Lucy Chen

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Lack of correlation between opioid dose adjustment and pain score change in a group of chronic pain patients
    Lucy Chen
    Massachusetts General Hospital Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Pain 14:384-92. 2013
  2. doi request reprint A survey of selected physician views on acupuncture in pain management
    Lucy Chen
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Pain Med 11:530-4. 2010
  3. pmc A functional relationship between trigeminal astroglial activation and NR1 expression in a rat model of temporomandibular joint inflammation
    Shuxing Wang
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Pain Med 13:1590-600. 2012
  4. pmc Disruption of persistent nociceptive behavior in rats with learning impairment
    Yuxin Ma
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America Department of Anatomy, School of Basic Medicine, Guangdong Pharmaceutical University, Guangzhou, Guangdong, China Department of Anatomy, Zhongshan School of Medicine, Sun Yat Sen University, Guangzhou, China
    PLoS ONE 8:e74533. 2013
  5. pmc Spinal expression of Hippo signaling components YAP and TAZ following peripheral nerve injury in rats
    Na Li
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA Department of Anesthesiology, Kunming General Hospital of Chengdu Military Command, Kunming, Yunnan, China Electronic address
    Brain Res 1535:137-47. 2013
  6. ncbi request reprint Opioid therapy for chronic pain: physicians' attitude and current practice patterns
    Lucy Chen
    Center for Translational Pain Research, Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Opioid Manag 7:267-76. 2011
  7. pmc Exacerbated mechanical hyperalgesia in rats with genetically predisposed depressive behavior: role of melatonin and NMDA receptors
    Shuxing Wang
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Pain 153:2448-57. 2012
  8. pmc Altered quantitative sensory testing outcome in subjects with opioid therapy
    Lucy Chen
    MGH Center for Translational Pain Research, Department of Anesthesia and Critical Care, WACC 324, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Pain 143:65-70. 2009
  9. pmc Nociceptive behavior following hindpaw burn injury in young rats: response to systemic morphine
    Shuxing Wang
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Pain Med 12:87-98. 2011
  10. pmc Midazolam exacerbates morphine tolerance and morphine-induced hyperactive behaviors in young rats with burn injury
    Li Song
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA Department of Anesthesia, West China Hospital, Sichuan University, Chengdu, China
    Brain Res 1564:52-61. 2014

Collaborators

  • Yi Zhang
  • Na Li
  • Lin Zhang
  • Backil Sung
  • Shuxing Wang
  • Jianren Mao
  • Yinghong Tian
  • Li Song
  • Yuxin Ma
  • Grewo Lim
  • Kelly Yan Chen
  • Yonghui Tan
  • Hyangin Kim
  • Jeevendra A Martyn
  • Yunxia Zuo
  • Guoying Li
  • Michael F McCabe
  • Gabriel Rusanescu
  • Liling Yang
  • Shuzhuo Zhang
  • Xu Jin
  • Zerong You
  • Jeevendra J A Martyn

Detail Information

Publications13

  1. pmc Lack of correlation between opioid dose adjustment and pain score change in a group of chronic pain patients
    Lucy Chen
    Massachusetts General Hospital Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Pain 14:384-92. 2013
    ....
  2. doi request reprint A survey of selected physician views on acupuncture in pain management
    Lucy Chen
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Pain Med 11:530-4. 2010
    ..To collect information on the role of acupuncture in pain management from pain physicians and referral physicians who manage clinical pain conditions...
  3. pmc A functional relationship between trigeminal astroglial activation and NR1 expression in a rat model of temporomandibular joint inflammation
    Shuxing Wang
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Pain Med 13:1590-600. 2012
    ..To examine the hypothesis that glial activation would regulate the expression of the N-methyl-D-aspartate receptor subunit 1 (NR1) in the trigeminal subnucleus caudalis (Sp5C) after temporomandibular joint (TMJ) inflammation...
  4. pmc Disruption of persistent nociceptive behavior in rats with learning impairment
    Yuxin Ma
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America Department of Anatomy, School of Basic Medicine, Guangdong Pharmaceutical University, Guangzhou, Guangdong, China Department of Anatomy, Zhongshan School of Medicine, Sun Yat Sen University, Guangzhou, China
    PLoS ONE 8:e74533. 2013
    ..These results also suggest that a preclinical model of combined learning impairment and persistent nociception may be useful to explore the brain mechanisms underlying the transition from acute to chronic pain. ..
  5. pmc Spinal expression of Hippo signaling components YAP and TAZ following peripheral nerve injury in rats
    Na Li
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA Department of Anesthesiology, Kunming General Hospital of Chengdu Military Command, Kunming, Yunnan, China Electronic address
    Brain Res 1535:137-47. 2013
    ..A role for Hippo signaling in synaptic and structural plasticity is discussed in relation to the cellular mechanism of neuropathic pain. ..
  6. ncbi request reprint Opioid therapy for chronic pain: physicians' attitude and current practice patterns
    Lucy Chen
    Center for Translational Pain Research, Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Opioid Manag 7:267-76. 2011
    ....
  7. pmc Exacerbated mechanical hyperalgesia in rats with genetically predisposed depressive behavior: role of melatonin and NMDA receptors
    Shuxing Wang
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Pain 153:2448-57. 2012
    ....
  8. pmc Altered quantitative sensory testing outcome in subjects with opioid therapy
    Lucy Chen
    MGH Center for Translational Pain Research, Department of Anesthesia and Critical Care, WACC 324, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Pain 143:65-70. 2009
    ..The data suggest that QST may be a useful tool in the clinical assessment of OIH...
  9. pmc Nociceptive behavior following hindpaw burn injury in young rats: response to systemic morphine
    Shuxing Wang
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Pain Med 12:87-98. 2011
    ..Develop a burn injury model in young age rats...
  10. pmc Midazolam exacerbates morphine tolerance and morphine-induced hyperactive behaviors in young rats with burn injury
    Li Song
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA Department of Anesthesia, West China Hospital, Sichuan University, Chengdu, China
    Brain Res 1564:52-61. 2014
    ..These results indicate that midazolam exacerbated morphine tolerance through a spinal NMDA/PKC-mediated mechanism. ..
  11. pmc Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression
    Hyangin Kim
    MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Clin Invest 122:2940-54. 2012
    ..These results reveal an IDO1-mediated regulatory mechanism underlying the comorbidity of pain and depression and suggest a new strategy for the concurrent treatment of both conditions via modulation of brain IDO1 activity...
  12. pmc Buprenorphine-naloxone therapy in pain management
    Kelly Yan Chen
    From the Albert Einstein College of Medicine, Yeshiva University, Bronx, New York K Y C and MGH Center for Translational Pain Research, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts L C, J M
    Anesthesiology 120:1262-74. 2014
    ..Additional studies are needed to assess the implication of bup/nal therapy in clinical anesthesia and perioperative pain management. ..
  13. doi request reprint Update on neuropathic pain treatment: ion channel blockers and gabapentinoids
    Lucy Chen
    Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Curr Pain Headache Rep 17:359. 2013
    ..This article provides several updates on the utility of both ion channel blockers and gabapentinoids for the treatment of neuropathic pain. ..

Research Grants2

  1. A Method for Evaluating Acupuncture Therapy in Pain Management
    Lucy Chen; Fiscal Year: 2009
    ..This new approach could be used to compare the therapeutic effects on clinical pain between acupuncture (other forms of alternative medicine as well) and conventional medicine. ..
  2. A Method for Evaluating Acupuncture Therapy in Pain Management
    Lucy L Chen; Fiscal Year: 2010
    ..This new approach could be used to compare the therapeutic effects on clinical pain between acupuncture (other forms of alternative medicine as well) and conventional medicine. ..