Research Topics
| Andrea L CiaranelloSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
| Collaborators
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Detail Information
Publications
Cost-effectiveness of World Health Organization 2010 guidelines for prevention of mother-to-child HIV transmission in ZimbabweAndrea L Ciaranello
Medical Practice Evaluation Center, Divisions of Infectious Disease, Massachusetts General Hospital, Boston, MA 02114, USA
Clin Infect Dis 56:430-46. 2013..We projected clinical impacts, costs, and cost-effectiveness of WHO-recommended PMTCT strategies in Zimbabwe...
What will it take to eliminate pediatric HIV? Reaching WHO target rates of mother-to-child HIV transmission in Zimbabwe: a model-based analysisAndrea L Ciaranello
Division of Infectious Disease, Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, USA
PLoS Med 9:e1001156. 2012..We investigated uptake of prevention of MTCT (PMTCT) services, infant feeding recommendations, and specific drug regimens necessary to achieve this goal in Zimbabwe...
Severe morbidity and mortality in untreated HIV-infected children in a paediatric care programme in Abidjan, Côte d'Ivoire, 2004-2009Sophie Desmonde
INSERM, U897 and Institut de Santé Publique, Epidémiologie et Développement ISPED, Universite Victor Segalen Bordeaux 2, Bordeaux, France
BMC Infect Dis 11:182. 2011..Clinical evolution of HIV-infected children who have not yet initiated antiretroviral treatment (ART) is poorly understood in Africa. We describe severe morbidity and mortality of untreated HIV-infected children...
WHO 2010 guidelines for prevention of mother-to-child HIV transmission in Zimbabwe: modeling clinical outcomes in infants and mothersAndrea L Ciaranello
Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, United States of America
PLoS ONE 6:e20224. 2011..The Zimbabwean national prevention of mother-to-child HIV transmission (PMTCT) program provided primarily single-dose nevirapine (sdNVP) from 2002-2009 and is currently replacing sdNVP with more effective antiretroviral (ARV) regimens...
Early infant HIV-1 diagnosis programs in resource-limited settings: opportunities for improved outcomes and more cost-effective interventionsAndrea L Ciaranello
Division of Infectious Disease, Massachusetts General Hospital, and Center for AIDS Research, Harvard Medical School, Boston, MA, USA
BMC Med 9:59. 2011....
First-line antiretroviral therapy after single-dose nevirapine exposure in South Africa: a cost-effectiveness analysis of the OCTANE trialAndrea L Ciaranello
Division of Infectious Disease, Massachusetts General Hospital, Boston, 02114, USA
AIDS 25:479-92. 2011..nevirapine-based antiretroviral therapy (ART) among women previously exposed to single-dose nevirapine to prevent mother-to-child HIV transmission. However, lopinavir/ritonavir is 12 times costlier than nevirapine...
Providing health care services to the formerly homeless: a quasi-experimental evaluationAndrea L Ciaranello
Massachusetts General Hospital, USA
J Health Care Poor Underserved 17:441-61. 2006..At 6 months, residents at the intervention sites also experienced improved blood pressure control. There was no intervention effect on residents' access to specialists or on physical functioning, mental health, or dental health...
Effectiveness of pediatric antiretroviral therapy in resource-limited settings: a systematic review and meta-analysisAndrea L Ciaranello
The Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Clin Infect Dis 49:1915-27. 2009..We sought to derive pooled estimates of the 12-month rate of virologic suppression (HIV RNA, <400 copies/mL) and gain in CD4 cell percentage (DeltaCD4%) for children initiating ART in resource-limited settings...
Access to medications and medical care after participation in HIV clinical trials: a systematic review of trial protocols and informed consent documentsAndrea L Ciaranello
Division of Infectious Disease, Massachusetts General Hospital, Boston, MA 02114, USA
HIV Clin Trials 10:13-24. 2009..We describe the frequency with which these posttrial services are described in the protocols and informed consent forms (ICFs) of antiretroviral drug (ARV) trials...
Antiretroviral drugs for preventing mother-to-child transmission of HIV in sub-Saharan Africa: balancing efficacy and infant toxicityAndrea L Ciaranello
Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
AIDS 22:2359-69. 2008..We sought to identify the currently recommended regimen to prevent mother-to-child transmission that optimally balances risks of pediatric HIV infection and neurologic mitochondrial toxicity...
Vesiculopapular rashAndrea L Ciaranello
Division of Infectious Disease, Massachusetts General Hospital, Boston, MA 02114, USA
Clin Infect Dis 43:1308, 1368-9. 2006
Cost-effectiveness of laboratory monitoring in sub-Saharan Africa: a review of the current literatureRochelle P Walensky
Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Clin Infect Dis 51:85-92. 2010....
Scaling up the 2010 World Health Organization HIV Treatment Guidelines in resource-limited settings: a model-based analysisRochelle P Walensky
Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
PLoS Med 7:e1000382. 2010..This paper considers what to do first in resource-limited settings where immediate implementation of all of the WHO recommendations is not feasible...
The clinical and economic impact of genotype testing at first-line antiretroviral therapy failure for HIV-infected patients in South AfricaJulie H Levison
Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA
Clin Infect Dis 56:587-97. 2013..After adherence counseling, these patients may safely and effectively continue first-line ART, thereby delaying more expensive second-line ART...
Quantifying the risks and benefits of efavirenz use in HIV-infected women of childbearing age in the USAH E Hsu
Harvard Medical School, Boston, MA, USA
HIV Med 12:97-108. 2011..The aim of the study was to quantify the benefits (life expectancy gains) and risks (efavirenz-related teratogenicity) associated with using efavirenz in HIV-infected women of childbearing age in the USA...
