Research Topics
| Niteesh K ChoudhrySummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Detail Information
Publications
A systematic review of reference pricing: implications for US prescription drug spendingJoy Li Yueh Lee
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Am J Manag Care 18:e429-37. 2012..These results suggest that reference pricing may be an attractive policy strategy for the US healthcare system...
The impact of reducing cardiovascular medication copayments on health spending and resource utilizationNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
J Am Coll Cardiol 60:1817-24. 2012..The aim of this study was to evaluate the impact of reductions in statin and clopidogrel copayments on cardiovascular resource utilization, major coronary events, and insurer spending...- Cost-related medication underuse: prevalence among hospitalized managed care patientsNiteesh K Choudhry
Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
J Hosp Med 7:104-9. 2012..Estimates of cost-related medication underuse come largely from surveys of ambulatory patients. Hospitalized patients may be vulnerable to cost-related underuse and its consequences, but have been subject to little investigation... - Should patients receive secondary prevention medications for free after a myocardial infarction? An economic analysisNiteesh K Choudhry
Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts, USA
Health Aff (Millwood) 26:186-94. 2007..Our analysis suggests that covering combination therapy for such patients will save both lives and money... 
Statins in elderly patients with acute coronary syndrome: an analysis of dose and class effects in typical practiceNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Heart 93:945-51. 2007..To compare the effectiveness of statins of different treatment intensity used to treat elderly patients with acute coronary syndrome (ACS) in typical care settings...- Full coverage for preventive medications after myocardial infarctionNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
N Engl J Med 365:2088-97. 2011..Adherence to medications that are prescribed after myocardial infarction is poor. Eliminating out-of-pocket costs may increase adherence and improve outcomes... - The economic consequences of non-evidence-based clopidogrel useNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Am Heart J 155:904-9. 2008..However, little is known about the appropriateness of that use. Overuse of clopidogrel could have important implications for health care quality and drug expenditures... - Warfarin prescribing in atrial fibrillation: the impact of physician, patient, and hospital characteristicsNiteesh K Choudhry
Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts, USA
Am J Med 119:607-15. 2006..The study investigated the determinants of warfarin use in patients with atrial fibrillation (AF)... - Trends in adherence to secondary prevention medications in elderly post-myocardial infarction patientsNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Pharmacoepidemiol Drug Saf 17:1189-96. 2008..Poor levels of medication adherence for patients with coronary heart disease (CHD) have been documented but it is unclear whether adherence has improved over time... - The implications of therapeutic complexity on adherence to cardiovascular medicationsNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
Arch Intern Med 171:814-22. 2011..Our objective was to estimate the extent of prescribing and filling complexity in patients prescribed a cardiovascular medication and to evaluate its association with adherence... - Rationale and design of the Post-MI FREEE trial: a randomized evaluation of first-dollar drug coverage for post-myocardial infarction secondary preventive therapiesNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Am Heart J 156:31-6. 2008..Removing patient out-of-pocket drug costs may increase adherence, improve clinical outcomes, and even reduce overall health costs for high-risk patients. The existing data are inadequate to assess whether this strategy is effective... - Comparison of the impact of the Atrial Fibrillation Follow-Up Investigation of Rhythm Management trial on prescribing patterns: a time-series analysisNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Ann Pharmacother 42:1563-72. 2008..Because of superior safety and lower cost, rate control is now the recommended strategy for the management of most elderly, high-risk AF patients... - Assessing the evidence for value-based insurance designNiteesh K Choudhry
Harvard Medical School, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Health Aff (Millwood) 29:1988-94. 2010..Maximizing the benefits of value-based insurance design will require mechanisms to target appropriate copayment reductions, offset short-run cost outlays, and expand its use to other health services... - At Pitney Bowes, value-based insurance design cut copayments and increased drug adherenceNiteesh K Choudhry
Harvard Medical School, USA
Health Aff (Millwood) 29:1995-2001. 2010..Our study thus provides an empirical basis for the use of this approach to improve the quality of health care... - Measuring concurrent adherence to multiple related medicationsNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Boston, MA 02120, USA
Am J Manag Care 15:457-64. 2009..To propose standardized methods for measuring concurrent adherence to multiple related medications and to apply these definitions to a cohort of patients with diabetes mellitus... - The cost-effectiveness of C-reactive protein testing and rosuvastatin treatment for patients with normal cholesterol levelsNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
J Am Coll Cardiol 57:784-91. 2011..We sought to evaluate the cost-effectiveness of applying the JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) trial results into clinical practice... - Impact of adverse events on prescribing warfarin in patients with atrial fibrillation: matched pair analysisNiteesh K Choudhry
Harvard Medical School and Brigham and Women s Hospital, Boston 02120, USA
BMJ 332:141-5. 2006..To quantify the influence of physicians' experiences of adverse events in patients with atrial fibrillation who were taking warfarin... - Drug company-sponsored patient assistance programs: a viable safety net?Niteesh K Choudhry
Brigham and Women s Hospital BWH, Division of Pharmacoepidemiology and Pharmacoeconomics, in Boston, Massachusetts, USA
Health Aff (Millwood) 28:827-34. 2009..A better understanding of PAPs might clarify their role in improving access to medications, the adequacy of existing public programs, and their impact on cost-effective medication use... - Cost-effectiveness of providing full drug coverage to increase medication adherence in post-myocardial infarction Medicare beneficiariesNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Circulation 117:1261-8. 2008.... - State generic substitution laws can lower drug outlays under MedicaidWilliam H Shrank
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Health Aff (Millwood) 29:1383-90. 2010..Although these consent requirements are probably intended to increase patient autonomy, policy makers should consider the sizable opportunity costs... - Prevalence of atrial fibrillation and warfarin use in older patients receiving hemodialysisWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Nephrol 25:341-53. 2012..Little is known about the use of warfarin in hemodialysis (HD) patients with atrial fibrillation (AF). We studied temporal trends of AF among older HD patients, and of warfarin use among those with AF... - Effectiveness and safety of warfarin initiation in older hemodialysis patients with incident atrial fibrillationWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Clin J Am Soc Nephrol 6:2662-8. 2011..Although generally recommended in atrial fibrillation (AF) patients, the effectiveness and safety of oral anticoagulation in dialysis patients with AF is unknown... - Patient, physician, and payment predictors of statin adherenceDavid C Chan
Department of Medicine, Division of General Internal Medicine, Brigham and Women s Hospital, Boston, MA, USA
Med Care 48:196-202. 2010..Although many patient, physician, and payment predictors of adherence have been described, knowledge of their relative strength and overall ability to explain adherence is limited... - Patterns of medication initiation in newly diagnosed diabetes mellitus: quality and cost implicationsNihar R Desai
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Am J Med 125:302.e1-7. 2012..We aimed to evaluate temporal trends in the use of specific drugs for the initial management of type 2 diabetes and to estimate the economic consequences of non-recommended care... - Modes of delivery for interventions to improve cardiovascular medication adherenceSarah L Cutrona
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Boston, MA, USA
Am J Manag Care 16:929-42. 2010..To determine the optimal modes of delivery for interventions to improve adherence to cardiovascular medications... - Comparative effectiveness of preventative therapy for venous thromboembolism after coronary artery bypass graft surgeryAlexander Kulik
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Circ Cardiovasc Interv 5:590-6. 2012..Controversy exists regarding the optimal preventative therapy for venous thromboembolism (VTE) after coronary artery bypass graft (CABG) surgery. We sought to compare the effectiveness and safety of the most commonly used regimens... - Healthcare information technology interventions to improve cardiovascular and diabetes medication adherenceAlexander S Misono
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Boston, MA 02120, USA
Am J Manag Care 16:SP82-92. 2010..To determine the efficacy of healthcare information technology (HIT) interventions in improving adherence... - Can improved prescription medication labeling influence adherence to chronic medications? An evaluation of the Target pharmacy labelWilliam H Shrank
Department of Medicine, Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street Suite 3030, Boston, MA 02120, USA
J Gen Intern Med 24:570-8. 2009..A new prescription medication labeling system was implemented by Target pharmacies in May 2005 and aimed to improve readability and understanding... - Warnings without guidance: patient responses to an FDA warning about ezetimibeWilliam H Shrank
Department of Medicine, Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston 02120, USA
Med Care 50:479-84. 2012..We investigated the proportion of patients who discontinued therapy and switched to a clinically appropriate alternative after the FDA communication... - Cost-effectiveness of genotype-guided warfarin dosing for patients with atrial fibrillationAmanda R Patrick
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Circ Cardiovasc Qual Outcomes 2:429-36. 2009..However, the effectiveness of genotyping in improving anticoagulation control and reducing major bleeding has not yet been compellingly demonstrated. Genotyping currently costs $400 to $550... - Rationale and design of the Study Assessing the Effect of Cardiovascular Medications Provided as Low-cost, Evidence-based Generic Samples (SAMPLES) trialWilliam H Shrank
Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Am Heart J 157:613-9. 2009..Highly effective generic cardiovascular medications are frequently underused, leading to greater overall drug costs and cost-related nonadherence... - The epidemiology of prescriptions abandoned at the pharmacyWilliam H Shrank
Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
Ann Intern Med 153:633-40. 2010..Understanding the epidemiology and correlates of prescription abandonment may have an important effect on health care quality... - Comparative cost-effectiveness of interventions to improve medication adherence after myocardial infarctionKouta Ito
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Health Serv Res 47:2097-117. 2012..To evaluate the comparative cost-effectiveness of interventions to improve adherence to evidence-based medications among postmyocardial infarction (MI) patients... - Targeting cardiovascular medication adherence interventionsSarah L Cutrona
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, USA
J Am Pharm Assoc (2003) 52:381-97. 2012..To determine whether adherence interventions should be administered to all medication takers or targeted to nonadherers... - Is there a relationship between patient beliefs or communication about generic drugs and medication utilization?William H Shrank
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Med Care 47:319-25. 2009..Insurers and policymakers strive to stimulate more cost-effective prescribing and, increasingly, are educating beneficiaries about generics... - A cohort study of thiazolidinediones and fractures in older adults with diabetesDaniel H Solomon
Division of Rheumatology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
J Clin Endocrinol Metab 94:2792-8. 2009..Recent results from several randomized controlled trials find an increased risk of fracture with TZDs compared with other oral antidiabetic agents... - The use of generic drugs in prevention of chronic disease is far more cost-effective than thought, and may save moneyWilliam H Shrank
CVS Caremark Harvard Partnership to Improve Medication Adherence, Brigham and Women s Hospital, Boston, MA, USA
Health Aff (Millwood) 30:1351-7. 2011..As the nation attempts to find strategies to improve population health without adding to the unsustainably high cost of care, policy makers should focus on ensuring that patients have access to essential generic medications... - Comparative efficacy and safety of new oral anticoagulants in patients with atrial fibrillationSebastian Schneeweiss
Department of Medicine, Harvard Medical School, Boston, MA, USA
Circ Cardiovasc Qual Outcomes 5:480-6. 2012..We sought to compare the efficacy and safety of the 3 new agents based on data from their published warfarin-controlled randomized trials, using the method of adjusted indirect comparisons... - Trouble getting started: predictors of primary medication nonadherenceMichael A Fischer
Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Am J Med 124:1081.e9-22. 2011..The advent of electronic prescribing (e-prescribing) systems provides the opportunity to track initial prescriptions and identify nonadherence that may have previously been undetected... - The consequences of requesting "dispense as written"William H Shrank
Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Am J Med 124:309-17. 2011..Patients also can make these requests. Little is known about the frequency and correlates of dispense as written requests or their association with medication filling... - Adherence to statin therapy in elderly patients after hospitalization for coronary revascularizationAlexander Kulik
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 107:1409-14. 2011..Given the health and economic consequences of nonadherence, these findings highlight the need for developing cost-effective strategies to improve medication adherence after coronary revascularization... - Physician effectiveness in interventions to improve cardiovascular medication adherence: a systematic reviewSarah L Cutrona
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Boston, MA 02120, USA
J Gen Intern Med 25:1090-6. 2010..Medications for the prevention and treatment of cardiovascular disease save lives but adherence is often inadequate. The optimal role for physicians in improving adherence remains unclear... - Are caregivers adherent to their own medications?William H Shrank
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
J Am Pharm Assoc (2003) 51:492-8. 2011..To explore caregiver adherence to chronic medications and predictors of appropriate medication use... - The impact of medication adherence on coronary artery disease costs and outcomes: a systematic reviewAsaf Bitton
Division of General Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
Am J Med 126:357.e7-357.e27. 2013..We sought to systematically review the literature on this topic area with a focus on quantified cost and clinical outcomes related to adherence... - Variations in pill appearance of antiepileptic drugs and the risk of nonadherenceAaron S Kesselheim
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
JAMA Intern Med 173:202-8. 2013..We sought to determine whether switching among different-appearing antiepileptic drugs (AEDs) is associated with increased rates of medication nonpersistence, which can have serious medical, financial, and social consequences... - A systematic review of adherence to cardiovascular medications in resource-limited settingsAshna D K Bowry
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
J Gen Intern Med 26:1479-91. 2011..To evaluate prevalence and predictors of non-adherence to cardiovascular medications in this context, we systematically reviewed the peer-reviewed literature... - Conflict of interest in oncology publications: a survey of disclosure policies and statementsAaron S Kesselheim
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Cancer 118:188-95. 2012..The authors sought to define current disclosure policies and how they relate to disclosure statements provided by authors in major oncology journals... - Variation in initiating secondary prevention after myocardial infarction by hospitals and physicians, 1997 through 2004Andrea V Margulis
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Pharmacoepidemiol Drug Saf 20:1088-97. 2011.... - Physician perceptions about generic drugsWilliam H Shrank
Brigham and Women s Hospital and Department of Medicine, Division of Pharmacoepidemiology and Pharmacoeconomics, Harvard Medical School, Boston, MA, USA
Ann Pharmacother 45:31-8. 2011..With constrained health-care resources, there is a need to understand barriers to cost-effective medication use... - Clinical equivalence of generic and brand-name drugs used in cardiovascular disease: a systematic review and meta-analysisAaron S Kesselheim
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
JAMA 300:2514-26. 2008..Use of generic drugs, which are bioequivalent to brand-name drugs, can help contain prescription drug spending. However, there is concern among patients and physicians that brand-name drugs may be clinically superior to generic drugs... - Meta-analysis of the efficacy and safety of clopidogrel plus aspirin as compared to antiplatelet monotherapy for the prevention of vascular eventsAshna D K Bowry
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Am J Cardiol 101:960-6. 2008.... - Cardiovascular outcomes and mortality in patients using clopidogrel with proton pump inhibitors after percutaneous coronary intervention or acute coronary syndromeJeremy A Rassen
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Boston, MA 02120, USA
Circulation 120:2322-9. 2009..Recent studies have raised concerns about the reduced efficacy of clopidogrel when used concurrently with proton pump inhibitors (PPIs), but those studies may have overestimated the risk... - An evaluation of the relationship between the implementation of a newly designed prescription drug label at Target pharmacies and health outcomesWilliam H Shrank
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Med Care 47:1031-5. 2009..A new prescription medication labeling system was implemented by Target pharmacies in May 2005 and aimed to improve health outcomes... - The international pharmaceutical market as a source of low-cost prescription drugs for U.S. patientsAaron S Kesselheim
Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Ann Intern Med 148:614-9. 2008.... - Impact of Medicaid prior authorization on angiotensin-receptor blockers: can policy promote rational prescribing?Michael A Fischer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital Harvard Medical School, Boston, Massachusetts, USA
Health Aff (Millwood) 26:800-7. 2007..3 percent per quarter; alternative approaches were unsuccessful. These findings have important implications for the development of rational drug reimbursement policy under Medicare Part D and other health insurance plans... - Trends in drug prescribing for osteoporosis after hip fracture, 1995-2004Suzanne M Cadarette
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
J Rheumatol 35:319-26. 2008..To examine trends in osteoporosis drug prescribing after hip fracture from 1995 to 2004... - Impact of statin use on outcomes after coronary artery bypass graft surgeryAlexander Kulik
Brigham and Women s Hospital, 1620 Tremont St, Suite 3030, Boston, MA 02120, USA
Circulation 118:1785-92. 2008.... - Gender and racial disparities in adherence to statin therapy: A meta-analysisJennifer Lewey
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA Department of Cardiology, Columbia University Medical Center, New York, NY
Am Heart J 165:665-678.e1. 2013..Our objective was to evaluate the effect of race/ethnicity and gender on adherence to statin therapy for primary or secondary prevention... - Preoperative statin use and postoperative acute kidney injurySteven M Brunelli
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
Am J Med 125:1195-1204.e3. 2012..The purpose of this study was to evaluate whether preoperative statin use is associated with a decreased risk of postoperative acute kidney injury... - Barriers to insulin progression among patients with type 2 diabetes: a systematic reviewJennifer M Polinski
Jennifer M Polinski, ScD, MPH, Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120
Diabetes Educ 39:53-65. 2013..Future studies should use multilevel longitudinal designs to quantify the relative impact of potential patient, provider, and health system factors on progression and health outcomes... - Statin utilization in nursing home patients after cardiac hospitalizationSeema Parikh
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
J Gen Intern Med 25:1293-9. 2010..Coronary artery disease (CAD) is highly prevalent in nursing home residents and is associated with a substantial clinical and economic burden. Statins reduce mortality and hospitalization rates in older patients with CAD... - Physicians' perceptions of relevant prescription drug costs: do costs to the individual patient or to the population matter most?William H Shrank
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Ste 3030, Boston, MA 02120, USA
Am J Manag Care 12:545-51. 2006..We evaluated physicians' perceptions about relevant costs for prescription drugs and the importance of communication about these costs... - The variability and quality of medication container labelsWilliam H Shrank
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont St, Ste 3030, Boston, MA 02120, USA
Arch Intern Med 167:1760-5. 2007..Medication errors occur frequently, and poor medication labeling is cited as a potential cause. We assessed the format, content, and variability of prescription drug container labels dispensed in the community... - A blueprint for pharmacy benefit managers to increase valueWilliam H Shrank
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 1620 Tremont St, Ste 3030, Boston, MA 02120, USA
Am J Manag Care 15:87-93. 2009..Incentives for PBMs to promote value should drive innovation and improve health outcomes... - Atrioventricular nodal ablation in atrial fibrillation: a meta-analysis and systematic reviewNeal A Chatterjee
Department of Medicine and the Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, MA 02411, USA
Circ Arrhythm Electrophysiol 5:68-76. 2012..Additionally, the impact of AVNA in patients with reduced systolic function is of growing interest... - Online social networking by patients with diabetes: a qualitative evaluation of communication with FacebookJeremy A Greene
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
J Gen Intern Med 26:287-92. 2011..These new sources of knowledge, support, and engagement have become important for patients living with chronic disease, yet the quality and content of the information provided in these digital arenas are poorly understood... - Systematic review: the relationship between clinical experience and quality of health careNiteesh K Choudhry
Harvard Medical School and Harvard Pilgrim Health Care, Brigham and Women s Hospital, Boston, Massachusetts, USA
Ann Intern Med 142:260-73. 2005..However, evidence suggests that there is an inverse relationship between the number of years that a physician has been in practice and the quality of care that the physician provides... - Over-the-counter statinsNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts 02120, USA
Ann Intern Med 142:910-3. 2005..quot;.. - Patients' perceptions of generic medicationsWilliam H Shrank
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, at Brigham and Women s Hospital Harvard Medical School in Boston, Massachusetts, USA
Health Aff (Millwood) 28:546-56. 2009..These findings underscore the challenge that providers, insurers, and policymakers face in stimulating the cost-effective use of medications... - Effect of the Women's Health Initiative on osteoporosis therapy and expenditure in MedicaidJacob A Udell
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02120, USA
J Bone Miner Res 21:765-71. 2006..Determining whether these trends are clinically appropriate and cost effective for osteoporosis therapy will have important implications for the development of future drug reimbursement programs, especially for elderly patients... - Pulmonary vein isolation with complex fractionated atrial electrogram ablation for paroxysmal and nonparoxysmal atrial fibrillation: A meta-analysisRobert M Hayward
Department of Medicine and Cardiac Arrhythmia Service, Massachusetts General Hospital Heart Center, Boston, Massachusetts, USA
Heart Rhythm 8:994-1000. 2011..Ablation of complex fractionated atrial electrograms (CFAEs) in addition to PVI has been advocated as a means to improve procedural outcomes, but the benefit remains unclear... - How should patients with unstable angina and non-ST-segment elevation myocardial infarction be managed? A meta-analysis of randomized trialsNiteesh K Choudhry
Harvard Medical School and Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
Am J Med 118:465-74. 2005..Patients with unstable angina or non-ST-segment elevation myocardial infarction (MI) may be managed with either an "invasive" or "conservative" strategy. It is unclear which of these strategies is superior... - Cardiac resynchronization in patients with atrial fibrillation: a meta-analysis of prospective cohort studiesGaurav A Upadhyay
Department of Medicine and the Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Am Coll Cardiol 52:1239-46. 2008..This study is a meta-analysis of prospective cohort studies comparing the impact of cardiac resynchronization therapy (CRT) for patients in atrial fibrillation (AF) and sinus rhythm (SR)... - Early angiography in patients with chronic kidney disease: a collaborative systematic reviewDavid M Charytan
Renal Division and Clinical Biometrics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Clin J Am Soc Nephrol 4:1032-43. 2009.... - Does this patient with a pericardial effusion have cardiac tamponade?Christopher L Roy
Division of General Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
JAMA 297:1810-8. 2007..The clinical examination may assist in the decision to perform pericardiocentesis in patients with cardiac tamponade diagnosed by echocardiography... - A perspective on US drug reimportationNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass 02120, USA
JAMA 293:358-62. 2005 - CPR for patients labeled DNR: the role of the limited aggressive therapy orderNiteesh K Choudhry
Harvard University, Cambridge, Massachusetts, USA
Ann Intern Med 138:65-8. 2003..This new level of resuscitation could be called a "limited aggressive therapy" order... - A perspective on U.S. drug reimportationNiteesh K Choudhry
Brigham and Women's Hospital
Minn Med 88:46-51. 2005 - Primary prevention of cardiovascular diseases with statin therapy: a meta-analysis of randomized controlled trialsPaaladinesh Thavendiranathan
Department of Medicine, University of Toronto, Toronto, Ontario
Arch Intern Med 166:2307-13. 2006..CONCLUSION: In patients without CV disease, statin therapy decreases the incidence of major coronary and cerebrovascular events and revascularizations but not coronary heart disease or overall mortality... - Patterns and predictors of statin use after coronary artery bypass graft surgeryAlexander Kulik
Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Canada
J Thorac Cardiovasc Surg 134:932-8. 2007..The purposes of this study were to assess statin prescription rates in patients who have undergone coronary artery bypass graft surgery and to identify the determinants of postoperative statin administration... - Medication adherence after myocardial infarction: a long way left to goNiteesh K Choudhry
J Gen Intern Med 23:216-8. 2008 - Ventricular arrhythmias and cerebrovascular events in the elderly using conventional and atypical antipsychotic medicationsPhilip S Wang
J Clin Psychopharmacol 27:707-10. 2007 - Do blood tests cause anemia in hospitalized patients? The effect of diagnostic phlebotomy on hemoglobin and hematocrit levelsPaaladinesh Thavendiranathan
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
J Gen Intern Med 20:520-4. 2005..To determine whether phlebotomy contributes to changes in hemoglobin and hematocrit levels in hospitalized general internal medicine patients... - Physician responses to the malpractice crisis: from defense to offenseAllen Kachalia
Division of General Medicine, Brigham and Women's Hospital, USA
J Law Med Ethics 33:416-28. 2005 - Using computer-based decision support to close the "know do" gap in lipid-lowering therapyJerry Avorn
Circulation 117:336-7. 2008