Zhe Chen

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. ncbi Transductive neural decoding for unsorted neuronal spikes of rat hippocampus
    Zhe Chen
    Department of Brain and Cognitive Sciences, MIT, Cambridge, MA 02139, USA
    Conf Proc IEEE Eng Med Biol Soc 2012:1310-3. 2012
  2. ncbi Uncovering spatial topology represented by rat hippocampal population neuronal codes
    Zhe Chen
    Neuroscience Statistics Research Lab, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Comput Neurosci 33:227-55. 2012
  3. ncbi Assessing neuronal interactions of cell assemblies during general anesthesia
    Zhe Chen
    Department of Brain and Cognitive Sciences, MIT, Cambridge, MA 02139, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:4175-8. 2011
  4. ncbi A differential autoregressive modeling approach within a point process framework for non-stationary heartbeat intervals analysis
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Conf Proc IEEE Eng Med Biol Soc 2010:3567-70. 2010
  5. ncbi Dynamic assessment of baroreflex control of heart rate during induction of propofol anesthesia using a point process method
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Ann Biomed Eng 39:260-76. 2011
  6. ncbi A regularized point process generalized linear model for assessing the functional connectivity in the cat motor cortex
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:5006-9. 2009
  7. ncbi Discrete- and continuous-time probabilistic models and algorithms for inferring neuronal UP and DOWN states
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Neural Comput 21:1797-862. 2009
  8. ncbi Statistical inference for assessing functional connectivity of neuronal ensembles with sparse spiking data
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, 02114, USA
    IEEE Trans Neural Syst Rehabil Eng 19:121-35. 2011
  9. ncbi Motor cortical networks for skilled movements have dynamic properties that are related to accurate reaching
    David F Putrino
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Neural Plast 2011:413543. 2011
  10. ncbi Linear and nonlinear quantification of respiratory sinus arrhythmia during propofol general anesthesia
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:5336-9. 2009

Detail Information

Publications20

  1. ncbi Transductive neural decoding for unsorted neuronal spikes of rat hippocampus
    Zhe Chen
    Department of Brain and Cognitive Sciences, MIT, Cambridge, MA 02139, USA
    Conf Proc IEEE Eng Med Biol Soc 2012:1310-3. 2012
    ..Here, we investigate several important technical issues of this new paradigm using one data set of one animal. Several extensions of our decoding method are discussed...
  2. ncbi Uncovering spatial topology represented by rat hippocampal population neuronal codes
    Zhe Chen
    Neuroscience Statistics Research Lab, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Comput Neurosci 33:227-55. 2012
    ..This study would also provide useful insights for future exploratory data analysis of population neuronal codes during periods of sleep...
  3. ncbi Assessing neuronal interactions of cell assemblies during general anesthesia
    Zhe Chen
    Department of Brain and Cognitive Sciences, MIT, Cambridge, MA 02139, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:4175-8. 2011
    ..Our results suggest that that neuronal interactions of both putative excitatory and inhibitory connections are reduced after the induction of isoflurane anesthesia...
  4. ncbi A differential autoregressive modeling approach within a point process framework for non-stationary heartbeat intervals analysis
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Conf Proc IEEE Eng Med Biol Soc 2010:3567-70. 2010
    ..Results further demonstrate the ability of the method to appropriately quantify the non-stationary evolution of baroreflex sensitivity in changing physiological and pharmacological conditions...
  5. ncbi Dynamic assessment of baroreflex control of heart rate during induction of propofol anesthesia using a point process method
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Ann Biomed Eng 39:260-76. 2011
    ....
  6. ncbi A regularized point process generalized linear model for assessing the functional connectivity in the cat motor cortex
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:5006-9. 2009
    ..The point process model was applied to an ensemble of neurons recorded from the cat motor cortex during a skilled reaching task. The implications of this analysis to the coding of skilled movement in primary motor cortex is discussed...
  7. ncbi Discrete- and continuous-time probabilistic models and algorithms for inferring neuronal UP and DOWN states
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Neural Comput 21:1797-862. 2009
    ..Our approach provides a statistical characterization of UP-DOWN state dynamics that can serve as a basis for verifying and refining mechanistic descriptions of this process...
  8. ncbi Statistical inference for assessing functional connectivity of neuronal ensembles with sparse spiking data
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, 02114, USA
    IEEE Trans Neural Syst Rehabil Eng 19:121-35. 2011
    ..The identification of spiking dependencies in physiologically acquired data was encouraging, since their sparse nature would have previously precluded them from successful analysis using traditional methods...
  9. ncbi Motor cortical networks for skilled movements have dynamic properties that are related to accurate reaching
    David F Putrino
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Neural Plast 2011:413543. 2011
    ..The results of this study indicate that reach-related neurons in MI form dynamic spiking dependencies whose temporal features are highly sensitive to unforced movement errors...
  10. ncbi Linear and nonlinear quantification of respiratory sinus arrhythmia during propofol general anesthesia
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:5336-9. 2009
    ..Our proposed statistical indices provide a valuable quantitative assessment of instantaneous cardiorespiratory control and heart rate variability (HRV) during general anesthesia...
  11. ncbi Characterizing nonlinear heartbeat dynamics within a point process framework
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
    IEEE Trans Biomed Eng 57:1335-47. 2010
    ..In comparison to other nonlinear modeling approaches, the point process probability model is useful in revealing nonlinear heartbeat dynamics at a fine timescale and with only short duration recordings...
  12. ncbi Assessment of hippocampal and autonomic neural activity by point process models
    Riccardo Barbieri
    Neuroscience Statistics Research Laboratory, Dept of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Conf Proc IEEE Eng Med Biol Soc 2008:3679. 2008
    ..The first studies how hippocampal neural activity represents and transmits information, whereas the second is aimed at characterizing activity of the central autonomic network as involved in cardiovascular control...
  13. ncbi Characterizing nonlinear heartbeat dynamics within a point process framework
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Conf Proc IEEE Eng Med Biol Soc 2008:2781-4. 2008
    ..The proposed probabilistic model was examined with two recorded heartbeat interval data sets. Preliminary results show that our model is beneficial to characterize the inherent nonlinearity of the heartbeat dynamics...
  14. ncbi Instantaneous assessment of autonomic cardiovascular control during general anesthesia
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:8444-7. 2011
    ....
  15. ncbi A probabilistic framework for learning robust common spatial patterns
    Wei Wu
    Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:4658-61. 2009
    ..The efficacy of the proposed robust algorithm is validated with both simulated and real EEG data...
  16. ncbi A hierarchical Bayesian approach for learning sparse spatio-temporal decompositions of multichannel EEG
    Wei Wu
    Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Neuroimage 56:1929-45. 2011
    ....
  17. ncbi Assessment of autonomic control and respiratory sinus arrhythmia using point process models of human heart beat dynamics
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    IEEE Trans Biomed Eng 56:1791-802. 2009
    ..Our paradigm suggests a possible framework for designing a device for ambulatory monitoring and assessment of autonomic control in both laboratory research and clinical practice...
  18. ncbi A unified point process probabilistic framework to assess heartbeat dynamics and autonomic cardiovascular control
    Zhe Chen
    Neuroscience Statistics Research Lab, Massachusetts General Hospital, Harvard Medical School Boston, MA, USA
    Front Physiol 3:4. 2012
    ..We also discuss the limitations and other alternative modeling strategies of our point process approach...
  19. ncbi Mapping of visual receptive fields by tomographic reconstruction
    Gordon Pipa
    Neuroscience Statistics Research Lab, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Neural Comput 24:2543-78. 2012
    ....
  20. ncbi An empirical quantitative EEG analysis for evaluating clinical brain death
    Zhe Chen
    Neuroscience Statistics Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Conf Proc IEEE Eng Med Biol Soc 2007:3880-3. 2007
    ..The empirical results reported in this paper suggest some promising directions and valuable clues for clinical practice...