Steven D Colan

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. ncbi The ventricular volume variability study of the Pediatric Heart Network: study design and impact of beat averaging and variable type on the reproducibility of echocardiographic measurements in children with chronic dilated cardiomyopathy
    Steven D Colan
    Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Echocardiogr 25:842-854.e6. 2012
  2. ncbi Epidemiology and cause-specific outcome of hypertrophic cardiomyopathy in children: findings from the Pediatric Cardiomyopathy Registry
    Steven D Colan
    Department of Cardiology, Children s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    Circulation 115:773-81. 2007
  3. ncbi Hypertrophic cardiomyopathy in childhood
    Steven D Colan
    Department of Cardiology, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Heart Fail Clin 6:433-44, vii-iii. 2010
  4. ncbi Surgical aortic valvuloplasty in children and adolescents with aortic regurgitation: acute and intermediate effects on aortic valve function and left ventricular dimensions
    Emile A Bacha
    Department of Cardiac Surgery, Children s Hospital Boston and Harvard Medical School, Boston, Mass 02115, USA
    J Thorac Cardiovasc Surg 135:552-9, 559.e1-3. 2008
  5. ncbi Fetal aortic valve stenosis and the evolution of hypoplastic left heart syndrome: patient selection for fetal intervention
    Kaarin Mäkikallio
    Department of Cardiology, Children s Hospital, Harvard Medical School, Boston, MA, USA
    Circulation 113:1401-5. 2006
  6. ncbi Fetal tricuspid valve size and growth as predictors of outcome in pulmonary atresia with intact ventricular septum
    Joshua W Salvin
    Department of Cardiology, Cardiac ICU Office, Farley 6, Children s Hospital Boston, 300 Longwood Ave, Boston, Massachusetts 02115, USA
    Pediatrics 118:e415-20. 2006
  7. ncbi Left ventricular diastolic function in children and young adults with congenital aortic valve disease
    Kevin G Friedman
    Department of Cardiology, Children s Hospital Boston and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 111:243-9. 2013
  8. ncbi Association of left ventricular dilation at listing for heart transplant with postlisting and early posttransplant mortality in children with dilated cardiomyopathy
    Tajinder P Singh
    Department of Cardiology, Children s Hospital Boston, Boston, Mass, USA
    Circ Heart Fail 2:591-8. 2009
  9. ncbi Improving outcomes in fetuses and neonates with congenital displacement (Ebstein's malformation) or dysplasia of the tricuspid valve
    Doff B McElhinney
    Department of Cardiology, Children's Hospital Boston, Boston, Massachusetts, USA
    Am J Cardiol 96:582-6. 2005
  10. ncbi Left heart growth, function, and reintervention after balloon aortic valvuloplasty for neonatal aortic stenosis
    Doff B McElhinney
    Department of Cardiology, Children's Hospital, and Harvard Medical School, Boston, Mass 02115, USA
    Circulation 111:451-8. 2005

Detail Information

Publications72

  1. ncbi The ventricular volume variability study of the Pediatric Heart Network: study design and impact of beat averaging and variable type on the reproducibility of echocardiographic measurements in children with chronic dilated cardiomyopathy
    Steven D Colan
    Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Echocardiogr 25:842-854.e6. 2012
    ....
  2. ncbi Epidemiology and cause-specific outcome of hypertrophic cardiomyopathy in children: findings from the Pediatric Cardiomyopathy Registry
    Steven D Colan
    Department of Cardiology, Children s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    Circulation 115:773-81. 2007
    ..Current information on the epidemiology and outcomes of hypertrophic cardiomyopathy (HCM) in children is limited by disease diversity and small case series...
  3. ncbi Hypertrophic cardiomyopathy in childhood
    Steven D Colan
    Department of Cardiology, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Heart Fail Clin 6:433-44, vii-iii. 2010
    ..Although most of the available information concerning treatment and prevention of sudden death is derived in adults, management of children requires consideration of the differences in age-specific risk/benefit ratios...
  4. ncbi Surgical aortic valvuloplasty in children and adolescents with aortic regurgitation: acute and intermediate effects on aortic valve function and left ventricular dimensions
    Emile A Bacha
    Department of Cardiac Surgery, Children s Hospital Boston and Harvard Medical School, Boston, Mass 02115, USA
    J Thorac Cardiovasc Surg 135:552-9, 559.e1-3. 2008
    ..Surgical aortic valvuloplasty is increasingly employed in the management of children and adolescents with aortic regurgitation, but the durability of this approach and factors associated with outcome are not well defined...
  5. ncbi Fetal aortic valve stenosis and the evolution of hypoplastic left heart syndrome: patient selection for fetal intervention
    Kaarin Mäkikallio
    Department of Cardiology, Children s Hospital, Harvard Medical School, Boston, MA, USA
    Circulation 113:1401-5. 2006
    ..The aim of this study was to define echocardiographic features associated with progression of midgestation fetal AS to HLHS...
  6. ncbi Fetal tricuspid valve size and growth as predictors of outcome in pulmonary atresia with intact ventricular septum
    Joshua W Salvin
    Department of Cardiology, Cardiac ICU Office, Farley 6, Children s Hospital Boston, 300 Longwood Ave, Boston, Massachusetts 02115, USA
    Pediatrics 118:e415-20. 2006
    ..The objective of this study was to determine whether the size and rate of growth of the fetal tricuspid valve predict neonatal anatomy and biventricular repair...
  7. ncbi Left ventricular diastolic function in children and young adults with congenital aortic valve disease
    Kevin G Friedman
    Department of Cardiology, Children s Hospital Boston and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 111:243-9. 2013
    ..In conclusion, DD is common in young patients with AS and AS+AR but not in those with pure AR. A greater LV mass and previous aortic valve dilation were associated with DD...
  8. ncbi Association of left ventricular dilation at listing for heart transplant with postlisting and early posttransplant mortality in children with dilated cardiomyopathy
    Tajinder P Singh
    Department of Cardiology, Children s Hospital Boston, Boston, Mass, USA
    Circ Heart Fail 2:591-8. 2009
    ....
  9. ncbi Improving outcomes in fetuses and neonates with congenital displacement (Ebstein's malformation) or dysplasia of the tricuspid valve
    Doff B McElhinney
    Department of Cardiology, Children's Hospital Boston, Boston, Massachusetts, USA
    Am J Cardiol 96:582-6. 2005
    ..To improve outcomes in this group of high-risk patients, novel approaches to management may be indicated...
  10. ncbi Left heart growth, function, and reintervention after balloon aortic valvuloplasty for neonatal aortic stenosis
    Doff B McElhinney
    Department of Cardiology, Children's Hospital, and Harvard Medical School, Boston, Mass 02115, USA
    Circulation 111:451-8. 2005
    ..Reintervention for residual/recurrent AS or iatrogenic AR is relatively common, particularly during the first year after BAVP, but aortic valve replacement during early childhood is seldom necessary...
  11. ncbi Report from The International Society for Nomenclature of Paediatric and Congenital Heart Disease: cardiovascular catheterisation for congenital and paediatric cardiac disease (Part 1 - Procedural nomenclature)
    Lisa Bergersen
    Department of Cardiology, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Cardiol Young 21:252-9. 2011
    ..Part 2 will cover the nomenclature of complications associated with interventional cardiology as treatment for paediatric and congenital cardiac disease...
  12. ncbi Aortic translocation for the management of double-outlet right ventricle and pulmonary stenosis with dextrocardia: technique to avoid coronary insufficiency
    Victor Bautista-Hernandez
    Department of Cardiac Surgery, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Ann Thorac Surg 89:633-5. 2010
    ....
  13. ncbi Factors associated with establishing a causal diagnosis for children with cardiomyopathy
    Gerald F Cox
    Division of Genetics, Department of Medicine, Children's Hospital, Boston, Massachusetts, USA
    Pediatrics 118:1519-31. 2006
    ..Although not widely used, skeletal muscle biopsy may yield a cause for some patients with hypertrophic cardiomyopathy and for patients suspected of having a mitochondrial disorder...
  14. ncbi Myocyte apoptosis occurs early during the development of pressure-overload hypertrophy in infant myocardium
    Yeong Hoon Choi
    Department of Anesthesiology and Perioperative and Pain Medicine, Children s Hospital Boston, and Harvard Medical School, Boston, Mass 02115, USA
    J Thorac Cardiovasc Surg 137:1356-62, 1362.e1-3. 2009
    ..This study examined the hypothesis that myocyte loss occurs during compensatory hypertrophic growth in the developing infant myocardium subjected to progressive pressure overload...
  15. ncbi Reproducibility of echocardiographic diagnosis of left ventricular noncompaction
    Susan F Saleeb
    Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Echocardiogr 25:194-202. 2012
    ..Limited studies exist on the reproducibility of diagnosing LVNC...
  16. ncbi Relationship of magnetic resonance imaging estimation of myocardial iron to left ventricular systolic and diastolic function in thalassemia
    Benedetta Leonardi
    Department of Cardiology, Children s Hospital Boston, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, USA
    JACC Cardiovasc Imaging 1:572-8. 2008
    ..We sought to evaluate whether echocardiographic diastolic function indices correlate with myocardial iron and systolic function in patients with transfusion-dependent thalassemia (TDT) who are at risk for cardiomyopathy...
  17. ncbi Comparison of echocardiographic and cardiac magnetic resonance imaging measurements of functional single ventricular volumes, mass, and ejection fraction (from the Pediatric Heart Network Fontan Cross-Sectional Study)
    Renee Margossian
    Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 104:419-28. 2009
    ..Echocardiographic and CMR measurements of FSV EF demonstrate similar interobserver reproducibility, whereas measurements of FSV mass and LV diastolic volume are more reproducible by CMR...
  18. ncbi An echocardiographic model predicting severity of aortic regurgitation in congenital heart disease
    Rebecca S Beroukhim
    Department of Cardiology, Children s Hospital Boston, Boston, MA 02115, USA
    Circ Cardiovasc Imaging 3:542-9. 2010
    ....
  19. ncbi Subtle abnormalities in contractile function are an early manifestation of sarcomere mutations in dilated cardiomyopathy
    Neal K Lakdawala
    Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Circ Cardiovasc Genet 5:503-10. 2012
    ..By studying mutation carriers before a clinical diagnosis develops, we characterize the early manifestations of sarcomere mutations in DCM and investigate how these manifestations differ from sarcomere mutations associated with HCM...
  20. ncbi Cardiac magnetic resonance versus routine cardiac catheterization before bidirectional glenn anastomosis in infants with functional single ventricle: a prospective randomized trial
    David W Brown
    Department of Cardiology, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
    Circulation 116:2718-25. 2007
    ..Because catheterization is invasive and exposes patients to ionizing radiation, cardiac magnetic resonance (CMR) may be a safe and effective alternative...
  21. ncbi Predictors of coronary artery visualization in Kawasaki disease
    Renee Margossian
    Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Echocardiogr 24:53-9. 2011
    ..Small series have established high specificity and sensitivity for detecting abnormalities, yet visualization rates of individual CA segments and factors associated with success are unknown...
  22. ncbi Utility of exercise stress echocardiography in pediatric cardiac transplant recipients: a single-center experience
    Ming Hui Chen
    Department of Cardiology, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
    J Heart Lung Transplant 31:517-23. 2012
    ..Therefore, the aim of this study was to assess the feasibility and utility of ESE in excluding ANG-detected epicardial CAD at our center, where ESE has been implemented since 2007...
  23. ncbi Correlation of exercise response in repaired coarctation of the aorta to left ventricular mass and geometry
    Eric V Krieger
    Department of Cardiology, Boston Children s Hospital, and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts Cardiovascular Division, Brigham and Women s Hospital, and Department of Medicine, Harvard Medical School, Boston, Massachusetts Electronic address
    Am J Cardiol 111:406-11. 2013
    ..001). In conclusion, HRE was associated with increased LVMVR, even after adjusting for multiple covariates...
  24. ncbi Fetal diagnosis of interrupted aortic arch
    Melanie Vogel
    Department of Cardiology, Children s Hospital Boston, Boston, Massachusetts, USA
    Am J Cardiol 105:727-34. 2010
    ..Despite the diagnostic challenges, the frequency of prenatal diagnosis of the IAA is increasing...
  25. ncbi Left ventricular remodeling and improvement in diastolic function after balloon aortic valvuloplasty for congenital aortic stenosis
    Kevin G Friedman
    Department of Cardiology, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Circ Cardiovasc Interv 5:549-54. 2012
    ..In congenital aortic stenosis, chronic pressure load has detrimental effects on left ventricular (LV) systolic and diastolic function. Reduction in LV pressure load with balloon aortic valvuloplasty (BAVP) may improve diastolic function...
  26. ncbi Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy
    Carolyn Y Ho
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    N Engl J Med 363:552-63. 2010
    ..In animal models, profibrotic genetic pathways are activated early, before hypertrophic remodeling. Data showing early profibrotic responses to sarcomere-gene mutations in patients with hypertrophic cardiomyopathy are lacking...
  27. ncbi Sudden unexpected death after balloon valvuloplasty for congenital aortic stenosis
    David W Brown
    Department of Cardiology, Children s Hospital, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 56:1939-46. 2010
    ..The aims of this study were to determine the incidence and risk factors of sudden unexpected death (SUD) after balloon aortic valvuloplasty (BAVP) for congenital aortic stenosis (AS) and to assess the effect of exercise restriction...
  28. ncbi Circulating matrix metalloproteinases in adolescents with hypertrophic cardiomyopathy and ventricular arrhythmia
    Justin P Zachariah
    Department of Cardiology, Children s Hospital Boston and Department of Pediatrics, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA
    Circ Heart Fail 5:462-6. 2012
    ..We explored differences in circulating markers of extracellular matrix turnover between young HCM patients with versus without history of serious arrhythmia...
  29. ncbi Non-geometric echocardiographic indices of ventricular function in patients with a Fontan circulation
    Jonathan Rhodes
    Children Hospital Boston and Harvard Medical School, Boston, Massachusetts, USA
    J Am Soc Echocardiogr 24:1213-9. 2011
    ..The purpose of this study was to compare these nongeometric indices of ventricular function to cardiac magnetic resonance (CMR) measurements of ventricular ejection fraction (EF)...
  30. ncbi Cardiac allograft function during the first year after transplantation in rejection-free children and young adults
    Fatima I Lunze
    Departments of Cardiology, Boston Children s Hospital, Boston, MA 02115, USA
    Circ Cardiovasc Imaging 5:756-64. 2012
    ..We sought to assess the recovery of left (LV) and right ventricular (RV) function during the first year after HT in children and young adults using pulsed-wave tissue Doppler imaging...
  31. ncbi Resource utilization after introduction of a standardized clinical assessment and management plan
    Kevin G Friedman
    Department of Cardiology, Children s Hospital Boston and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
    Congenit Heart Dis 5:374-81. 2010
    ..Based on periodic review of systemically collected data the SCAMP is designed to be modified to improve its own algorithm. One of the objectives of a SCAMP is to identify and reduce resource utilization and patient care costs...
  32. ncbi Technical performance scores in congenital cardiac operations: a quality assessment initiative
    John M Karamichalis
    Department of Cardiac Surgery, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts, USA
    Ann Thorac Surg 94:1317-23; discussion 1323. 2012
    ..The purpose of this study was the development and implementation of a system for measuring technical performance in the majority of congenital cardiac operations to be used as a surgeon's self-assessment tool...
  33. ncbi Echocardiographic predictors of mitral stenosis-related death or intervention in infants
    Elif Seda Selamet Tierney
    Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA 02155, USA
    Am Heart J 156:384-90. 2008
    ..Among patients diagnosed with MS in early infancy, echocardiographic factors associated with MS-related intervention or death have not been determined...
  34. ncbi Challenges in echocardiographic assessment of mitral regurgitation in children after repair of atrioventricular septal defect
    Ashwin Prakash
    Department of Cardiology, Children s Hospital, Boston, MA 02115, USA
    Pediatr Cardiol 33:205-14. 2012
    ..The utility of regurgitant volume and fraction was severely limited by poor interobserver agreement and frequently negative values...
  35. ncbi Morphology of bicuspid aortic valve in children and adolescents
    Susan M Fernandes
    Department of Cardiology, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
    J Am Coll Cardiol 44:1648-51. 2004
    ....
  36. ncbi Bicuspid aortic valve and associated aortic dilation in the young
    Susan Fernandes
    Department of Cardiology, Children s Hospital, Boston, MA 02115, USA
    Heart 98:1014-9. 2012
    ..Young patients with BAV can have significant aortic dilation that places them at risk for morbidity and mortality...
  37. ncbi Changes in left atrioventricular valve geometry after surgical repair of complete atrioventricular canal
    Elisabeth Kaza
    Division of Cardiac Surgery and Cardiology, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
    J Thorac Cardiovasc Surg 143:1117-24. 2012
    ..We sought to determine the changes in left atrioventricular valve geometry after surgical repair that may predispose to regurgitation...
  38. ncbi Bicuspid aortic valve morphology and interventions in the young
    Susan M Fernandes
    Department of Cardiology, Children s Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 49:2211-4. 2007
    ..The aim of this study was to determine whether the morphologic subtype of bicuspid aortic valve (BAV) is associated with valve intervention in the young...
  39. ncbi The longitudinal course of cardiomyopathy in Friedreich's ataxia during childhood
    Alaina Kipps
    Department of Cardiology, Boston, MA 02115, USA
    Pediatr Cardiol 30:306-10. 2009
    ..This study aimed to define the longitudinal course of the cardiac abnormalities with FA diagnosed during childhood and to correlate the presence of cardiomyopathy with clinical and genetic factors...
  40. ncbi Electrocardiographic features of sarcomere mutation carriers with and without clinically overt hypertrophic cardiomyopathy
    Neal K Lakdawala
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Am J Cardiol 108:1606-13. 2011
    ..However, owing to the limited sensitivity of ECG and echocardiographic screening, genetic testing is required to definitively identify at-risk family members...
  41. ncbi Validation and re-evaluation of a discriminant model predicting anatomic suitability for biventricular repair in neonates with aortic stenosis
    Steven D Colan
    Department of Cardiology, Children s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 47:1858-65. 2006
    ..The purpose of this study was to validate and re-evaluate our previously reported scoring systems for predicting optimal management in neonates with aortic stenosis (AS)...
  42. ncbi Diastolic function in children with Kawasaki disease
    Elif Seda Selamet Tierney
    Department of Cardiology, Children s Hospital Boston, and Department of Pediatrics, Harvard Medical School, Boston, MA 02155, United States
    Int J Cardiol 148:309-12. 2011
    ..The purpose of this study was to determine whether diastolic function is impaired in KD patients and whether there are any clinical correlates...
  43. ncbi Evidence of adverse ventricular interdependence in patients with atrial septal defects
    Roxanne E Walker
    Department of Cardiology, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
    Am J Cardiol 93:1374-7, A6. 2004
    ..Thus, LV dysfunction associated with RV volume overload is secondary to altered chamber geometry and decreased myofiber preload. This physiology is immediately reversible and is independent of heart rate and afterload...
  44. ncbi Association between congenital cardiovascular malformations and neuroblastoma
    Rani E George
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA
    J Pediatr 144:444-8. 2004
    ..We explored the association between neuroblastoma and congenital cardiovascular malformations (CCM), previously described in case reports...
  45. ncbi Long-term predictors of aortic root dilation and aortic regurgitation after arterial switch operation
    Marcy L Schwartz
    Department of Cardiology, Children s Hospital, 300 Longwood Avenue, Boston, Mass 02115, USA
    Circulation 110:II128-32. 2004
    ..Neo-aortic root dilation (ARD) and neo-aortic regurgitation (AR) may be progressive after arterial switch operation (ASO) for d-loop transposition of the great arteries (dTGA). We sought to identify predictors of ARD and AR after ASO...
  46. ncbi Serum cardiac troponin and subclinical cardiac status in pediatric chronic renal failure
    Steven E Lipshultz
    Department of Cardiology, Children s Hospital, Boston, Massachusetts, USA
    Pediatrics 112:79-86. 2003
    ..Pediatric patients are ideal for studies of the relationship between uremia and heart disease because they are unlikely to have cardiac risk factors other than uremia...
  47. ncbi Endothelial pulse amplitude testing: feasibility and reproducibility in adolescents
    Elif Seda Selamet Tierney
    Department of Cardiology, Children s Hospital, Boston, MA 02155, USA
    J Pediatr 154:901-5. 2009
    ..To test prospectively the reproducibility and feasibility of endothelial pulse amplitude testing (Endo-PAT), a novel Food and Drug Administration-approved technology, in healthy adolescents...
  48. ncbi Clinical outcomes and utility of cardiac catheterization prior to superior cavopulmonary anastomosis
    David W Brown
    Department of Cardiology, Children s Hospital, Boston, MA 02115, USA
    J Thorac Cardiovasc Surg 126:272-81. 2003
    ....
  49. ncbi Coronary artery dimensions in febrile children without Kawasaki disease
    Juan Carlos G Muniz
    Department of Cardiology at Children s Hospital Boston, Boston, MA and the Department of Pediatrics, Harvard Medical School, Boston, MA, USA
    Circ Cardiovasc Imaging 6:239-44. 2013
    ..However, CA dimensions for febrile children are unknown. We compared CA dimensions in children with febrile illnesses other than KD to those of normal afebrile children and to KD patients...
  50. ncbi Familial dilated cardiomyopathy caused by an alpha-tropomyosin mutation: the distinctive natural history of sarcomeric dilated cardiomyopathy
    Neal K Lakdawala
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 55:320-9. 2010
    ..We sought to further define the role of sarcomere mutations in dilated cardiomyopathy (DCM) and associated clinical phenotypes...
  51. ncbi Cardiac complications associated with the treatment of patients with congenital cardiac disease: consensus definitions from the Multi-Societal Database Committee for Pediatric and Congenital Heart Disease
    Emile Antoine Bacha
    Department of Cardiac Surgery, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cardiol Young 18:196-201. 2008
    ..Clinicians caring for patients with congenital cardiac disease will be able to use this list for databases, quality improvement initiatives, reporting of complications, and comparing strategies for treatment...
  52. ncbi Recombinant human growth hormone treatment for dilated cardiomyopathy in children
    Doff B McElhinney
    Department of Cardiology, Children s Hospital, 300 Longwood Ave, Boston, MA 02115, USA
    Pediatrics 114:e452-8. 2004
    ..We undertook this study to determine the effects of recombinant human GH on LV function and mass among children with stable LV dysfunction attributable to DCM...
  53. ncbi Accuracy of echocardiography in low birth weight infants with congenital heart disease
    Adam L Dorfman
    Department of Cardiology, Children's Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
    Pediatrics 115:102-7. 2005
    ..5 kg. As surgical and transcatheter interventions are extended to this population, heightened awareness of clinicians to pitfalls of echocardiography in this group of patients is warranted...
  54. ncbi Familial restrictive cardiomyopathy with skeletal abnormalities
    Marcy L Schwartz
    Department of Cardiology, Children s Hospital, Boston, Massachusetts 02115, USA
    Am J Cardiol 92:636-9. 2003
    ..Consistent with the poor prognosis encountered for children with restrictive cardiomyopathy, 2 children in this family died, whereas a third was symptomatic by age 3 years...
  55. ncbi A prospective phase II trial of vinblastine and methotrexate in multivessel intraluminal pulmonary vein stenosis in infants and children
    Maliha Rehman
    Department of Cardiology, Children s Hospital, Boston, MA, USA
    Congenit Heart Dis 6:608-23. 2011
    ..To determine the safety and efficacy of the chemotherapeutic agents vinblastine and methotrexate in the treatment of children with progressive multivessel intraluminal pulmonary vein stenosis (PVS)...
  56. ncbi Noninvasive serial evaluation of myocardial mechanics in pressure overload hypertrophy of rabbit myocardium
    Adrian M Moran
    Department of Cardiology, Harvard Medical School, Boston, MA 02115, USA
    Herz 28:52-62. 2003
    ..CONCLUSIONS: This novel noninvasive method for determination of myocardial mechanics allows for serial evaluation of cardiac function and the determination of the time course from compensated hypertrophy to myocyte failure...
  57. ncbi Echocardiographic assessment of the right ventricular response to hypertension in neonates on the basis of average-shaped contraction models
    Edward N Marcus
    Department of Cardiology, Children's Hospital and the Department of Pediatrics, Harvard Medical School, Boston, USA
    J Am Soc Echocardiogr 15:1145-53. 2002
    ..CONCLUSION: Reconstructed-shape contraction models throughout 1 cardiac cycle identify altered patterns of RV contraction in the presence of pulmonary hypertension...
  58. ncbi Cardiovascular disease: cause of morbidity and mortality in adult survivors of childhood cancers
    Ming Hui Chen
    Department of Cardiology, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
    Circ Res 108:619-28. 2011
    ..Basic and translational research is urgently needed to clarify pathophysiologic mechanisms of late cardiac effects and to develop therapies to improve both long-term survival and quality of life of adults cured of pediatric cancers...
  59. ncbi Balloon dilation of severe aortic stenosis in the fetus: potential for prevention of hypoplastic left heart syndrome: candidate selection, technique, and results of successful intervention
    Wayne Tworetzky
    Department of Cardiology, Children s Hospital Boston, 300 Longwood Ave, Boston MA 02115, USA
    Circulation 110:2125-31. 2004
    ..Fetuses meeting the first criterion are undefined, and previous reports of fetal AS dilation have not evaluated the impact of intervention on in utero growth of left heart structures...
  60. ncbi Rationale and design of a randomized clinical trial of beta-blocker therapy (atenolol) versus angiotensin II receptor blocker therapy (losartan) in individuals with Marfan syndrome
    Ronald V Lacro
    Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Am Heart J 154:624-31. 2007
    ..Recent studies in an FBN1-targeted mouse model of MFS with aortic disease similar to that seen in humans showed that treatment with losartan normalized aortic root growth and aortic wall architecture...
  61. ncbi Report from The International Society for Nomenclature of Paediatric and Congenital Heart Disease: cardiovascular catheterisation for congenital and paediatric cardiac disease (Part 2 - Nomenclature of complications associated with interventional cardiolo
    Lisa Bergersen
    Department of Cardiology, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Cardiol Young 21:260-5. 2011
    ..Part 2 will cover the nomenclature of complications associated with interventional cardiology as treatment for paediatric and congenital cardiac disease...
  62. ncbi Randomized trial of pulsed corticosteroid therapy for primary treatment of Kawasaki disease
    Jane W Newburger
    Department of Cardiology, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 356:663-75. 2007
    ..Studies have suggested that primary corticosteroid therapy might be beneficial and that adverse events are infrequent with short-term use...
  63. ncbi Theoretical and empirical derivation of cardiovascular allometric relationships in children
    Thierry Sluysmans
    Dept. of Cardiology, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
    J Appl Physiol 99:445-57. 2005
    ..Overall, the relationship between cardiac output and body size is the fundamental driving factor in cardiovascular allometry...
  64. ncbi Donald Charles Fyler: 1924–2011
    Jane W Newburger
    Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
    Cardiol Young 21:485-9. 2011
    ....
  65. ncbi The nomenclature, definition and classification of cardiac structures in the setting of heterotaxy
    Jeffrey P Jacobs
    The Congenital Heart Institute of Florida, All Children s Hospital Children s Hospital of Tampa, University of South Florida College of Medicine, Cardiac Surgical Associates, Saint Petersburg 33701, USA
    Cardiol Young 17:1-28. 2007
    ..It is only by utilizing this stepwise and logical progression of analysis that it becomes possible to describe correctly, and to classify properly, patients with heterotaxy...
  66. ncbi Usefulness of the pediatric electrocardiogram in detecting left ventricular hypertrophy: results from the Prospective Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection (P2C2 HIV) multicenter study
    Shannon M Rivenes
    Department of Pediatrics, Division of Pediatric Cardiology, Baylor College of Medicine Texas Children s Hospital, Houston, Tex 77030, USA
    Am Heart J 145:716-23. 2003
    ..This study prospectively assesses the usefulness of the pediatric ECG as a screening modality for LVH...
  67. ncbi The incidence of pediatric cardiomyopathy in two regions of the United States
    Steven E Lipshultz
    Golisano Children s Hospital at Strong and University of Rochester Medical Center, and the Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    N Engl J Med 348:1647-55. 2003
    ..Population-based data on the incidence of pediatric cardiomyopathy are rare because of the lack of large, prospective studies...
  68. ncbi Postmortem cardiomegaly and echocardiographic measurements of left ventricular size and function in children infected with the human immunodeficiency virus. The Prospective P2C2 HIV Multicenter Study
    Debra L Kearney
    Department of Pathology, Baylor College of Medicine, Houston, TX 77030, USA
    Cardiovasc Pathol 12:140-8. 2003
    ..We sought to determine the postmortem prevalence, clinicopathologic relationships and importance of cardiomegaly in HIV-infected children...
  69. ncbi Improved outcomes of pediatric dilated cardiomyopathy with utilization of heart transplantation
    Anna E Tsirka
    Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA
    J Am Coll Cardiol 44:391-7. 2004
    ..Utilization of heart transplantation has led to improved survival after the diagnosis of pediatric DCM...
  70. ncbi Incidence, causes, and outcomes of dilated cardiomyopathy in children
    Jeffrey A Towbin
    Texas Children's Hospital, Baylor College of Medicine, Houston, USA
    JAMA 296:1867-76. 2006
    ..Race, sex, and age affect the incidence of disease. Most children do not have a known cause of DCM, which limits the potential for disease-specific therapies...
  71. ncbi Clinical features and outcomes of childhood hypertrophic cardiomyopathy: results from a national population-based study
    Alan W Nugent
    Department of Cardiology, Royal Children's Hospital, Melbourne, Australia
    Circulation 112:1332-8. 2005
    ..Ventricular outflow tract obstruction is common. The clinical status of long-term survivors is good. This population-based study identifies children with hypertrophic cardiomyopathy who are at risk of adverse events...
  72. ncbi Incidence of cardiac abnormalities in children with human immunodeficiency virus infection: The prospective P2C2 HIV study
    Thomas J Starc
    Department of Pediatrics, Division of Pediatric Cardiology, Presbyterian Hospital/Columbia University, College of Physicians and Surgeons, New York City, New York, USA
    J Pediatr 141:327-34. 2002
    ..We recommend that HIV-infected children undergo routine echocardiographic surveillance for cardiac abnormalities...