Research Topics
| Daniel CramerSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Publications
The epidemiology of endometrial and ovarian cancerDaniel W Cramer
Department of Obstetrics and Gynecology, Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Boston, MA 02115, USA
Hematol Oncol Clin North Am 26:1-12. 2012..Careful selection of patients for prophylactic oophorectomy for those women who are coming to hysterectomy for benign disease is an additional measure to consider for ovarian cancer...
Activated networking of platelet activating factor receptor and FAK/STAT1 induces malignant potential in BRCA1-mutant at-risk ovarian epitheliumLifang Zhang
Obstetrics and Gynecology Department, Peking University People s Hospital, Beijing, China
Reprod Biol Endocrinol 8:74. 2010..The major objective of this study was to explore and determine whether platelet activating factor (PAF) and receptor associated networking pathways might significantly induce malignant potential in BRCA1-mutant at-risk epithelial cells...
Novel missense mutations of the Deleted-in-AZoospermia-Like (DAZL) gene in infertile women and menJoyce Y Tung
Human Embryonic Stem Cell Center, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California at San Francisco, San Francisco, CA 94143, USA
Reprod Biol Endocrinol 4:40. 2006..Recently, we showed that there are several common polymorphisms within the DAZL gene that are associated with age at ovarian failure/menopause and sperm count...
Serum and follicular fluid organochlorine concentrations among women undergoing assisted reproduction technologiesJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, USA
Environ Health 8:32. 2009....
The epidemiology of endometriosisDaniel W Cramer
Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Ann N Y Acad Sci 955:11-22; discussion 34-6, 396-406. 2002....
Conditions associated with antibodies against the tumor-associated antigen MUC1 and their relationship to risk for ovarian cancerDaniel W Cramer
Epidemiology Center, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 14:1125-31. 2005....
Presence of talc in pelvic lymph nodes of a woman with ovarian cancer and long-term genital exposure to cosmetic talcDaniel W Cramer
Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Obstet Gynecol 110:498-501. 2007..Although epidemiologic studies suggest talc use may increase ovarian cancer risk, there is no proof that talc used externally reaches the pelvis...
Determinants of early follicular phase gonadotrophin and estradiol concentrations in women of late reproductive ageD W Cramer
Obstetrics and Gynecology Epidemiology Center, Boston, MA 02115, USA
Hum Reprod 17:221-7. 2002..FSH and estradiol measured during the menstrual (basal) phase of cycles predict the success of infertility treatment; but the role of these hormones as markers for ovarian reserve in normal populations needs further study...
Carotenoids, antioxidants and ovarian cancer risk in pre- and postmenopausal womenD W Cramer
Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
Int J Cancer 94:128-34. 2001..Food items most strongly related to decreased risk for ovarian cancer were raw carrots and tomato sauce. Consumption of fruits, vegetables and food items high in carotene and lycopene may reduce the risk of ovarian cancer...
Serum prolactin and TSH in an in vitro fertilization population: is there a link between fertilization and thyroid function?D W Cramer
Ob Gyn Epidemiology Center, Department of Obstetrics, Gynecology and Reproductive Biology, 221 Longwood Avenue, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
J Assist Reprod Genet 20:210-5. 2003..Measurements of TSH and prolactin are generally included in the evaluation of female infertility, but their value in women coming to in vitro fertilization (IVF) has been questioned...
Correlates of the preoperative level of CA125 at presentation of ovarian cancerDaniel W Cramer
Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA, USA
Gynecol Oncol 119:462-8. 2010..We examined the effect of epidemiologic variables and tumor features on CA125 at diagnosis and their effects on survival...
CA125 immune complexes in ovarian cancer patients with low CA125 concentrationsDaniel W Cramer
Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA 02115, USA
Clin Chem 56:1889-92. 2010..Because CA125 and MUC1 are related members of the mucin family, we sought to determine whether CICs might also exist for CA125 and interfere with its clinical assay...
Epidemiologic perspective on immune-surveillance in cancerDaniel W Cramer
Obsterics Gynecology Epidemiology Center, Department of Obsterics and Gynecology, Brigham and Women s Hospital, Boston, MA 02115, USA
Curr Opin Immunol 23:265-71. 2011..We review recently published data that suggest that immune mechanisms underlie most of these observed epidemiologic associations with cancer risk...
Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimensDaniel W Cramer
Brigham and Women s Hospital, Ob Gyn, Division of Epidemiology, Boston, MA 02115, USA
Cancer Prev Res (Phila) 4:365-74. 2011..Despite many promising new markers for ovarian cancer, CA125 remains the single-best biomarker in the phase II and phase III specimens tested in this study...
p53 autoantibodies as potential detection and prognostic biomarkers in serous ovarian cancerKaren S Anderson
Cancer Vaccine Center, Department of Medical Oncology, Dana Farber Cancer Institute, HIM416, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 19:859-68. 2010..This study examined the value of serum p53 autoantibodies (p53-AAb) as detection and prognostic biomarkers in ovarian cancer...
Polymorphisms in the vitamin D receptor and risk of ovarian cancer in four studiesShelley S Tworoger
Channing Laboratory, Boston, MA 02115, USA
Cancer Res 69:1885-91. 2009..34-1.28), and among women with the Ff or ff genotype the OR was 0.71 (95% CI, 0.43-1.18). Our results of an association with the Fok1 VDR polymorphism further support a role of the vitamin D pathway in ovarian carcinogenesis...
A proteomic analysis of IVF follicular fluid in women <or=32 years oldStephanie J Estes
Department of Obstetrics and Gynecology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115 5804, USA
Fertil Steril 92:1569-78. 2009..To address the lack of predictors of IVF success by using proteomic biometrics...
Serum and follicular fluid hormone levels during in vitro fertilization after short- or long-course treatment with a gonadotropin-releasing hormone agonistY Y Bo-Abbas
Reproductive Endocrine Unit, National Center for Infertility Research, Massachusetts General Hospital, Boston, USA
Fertil Steril 75:694-9. 2001..CONCLUSION(S): Serum LH and FF A are significantly higher in the flare regimen in comparison with the down-regulation regimen. Circulating LH appears to play a role in determining FF A concentration...
Reproductive hormones, cancers, and conditions in relation to a common genetic variant of luteinizing hormoneD W Cramer
Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA 02115, USA
Hum Reprod 15:2103-7. 2000..While there is no evidence from this study that v-LH increases risk for ovarian or breast cancer, we conclude that possession of v-LH may impact on some aspects of reproductive history and LH concentrations...
Prevalence and predictors of depressive symptoms in older premenopausal women: the Harvard Study of Moods and CyclesB L Harlow
Harvard Medical School, Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Boston, Mass 02115, USA
Arch Gen Psychiatry 56:418-24. 1999..The Harvard Study of Moods and Cycles is a community-based cohort study designed to evaluate the relationship between major depression and changes in menstrual and ovarian function...
Early follicular phase hormone levels in relation to patterns of alcohol, tobacco, and coffee useJ Lucero
Department of Obstetrics and Gynecology, University of California at San Francisco Medical Center, San Francisco, California, USA
Fertil Steril 76:723-9. 2001..CONCLUSION(S): Coffee consumption and total caffeine use may increase early follicular phase E2 levels independent of related habits of alcohol or tobacco use...
Application of protein microarrays for multiplexed detection of antibodies to tumor antigens in breast cancerKaren S Anderson
Cancer Vaccine Center, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
J Proteome Res 7:1490-9. 2008..Here, we present the first demonstration of the application of programmable protein microarray ELISAs for the rapid identification of breast cancer autoantibodies...
Integrated analysis of multiple microarray datasets identifies a reproducible survival predictor in ovarian cancerPanagiotis A Konstantinopoulos
Division of Hematology Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
PLoS ONE 6:e18202. 2011..Public data integration may help overcome challenges in clinical implementation of microarray profiles. We integrated several ovarian cancer datasets to identify a reproducible predictor of survival...
Leptin in relation to carcinoma in situ of the breast: a study of pre-menopausal cases and controlsC S Mantzoros
Division of Endocrinology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Int J Cancer 80:523-6. 1999..73-4.21) for the second control-defined tertile and 1.54 (0.46-5.16) for the third control-defined tertile relative to the first. Thus, leptin does not appear to increase the risk of pre-menopausal breast cancer in situ substantially...
Ethnic background and in vitro fertilization outcomesK Bendikson
Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
Int J Gynaecol Obstet 88:342-6. 2005..To compare IVF outcomes among women of different ethnic backgrounds...
Prospective study of talc use and ovarian cancerD M Gertig
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
J Natl Cancer Inst 92:249-52. 2000..In this study, we conducted a prospective analysis of perineal talc use and the risk of ovarian cancer...
Psychotropic medication use and risk of epithelial ovarian cancerB L Harlow
Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Cancer Epidemiol Biomarkers Prev 7:697-702. 1998....
Genital talc exposure and risk of ovarian cancerD W Cramer
Obstetrics Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA 02115, USA
Int J Cancer 81:351-6. 1999....
A candidate precursor to serous carcinoma that originates in the distal fallopian tubeY Lee
Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
J Pathol 211:26-35. 2007....
Prostasin, a potential serum marker for ovarian cancer: identification through microarray technologyS C Mok
Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Natl Cancer Inst 93:1458-64. 2001..We used microarray technology to identify overexpressed genes for secretory proteins as potential serum biomarkers and selected prostasin, a serine protease normally secreted by the prostate gland, for further study...
Recent trends in assisted reproductive techniques and associated outcomesD W Cramer
Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Obstet Gynecol 95:61-6. 2000..We examined recent trends in success rates for assisted reproduction and determined the influence of changes in patient selection and treatment characteristics on these trends...
A case-control study of galactose consumption and metabolism in relation to ovarian cancerD W Cramer
Ob Gyn Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Cancer Epidemiol Biomarkers Prev 9:95-101. 2000..62-76.60). We conclude that, whereas adult consumption of lactose carries no clear risk for the disease, certain genetic or biochemical features of galactose metabolism may influence disease risk for particular types of ovarian cancer...
Ginkgo biloba and ovarian cancer prevention: epidemiological and biological evidenceBin Ye
Laboratory of Gynecologic Oncology and Epidemiology, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, Dana Farber Cancer Center, USA
Cancer Lett 251:43-52. 2007..This combined epidemiological and biological data provide supportive evidence for further studies of the chemopreventive or therapeutic effects of Ginkgo and ginkgolides on ovarian cancer...
Infertility, fertility drugs, and ovarian cancer: a pooled analysis of case-control studiesRoberta B Ness
University of Pittsburgh School of Public Health, Pittsburgh, PA 15261, USA
Am J Epidemiol 155:217-24. 2002..10, 2.71) and unknown cause of infertility (OR = 1.19, 95% CI: 1.00, 1.40) increased cancer risk. These data suggest a role for specific biologic causes of infertility, but not for fertility drugs in overall risk for ovarian cancer...
Incessant ovulation, mucin 1 immunity, and risk for ovarian cancerKathryn L Terry
Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 16:30-5. 2007..In this study, we examined whether the total number of ovulatory cycles decreases the likelihood of anti-MUC1 antibodies and provides an immune basis for the association between "incessant ovulation" and ovarian cancer risk...
Ovarian cancer risk in relation to medical visits, pelvic examinations and type of health care providerHaim A Abenhaim
School of Public Health, Harvard University, Boston, Mass, USA
CMAJ 176:941-7. 2007..Whether the current recommendations for ovarian cancer prevention and screening (annual history and physical examination) are effective has not been evaluated. We examined the relation between health care use and the risk of ovarian cancer...
Talc use, variants of the GSTM1, GSTT1, and NAT2 genes, and risk of epithelial ovarian cancerMargaret A Gates
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 17:2436-44. 2008..These results suggest that women with certain genetic variants may have a higher risk of ovarian cancer associated with genital talc use. Additional research is needed on these interactions and the underlying biological mechanisms...
Activation of platelet-activating factor receptor and pleiotropic effects on tyrosine phospho-EGFR/Src/FAK/paxillin in ovarian cancerMargarita Aponte
Laboratory of Gynecologic Oncology and Epidemiology, Department of Obstetrics and Gynecology and Reproductive Biology, Brigham and Women s Hospital, Dana Farber Cancer Center, Harvard Medical School, Boston, Massachusetts 02115, USA
Cancer Res 68:5839-48. 2008..We suggest that PAFR is an essential upstream target of Src and other signal pathways to control the PAF-mediated cancer progression...
Osteopontin as a potential diagnostic biomarker for ovarian cancerJae Hoon Kim
Laboratory of Gynecologic Oncology, Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Boston, MA 02115, USA
JAMA 287:1671-9. 2002..Analyses involving complementary DNA (cDNA) microarray data can be used to identify up-regulated genes in cancer cells, whose products may then be further validated as potential biomarkers...
Genetic variation in the progesterone receptor gene and ovarian cancer riskKathryn L Terry
Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Am J Epidemiol 161:442-51. 2005..76, 95% confidence interval: 0.62, 0.92). Associations were similar after stratifying by ovarian cancer histologies and risk factors...
Proteomic-based discovery and characterization of glycosylated eosinophil-derived neurotoxin and COOH-terminal osteopontin fragments for ovarian cancer in urineBin Ye
Laboratory of Gynecologic Oncology, Department of Obstetrics and Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Dana Farber Cancer Center, 221 Longwood Avenue, LMRC 601B, Boston, MA 02115, USA
Clin Cancer Res 12:432-41. 2006..The objective was to identify and characterize low molecular weight proteins/peptides in urine and their posttranslational modifications that might be used as a screening tool for ovarian cancer...
Risk of ovarian cancer in the United States in relation to anthropometric measures: does the association depend on menopausal status?Hannah Kuper
International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, UK
Cancer Causes Control 13:455-63. 2002..To elucidate the association between anthropometric measures and ovarian cancer risk...
Identification of epithelial cell adhesion molecule autoantibody in patients with ovarian cancerJae-hoon Kim
Department of Obstetrics, Gynecology and Reproductive Biology, Division of Gynecologic Oncology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Clin Cancer Res 9:4782-91. 2003..090 in 26 normal women. This investigation has shown that the Ep-CAM autoantibody was found to be associated with ovarian cancer and suggested that future research assessing its clinical usefulness would be worthwhile...
Does tubal sterilization influence the subsequent risk of menorrhagia or dysmenorrhea?Bernard L Harlow
Department of Obstetrics and Gynecology, the Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Fertil Steril 77:754-60. 2002..To evaluate the relation between tubal ligation, change in menstrual cycle characteristics, and early follicular phase hormones...
Osteopontin as an adjunct to CA125 in detecting recurrent ovarian cancerJohn O Schorge
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical School, Dallas, Texas 75390, USA
Clin Cancer Res 10:3474-8. 2004..The purpose of this study was to test the hypothesis that OPN is a clinically useful adjunct to CA125 in detecting recurrent ovarian cancer...
Haptoglobin-alpha subunit as potential serum biomarker in ovarian cancer: identification and characterization using proteomic profiling and mass spectrometryBin Ye
Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Dana Farber Cancer Institute, Dana Farber Harvard Cancer Center, Boston, MA 02115, USA
Clin Cancer Res 9:2904-11. 2003..An antibody was generated from the synthesized peptide for quantitative validation in the cases and controls. CA125 was determined and compared with the same set of specimens...
Reproductive factors and ovarian cancer risk in Jewish BRCA1 and BRCA2 mutation carriers (United States)Francesmary Modugno
Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
Cancer Causes Control 14:439-46. 2003..To determine whether oral contraceptive (OC) use, childbearing, breastfeeding and tubal ligation differ between ovarian cancer cases with and without a BRCA1/2 mutation...
Polymorphisms of the estrogen-metabolizing genes CYP17 and catechol-O-methyltransferase and risk of epithelial ovarian cancerElizabeth I O Garner
Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
Cancer Res 62:3058-62. 2002..Confirmation in other populations and further exploration of potential pathogenetic mechanisms will be necessary...
The epidemiology of endometriosisStacey A Missmer
Ob Gyn Epidemiology Center, Brigham and Women s Hospital, 121 Longwood Avenue, Boston, MA 02115, USA
Obstet Gynecol Clin North Am 30:1-19, vii. 2003..Finally, they offer a brief interpretation of these findings and suggest hypotheses for future research...
The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndromeFabiola Medeiros
Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA
Am J Surg Pathol 30:230-6. 2006..Investigative strategies targeting the fimbriated end of the fallopian tube should further define its role in the pathogenesis of familial and sporadic ovarian serous carcinomas...
Interaction between CYP1A1 polymorphic variants and dietary exposures influencing ovarian cancer riskKathryn L Terry
Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Cancer Epidemiol Biomarkers Prev 12:187-90. 2003..Significant interaction may exist between polymorphic variants of CYP1A1 and caffeine that could explain weak or inconsistent associations between caffeine and ovarian cancer when genotype has not been considered...
Characteristics of patients with endometriosis in the United States and the United KingdomWendy Kuohung
Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Fertil Steril 78:767-72. 2002..S. and the U.K. support the universality of the disease process. Despite a variety of treatments, most patients from both groups still experienced pain from their endometriosis at the time of the survey...
Association of galactose-1-phosphate uridyltransferase activity and N314D genotype with the risk of ovarian cancerMarc T Goodman
Epidemiology Section, Cancer Etiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu 96813, USA
Am J Epidemiol 156:693-701. 2002..42, 1.41). This study did not support the hypothesis that reduced galactose metabolism is a risk factor for ovarian cancer, although increased GALT activity attenuated the inverse association of oral contraceptive pill use with risk...
Human progesterone receptor polymorphisms and implantation failure during in vitro fertilizationDaniel W Cramer
Department of Obstetrics, Gynecology and Reproductive Biology, Ob Gyn Epidemiology Center, 221 Longwood Avenue, Brigham and Women s Hospital, Boston, MA, USA
Am J Obstet Gynecol 189:1085-92. 2003..Polymorphic variants of the human progesterone receptor gene have been described, but their potential influence on in vitro fertilization outcome have not been studied...
Early life menstrual characteristics and pregnancy experiences among women with and without major depression: the Harvard study of moods and cyclesBernard L Harlow
Obstetrics and Gynecology Epidemiology Center at Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
J Affect Disord 79:167-76. 2004..Other than premenstrual dysphoria, few studies have examined the extent to which basic characteristics of the menstrual cycle and the occurrence of other reproductive landmarks impact on the risk of major depression...
A prospective study of dietary lactose and ovarian cancerKathleen M Fairfield
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Int J Cancer 110:271-7. 2004..Our findings provide some support for the hypothesis that lactose intake increases risk of epithelial ovarian cancer. However, the observed excess risk appeared limited to the serous subtype of ovarian cancer in our study...
Effects of lifetime exercise on the outcome of in vitro fertilizationStephanie N Morris
Department of Obstetrics and Gynecology, Brigham and Women's Hospital and Harvard Medical, Boston, Massachusetts, USA
Obstet Gynecol 108:938-45. 2006..level of evidence: ii-2...
Variants in Deleted in AZoospermia-Like (DAZL) are correlated with reproductive parameters in men and womenJoyce Y Tung
Department of Obstetrics, Program in Human Embryonic Stem Cell Biology, Center for Reproductive Sciences, University of California at San Francisco, San Francisco, CA 94143, USA
Hum Genet 118:730-40. 2006..Single SNP and haplotype analysis suggested that SNPs in the DAZL gene may act jointly to affect common reproductive characteristics in the human population...
Androgen receptor cytosine, adenine, guanine repeats, and haplotypes in relation to ovarian cancer riskKathryn L Terry
Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Cancer Res 65:5974-81. 2005..Our results suggest that possession of two long AR alleles (> or = 22 CAG repeats) may be associated with increased risk of ovarian cancer compared with women with two short AR alleles (<22 CAG repeats)...
Pooling of case specimens to create standard serum sets for screening cancer biomarkersSteven J Skates
Biostatistics Center, Massachusetts General Hospital, Boston, USA
Cancer Epidemiol Biomarkers Prev 16:334-41. 2007..We describe the creation and use of standard serum sets developed from healthy donors and pooled sera from ovarian, breast, and endometrial cancer cases...
Risk of spontaneous abortion in women with childhood exposure to parental cigarette smokeJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI 48109, USA
Am J Epidemiol 166:571-5. 2007..Future large studies of pregnancy loss are needed that can distinguish women's tobacco smoke exposure in childhood from that taking place in utero...
Talc and anti-MUC1 antibodiesJoshua Muscat
Cancer Epidemiol Biomarkers Prev 14:2679; author reply 2680. 2005
Blood and urine markers for ovarian cancer: a comprehensive reviewKathryn L Terry
Ob-Gyn Center Epidemiology Center, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital, Boston, MA, USA
Dis Markers 20:53-70. 2004
The "reverse capture" autoantibody microarray : an innovative approach to profiling the autoantibody response to tissue-derived native antigensJoshua R Ehrlich
Molecular Urology Laboratory, Division of Urology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Methods Mol Biol 441:175-92. 2008..Here, we present a detailed description of the "reverse capture" autoantibody microarray for use with tissue-derived native antigens...
Consortium analysis of 7 candidate SNPs for ovarian cancerSusan J Ramus
Translational Research Laboratory, University College London EGA Institute for Women s Health, London, United Kingdom
Int J Cancer 123:380-8. 2008..These null results for SNPs identified from relatively large initial studies shows the importance of replicating associations by a consortium approach...
Non-genomic biomarkers of risk in ovarian cancerSimone P Pinheiro
Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
Dis Markers 23:355-66. 2007
Research Grants
- EPIDEMIOLOGIC AND BIOLOGIC PREDICTORS OF IVF SUCCESSDaniel Cramer; Fiscal Year: 2002....
- Genes, Hormones & Environment in an Ovarian Cancer ModelDaniel Cramer; Fiscal Year: 2007..Our continued goal is to identify modifiable risk factors and chemo preventive agents for a common and lethal cancer in women. ..
- MUC-1 related cancer immunity: determinants and predictive significanceDaniel Cramer; Fiscal Year: 2007..The findings of our study could provide the basis for developing a safe cancer- preventing vaccine for ovarian cancer and perhaps other MUC1-expressing tumors. ..
- Partners Southwestern Clinical Epidemiology/ValidationDaniel Cramer; Fiscal Year: 2007....
- Risk for New onset of Depression in Perimenopausal WomenDaniel Cramer; Fiscal Year: 2009..abstract_text> ..
- OVARIAN CANCER RISK AND HYPERGONADOTROPIC HYPOGONADISMDaniel Cramer; Fiscal Year: 2002..The investigators point out that only large, comprehensive epidemiologic studies capable of examining these factors within histologic subtypes are likely to succeed in identifying preventive mechanisms. ..
- OVARIAN CANCER RISK AND HYPERGONADOTROPIC HYPOGONADISMDaniel Cramer; Fiscal Year: 1993..The role of galactose rich foods in ovarian cancer etiology is particularly important because of a substantial increase in the use of these foods in the United States...
- MUC-1 related cancer immunity: determinants and predictive significanceDaniel Cramer; Fiscal Year: 2009..The findings of our study could provide the basis for developing a safe cancer- preventing vaccine for ovarian cancer and perhaps other MUC1-expressing tumors. ..
