Daniel W Cramer

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Autoantibody profiling to identify biomarkers of key pathogenic pathways in mucinous ovarian cancer
    Liangdan Tang
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Eur J Cancer 46:170-9. 2010
  2. pmc Mumps and ovarian cancer: modern interpretation of an historic association
    Daniel W Cramer
    Department of Obstetrics and Gynecology Epidemiology Center, Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital BWH, Harvard Medical School, 221 Longwood Ave, RFB 366, Boston, MA 02115, USA
    Cancer Causes Control 21:1193-201. 2010
  3. pmc Coffee intake, variants in genes involved in caffeine metabolism, and the risk of epithelial ovarian cancer
    Joanne Kotsopoulos
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Causes Control 20:335-44. 2009
  4. pmc Talc use, variants of the GSTM1, GSTT1, and NAT2 genes, and risk of epithelial ovarian cancer
    Margaret A Gates
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:2436-44. 2008
  5. pmc Breast cancer susceptibility alleles and ovarian cancer risk in 2 study populations
    Margaret A Gates
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 124:729-33. 2009
  6. ncbi Incessant ovulation, mucin 1 immunity, and risk for ovarian cancer
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:30-5. 2007
  7. pmc Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer risk
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Carcinogenesis 30:2042-6. 2009
  8. pmc Genetic variation in the progesterone receptor gene and ovarian cancer risk
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Epidemiol 161:442-51. 2005
  9. ncbi Conditions associated with antibodies against the tumor-associated antigen MUC1 and their relationship to risk for ovarian cancer
    Daniel W Cramer
    Epidemiology Center, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:1125-31. 2005
  10. pmc Anti-MUC1 antibodies and ovarian cancer risk: prospective data from the Nurses' Health Studies
    Simone P Pinheiro
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 19:1595-601. 2010

Detail Information

Publications60

  1. pmc Autoantibody profiling to identify biomarkers of key pathogenic pathways in mucinous ovarian cancer
    Liangdan Tang
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Eur J Cancer 46:170-9. 2010
    ..Autoantibody profiling may have an unexpected utility in uncovering key signalling pathways that are dysregulated in the system of interest...
  2. pmc Mumps and ovarian cancer: modern interpretation of an historic association
    Daniel W Cramer
    Department of Obstetrics and Gynecology Epidemiology Center, Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital BWH, Harvard Medical School, 221 Longwood Ave, RFB 366, Boston, MA 02115, USA
    Cancer Causes Control 21:1193-201. 2010
    ..To explain this association, we investigated whether mumps might engender immunity to ovarian cancer through antibodies against the cancer-associated antigen MUC1 abnormally expressed in the inflamed parotid gland...
  3. pmc Coffee intake, variants in genes involved in caffeine metabolism, and the risk of epithelial ovarian cancer
    Joanne Kotsopoulos
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Causes Control 20:335-44. 2009
    ..Furthermore, we did not observe any clear gene-environment interactions between caffeine metabolizing genes and ovarian cancer. Future studies evaluating mechanisms by which coffee mediates this relationship are warranted...
  4. pmc Talc use, variants of the GSTM1, GSTT1, and NAT2 genes, and risk of epithelial ovarian cancer
    Margaret A Gates
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:2436-44. 2008
    ..These results suggest that women with certain genetic variants may have a higher risk of ovarian cancer associated with genital talc use. Additional research is needed on these interactions and the underlying biological mechanisms...
  5. pmc Breast cancer susceptibility alleles and ovarian cancer risk in 2 study populations
    Margaret A Gates
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 124:729-33. 2009
    ..16-1.18 per allele at the alpha=0.05 level in the pooled analysis. Our results do not provide strong support for an association between these breast cancer susceptibility alleles and epithelial ovarian cancer risk...
  6. ncbi Incessant ovulation, mucin 1 immunity, and risk for ovarian cancer
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:30-5. 2007
    ..In this study, we examined whether the total number of ovulatory cycles decreases the likelihood of anti-MUC1 antibodies and provides an immune basis for the association between "incessant ovulation" and ovarian cancer risk...
  7. pmc Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer risk
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Carcinogenesis 30:2042-6. 2009
    ..Of particular interest was the IGFBP3 SNP rs2270628, which was associated with both increased IGF1 plasma levels and higher ovarian cancer risk...
  8. pmc Genetic variation in the progesterone receptor gene and ovarian cancer risk
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Epidemiol 161:442-51. 2005
    ..76, 95% confidence interval: 0.62, 0.92). Associations were similar after stratifying by ovarian cancer histologies and risk factors...
  9. ncbi Conditions associated with antibodies against the tumor-associated antigen MUC1 and their relationship to risk for ovarian cancer
    Daniel W Cramer
    Epidemiology Center, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:1125-31. 2005
    ....
  10. pmc Anti-MUC1 antibodies and ovarian cancer risk: prospective data from the Nurses' Health Studies
    Simone P Pinheiro
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 19:1595-601. 2010
    ..Antibodies developed against tumor-like MUC1 in response to such events could be one way through which ovarian cancer risk factors operate...
  11. pmc Flavonoid intake and ovarian cancer risk in a population-based case-control study
    Margaret A Gates
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 124:1918-25. 2009
    ..However, given the findings of previous studies and the biologic plausibility of this association, additional studies are warranted...
  12. ncbi Ginkgo biloba and ovarian cancer prevention: epidemiological and biological evidence
    Bin Ye
    Laboratory of Gynecologic Oncology and Epidemiology, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, Dana Farber Cancer Center, USA
    Cancer Lett 251:43-52. 2007
    ..This combined epidemiological and biological data provide supportive evidence for further studies of the chemopreventive or therapeutic effects of Ginkgo and ginkgolides on ovarian cancer...
  13. pmc Activation of platelet-activating factor receptor and pleiotropic effects on tyrosine phospho-EGFR/Src/FAK/paxillin in ovarian cancer
    Margarita Aponte
    Laboratory of Gynecologic Oncology and Epidemiology, Department of Obstetrics and Gynecology and Reproductive Biology, Brigham and Women s Hospital, Dana Farber Cancer Center, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Res 68:5839-48. 2008
    ..We suggest that PAFR is an essential upstream target of Src and other signal pathways to control the PAF-mediated cancer progression...
  14. pmc Dairy foods and nutrients in relation to risk of ovarian cancer and major histological subtypes
    Melissa A Merritt
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Int J Cancer 132:1114-24. 2013
    ..The overall inverse association with high intake of calcium and the inverse associations of calcium and vitamin D with specific histological subtypes warrant further investigation...
  15. pmc Association of hexachlorobenzene (HCB), dichlorodiphenyltrichloroethane (DDT), and dichlorodiphenyldichloroethylene (DDE) with in vitro fertilization (IVF) outcomes
    Shruthi Mahalingaiah
    Department of Obstetrics, Gynecology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Environ Health Perspect 120:316-20. 2012
    ..Hexachlorobenzene (HCB), dichlorodiphenyltrichloroethane (DDT), and dichlorodiphenyldichloroethylene (DDE) are persistent chlorinated pesticides with endocrine activity that may adversely affect the early stages of human reproduction...
  16. pmc Duarte galactose-1-phosphate uridyl transferase genotypes are not associated with ovarian cancer risk
    Melissa A Merritt
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Fertil Steril 98:687-91. 2012
    ..To investigate whether galactose-1-phosphate uridyl transferase (GALT) variant genotypes were associated with epithelial ovarian cancer risk, and to determine if this association was modified by lactose intake...
  17. pmc Correlates of the preoperative level of CA125 at presentation of ovarian cancer
    Daniel W Cramer
    Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA, USA
    Gynecol Oncol 119:462-8. 2010
    ..We examined the effect of epidemiologic variables and tumor features on CA125 at diagnosis and their effects on survival...
  18. pmc MTHFR polymorphisms in relation to ovarian cancer risk
    Kathryn L Terry
    Ob Gyn Epidemiology Center, Brigham and Women s Hospital, Boston, MA 02115, USA
    Gynecol Oncol 119:319-24. 2010
    ..Thus, we examined ovarian cancer risk in relation to two functional polymorphisms (C677T and A1298C) in the MTHFR gene...
  19. pmc Androgen receptor cytosine, adenine, guanine repeats, and haplotypes in relation to ovarian cancer risk
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Res 65:5974-81. 2005
    ..Our results suggest that possession of two long AR alleles (> or = 22 CAG repeats) may be associated with increased risk of ovarian cancer compared with women with two short AR alleles (<22 CAG repeats)...
  20. pmc Telomere length and genetic variation in telomere maintenance genes in relation to ovarian cancer risk
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 21:504-12. 2012
    ..Shorter telomeres in peripheral blood leukocytes (PBL) have been associated with elevated cancer risk. Furthermore, genetic variants in and around the TERT gene have been implicated in carcinogenesis...
  21. doi Does a woman's educational attainment influence in vitro fertilization outcomes?
    Shruthi Mahalingaiah
    Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Fertil Steril 95:2618-20. 2011
    ....
  22. pmc Hormonal and reproductive risk factors for epithelial ovarian cancer by tumor aggressiveness
    Elizabeth M Poole
    Corresponding Author Elizabeth M Poole, Channing Laboratory, 181 Longwood Ave, 3rd Floor, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 22:429-37. 2013
    ....
  23. ncbi Identification of epithelial cell adhesion molecule autoantibody in patients with ovarian cancer
    Jae Hoon Kim
    Department of Obstetrics, Gynecology and Reproductive Biology, Division of Gynecologic Oncology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Clin Cancer Res 9:4782-91. 2003
    ..090 in 26 normal women. This investigation has shown that the Ep-CAM autoantibody was found to be associated with ovarian cancer and suggested that future research assessing its clinical usefulness would be worthwhile...
  24. pmc CA125 immune complexes in ovarian cancer patients with low CA125 concentrations
    Daniel W Cramer
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Clin Chem 56:1889-92. 2010
    ..Because CA125 and MUC1 are related members of the mucin family, we sought to determine whether CICs might also exist for CA125 and interfere with its clinical assay...
  25. pmc ABO blood group and incidence of epithelial ovarian cancer
    Margaret A Gates
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Int J Cancer 128:482-6. 2011
    ..Additional studies are needed to confirm this association and to explore the mechanisms through which blood group may influence ovarian cancer risk...
  26. pmc Blood and urine markers for ovarian cancer: a comprehensive review
    Kathryn L Terry
    Ob Gyn Center Epidemiology Center, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Boston, MA, USA
    Dis Markers 20:53-70. 2004
  27. ncbi Proteomic-based discovery and characterization of glycosylated eosinophil-derived neurotoxin and COOH-terminal osteopontin fragments for ovarian cancer in urine
    Bin Ye
    Laboratory of Gynecologic Oncology, Department of Obstetrics and Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Dana Farber Cancer Center, 221 Longwood Avenue, LMRC 601B, Boston, MA 02115, USA
    Clin Cancer Res 12:432-41. 2006
    ..The objective was to identify and characterize low molecular weight proteins/peptides in urine and their posttranslational modifications that might be used as a screening tool for ovarian cancer...
  28. pmc Assessing ovarian cancer risk when considering elective oophorectomy at the time of hysterectomy
    Allison F Vitonis
    Department of Obstetrics and Gynecology, Epidemiology Center, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Obstet Gynecol 117:1042-50. 2011
    ..To develop a risk-factor score that may provide additional guidance to women and their physicians regarding elective bilateral salpingo-oophorectomy at the time of hysterectomy...
  29. pmc ABO blood group and risk of epithelial ovarian cancer within the Ovarian Cancer Association Consortium
    Elizabeth M Poole
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Ave, 3rd Floor, Boston, MA 02115, USA
    Cancer Causes Control 23:1805-10. 2012
    ..Previous studies have examined the association between ABO blood group and ovarian cancer risk, with inconclusive results...
  30. pmc Ovarian cancer risk in relation to medical visits, pelvic examinations and type of health care provider
    Haim A Abenhaim
    School of Public Health, Harvard University, Boston, Mass, USA
    CMAJ 176:941-7. 2007
    ..Whether the current recommendations for ovarian cancer prevention and screening (annual history and physical examination) are effective has not been evaluated. We examined the relation between health care use and the risk of ovarian cancer...
  31. ncbi Pooling of case specimens to create standard serum sets for screening cancer biomarkers
    Steven J Skates
    Biostatistics Center, Massachusetts General Hospital, Boston, USA
    Cancer Epidemiol Biomarkers Prev 16:334-41. 2007
    ..We describe the creation and use of standard serum sets developed from healthy donors and pooled sera from ovarian, breast, and endometrial cancer cases...
  32. pmc The epidemiology of endometrial and ovarian cancer
    Daniel W Cramer
    Department of Obstetrics and Gynecology, Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Boston, MA 02115, USA
    Hematol Oncol Clin North Am 26:1-12. 2012
    ..Careful selection of patients for prophylactic oophorectomy for those women who are coming to hysterectomy for benign disease is an additional measure to consider for ovarian cancer...
  33. pmc Analysis of multiple-cycle data from couples undergoing in vitro fertilization: methodologic issues and statistical approaches
    Stacey A Missmer
    Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Epidemiology 22:497-504. 2011
    ..Given that risk factors associated with IVF success may also advance our understanding of the physiologic processes underlying conception, implantation, and gestation, the application of valid methods to these complex data is critical...
  34. pmc Tubal ligation, hysterectomy and epithelial ovarian cancer in the New England Case-Control Study
    Megan S Rice
    Department of Epidemiology, Harvard School of Public Health, Boston, MA Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA
    Int J Cancer 133:2415-21. 2013
    ..Additional research is necessary to understand the potential biologic mechanisms by which these procedures may reduce ovarian cancer risk...
  35. pmc Endometrial intraepithelial neoplasia: clinical correlates and outcomes
    Luwam G Semere
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Obstet Gynecol 118:21-8. 2011
    ..To estimate cancer outcome and outcome predictors of women with endometrial intraepithelial neoplasia (EIN)...
  36. pmc Use of nonsteroidal antiinflammatory agents and incidence of ovarian cancer in 2 large prospective cohorts
    Simone P Pinheiro
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Am J Epidemiol 169:1378-87. 2009
    ..In this large prospective study, the authors found no compelling evidence to support an association between regular use of aspirin, nonaspirin NSAIDs, or acetaminophen and ovarian cancer incidence...
  37. pmc Physical activity and semen quality among men attending an infertility clinic
    Lauren A Wise
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    Fertil Steril 95:1025-30. 2011
    ..To examine the association between regular physical activity and semen quality...
  38. ncbi Human progesterone receptor polymorphisms and implantation failure during in vitro fertilization
    Daniel W Cramer
    Department of Obstetrics, Gynecology and Reproductive Biology, Ob Gyn Epidemiology Center, 221 Longwood Avenue, Brigham and Women s Hospital, Boston, MA, USA
    Am J Obstet Gynecol 189:1085-92. 2003
    ..Polymorphic variants of the human progesterone receptor gene have been described, but their potential influence on in vitro fertilization outcome have not been studied...
  39. ncbi Interaction between CYP1A1 polymorphic variants and dietary exposures influencing ovarian cancer risk
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 12:187-90. 2003
    ..Significant interaction may exist between polymorphic variants of CYP1A1 and caffeine that could explain weak or inconsistent associations between caffeine and ovarian cancer when genotype has not been considered...
  40. ncbi Effects of lifetime exercise on the outcome of in vitro fertilization
    Stephanie N Morris
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital and Harvard Medical, Boston, Massachusetts, USA
    Obstet Gynecol 108:938-45. 2006
    ..To estimate whether exercise before the first cycle of in vitro fertilization (IVF) affects cycle outcomes...
  41. ncbi The epidemiology of endometriosis
    Daniel W Cramer
    Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Ann N Y Acad Sci 955:11-22; discussion 34-6, 396-406. 2002
    ....
  42. ncbi Osteopontin as a potential diagnostic biomarker for ovarian cancer
    Jae Hoon Kim
    Laboratory of Gynecologic Oncology, Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Boston, MA 02115, USA
    JAMA 287:1671-9. 2002
    ..Analyses involving complementary DNA (cDNA) microarray data can be used to identify up-regulated genes in cancer cells, whose products may then be further validated as potential biomarkers...
  43. pmc Puerperal mastitis: a reproductive event of importance affecting anti-mucin antibody levels and ovarian cancer risk
    Daniel W Cramer
    Department of Obstetrics, Gynecology and Reproductive Biology, Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, 221 Longwood Ave, RFB365, Boston, MA, 02115, USA
    Cancer Causes Control 24:1911-23. 2013
    ..Test the hypothesis that puerperal mastitis may alter immunity related to the mucin (MUC) family of glycoproteins and lower risk of ovarian cancer...
  44. pmc Folate, vitamin B(6) , vitamin B(12) , methionine and alcohol intake in relation to ovarian cancer risk
    Holly R Harris
    Brigham and Women s Hospital, Boston, MA, USA
    Int J Cancer 131:E518-29. 2012
    ..58-0.94; p(trend) = 0.012) subtypes. Overall, we observed no significant association between folate and ovarian cancer risk. One-carbon metabolism related nutrients, especially vitamin B(6) and methionine, may lower ovarian cancer risk...
  45. pmc Integration of cell phone imaging with microchip ELISA to detect ovarian cancer HE4 biomarker in urine at the point-of-care
    Shuqi Wang
    Demirci Bio Acoustic MEMS in Medicine BAMM Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Harvard MIT Health Sciences and Technology, Cambridge, MA 02139, USA
    Lab Chip 11:3411-8. 2011
    ....
  46. ncbi Haptoglobin-alpha subunit as potential serum biomarker in ovarian cancer: identification and characterization using proteomic profiling and mass spectrometry
    Bin Ye
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Dana Farber Cancer Institute, Dana Farber Harvard Cancer Center, Boston, MA 02115, USA
    Clin Cancer Res 9:2904-11. 2003
    ..An antibody was generated from the synthesized peptide for quantitative validation in the cases and controls. CA125 was determined and compared with the same set of specimens...
  47. doi The "reverse capture" autoantibody microarray : an innovative approach to profiling the autoantibody response to tissue-derived native antigens
    Joshua R Ehrlich
    Molecular Urology Laboratory, Division of Urology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Methods Mol Biol 441:175-92. 2008
    ..Here, we present a detailed description of the "reverse capture" autoantibody microarray for use with tissue-derived native antigens...
  48. ncbi Presence of talc in pelvic lymph nodes of a woman with ovarian cancer and long-term genital exposure to cosmetic talc
    Daniel W Cramer
    Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Obstet Gynecol 110:498-501. 2007
    ..Although epidemiologic studies suggest talc use may increase ovarian cancer risk, there is no proof that talc used externally reaches the pelvis...
  49. ncbi Early life menstrual characteristics and pregnancy experiences among women with and without major depression: the Harvard study of moods and cycles
    Bernard L Harlow
    Obstetrics and Gynecology Epidemiology Center at Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    J Affect Disord 79:167-76. 2004
    ..Other than premenstrual dysphoria, few studies have examined the extent to which basic characteristics of the menstrual cycle and the occurrence of other reproductive landmarks impact on the risk of major depression...
  50. pmc Point of failure as a predictor of in vitro fertilization treatment discontinuation
    Kimberly R Pearson
    Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA
    Fertil Steril 91:1483-5. 2009
    ....
  51. pmc Non-genomic biomarkers of risk in ovarian cancer
    Simone P Pinheiro
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Dis Markers 23:355-66. 2007
  52. pmc Molecular pathogenesis of endometrial and ovarian cancer
    Melissa A Merritt
    Brigham and Women s Hospital, Department of Obstetrics and Gynecology Epidemiology Center, Boston, MA, USA
    Cancer Biomark 9:287-305. 2010
    ..A consideration of molecular and other pathogenetic features, like epidemiology and histopathology, may provide a better understanding of endometrial and ovarian cancer...
  53. pmc Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens
    Daniel W Cramer
    Brigham and Women s Hospital, Ob Gyn, Division of Epidemiology, Boston, MA 02115, USA
    Cancer Prev Res (Phila) 4:365-74. 2011
    ..Despite many promising new markers for ovarian cancer, CA125 remains the single-best biomarker in the phase II and phase III specimens tested in this study...
  54. ncbi The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome
    Fabiola Medeiros
    Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Surg Pathol 30:230-6. 2006
    ..Investigative strategies targeting the fimbriated end of the fallopian tube should further define its role in the pathogenesis of familial and sporadic ovarian serous carcinomas...
  55. pmc Epidemiologic perspective on immune-surveillance in cancer
    Daniel W Cramer
    Obsterics Gynecology Epidemiology Center, Department of Obsterics and Gynecology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Curr Opin Immunol 23:265-71. 2011
    ..We review recently published data that suggest that immune mechanisms underlie most of these observed epidemiologic associations with cancer risk...
  56. doi Effect of alcohol consumption on in vitro fertilization
    Brooke V Rossi
    Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Obstet Gynecol 117:136-42. 2011
    ..To estimate whether alcohol use at the initiation of an in vitro fertilization (IVF) cycle is associated with IVF outcomes...
  57. ncbi Characteristics of patients with endometriosis in the United States and the United Kingdom
    Wendy Kuohung
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Fertil Steril 78:767-72. 2002
    ..To investigate differences in characteristics of patients with endometriosis in the United States and the United Kingdom...
  58. ncbi Polymorphisms of the estrogen-metabolizing genes CYP17 and catechol-O-methyltransferase and risk of epithelial ovarian cancer
    Elizabeth I O Garner
    Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Cancer Res 62:3058-62. 2002
    ..Confirmation in other populations and further exploration of potential pathogenetic mechanisms will be necessary...
  59. ncbi The epidemiology of endometriosis
    Stacey A Missmer
    Ob Gyn Epidemiology Center, Brigham and Women s Hospital, 121 Longwood Avenue, Boston, MA 02115, USA
    Obstet Gynecol Clin North Am 30:1-19, vii. 2003
    ..Finally, they offer a brief interpretation of these findings and suggest hypotheses for future research...
  60. ncbi A prospective study of dietary lactose and ovarian cancer
    Kathleen M Fairfield
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Int J Cancer 110:271-7. 2004
    ..Our findings provide some support for the hypothesis that lactose intake increases risk of epithelial ovarian cancer. However, the observed excess risk appeared limited to the serous subtype of ovarian cancer in our study...