Yuchiao Chang

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint The effect of surgical and nonsurgical treatment on longitudinal outcomes of lumbar spinal stenosis over 10 years
    Yuchiao Chang
    General Medicine Division and the Clinical Epidemiology Unit, Medical Services, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Am Geriatr Soc 53:785-92. 2005
  2. pmc CT angiography predicts use of tertiary interventional services in acute ischemic stroke patients
    Lisa E Thomas
    Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA
    Int J Emerg Med 4:62. 2011
  3. pmc Predicting post-trauma stress symptoms from pre-trauma psychophysiologic reactivity, personality traits and measures of psychopathology
    Scott P Orr
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA
    Biol Mood Anxiety Disord 2:8. 2012
  4. pmc Decision quality instrument for treatment of hip and knee osteoarthritis: a psychometric evaluation
    Karen R Sepucha
    General Medicine Division, Massachusetts General Hospital MGH, Harvard Medical School HMS, Boston, MA, USA
    BMC Musculoskelet Disord 12:149. 2011
  5. pmc Food assistance is associated with improved body mass index, food security and attendance at clinic in an HIV program in central Haiti: a prospective observational cohort study
    Louise C Ivers
    Division of Global Health Equity, Brigham and Women s Hospital, Boston, Massachusetts, USA
    AIDS Res Ther 7:33. 2010
  6. doi request reprint "Blush" on trauma computed tomography: not as bad as we think!
    Maria Michailidou
    Division of Trauma, Emergency Surgery, and Surgical Critical Care and the Department of Biostatistics and Epidemiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Trauma Acute Care Surg 73:580-4; discussion 584-6. 2012
  7. doi request reprint An empirical assessment of boarding and quality of care: delays in care among chest pain, pneumonia, and cellulitis patients
    Shan W Liu
    Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    Acad Emerg Med 18:1339-48. 2011
  8. pmc Should patient characteristics influence target anticoagulation intensity for stroke prevention in nonvalvular atrial fibrillation?: the ATRIA study
    Daniel E Singer
    Clinical Epidemiology Unit, General Medicine Division, Massachusetts General Hospital, Boston, MA 02114, USA
    Circ Cardiovasc Qual Outcomes 2:297-304. 2009
  9. pmc Comparative effectiveness of post-discharge interventions for hospitalized smokers: study protocol for a randomized controlled trial
    Sandra J Japuntich
    Tobacco Research and Treatment Center, Massachusetts General Hospital, Boston, USA
    Trials 13:124. 2012
  10. doi request reprint Randomized controlled trial of a video decision support tool for cardiopulmonary resuscitation decision making in advanced cancer
    Angelo E Volandes
    Massachusetts General Hospital, General Medicine Unit, 50 Staniford St, 9th Floor, Boston, MA 02114, USA
    J Clin Oncol 31:380-6. 2013

Detail Information

Publications122 found, 100 shown here

  1. ncbi request reprint The effect of surgical and nonsurgical treatment on longitudinal outcomes of lumbar spinal stenosis over 10 years
    Yuchiao Chang
    General Medicine Division and the Clinical Epidemiology Unit, Medical Services, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Am Geriatr Soc 53:785-92. 2005
    ..To assess the relative effect of initial surgical and nonsurgical treatment on longitudinal outcomes of patients with lumbar spinal stenosis over a 10-year follow-up period...
  2. pmc CT angiography predicts use of tertiary interventional services in acute ischemic stroke patients
    Lisa E Thomas
    Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA
    Int J Emerg Med 4:62. 2011
    ..abstract:..
  3. pmc Predicting post-trauma stress symptoms from pre-trauma psychophysiologic reactivity, personality traits and measures of psychopathology
    Scott P Orr
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA
    Biol Mood Anxiety Disord 2:8. 2012
    ..abstract:..
  4. pmc Decision quality instrument for treatment of hip and knee osteoarthritis: a psychometric evaluation
    Karen R Sepucha
    General Medicine Division, Massachusetts General Hospital MGH, Harvard Medical School HMS, Boston, MA, USA
    BMC Musculoskelet Disord 12:149. 2011
    ..The aim of this study was to evaluate the psychometric properties and clinical sensibility of a patient self report instrument, to measure the quality of decisions about total joint replacement for knee or hip osteoarthritis...
  5. pmc Food assistance is associated with improved body mass index, food security and attendance at clinic in an HIV program in central Haiti: a prospective observational cohort study
    Louise C Ivers
    Division of Global Health Equity, Brigham and Women s Hospital, Boston, Massachusetts, USA
    AIDS Res Ther 7:33. 2010
    ..We evaluated the impact of food assistance on patient outcomes in a comprehensive HIV program in central Haiti in a prospective observational cohort study...
  6. doi request reprint "Blush" on trauma computed tomography: not as bad as we think!
    Maria Michailidou
    Division of Trauma, Emergency Surgery, and Surgical Critical Care and the Department of Biostatistics and Epidemiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Trauma Acute Care Surg 73:580-4; discussion 584-6. 2012
    ..The new-generation computed tomographic (CT) scanners identify IVCE with increasing frequency. We hypothesized that most IVCEs do not require an intervention...
  7. doi request reprint An empirical assessment of boarding and quality of care: delays in care among chest pain, pneumonia, and cellulitis patients
    Shan W Liu
    Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    Acad Emerg Med 18:1339-48. 2011
    ..To the best of our knowledge, no study has compared the quality of care of boarded and nonboarded patients...
  8. pmc Should patient characteristics influence target anticoagulation intensity for stroke prevention in nonvalvular atrial fibrillation?: the ATRIA study
    Daniel E Singer
    Clinical Epidemiology Unit, General Medicine Division, Massachusetts General Hospital, Boston, MA 02114, USA
    Circ Cardiovasc Qual Outcomes 2:297-304. 2009
    ..0 to 3.0 for preventing ischemic stroke in atrial fibrillation. We assessed whether the INR target should be adjusted based on selected patient characteristics...
  9. pmc Comparative effectiveness of post-discharge interventions for hospitalized smokers: study protocol for a randomized controlled trial
    Sandra J Japuntich
    Tobacco Research and Treatment Center, Massachusetts General Hospital, Boston, USA
    Trials 13:124. 2012
    ..This paper describes the design of a comparative effectiveness trial testing a hospital-initiated intervention against standard care...
  10. doi request reprint Randomized controlled trial of a video decision support tool for cardiopulmonary resuscitation decision making in advanced cancer
    Angelo E Volandes
    Massachusetts General Hospital, General Medicine Unit, 50 Staniford St, 9th Floor, Boston, MA 02114, USA
    J Clin Oncol 31:380-6. 2013
    ..Decision making regarding cardiopulmonary resuscitation (CPR) is challenging. This study examined the effect of a video decision support tool on CPR preferences among patients with advanced cancer...
  11. doi request reprint Risk of thromboembolism following acute intracerebral hemorrhage
    Joshua N Goldstein
    Department of Emergency Medicine, Massachusetts General Hospital, Zero Emerson Place, Suite 3B, Boston, MA 02114, USA
    Neurocrit Care 10:28-34. 2009
    ..We hypothesized that TEs are relatively common following ICH, and that anticoagulated patients are at higher risk for these complications...
  12. doi request reprint Blunt pulmonary contusion: admission computed tomography scan predicts mechanical ventilation
    Marc A de Moya
    Division of Trauma Emergency Surgery and Surgical Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    J Trauma 71:1543-7. 2011
    ..Admission computed tomography (CT) may offer accurate characterization of BPC and early prediction of the need for mechanical ventilation (MV)...
  13. doi request reprint Vitamin D therapy and cardiac structure and function in patients with chronic kidney disease: the PRIMO randomized controlled trial
    Ravi Thadhani
    Division of Nephrology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    JAMA 307:674-84. 2012
    ..Vitamin D is associated with decreased cardiovascular-related morbidity and mortality, possibly by modifying cardiac structure and function, yet firm evidence for either remains lacking...
  14. ncbi request reprint Recruiting pregnant smokers into a clinical trial: using a network-model managed care organization versus community-based practices
    Elyse R Park
    Massachusetts General Hospital Harvard Medical School, Boston, MA 02114, USA
    Prev Med 44:223-9. 2007
    ..This paper reports the results of utilizing this novel approach and compares it with a typical decentralized practice-based recruitment strategy...
  15. doi request reprint Candida infection and colonization among trauma patients
    Dimitra Manolakaki
    Division of Trauma Emergency Surgery and Surgical Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Virulence 1:367-75. 2010
    ..Data on Candida infection among critically ill trauma patients are limited and not recently updated. Here we study the epidemiology and economic impact of Candida and examine potential risk factors for Candida infection in this population...
  16. doi request reprint Implementation of 24/7 intensivist presence in the SICU: effect on processes of care
    Gwendolyn M van der Wilden
    Division of Trauma, Emergency Surgery, and Surgical Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02141, USA
    J Trauma Acute Care Surg 74:563-7. 2013
    ..We hypothesized that 24/7 attending intensivist staffing in the SICU would improve outcomes and processes of care...
  17. doi request reprint Vitamin D reduces left atrial volume in patients with left ventricular hypertrophy and chronic kidney disease
    Hector Tamez
    Department of Medicine, Division of Nephrology, Massachusetts General Hospital, Boston, USA
    Am Heart J 164:902-9.e2. 2012
    ..We assessed the effect of an activated vitamin D analog on left atrial volume index (LAVi) in a post hoc analysis of the PRIMO trial (clinicaltrials.gov: NCT00497146)...
  18. doi request reprint Effect of medical or surgical admission on outcome of patients with gallstone pancreatitis and common bile duct stones
    Jennifer LaFemina
    Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    J Gastrointest Surg 12:1554-60. 2008
    ..This study evaluates the impact of admitting team on outcome and cost...
  19. doi request reprint Predictors of bleeding from stable pelvic fractures
    Athanasios Bramos
    Division of Trauma, Emergency Surgery, and Surgical Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Arch Surg 146:407-11. 2011
    ..Our hypothesis is that simple indicators, easily detectable at the bedside, can alert the clinician about the likelihood of bleeding and the need for closer monitoring or early intervention in patients with SPFs...
  20. pmc Augmenting communication and decision making in the intensive care unit with a cardiopulmonary resuscitation video decision support tool: a temporal intervention study
    Jessica B McCannon
    Harvard Medical School, Boston, Massachusetts, USA
    J Palliat Med 15:1382-7. 2012
    ....
  21. pmc Prolonged emergency department length of stay is not associated with worse outcomes in patients with intracerebral hemorrhage
    Jonathan Elmer
    Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA
    Neurocrit Care 17:334-42. 2012
    ..We performed this study to explore the hypothesis that longer EDLOS would be associated with worse outcomes in a large cohort of patients presenting with spontaneous intracerebral hemorrhage (ICH)...
  22. doi request reprint Defining patient complexity from the primary care physician's perspective: a cohort study
    Richard W Grant
    Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Ann Intern Med 155:797-804. 2011
    ..Patients with complex health needs are increasingly the focus of health system redesign...
  23. doi request reprint A randomized controlled trial of adding the nicotine patch to rimonabant for smoking cessation: efficacy, safety and weight gain
    Nancy A Rigotti
    Tobacco Research and Treatment Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Addiction 104:266-76. 2009
    ....
  24. pmc The association of depressive, anxiety, and stress symptoms and postpartum relapse to smoking: a longitudinal study
    Elyse R Park
    Tobacco Research and Treatment Center, Institute for Health Policy, and Department of Psychiatry, Massachusetts General Hospital, 50 Staniford Street, 9th Floor, Boston, MA 02114, USA
    Nicotine Tob Res 11:707-14. 2009
    ..The aim of this prospective repeated measures, mixed-methods observational study was to assess whether depressive, anxiety, and stress symptoms are associated with postpartum relapse to smoking...
  25. ncbi request reprint Functional recovery following rehabilitation after hemorrhagic and ischemic stroke
    Peter J Kelly
    Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Boston, MA 02114, USA
    Arch Phys Med Rehabil 84:968-72. 2003
    ..To quantify recovery after rehabilitation therapy and to identify factors that predicted functional outcome in survivors of intracerebral hemorrhage (ICH) compared with cerebral infarction...
  26. doi request reprint Boarding inpatients in the emergency department increases discharged patient length of stay
    Benjamin A White
    Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Emerg Med 44:230-5. 2013
    ..We hypothesize that these deleterious effects extend to those patients who are discharged from the ED by increasing their length of stay (LOS)...
  27. doi request reprint Impact of physician-assisted triage on timing of antibiotic delivery in patients admitted to the hospital with community-acquired pneumonia (CAP)
    Roberta Capp
    Harvard Affiliated Emergency Medicine Residency, Brigham and Women s Hospital and Massachusetts General Hospital, Boston, MA 02115, USA
    J Emerg Med 43:502-8. 2012
    ..Time to antibiotic delivery in patients with diagnosis of pneumonia is a publicly reported quality measure...
  28. pmc Implementation of a parental tobacco control intervention in pediatric practice
    Jonathan P Winickoff
    Center for Child and Adolescent Health Research and Policy, Massachusetts General Hospital, Boston, MA 02114, USA
    Pediatrics 132:109-17. 2013
    ..To test whether routine pediatric outpatient practice can be transformed to assist parents in quitting smoking...
  29. doi request reprint Intraparenchymal vs extracranial ventricular drain intracranial pressure monitors in traumatic brain injury: less is more?
    George Kasotakis
    Division of Trauma, Emergency Surgery and Surgical Critical Care, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Am Coll Surg 214:950-7. 2012
    ..Our hypothesis was that neurologic outcomes are unaffected by the type of ICP monitoring device...
  30. pmc A randomized controlled trial of a goals-of-care video for elderly patients admitted to skilled nursing facilities
    Angelo E Volandes
    Harvard Medical School, Boston, MA 02114, USA
    J Palliat Med 15:805-11. 2012
    ..Options included: life-prolonging (i.e., cardiopulmonary resuscitation), limited (i.e., hospitalization but no cardiopulmonary resuscitation), or comfort care (i.e., symptom relief)...
  31. doi request reprint Improving decision making at the end of life with video images
    Angelo E Volandes
    Harvard Medical School, Boston, Massachusetts, USA
    Med Decis Making 30:29-34. 2010
    ..We hypothesized that people with limited health literacy would have more uncertainty about end-of-life decision making than people with adequate literacy. We also hypothesized that video images would decrease uncertainty...
  32. doi request reprint Fulminant Clostridium difficile colitis: patterns of care and predictors of mortality
    Elizabeth A Sailhamer
    Department of Surgery, Division of Trauma, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Arch Surg 144:433-9; discussion 439-40. 2009
    ..There exist predictors of mortality and the need for colectomy among patients with fulminant Clostridium difficile colitis...
  33. pmc Patient-physician connectedness and quality of primary care
    Steven J Atlas
    Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Ann Intern Med 150:325-35. 2009
    ..Among all patients seen by a physician, some will be more strongly connected to their physician than others, but the effect of connectedness on measures of physician performance is not known...
  34. pmc Using video images to improve the accuracy of surrogate decision-making: a randomized controlled trial
    Angelo E Volandes
    General Medicine Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    J Am Med Dir Assoc 10:575-80. 2009
    ..Unfortunately, multiple studies have shown that surrogates' knowledge of patient preferences is poor. We hypothesized that a video decision tool would improve concordance between patients and their surrogates for end-of-life preferences...
  35. pmc The net clinical benefit of warfarin anticoagulation in atrial fibrillation
    Daniel E Singer
    Massachusetts General Hospital, Boston, Massachussetts 02114, USA
    Ann Intern Med 151:297-305. 2009
    ..These guidelines rely on ischemic stroke rates observed in older trials and do not explicitly account for increased risk for hemorrhage...
  36. doi request reprint Smoking cessation medication use among pregnant and postpartum smokers
    Nancy A Rigotti
    Tobacco Research and Treatment Center, Department of Medicine, and Institute for Health Policy, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Obstet Gynecol 111:348-55. 2008
    ..To assess how often pregnant and postpartum smokers use medications and how often obstetric providers recommend them...
  37. doi request reprint Presenting blood pressure in traumatic brain injury: a bimodal distribution of death
    Syed Nabeel Zafar
    Harvard School of Public Health, Boston Massachusetts, USA
    J Trauma 71:1179-84. 2011
    ..This work has not included traumatic brain injury (TBI). We aimed to evaluate the relationship of the initial emergency department systolic blood pressure (EDSBP) with outcome...
  38. doi request reprint Efficacy of a clinical decision-support system in an HIV practice: a randomized trial
    Gregory K Robbins
    Massachusetts General Hospital, Division of Infectious Diseases, 55 Fruit Street, Cox 5, Boston, MA 02114, USA
    Ann Intern Med 157:757-66. 2012
    ..Data to support improved patient outcomes from clinical decision-support systems (CDSSs) are lacking in HIV care...
  39. doi request reprint Missed opportunities for primary repair in complicated acute diverticulitis
    Malek Tabbara
    Harvard Medical School, Boston, MA, USA
    Surgery 148:919-24. 2010
    ..We aim to identify patient characteristics predicting successful PR and explore if patients are managed by FD despite the presence of such characteristics...
  40. doi request reprint Relationship between patient panel characteristics and primary care physician clinical performance rankings
    Clemens S Hong
    School of Medicine, Harvard University, and General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts 02115, USA
    JAMA 304:1107-13. 2010
    ..Physicians have increasingly become the focus of clinical performance measurement...
  41. doi request reprint Is concern about post-cessation weight gain a barrier to smoking cessation among pregnant women?
    Carla J Berg
    Massachusetts General Hospital Harvard Medical School, Boston, MA 02114, USA
    Nicotine Tob Res 10:1159-63. 2008
    ..63-2.68) or postpartum (OR = 2.18, 95% CI 0.93-5.10). In conclusion, women who are more concerned about post-cessation weight gain may be less likely to quit smoking during pregnancy or remain abstinent in the postpartum period...
  42. pmc Phosphorus binders and survival on hemodialysis
    Tamara Isakova
    Renal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Soc Nephrol 20:388-96. 2009
    ..Although confirmatory studies are needed in the dialysis setting, future placebo-controlled, randomized trials of phosphorus binders might focus on predialysis patients with chronic kidney disease and normal serum phosphate levels...
  43. pmc A cluster-randomized trial of a primary care informatics-based system for breast cancer screening
    Steven J Atlas
    General Medicine Division, Massachusetts General Hospital, Harvard Medical School, 50 Staniford Street, Boston, MA 02114, USA
    J Gen Intern Med 26:154-61. 2011
    ..Information technology offers the promise, as yet unfulfilled, of delivering efficient, evidence-based health care...
  44. doi request reprint Association of prehospital advanced airway management with neurologic outcome and survival in patients with out-of-hospital cardiac arrest
    Kohei Hasegawa
    Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, 326 Cambridge St, Ste 410, Boston, MA 02114, USA
    JAMA 309:257-66. 2013
    ....
  45. pmc A new risk scheme to predict ischemic stroke and other thromboembolism in atrial fibrillation: the ATRIA study stroke risk score
    Daniel E Singer
    Clinical Epidemiology Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    J Am Heart Assoc 2:e000250. 2013
    ....
  46. pmc Augmenting advance care planning in poor prognosis cancer with a video decision aid: a preintervention-postintervention study
    Angelo E Volandes
    General Medicine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Cancer 118:4331-8. 2012
    ..The authors tested whether an educational video on the goals of care in advanced cancer (life-prolonging care, basic care, or comfort care) helped patients understand these goals and had an impact on their preferences for resuscitation...
  47. doi request reprint Prediction of functional outcome in patients with primary intracerebral hemorrhage: the FUNC score
    Natalia S Rost
    Massachusetts General Hospital, Center for Human Genetic Research, Boston, MA 02114, USA
    Stroke 39:2304-9. 2008
    ..We developed an acute clinical score to predict likelihood of functional independence...
  48. pmc Perceived support to stay quit: what happens after delivery?
    Elyse R Park
    Massachusetts General Hospital, 9th Floor, Boston, MA 02114, USA
    Addict Behav 34:1000-4. 2009
    ..To assess whether perceived changes in postpartum support were associated with postpartum return to smoking...
  49. pmc Effectiveness of pediatric antiretroviral therapy in resource-limited settings: a systematic review and meta-analysis
    Andrea L Ciaranello
    The Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Infect Dis 49:1915-27. 2009
    ..We sought to derive pooled estimates of the 12-month rate of virologic suppression (HIV RNA, <400 copies/mL) and gain in CD4 cell percentage (DeltaCD4%) for children initiating ART in resource-limited settings...
  50. pmc Parent smoker role conflict and planning to quit smoking: a cross-sectional study
    Joan Friebely
    Center for Child and Adolescent Health Research and Policy, Massachusetts General Hospital, Boston, MA, USA
    BMC Public Health 13:164. 2013
    ..A similar strategy was used to determine whether role conflict was independently associated with intention to quit in the next 30 days...
  51. pmc Population-based breast cancer screening in a primary care network
    Steven J Atlas
    General Medicine Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Manag Care 18:821-9. 2012
    ..To assess the ability of a health information technology system to facilitate population- based breast cancer screening...
  52. doi request reprint Successful nonoperative management of the most severe blunt liver injuries: a multicenter study of the research consortium of new England centers for trauma
    Gwendolyn M van der Wilden
    Department of Surgery, Division of Trauma, Emergency Surgery, and Surgical Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Arch Surg 147:423-8. 2012
    ..Grade 4 and grade 5 blunt liver injuries can be safely treated by nonoperative management (NOM)...
  53. pmc Use of video to facilitate end-of-life discussions with patients with cancer: a randomized controlled trial
    Areej El-Jawahri
    Departments of Medicine, Neurology and Cancer Center, and Oncology, Massachusetts General Hospital, 50 Staniford St, 9th Floor, Boston, MA 02114, USA
    J Clin Oncol 28:305-10. 2010
    ..To determine whether the use of a goals-of-care video to supplement a verbal description can improve end-of-life decision making for patients with cancer...
  54. pmc Plasma gelsolin and circulating actin correlate with hemodialysis mortality
    Po Shun Lee
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Soc Nephrol 20:1140-8. 2009
    ..9 to 33.5). Worsening renal function correlated with pGSN decline in 53 subjects with CKD not on dialysis. In summary, low pGSN and detectable circulating actin identify chronic hemodialysis patients at highest risk for 1-yr mortality...
  55. ncbi request reprint The impact of disability compensation on long-term treatment outcomes of patients with sciatica due to a lumbar disc herniation
    Steven J Atlas
    General Medicine Division, Medical Services, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Spine (Phila Pa 1976) 31:3061-9. 2006
    ..Prospective, observational study...
  56. doi request reprint Assessing end-of-life preferences for advanced dementia in rural patients using an educational video: a randomized controlled trial
    Angelo E Volandes
    General Medicine Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
    J Palliat Med 14:169-77. 2011
    ..Few studies have evaluated the end-of-life preferences of elderly patients in rural communities and whether preferences are associated with level of health literacy...
  57. doi request reprint Management of the most severely injured spleen: a multicenter study of the Research Consortium of New England Centers for Trauma (ReCONECT)
    George C Velmahos
    Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02030, USA
    Arch Surg 145:456-60. 2010
    ..To determine the rate and predictors of failure of nonoperative management (NOM) in grade IV and V blunt splenic injuries (BSI)...
  58. doi request reprint The triple work-up for emergency department patients with acute chest pain: how often does it occur?
    Jonathan G Rogg
    Tufts University School of Medicine, Boston, Massachusetts, USA
    J Emerg Med 40:128-34. 2011
    ..To measure the degree of overlap and diagnostic yield for evaluations of acute coronary syndrome (ACS), pulmonary embolism (PE), and aortic dissection (AD) among Emergency Department (ED) patients...
  59. doi request reprint Patients with traumatic subarachnoid hemorrhage are at low risk for deterioration or neurosurgical intervention
    Pierre Borczuk
    Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Trauma Acute Care Surg 74:1504-9. 2013
    ..We hypothesize that a set of low-risk criteria can be applied to such patients to identify those who may not require neurosurgical evaluation...
  60. pmc Measuring decision quality: psychometric evaluation of a new instrument for breast cancer surgery
    Karen R Sepucha
    General Medicine Division, Massachusetts General Hospital, and Harvard Medical School, Boston, MA 02114, USA
    BMC Med Inform Decis Mak 12:51. 2012
    ..The purpose of this paper is to examine the acceptability, feasibility, reliability and validity of a new decision quality instrument that assesses the extent to which patients are informed and receive treatments that match their goals...
  61. doi request reprint A long-term analysis of physician triage screening in the emergency department
    Jonathan G Rogg
    Harvard Affiliated Emergency Medicine Residency, Boston, MA, USA
    Acad Emerg Med 20:374-80. 2013
    ..The authors hypothesized that a physician triage screening program (Supplemented Triage and Rapid Treatment [START]) sustainably improves standard ED performance metrics...
  62. doi request reprint Supplemented Triage and Rapid Treatment (START) improves performance measures in the emergency department
    Benjamin A White
    Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Emerg Med 42:322-8. 2012
    ..Emergency Department (ED) crowding is well recognized, and multiple studies have demonstrated its negative effect on patient care...
  63. doi request reprint Vitamin D receptor activation and left ventricular hypertrophy in advanced kidney disease
    Ravi Thadhani
    Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, USA
    Am J Nephrol 33:139-49. 2011
    ..In chronic kidney disease (CKD), left ventricular hypertrophy (LVH) is prevalent and is associated with increased cardiovascular morbidity and mortality. Vitamin D receptor (VDR) activation attenuates LVH progression in animal models...
  64. doi request reprint Candida infection and colonization among non-trauma emergency surgery patients
    Themistoklis Kourkoumpetis
    Division of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Virulence 1:359-66. 2010
    ..Herein we describe the incidence of both colonization and infection from Candida and risk factors for invasive disease in this population...
  65. pmc Predicting virologic failure in an HIV clinic
    Gregory K Robbins
    Harvard Medical School, Boston, Massachusetts, USA
    Clin Infect Dis 50:779-86. 2010
    ..We sought to use data captured in the electronic health record (EHR) to develop and validate a prediction rule for virologic failure among patients being treated for infection with human immunodeficiency virus (HIV)...
  66. doi request reprint Blunt pancreatoduodenal injury: a multicenter study of the Research Consortium of New England Centers for Trauma (ReCONECT)
    George C Velmahos
    Departments of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Arch Surg 144:413-9; discussion 419-20. 2009
    ..To evaluate the safety of nonoperative management (NOM), to examine the diagnostic sensitivity of computed tomography (CT), and to identify missed diagnoses and related outcomes in patients with blunt pancreatoduodenal injury (BPDI)...
  67. doi request reprint Determinants of white matter hyperintensity volume in patients with acute ischemic stroke
    Natalia S Rost
    Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    J Stroke Cerebrovasc Dis 19:230-5. 2010
    ..It is unclear whether WMH represents a single or multiple biological processes. We sought to investigate the extent and determinants of WMH in patients with acute ischemic stroke (AIS)...
  68. doi request reprint Extracorporeal membrane oxygenation for nonneonatal acute respiratory failure: the Massachusetts General Hospital experience from 1990 to 2008
    Deepika Nehra
    Division of Pediatric Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
    Arch Surg 144:427-32; discussion 432. 2009
    ..To determine the efficacy of extracorporeal membrane oxygenation (ECMO) for nonneonatal acute respiratory failure...
  69. ncbi request reprint The predictive value of sympathetic block for the success of spinal cord stimulation
    E Daniela Hord
    Interventional Pain Program, MGH Pain Center, Departments of Anesthesia and Critical Care and Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Neurosurgery 53:626-32; discussion 632-3. 2003
    ..The purpose of this study was to assess the predictive value of response to sympathetic blockade (SB) on the success rate of spinal cord stimulation (SCS) in patients with complex regional pain syndrome...
  70. ncbi request reprint Evidence of focal small-fiber axonal degeneration in complex regional pain syndrome-I (reflex sympathetic dystrophy)
    Anne Louise Oaklander
    Nerve Injury Unit, Departments of Anesthesiology, Neurology, and Neuropathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Pain 120:235-43. 2006
    ..These results support the hypothesis that CRPS-I is specifically associated with post-traumatic focal MDNI affecting nociceptive small-fibers. This type of nerve injury will remain undetected in most clinical settings...
  71. ncbi request reprint Dynamic single-section CT demonstrates reduced cerebral blood flow in acute intracerebral hemorrhage
    Jonathan Rosand
    Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Cerebrovasc Dis 14:214-20. 2002
    ..A gradient of hypoperfusion appears to extend at least 4 mm beyond the hematoma edge and may be time dependent. Whether reduced CBF is associated with perihematoma ischemia requires additional study...
  72. ncbi request reprint A utilization management intervention to reduce unnecessary testing in the coronary care unit
    Thomas J Wang
    Massachusetts General Hospital, Wang Ambulatory Care Center 478, 15 Parkman St, Boston, MA 02114, USA
    Arch Intern Med 162:1885-90. 2002
    ..There have been no studies of interventions to reduce test utilization in the coronary care unit...
  73. doi request reprint Effect of effort pain after upper abdominal surgery on two independent measures of respiratory function
    William R Kimball
    Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, MA 02114, USA
    J Clin Anesth 20:200-5. 2008
    ..To determine how effort pain interacts with changing pulmonary function after upper abdominal incisions...
  74. pmc Regional pulmonary perfusion, inflation, and ventilation defects in bronchoconstricted patients with asthma
    R Scott Harris
    Department of Medicine Pulmonary and Critical Care Unit and General Medicine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Am J Respir Crit Care Med 174:245-53. 2006
    ..However, the regional adaptations of pulmonary perfusion (Q) to such ventilation defects have not been well studied...
  75. ncbi request reprint Prognostic histologic indicators of curatively resected hepatocellular carcinomas: a multi-institutional analysis of 425 patients with definition of a histologic prognostic index
    Gregory Y Lauwers
    Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Surg Pathol 26:25-34. 2002
    ..The combination of these histologic parameters provides adequate prognostic stratification...
  76. ncbi request reprint INCOMING!--A web tracking application for PACU and post-surgical patients
    Mark A Meyer
    Laboratory of Computer Science, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Surg Res 132:153-8. 2006
    ..An integrated real time system facilitating patient flow between the post-anesthesia care unit (PACU) and surgical ward would ease PACU workload by reducing the effort of discharging patients...
  77. ncbi request reprint Disparity in use of orthotopic liver transplantation among blacks and whites
    Andrea E Reid
    Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    Liver Transpl 10:834-41. 2004
    ..Although waiting times were similar once listed, black race affected outcomes while awaiting OLT. The process of referral and evaluation for OLT should be investigated further...
  78. ncbi request reprint Effects of removing gatekeeping on specialist utilization by children in a health maintenance organization
    Timothy G Ferris
    Insititute for Health Policy, Division of General Internal Medicine, Massachusetts General Hospital Partners Healthcare System and Harvard Medical School, Boston, MA 02114, USA
    Arch Pediatr Adolesc Med 156:574-9. 2002
    ..The "gatekeeping" model of access to specialty care has been an essential managed care tool, intended to control costs of care and promote coordination between generalists and specialists...
  79. ncbi request reprint Pulmonary artery occlusion increases the ratio of diffusing capacity for nitric oxide to carbon monoxide in prone sheep
    R Scott Harris
    Pulmonary and Critical Care Unit, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USAL
    Chest 126:559-65. 2004
    ..To test the hypothesis that the ratio of diffusing capacity of the lung for nitric oxide (DLno) to diffusing capacity of the lung for carbon monoxide (DLco) would be affected by occlusion of a fraction of the pulmonary vascular bed...
  80. ncbi request reprint Soluble guanylate cyclase activator reverses acute pulmonary hypertension and augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs
    Oleg V Evgenov
    Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, CLN 309, Boston, Mass 02114, USA
    Circulation 110:2253-9. 2004
    ..We examined whether direct stimulation of sGC by BAY 41-2272 would produce pulmonary vasodilation and augment the pulmonary responses to inhaled NO or CO...
  81. ncbi request reprint A review of police pursuit fatalities in the United States from 1982-2004
    H Range Hutson
    Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    Prehosp Emerg Care 11:278-83. 2007
    ..High-speed police pursuits are common in the United States (US). Most states do not gather statistics on police pursuits, pursuit crashes, injuries or fatalities for annual review...
  82. doi request reprint A mixed-methods study of the quality of care provided to patients boarding in the emergency department: comparing emergency department and inpatient responsibility models
    Shan W Liu
    1Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Med Care Res Rev 69:679-98. 2012
    ..A theoretically better responsibility model may not deliver better care to boarded patients because of cultural, resource prioritization, and systems issues...
  83. doi request reprint Effect of acute posttrauma propranolol on PTSD outcome and physiological responses during script-driven imagery
    Elizabeth A Hoge
    Department of Psychiatry, Massachusetts General Hospital, Boston, USA
    CNS Neurosci Ther 18:21-7. 2012
    ..Previous studies have attempted to use pharmaceutical agents, especially the β-adrenergic blocker propranolol, to reduce this overconsolidation...
  84. pmc Diabetes differentially affects depression and self-rated health by age in the U.S
    Deborah J Wexler
    Massachusetts General Hospital Diabetes Center and Harvard Medical School, Boston, MA, USA
    Diabetes Care 35:1575-7. 2012
    ..To determine whether the relationship between age and physical and mental health varies by diabetes status in older U.S. adults...
  85. doi request reprint Accuracy of microscopic urine analysis and chest radiography in patients with severe sepsis and septic shock
    Roberta Capp
    Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts 02115, USA
    J Emerg Med 42:52-7. 2012
    ..Diagnosis of source of infection in patients with septic shock and severe sepsis needs to be done rapidly and accurately to guide appropriate antibiotic therapy...
  86. doi request reprint Clinical predictors of significant findings on head computed tomographic angiography
    Soheil Jamshidi
    Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
    J Emerg Med 40:469-75. 2011
    ..Although head computed tomographic angiography (CTA) is a sensitive tool for the evaluation of neurological symptoms in the emergency department (ED), little is known about which clinical signs predict significant CTA findings...
  87. pmc Access to medications and medical care after participation in HIV clinical trials: a systematic review of trial protocols and informed consent documents
    Andrea L Ciaranello
    Division of Infectious Disease, Massachusetts General Hospital, Boston, MA 02114, USA
    HIV Clin Trials 10:13-24. 2009
    ..We describe the frequency with which these posttrial services are described in the protocols and informed consent forms (ICFs) of antiretroviral drug (ARV) trials...
  88. doi request reprint Surgical outcomes of open cholecystectomy in the laparoscopic era
    Andrea S Wolf
    Department of Surgery, Massachusetts General Hospital, Boston, MA, USA
    Am J Surg 197:781-4. 2009
    ..Because the total number of cholecystectomies is increasing with time, the average patient undergoing open cholecystectomy in the laparoscopic era is older and has more comorbidities...
  89. doi request reprint The effect of neoadjuvant chemoradiation therapy on the prognostic value of lymph nodes after rectal cancer surgery
    Coen L Klos
    Division of General and Gastrointestinal Surgery, Massachusetts General Hospital, 15 Parkman St, WAC 460, Boston, MA 02114, USA
    Am J Surg 200:440-5. 2010
    ..Neoadjuvant therapy may affect the prognostic impact of total lymph node harvests and lymph node positivity after surgery for rectal cancer...
  90. ncbi request reprint Bupropion for smokers hospitalized with acute cardiovascular disease
    Nancy A Rigotti
    Tobacco Research and Treatment Center, General Medicine Division, and Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    Am J Med 119:1080-7. 2006
    ..Bupropion is effective for smoking cessation, but its safety and efficacy in hospitalized smokers with acute cardiovascular disease is unknown...
  91. ncbi request reprint The sensitivity of cardiac markers stratified by symptom duration
    John T Nagurney
    Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Emerg Med 29:409-15. 2005
    ..For troponin I, the increase in sensitivity approaches threefold...
  92. pmc Video decision support tool for advance care planning in dementia: randomised controlled trial
    Angelo E Volandes
    General Medicine Unit, Department of Medicine, Massachusetts General Hospital, 50 Staniford Street, Boston, MA 02114, USA
    BMJ 338:b2159. 2009
    ..To evaluate the effect of a video decision support tool on the preferences for future medical care in older people if they develop advanced dementia, and the stability of those preferences after six weeks...
  93. doi request reprint Heart rate variability as a triage tool in patients with trauma during prehospital helicopter transport
    David R King
    Division of Trauma, Emergency Surgery, and Surgical Critical Care, Massachusetts General Hospital andHarvard Medical School, 165 Cambridge Street, Suite 810, Boston, MA 02141, USA
    J Trauma 67:436-40. 2009
    ..The purpose of this study was to prospectively test whether heart rate variability (HRV) could be used as a triage tool during helicopter transport of civilian patients with trauma...
  94. pmc Is this "my" patient? Development and validation of a predictive model to link patients to primary care providers
    Steven J Atlas
    General Medicine Division, Medical Services, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Gen Intern Med 21:973-8. 2006
    ..Evaluating the quality of care provided by individual primary care physicians (PCPs) may be limited by failing to know which patients the PCP feels personally responsible for...
  95. doi request reprint N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations in hemodialysis patients: prognostic value of baseline and follow-up measurements
    ORLANDO M GUTIERREZ
    Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Clin Chem 54:1339-48. 2008
    ..Previous studies focused on prevalent dialysis patients and examined single measurements of NT-proBNP in time...
  96. ncbi request reprint The "gender gap" in authorship of academic medical literature--a 35-year perspective
    Reshma Jagsi
    Department of Radiation Oncology, Office for Women s Careers, Massachusetts General Hospital, Boston, MA 02114, USA
    N Engl J Med 355:281-7. 2006
    ..Advancement is largely driven by peer-reviewed original research, so we sought to determine the representation of female physician-investigators among the authors of selected publications during the past 35 years...
  97. ncbi request reprint Efficacy of telephone counseling for pregnant smokers: a randomized controlled trial
    Nancy A Rigotti
    Tobacco Research and Treatment Center, Institute for Health Policy, General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Obstet Gynecol 108:83-92. 2006
    ..Telephone counseling is an effective smoking cessation method that could offer pregnant women convenient access to more intensive smoking cessation counseling...
  98. ncbi request reprint Isolated prehospital hypotension after traumatic injuries: a predictor of mortality?
    Nathan I Shapiro
    Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Emerg Med 25:175-9. 2003
    ..9 (1.1-7.6, p < 0.03). In this study of normotensive trauma center patients, prehospital hypotension was associated with increased risk of mortality and significant chest or abdominal injury...
  99. ncbi request reprint Predictors of delay in presentation to the ED in patients with suspected acute coronary syndromes
    Shamai A Grossman
    Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston 02215, USA
    Am J Emerg Med 21:425-8. 2003
    ..Contrary to previously published data, patients with symptoms suspicious for ACS can delay an average of 9 hours, which might alter current thinking in the prevention and care of these patients...
  100. ncbi request reprint Pancreatic tissue sampling guided by EUS, CT/US, and surgery: a comparison of sensitivity and specificity
    J Shawn Mallery
    Department of Medicine, Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Gastrointest Endosc 56:218-24. 2002
    ..Biopsies may be directed by using EUS, CT, US, or surgery. This study retrospectively compared the accuracy of EUS-guided, CT/US-guided, and surgical tissue sampling of the pancreas over a 5-year period...
  101. ncbi request reprint Disagreement between formal and medical record criteria for the diagnosis of acute coronary syndrome
    John T Nagurney
    Department of Emergency Medicine, Clinics 115, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02115, USA
    Acad Emerg Med 12:446-52. 2005
    ..To measure agreement between formal and medical record criteria for the diagnosis of acute coronary syndrome (ACS) among patients undergoing an emergency department evaluation for potential acute coronary symptoms...