard School of Public Health, Boston, Mass, USA
    JAMA 293:1107-14. 2005
  5. ncbi request reprint 24-h uric acid excretion and the risk of kidney stones
    G C Curhan
    Department of Medicine, Renal Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Kidney Int 73:489-96. 2008
    ..In addition, the current definitions of normal levels for urinary factors need to be re-evaluated...
  6. doi request reprint Sugar-sweetened beverages and chronic disease
    Gary C Curhan
    Channing Laboratory and Renal Division, Department of Medicine, Boston, Massachusetts 02115, USA
    Kidney Int 77:569-70. 2010
    ..Nevertheless, given their demonstrated adverse health associations and the lack of any health benefit, the evidence favors minimization of sugar-sweetened beverage intake...
  7. ncbi request reprint Birth weight and adult hypertension, diabetes mellitus, and obesity in US men
    G C Curhan
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 94:3246-50. 1996
    ..Further study of these diseases in a large cohort with information on a wide variety of risk factors is essential to determine more precisely the risks associated with birth weight...
  8. ncbi request reprint Birth weight and adult hypertension and obesity in women
    G C Curhan
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 94:1310-5. 1996
    ..Low birth weight has been associated with an increased risk of hypertension, and high birth weight has been associated with increased adult body mass index. Published studies on adults have included only a small number of women...
  9. ncbi request reprint Nonnarcotic analgesic use and the risk of hypertension in US women
    Julien Dedier
    Section of General Internal Medicine Research Unit, Department of Medicine, Boston Medical Center, Mass, USA
    Hypertension 40:604-8; discussion 601-3. 2002
    ....
  10. pmc A prospective study of vitamin intake and the risk of hearing loss in men
    Josef Shargorodsky
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, 181 Longwood Ave, Boston, MA 02115, USA
    Otolaryngol Head Neck Surg 142:231-6. 2010
    ..Hearing loss is the most common sensory disorder in the United States, afflicting more than 36 million people. Higher intakes of vitamins C, E, beta carotene, B12, and folate have been proposed to reduce the risk of hearing loss...
  11. pmc Lipid and inflammatory biomarkers and kidney function decline in type 2 diabetes
    J Lin
    Renal Division, MRB 4, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Diabetologia 53:263-7. 2010
    ..Potentially modifiable biomarkers may influence the decline in estimated GFR (eGFR), but few data are currently available in type 2 diabetic adults...
  12. ncbi request reprint Type 2 diabetes mellitus and risk of developing urinary incontinence
    Karen L Lifford
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Am Geriatr Soc 53:1851-7. 2005
    ..To evaluate the association between type 2 diabetes mellitus (DM) and development of urinary incontinence in women...
  13. ncbi request reprint Cholesterol and the risk of renal dysfunction in apparently healthy men
    Elke S Schaeffner
    Divisions of Preventive Medicine, and Aging, and Cardiovascular Disease, and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, USA
    J Am Soc Nephrol 14:2084-91. 2003
    ..5 mg/dl...
  14. ncbi request reprint Postmenopausal hormone therapy and risk of developing urinary incontinence
    Francine Grodstein
    Channing Laboratory and Renal Division, Department of Medicine, Brigham and Women s Hospital, 181 Longwood Avenue, Boston, MA 02115, USA
    Obstet Gynecol 103:254-60. 2004
    ..To better understand associations between post-menopausal hormone therapy and the development of urinary incontinence...
  15. ncbi request reprint Twenty-four-hour urine chemistries and the risk of kidney stones among women and men
    G C Curhan
    Channing Laboratory, Department of Medicine, Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Kidney Int 59:2290-8. 2001
    ..Unfortunately, the majority of previous studies of 24-hour urine chemistries were limited by the inclusion of recurrent stone formers and poorly defined controls...
  16. ncbi request reprint Intake of vitamins B6 and C and the risk of kidney stones in women
    G C Curhan
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Nephrol 10:840-5. 1999
    ..06 (95% confidence interval, 0.69 to 1.64). Large doses of vitamin B6 may reduce the risk of kidney stone formation in women. Routine restriction of vitamin C to prevent stone formation appears unwarranted...
  17. ncbi request reprint Factors influencing serum cystatin C levels other than renal function and the impact on renal function measurement
    Eric L Knight
    Channing Laboratory, Renal Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Kidney Int 65:1416-21. 2004
    ....
  18. pmc Psoriasis and the risk of diabetes and hypertension: a prospective study of US female nurses
    Abrar A Qureshi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, 45 Francis St, 221L, Boston, MA 02115, USA
    Arch Dermatol 145:379-82. 2009
    ..To evaluate the independent association between psoriasis and risk of diabetes and hypertension...
  19. ncbi request reprint Kidney dysfunction, inflammation, and coronary events: a prospective study
    Eric L Knight
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Nephrol 15:1897-903. 2004
    ..These findings warrant further investigation in other populations...
  20. pmc Oral contraceptive use and incident urinary incontinence in premenopausal women
    Mary K Townsend
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    J Urol 181:2170-5. 2009
    ..We investigated the association between oral contraceptive pills and incident urinary incontinence in premenopausal women enrolled in the Nurses' Health Study II...
  21. ncbi request reprint Fluid intake and the risk of bladder cancer in men
    D S Michaud
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 340:1390-7. 1999
    ..The data on fluid intake in relation to the risk of bladder cancer are inconclusive...
  22. ncbi request reprint Body mass index, weight gain, and incident urinary incontinence in middle-aged women
    Mary K Townsend
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Obstet Gynecol 110:346-53. 2007
    ..To describe the relations between body mass index (BMI; kg/m(2)), weight gain, and incident urinary incontinence in middle-aged women...
  23. pmc Diet-dependent net acid load and risk of incident hypertension in United States women
    Luxia Zhang
    Channing Laboratory Renal Division, Brigham and Women s Hospital, 181 Longwood Ave, Boston, MA 02115, USA
    Hypertension 54:751-5. 2009
    ..In conclusion, a high diet-dependent net acid load is independently associated with a higher risk of incident hypertension...
  24. doi request reprint BMI, waist circumference, and incident urinary incontinence in older women
    Mary K Townsend
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Obesity (Silver Spring) 16:881-6. 2008
    ..77). Waist circumference was associated only with stress UI (P for trend <0.001). These results suggest that women who avoid high BMI and waist circumference may have a lower risk of UI development...
  25. pmc A prospective study of cardiovascular risk factors and incident hearing loss in men
    Josef Shargorodsky
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Laryngoscope 120:1887-91. 2010
    ..Cardiovascular risk factors have been associated with the risk of hearing loss in cross-sectional studies, but prospective data are currently lacking...
  26. ncbi request reprint A prospective study of body mass index, hypertension, and smoking and the risk of renal cell carcinoma (United States)
    Keith T Flaherty
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Causes Control 16:1099-106. 2005
    ..We prospectively investigated the independent association of hypertension, thiazide use, body mass index, weight change, and smoking with the risk of renal cell carcinoma among men and women using biennial mailed questionnaires...
  27. pmc Risk factors for urinary incontinence among middle-aged women
    Kim N Danforth
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Obstet Gynecol 194:339-45. 2006
    ..The purpose of this study was to identify risk factors for urinary incontinence in middle-aged women...
  28. ncbi request reprint Lifetime nonnarcotic analgesic use and decline in renal function in women
    Gary C Curhan
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 164:1519-24. 2004
    ..However, limited prospective information is available on the long-term effects of aspirin, other nonsteroidal anti-inflammatory drugs (NSAIDs), and acetaminophen on renal function...
  29. ncbi request reprint Frequency of analgesic use and risk of hypertension in younger women
    Gary C Curhan
    Channing Laboratory, Brigham and Women s Hospital, 181 Longwood Ave, Boston, MA 02115, USA
    Arch Intern Med 162:2204-8. 2002
    ..However, little prospective information is available on the association between analgesic use and the risk of hypertension...
  30. ncbi request reprint Total fluid intake and use of individual beverages and risk of renal cell cancer in two large cohorts
    Jung Eun Lee
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 15:1204-11. 2006
    ..Our data suggest an inverse association between alcohol intake and risk of renal cell cancer, but do not support the hypothesis that greater total fluid intake reduces the risk of renal cell cancer...
  31. pmc CRP gene variation and risk of community-acquired pneumonia
    Kenneth J Mukamal
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Respirology 15:160-4. 2010
    ..Whether this variation influences risk of infection, and hence whether CRP has anti-infective activity in humans, is uncertain...
  32. pmc The incidence of urinary incontinence across Asian, black, and white women in the United States
    Mary K Townsend
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Obstet Gynecol 202:378.e1-7. 2010
    ..We calculated incidence rates of urinary incontinence by incontinence frequency and type over 4 years in Asian, black, and white women in the United States...
  33. ncbi request reprint Prospective study of acetaminophen use and newly diagnosed asthma among women
    R Graham Barr
    Division of General Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Am J Respir Crit Care Med 169:836-41. 2004
    ....
  34. pmc Vitamin and micronutrient intake and the risk of community-acquired pneumonia in US women
    Mark I Neuman
    Division of Emergency Medicine, Children s Hospital, Boston, Mass 02115, USA
    Am J Med 120:330-6. 2007
    ..There are limited data regarding the role of dietary and supplemental vitamin intake and the risk of community-acquired pneumonia...
  35. ncbi request reprint Inflammatory markers and the risk of coronary heart disease in men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 351:2599-610. 2004
    ..The value of these inflammatory markers as independent predictors remains controversial...
  36. pmc Psoriasis and risk of nonfatal cardiovascular disease in U.S. women: a cohort study
    W Q Li
    Department of Dermatology, Harvard Medical School, Boston, MA 02115, USA
    Br J Dermatol 166:811-8. 2012
    ..Psoriasis has been linked to cardiovascular comorbidities in cross-sectional studies, but evidence regarding the association between psoriasis and incident cardiovascular disease (CVD) is limited...
  37. ncbi request reprint Fructose consumption and the risk of kidney stones
    E N Taylor
    Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Kidney Int 73:207-12. 2008
    ..Non-fructose carbohydrates were not associated with increased risk in any cohort. Our study suggests that fructose intake is independently associated with an increased risk of incident kidney stones...
  38. ncbi request reprint Body size and 24-hour urine composition
    Eric N Taylor
    Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Kidney Dis 48:905-15. 2006
    ..Greater body mass index (BMI) is a risk factor for kidney stones. However, the relation between BMI and the urinary excretion of many lithogenic factors remains unclear...
  39. doi request reprint Change in prevalence of hearing loss in US adolescents
    Josef Shargorodsky
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    JAMA 304:772-8. 2010
    ..Hearing loss is common and, in young persons, can compromise social development, communication skills, and educational achievement...
  40. pmc Post-menopausal hormone use and albuminuria
    Emily L Schopick
    Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Nephrol Dial Transplant 24:3739-44. 2009
    ..Post-menopausal hormone use may influence the renin-angiotensin system and renal endothelial function, impacting albumin excretion. The association between post-menopausal hormone use and albuminuria is not well defined...
  41. pmc Plasma prolactin level and risk of incident hypertension in postmenopausal women
    Luxia Zhang
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Hypertens 28:1400-5. 2010
    ..Laboratory and cross-sectional human studies suggest a potential role for prolactin in the pathogenesis of hypertension; however, the prospective association between prolactin and hypertension has not been previously reported...
  42. ncbi request reprint Mild renal insufficiency and risk of congestive heart failure in men and women > or =70 years of age
    Claudia U Chae
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215 1204, USA
    Am J Cardiol 92:682-6. 2003
    ..43, 95% CI 1.17 to 1.74). Thus, mild renal insufficiency was a strong independent predictor of CHF in this cohort, suggesting that serum creatinine may offer a readily accessible tool to identify elderly patients at risk for CHF...
  43. pmc Associations of diet with albuminuria and kidney function decline
    Julie Lin
    Renal Division, Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Clin J Am Soc Nephrol 5:836-43. 2010
    ..Sparse longitudinal data exist on how diet influences microalbuminuria and estimated GFR (eGFR) decline in people with well-preserved kidney function...
  44. ncbi request reprint Plasma 25-hydroxyvitamin D levels and risk of incident hypertension
    John P Forman
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Hypertension 49:1063-9. 2007
    ..31 (95% CI: 2.03 to 2.63) in men and 1.57 (95% CI: 1.44 to 1.72) in women. Plasma 25(OH)D levels are inversely associated with risk of incident hypertension...
  45. ncbi request reprint Prevalence of painful bladder syndrome in older women
    Karen L Lifford
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Urology 73:494-8. 2009
    ..To examine the prevalence of and symptoms associated with painful bladder syndrome (PBS) in a population of older women, utilizing the Nurses' Health Study (NHS) cohort...
  46. ncbi request reprint Habitual caffeine intake and the risk of hypertension in women
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    JAMA 294:2330-5. 2005
    ..Caffeine acutely increases blood pressure, but the association between habitual consumption of caffeinated beverages and incident hypertension is uncertain...
  47. pmc Prospective study of alcohol use and hearing loss in men
    Sharon G Curhan
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Ear Hear 32:46-52. 2011
    ..The purpose of this study was to prospectively examine the relation between alcohol use and hearing loss in men...
  48. ncbi request reprint Cardiovascular risk factors in women with and without rheumatoid arthritis
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Boston, MA 02120, USA
    Arthritis Rheum 50:3444-9. 2004
    ..The risk of cardiovascular disease (CVD) is increased in patients with rheumatoid arthritis (RA). The objective of this study was to examine the distribution of known CVD risk factors and biomarkers of CVD in women with and without RA...
  49. ncbi request reprint The impact of protein intake on renal function decline in women with normal renal function or mild renal insufficiency
    Eric L Knight
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Ann Intern Med 138:460-7. 2003
    ..However, the long-term impact of protein intake on renal function in persons with normal renal function or mild renal insufficiency is unknown...
  50. pmc Choice of vascular access among incident hemodialysis patients: a decision and cost-utility analysis
    Hui Xue
    Renal Division, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Clin J Am Soc Nephrol 5:2289-96. 2010
    ..This study compares survival, quality-adjusted survival, and costs among incident hemodialysis patients after attempted placement of AVFs or arteriovenous grafts (AVGs)...
  51. pmc DASH-style diet and 24-hour urine composition
    Eric N Taylor
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Clin J Am Soc Nephrol 5:2315-22. 2010
    ..This study examined associations between a DASH-style diet and 24-hour excretions of urinary lithogenic factors...
  52. pmc DASH-style diet associates with reduced risk for kidney stones
    Eric N Taylor
    Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Nephrol 20:2253-9. 2009
    ..Exclusion of participants with hypertension did not change the results. In conclusion, consumption of a DASH-style diet is associated with a marked decrease in kidney stone risk...
  53. ncbi request reprint The association between mental health, physical function, and hemodialysis mortality
    Eric L Knight
    Renal Unit, General Medicine Unit, Harvard Medical School, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02115, USA
    Kidney Int 63:1843-51. 2003
    ..One such approach is to stratify individuals by self-reported mental health and physical function. Examining these parameters at baseline, and over time, may help identify individuals at greater risk for mortality...
  54. pmc Menopause, postmenopausal hormone use and risk of incident gout
    A Elisabeth Hak
    Section of Rheumatology and the Clinical Epidemiology Unit, Boston University of School of Medicine, 650 Albany Street, Suite 200, Boston, MA 02118, USA
    Ann Rheum Dis 69:1305-9. 2010
    ..To prospectively study the relation between menopause, postmenopausal hormone use and risk of gout, since female sex hormones have been postulated to decrease gout risk among women...
  55. pmc Uric acid and insulin sensitivity and risk of incident hypertension
    John P Forman
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 169:155-62. 2009
    ..Corresponding circulating biomarkers are associated with risk of hypertension, but because these factors may be interrelated, whether they independently affect risk is unknown...
  56. ncbi request reprint Moderate alcohol intake and renal function decline in women: a prospective study
    Eric L Knight
    The Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Nephrol Dial Transplant 18:1549-54. 2003
    ..Experimentally, alcohol may adversely affect renal function, but clinical data are limited and no large, prospective studies have examined this issue...
  57. pmc Race and mortality after acute renal failure
    Sushrut S Waikar
    Department of Medicine, Brigham and Women s Hospital, MRB 4, 75 Francis Street, Boston, MA 02115, USA
    J Am Soc Nephrol 18:2740-8. 2007
    ..In conclusion, in-hospital mortality is lower for black patients with acute renal failure than white patients. Future studies should assess the reasons for this difference...
  58. ncbi request reprint Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis
    Daniel H Solomon
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    Circulation 107:1303-7. 2003
    ..Rheumatoid arthritis may be associated with an increased risk of cardiovascular disease. We compared the incidence rates of myocardial infarction and stroke in subjects with and without rheumatoid arthritis...
  59. ncbi request reprint Folate intake and the risk of incident hypertension among US women
    John P Forman
    Renal Division, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass, USA
    JAMA 293:320-9. 2005
    ..Folate has important beneficial effects on endothelial function, but there is limited information about folate intake and risk of incident hypertension...
  60. ncbi request reprint Prospective study of moderate alcohol consumption and risk of hypertension in young women
    Ravi Thadhani
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, 181 Longwood Ave, Boston, MA 02115, USA
    Arch Intern Med 162:569-74. 2002
    ..However, the effect of moderate alcohol consumption; the specific effects of wine, beer, and liquor; and the pattern of drinking in relation to risk of hypertension among young women are unclear...
  61. ncbi request reprint Obesity, weight gain, and the risk of kidney stones
    Eric N Taylor
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    JAMA 293:455-62. 2005
    ..It is unclear if obesity increases the risk of stone formation, and it is not known if weight gain influences risk...
  62. ncbi request reprint Dietary factors and the risk of incident kidney stones in men: new insights after 14 years of follow-up
    Eric N Taylor
    Department of Medicine, Channing Laboratory, Third Floor, Brigham and Women s Hospital, 181 Longwood Avenue, Boston, MA 02115, USA
    J Am Soc Nephrol 15:3225-32. 2004
    ..Because age and body size affect the relation between diet and kidney stones, dietary recommendations for stone prevention should be tailored to the individual patient...
  63. ncbi request reprint Diabetes mellitus and the risk of nephrolithiasis
    Eric N Taylor
    Channing Laboratory, and Renal Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Kidney Int 68:1230-5. 2005
    ..Existing cross-sectional data on the association between DM and nephrolithiasis are limited, and no prospective study to date has evaluated the relation between DM and the risk of kidney stones...
  64. pmc Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer
    Andrew T Chan
    Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    JAMA 294:914-23. 2005
    ..However, data on long-term risk of colorectal cancer according to dose, timing, or duration of therapy with aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) remain limited...
  65. ncbi request reprint Vitamin D intake and risk of incident hypertension: results from three large prospective cohort studies
    John P Forman
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Hypertension 46:676-82. 2005
    ..We conclude that higher intake of vitamin D is not associated with a lower risk of incident hypertension...
  66. pmc Plasma 25-hydroxyvitamin D levels and risk of incident hypertension among young women
    John P Forman
    Department of Medicine, Renal Division and Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachussetts, USA
    Hypertension 52:828-32. 2008
    ..7% of the study population) had a multivariable odds ratio of 1.47 (95% CI: 1.10 to 1.97). Plasma 25(OH)D levels are inversely and independently associated with the risk of developing hypertension...
  67. pmc Determinants of 24-hour urinary oxalate excretion
    Eric N Taylor
    Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Clin J Am Soc Nephrol 3:1453-60. 2008
    ..However, the determinants of urinary oxalate excretion are unclear. The objective was to examine the impact of dietary factors, age, body size, diabetes, and urinary factors on 24-h urinary oxalate...
  68. ncbi request reprint Cardiovascular care and cancer screening in female nurses with and without rheumatoid arthritis
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Arthritis Rheum 51:429-32. 2004
    ..To compare frequencies of cancer screening and cardiovascular treatments aimed at reducing acute myocardial infarction in women with and without rheumatoid arthritis (RA)...
  69. pmc Analgesic use and the risk of hearing loss in men
    Sharon G Curhan
    Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Med 123:231-7. 2010
    ..Hearing loss is a common sensory disorder, yet prospective data on potentially modifiable risk factors are limited. Regularly used analgesics, the most commonly used drugs in the US, may be ototoxic and contribute to hearing loss...
  70. pmc Physical activity and albuminuria
    Emily S Robinson
    Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women sHospital, and Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Epidemiol 171:515-21. 2010
    ..61 (95% CI: 0.37, 0.99), and for those in the highest quintile of walking compared with the lowest quintile, it was 0.69 (95% CI: 0.47, 1.02). Greater physical activity is associated with a lower ACR in nondiabetic women...
  71. ncbi request reprint Antihypertensive medications and the risk of incident type 2 diabetes
    Eric N Taylor
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    Diabetes Care 29:1065-70. 2006
    ..The purpose of this study was to examine the association between the use of different classes of antihypertensive medications and the risk of incident type 2 diabetes...
  72. ncbi request reprint Frequency of analgesic use and risk of hypertension among men
    John P Forman
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 167:394-9. 2007
    ..To our knowledge, the association between the use of these analgesics, particularly acetaminophen, and the risk of hypertension among men has not been extensively studied...
  73. ncbi request reprint Nephrolithiasis and risk of hypertension
    F Madore
    Renal Division, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
    Am J Hypertens 11:46-53. 1998
    ..99, 95% CI: 0.82 to 1.21). These data support the hypothesis that prior occurrence of nephrolithiasis increases the risk of subsequent hypertension...
  74. ncbi request reprint Epidemiologic evidence for the role of oxalate in idiopathic nephrolithiasis
    G C Curhan
    Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02114, USA
    J Endourol 13:629-31. 1999
    ..More valid and comprehensive information on the oxalate content of food are desperately needed. Because the data on dietary oxalate are inconclusive, the routine restriction of dietary oxalate needs to be reexamined...
  75. ncbi request reprint High body mass index and hypercholesterolemia: risk of hypertensive disorders of pregnancy
    R Thadhani
    Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Obstet Gynecol 94:543-50. 1999
    ..To examine the relationship between pregravid body mass index (BMI), elevated cholesterol level, and the development of hypertensive disorders of pregnancy...
  76. ncbi request reprint Diet and fluid prescription in stone disease
    E N Taylor
    Renal Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Kidney Int 70:835-9. 2006
    ..Adequate fluid intake and appropriate dietary modifications may substantially reduce the morbidity and costs associated with recurrent nephrolithiasis...
  77. ncbi request reprint A prospective study of age and lifestyle factors in relation to community-acquired pneumonia in US men and women
    I Baik
    Harvard School of Public Health, Department of Nutrition, 665 Huntington Ave, Bldg 2, Room 329, Boston, MA 02115, USA
    Arch Intern Med 160:3082-8. 2000
    ..We examined the associations of age, smoking status, body mass index (BMI), weight change during adulthood, physical activity, and alcohol intake with risk of CAP among men and women...
  78. pmc The association of serum lipids and inflammatory biomarkers with renal function in men with type II diabetes mellitus
    J Lin
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Kidney Int 69:336-42. 2006
    ....
  79. ncbi request reprint Effect of pravastatin on cardiovascular events in people with chronic kidney disease
    Marcello Tonelli
    Division of Nephrology, University of Alberta, 7 129 Clinical Science Building, 8440 112 St, Edmonton, Alberta T6G 2G3, Canada
    Circulation 110:1557-63. 2004
    ..The objective of this analysis was to determine whether pravastatin reduced the incidence of cardiovascular events in people with or at high risk for coronary disease and with concomitant moderate CKD...
  80. ncbi request reprint Screening, monitoring, and treatment of albuminuria: Public health perspectives
    Paul E de Jong
    Division of Nephrology, Department of Medicine, University Medical Center Groningen, Groningen University, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Am Soc Nephrol 17:2120-6. 2006
    ....
  81. ncbi request reprint Dietary factors and the risk of incident kidney stones in younger women: Nurses' Health Study II
    Gary C Curhan
    Channing Laboratory, Department of Medicine, Brigham and Womens Hospital, 181 Longwood Avenue, Boston, MA 02115, USA
    Arch Intern Med 164:885-91. 2004
    ..Recently, phytate has been suggested to play a role in stone formation. To our knowledge, no prospective information on the role of dietary factors and risk of kidney stone formation is available in younger women...
  82. ncbi request reprint Validity of International Classification of Diseases, Ninth Revision, Clinical Modification Codes for Acute Renal Failure
    Sushrut S Waikar
    Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Am Soc Nephrol 17:1688-94. 2006
    ..The excellent performance characteristics of ICD-9-CM codes for ARF-D suggest that administrative data sets may be particularly well suited for research endeavors that involve patients with ARF-D...
  83. ncbi request reprint Association of prevalent hypertension with 24-hour urinary excretion of calcium, citrate, and other factors
    Eric N Taylor
    Renal Division, Department of Medicine, Brigham Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Kidney Dis 47:780-9. 2006
    ..It has been proposed that increased urinary calcium excretion is a central feature of essential hypertension. Metabolic acidosis also may be associated with hypertension and decreases urinary citrate levels...
  84. ncbi request reprint Intake of n-6 and n-3 fatty acids and fish and risk of community-acquired pneumonia in US men
    Anwar T Merchant
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Am J Clin Nutr 82:668-74. 2005
    ..Essential fatty acids modulate inflammation and glucose metabolism and may alter infection risk...
  85. ncbi request reprint Nonsteroidal antiinflammatory drugs, acetaminophen, and the risk of cardiovascular events
    Andrew T Chan
    Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Circulation 113:1578-87. 2006
    ..Although randomized trials of cyclooxygenase-2 (COX-2) inhibitors have shown increased cardiovascular risk, studies of nonselective, nonsteroidal antiinflammatory drugs (NSAIDs) and acetaminophen have been inconsistent...
  86. ncbi request reprint Fatty acid intake and incident nephrolithiasis
    Eric N Taylor
    Channing Laboratory and Renal Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Kidney Dis 45:267-74. 2005
    ..It has been proposed that greater intake of EPA and DHA (through dietary sources or fish oil supplementation) may reduce the risk for kidney stone formation...
  87. ncbi request reprint Non-narcotic analgesic dose and risk of incident hypertension in US women
    John P Forman
    Renal Division, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Hypertension 46:500-7. 2005
    ..Because acetaminophen and nonsteroidal anti-inflammatory drugs are commonly used, they may contribute to the high prevalence of hypertension in the United States...
  88. ncbi request reprint Gemfibrozil for secondary prevention of cardiovascular events in mild to moderate chronic renal insufficiency
    Marcello Tonelli
    Division of Nephrology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Kidney Int 66:1123-30. 2004
    ....
  89. ncbi request reprint Angiotensin-converting enzyme inhibitor or angiotensin II type 1 receptor antagonist therapy is associated with prolonged patient and graft survival after renal transplantation
    Georg Heinze
    Core Unit of Medical Statistics and Informatics, Department of Nephrology, Medical University of Vienna, Austria
    J Am Soc Nephrol 17:889-99. 2006
    ..More frequent use of these medications may reduce the high incidence of death and renal allograft failure in these patients...
  90. pmc Higher levels of albuminuria within the normal range predict incident hypertension
    John P Forman
    Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Nephrol 19:1983-8. 2008
    ..The definition of normal albumin excretion should be reevaluated...
  91. ncbi request reprint Parathyroid hormone and the risk of incident hypertension
    Eric N Taylor
    Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Hypertens 26:1390-4. 2008
    ..We conducted a prospective study to examine the association between plasma intact parathyroid hormone levels and the subsequent risk of developing hypertension...
  92. ncbi request reprint Albuminuria: moving beyond traditional microalbuminuria cut-points
    Eric L Knight
    Curr Opin Nephrol Hypertens 12:283-4. 2003
  93. ncbi request reprint Differences in 24-hour urine composition between black and white women
    Eric N Taylor
    Channing Laboratory, Third Floor, Brigham and Women s Hospital, 181 Longwood Avenue, Boston, MA 02115, USA
    J Am Soc Nephrol 18:654-9. 2007
    ..These differences are not explained by differences in age, body mass index, or diet and may account for the lower incidence of both nephrolithiasis and osteoporosis in black women...
  94. ncbi request reprint Renin-angiotensin system polymorphisms and risk of hypertension: influence of environmental factors
    John P Forman
    Renal Division, The Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    J Clin Hypertens (Greenwich) 10:459-66. 2008
    ..These data suggest that demographic and dietary factors may influence the associations between RAS polymorphisms and hypertension and could explain heterogeneity in prior studies...
  95. ncbi request reprint Effect of pravastatin on loss of renal function in people with moderate chronic renal insufficiency and cardiovascular disease
    Marcello Tonelli
    University of Alberta, Edmonton, Alberta, Canada
    J Am Soc Nephrol 14:1605-13. 2003
    ..These findings require confirmation by a large randomized trial conducted specifically in people with chronic renal insufficiency...
  96. ncbi request reprint The association between gout and nephrolithiasis in men: The Health Professionals' Follow-Up Study
    Holly J Kramer
    Department of Preventive Medicine and Epidemiology, Division of Nephrology, Loyola University Medical Center, Maywood, Illinois, USA
    Kidney Int 64:1022-6. 2003
    ....
  97. ncbi request reprint High-normal blood pressure and microalbuminuria
    Eric L Knight
    Renal Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
    Am J Kidney Dis 41:588-95. 2003
    ....
  98. ncbi request reprint Frequency of use of acetaminophen, nonsteroidal anti-inflammatory drugs, and aspirin in US women
    Gary C Curhan
    Channing Laboratory, Department of Medicine, Brigham and Womens Hospital, Harvard Medical School, Harvard School of Public Health, Department of Epidemiology, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 11:687-93. 2002
    ..To determine the frequency of use of the three main classes of over-the-counter analgesics: acetaminophen, non-steroidal anti-inflammatory drugs, and aspirin in two large US female cohorts...
  99. ncbi request reprint Oxalate intake and the risk for nephrolithiasis
    Eric N Taylor
    Channing Laboratory, Third Floor, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Am Soc Nephrol 18:2198-204. 2007
    ..08 to 1.58) for men and 1.34 (95% CI 1.10 to 1.64) for older women. Oxalate intake and spinach were not associated with risk in younger women. These data do not implicate dietary oxalate as a major risk factor for nephrolithiasis...
  100. ncbi request reprint Declining mortality in patients with acute renal failure, 1988 to 2002
    Sushrut S Waikar
    Channing Laboratory, Brigham and Women s Hospital, 181 Longwood Avenue, Boston, MA 02115, USA
    J Am Soc Nephrol 17:1143-50. 2006
    ..4% in 1988 to 26.6% in 2002 (P < 0.001). This study provides evidence from an administrative database that the incidence of ARF and ARF-D is rising. Despite an increase in the degree of comorbidity, in-hospital mortality has declined...
  101. pmc Fatty acid intake and the risk of community-acquired pneumonia in U.S. women
    Michael Alperovich
    Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    Nutrition 23:196-202. 2007
    ..Fatty acid intake may influence community-acquired pneumonia risk by modulating the immune system. Our study prospectively examined the association between fatty acid intake and community-acquired pneumonia risk...

Research Grants16

  1. Risk Factors for Decline in Renal Function
    Gary Curhan; Fiscal Year: 2006
    ....
  2. Risk Factors for Recurrent Nephrolithiasis
    Gary Curhan; Fiscal Year: 2006
    ..The study design and use of existing data provide an efficient means to increase the scientific value of these cohorts and to test several hypotheses of public health importance. ..
  3. Risk Factors for Decline in Renal Function
    Gary Curhan; Fiscal Year: 2004
    ....
  4. Risk Factors for Recurrent Nephrolithiasis
    Gary Curhan; Fiscal Year: 2004
    ..The study design and use of existing data provide an efficient means to increase the scientific value of these cohorts and to test several hypotheses of public health importance. ..
  5. Risk Factors for Recurrent Nephrolithiasis
    Gary Curhan; Fiscal Year: 2002
    ..The study design and use of existing data provide an efficient means to increase the scientific value of these cohorts and to test several hypotheses of public health importance. ..
  6. ANALGESIC USE AND THE RISK OF CHRONIC RENAL FAILURE
    Gary Curhan; Fiscal Year: 2001
    ....
  7. ANALGESIC USE AND THE RISK OF CHRONIC RENAL FAILURE
    Gary Curhan; Fiscal Year: 1999
    ....
  8. ANALGESIC USE AND THE RISK OF CHRONIC RENAL FAILURE
    Gary Curhan; Fiscal Year: 2002
    ....
  9. Risk Factors for Decline in Renal Function
    Gary Curhan; Fiscal Year: 2007
    ....
  10. ANALGESIC USE AND THE RISK OF CHRONIC RENAL FAILURE
    Gary Curhan; Fiscal Year: 2000
    ....
  11. Risk Factors for Decline in Renal Function
    Gary Curhan; Fiscal Year: 2005
    ....
  12. Risk Factors for Recurrent Nephrolithiasis
    Gary Curhan; Fiscal Year: 2005
    ..The study design and use of existing data provide an efficient means to increase the scientific value of these cohorts and to test several hypotheses of public health importance. ..
  13. ANALGESIC USE AND THE RISK OF CHRONIC RENAL FAILURE
    Gary Curhan; Fiscal Year: 2000
    ....
  14. Risk Factors for Recurrent Nephrolithiasis
    Gary Curhan; Fiscal Year: 2003
    ..The study design and use of existing data provide an efficient means to increase the scientific value of these cohorts and to test several hypotheses of public health importance. ..