Claudia Chae

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Vitamin E supplementation and the risk of heart failure in women
    Claudia U Chae
    Cardiology Division, Massachusetts General Hospital, Boston, MA 02114, USA
    Circ Heart Fail 5:176-82. 2012
  2. pmc Aging syndrome genes and premature coronary artery disease
    Adrian F Low
    Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA
    BMC Med Genet 6:38. 2005
  3. doi The menopausal transition and cardiovascular risk
    Claudia U Chae
    Department of Medicine, Harvard Medical School, Cardiology Division, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Obstet Gynecol Clin North Am 38:477-88. 2011
  4. ncbi Blood pressure and inflammation in apparently healthy men
    C U Chae
    Center for Cardiovascular Disease Prevention, Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Hypertension 38:399-403. 2001
  5. ncbi Mild renal insufficiency and risk of congestive heart failure in men and women > or =70 years of age
    Claudia U Chae
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215 1204, USA
    Am J Cardiol 92:682-6. 2003
  6. ncbi Renal function, congestive heart failure, and amino-terminal pro-brain natriuretic peptide measurement: results from the ProBNP Investigation of Dyspnea in the Emergency Department (PRIDE) Study
    Saif Anwaruddin
    Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Am Coll Cardiol 47:91-7. 2006
  7. ncbi Prospective study of sudden cardiac death among women in the United States
    Christine M Albert
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave East, Boston, Mass 02215 1204, USA
    Circulation 107:2096-101. 2003
  8. doi Ethnic differences in C-reactive protein concentrations
    Alyson Kelley-Hedgepeth
    Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA, USA
    Clin Chem 54:1027-37. 2008
  9. ncbi Measurement of the interleukin family member ST2 in patients with acute dyspnea: results from the PRIDE (Pro-Brain Natriuretic Peptide Investigation of Dyspnea in the Emergency Department) study
    James L Januzzi
    Department of Medicine and Laboratory Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Am Coll Cardiol 50:607-13. 2007
  10. ncbi Dietary intakes of flavonols and flavones and coronary heart disease in US women
    Jennifer Lin
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Am J Epidemiol 165:1305-13. 2007

Research Grants

Collaborators

Detail Information

Publications23

  1. pmc Vitamin E supplementation and the risk of heart failure in women
    Claudia U Chae
    Cardiology Division, Massachusetts General Hospital, Boston, MA 02114, USA
    Circ Heart Fail 5:176-82. 2012
    ..No large clinical trials have addressed the role of antioxidant therapy in the primary prevention of HF...
  2. pmc Aging syndrome genes and premature coronary artery disease
    Adrian F Low
    Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA
    BMC Med Genet 6:38. 2005
    ..We evaluated whether common variants at the LMNA or KLOTHO genes are associated with rigorously defined premature CAD...
  3. doi The menopausal transition and cardiovascular risk
    Claudia U Chae
    Department of Medicine, Harvard Medical School, Cardiology Division, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Obstet Gynecol Clin North Am 38:477-88. 2011
    ..Whether these changes are due to aging or to menopause itself, increased attention to risk factor modification in the pre- and perimenopausal years will help reduce future cardiovascular disease risk among women...
  4. ncbi Blood pressure and inflammation in apparently healthy men
    C U Chae
    Center for Cardiovascular Disease Prevention, Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Hypertension 38:399-403. 2001
    ..These data suggest that increased blood pressure may be a stimulus for inflammation and that this is a possible mechanism underlying the well-established role of hypertension as a risk factor for atherosclerotic disease...
  5. ncbi Mild renal insufficiency and risk of congestive heart failure in men and women > or =70 years of age
    Claudia U Chae
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215 1204, USA
    Am J Cardiol 92:682-6. 2003
    ..43, 95% CI 1.17 to 1.74). Thus, mild renal insufficiency was a strong independent predictor of CHF in this cohort, suggesting that serum creatinine may offer a readily accessible tool to identify elderly patients at risk for CHF...
  6. ncbi Renal function, congestive heart failure, and amino-terminal pro-brain natriuretic peptide measurement: results from the ProBNP Investigation of Dyspnea in the Emergency Department (PRIDE) Study
    Saif Anwaruddin
    Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Am Coll Cardiol 47:91-7. 2006
    ..Even in the presence of renal insufficiency, NT-proBNP remained a valuable tool for the diagnosis of acute congestive heart failure and it provides important prognostic information...
  7. ncbi Prospective study of sudden cardiac death among women in the United States
    Christine M Albert
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave East, Boston, Mass 02215 1204, USA
    Circulation 107:2096-101. 2003
    ..Nonetheless, existing data, although sparse, suggest possible gender differences in risk factors for SCD...
  8. doi Ethnic differences in C-reactive protein concentrations
    Alyson Kelley-Hedgepeth
    Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA, USA
    Clin Chem 54:1027-37. 2008
    ..We hypothesized that known CVD risk factors, including anthropometric characteristics, would explain much of the observed ethnic variation in CRP...
  9. ncbi Measurement of the interleukin family member ST2 in patients with acute dyspnea: results from the PRIDE (Pro-Brain Natriuretic Peptide Investigation of Dyspnea in the Emergency Department) study
    James L Januzzi
    Department of Medicine and Laboratory Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Am Coll Cardiol 50:607-13. 2007
    ..The aim of this study was to examine the value of measurement of the interleukin-1 receptor family member ST2 in patients with dyspnea...
  10. ncbi Dietary intakes of flavonols and flavones and coronary heart disease in US women
    Jennifer Lin
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Am J Epidemiol 165:1305-13. 2007
    ..93; p for trend = 0.04). The lower risk associated with kaempferol intake was probably attributable to broccoli consumption. These prospective data do not support an inverse association between flavonol or flavone intake and CHD risk...
  11. ncbi Association of atrial fibrillation and amino-terminal pro-brain natriuretic peptide concentrations in dyspneic subjects with and without acute heart failure: results from the ProBNP Investigation of Dyspnea in the Emergency Department (PRIDE) study
    Angela Morello
    Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Am Heart J 153:90-7. 2007
    ..Atrial fibrillation (AF) may cause dyspnea in the absence of acute HF and may also affect plasma levels of NT-proBNP...
  12. ncbi Coronary multidetector computed tomography in the assessment of patients with acute chest pain
    Udo Hoffmann
    Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 165 Charles River Plaza, Ste 400, Boston, MA 02114, USA
    Circulation 114:2251-60. 2006
    ....
  13. ncbi MDCT in early triage of patients with acute chest pain
    Udo Hoffmann
    Department of Radiology, Massachusetts General Hospital Cardiac MR CT PET Program and Harvard Medical School, 100 CPZ 400, Boston, MA 02114, USA
    AJR Am J Roentgenol 187:1240-7. 2006
    ..We sought to determine whether contrast-enhanced MDCT-based detection of stenosis is feasible and improves early and accurate triage of patients with acute chest pain...
  14. ncbi Nonsteroidal antiinflammatory drugs, acetaminophen, and the risk of cardiovascular events
    Andrew T Chan
    Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Circulation 113:1578-87. 2006
    ..Although randomized trials of cyclooxygenase-2 (COX-2) inhibitors have shown increased cardiovascular risk, studies of nonselective, nonsteroidal antiinflammatory drugs (NSAIDs) and acetaminophen have been inconsistent...
  15. ncbi Utility of amino-terminal pro-brain natriuretic peptide testing for prediction of 1-year mortality in patients with dyspnea treated in the emergency department
    James L Januzzi
    Department of Internal Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    Arch Intern Med 166:315-20. 2006
    ..Amino-terminal pro-brain natriuretic peptide (NT-proBNP) is useful for diagnosis and triage of patients with dyspnea, but its role for predicting outcomes in such patients remains undefined...
  16. ncbi Dietary alpha-linolenic acid intake and risk of sudden cardiac death and coronary heart disease
    Christine M Albert
    Center for Arrhythmia Prevention, Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215 1204, USA
    Circulation 112:3232-8. 2005
    ..Alpha-linolenic acid, an intermediate-chain n-3 fatty acid found primarily in plants, may decrease the risk of fatal coronary heart disease (CHD) through a reduction in fatal ventricular arrhythmias and sudden cardiac death (SCD)...
  17. ncbi Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 29-2004. A 75-year-old woman with acute onset of chest pain followed by fever
    Adolf W Karchmer
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center Boston, USA
    N Engl J Med 351:1240-8. 2004
  18. ncbi Ethnic variation in hypertension among premenopausal and perimenopausal women: Study of Women's Health Across the Nation
    Donald M Lloyd-Jones
    Division of Cardiology, Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Hypertension 46:689-95. 2005
    ..Treatment and control rates vary considerably across ethnicities. Greater efforts must be made to improve hypertension awareness, treatment, and control in all middle-aged women, particularly those in ethnic minority groups...
  19. ncbi Effect of body mass index on natriuretic peptide levels in patients with acute congestive heart failure: a ProBNP Investigation of Dyspnea in the Emergency Department (PRIDE) substudy
    Daniel G Krauser
    Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    Am Heart J 149:744-50. 2005
    ..Neither the mechanism of natriuretic peptide suppression in the obese patient nor whether obesity affects natriuretic peptide levels among patients with acute CHF is known...
  20. ncbi The N-terminal Pro-BNP investigation of dyspnea in the emergency department (PRIDE) study
    James L Januzzi
    Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Cardiol 95:948-54. 2005
    ..NT-proBNP measurement is a valuable addition to standard clinical assessment for the identification and exclusion of acute CHF in the emergency department setting...
  21. ncbi Phobic anxiety and risk of coronary heart disease and sudden cardiac death among women
    Christine M Albert
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215 1204, USA
    Circulation 111:480-7. 2005
    ..To the best of our knowledge, no studies have looked at this association among women. Anxiety may influence CHD mortality by increasing the risk of ventricular arrhythmia and SCD...
  22. ncbi Physical exertion, exercise, and sudden cardiac death in women
    William Whang
    Cardiovascular Division, Massachusetts General Hospital, Boston, USA
    JAMA 295:1399-403. 2006
    ..Exercise is associated with a lower risk of cardiovascular events but may transiently increase the risk of ventricular arrhythmias. Its short-term and long-term associations with risk of sudden cardiac death among women are unclear...
  23. ncbi Relation of lower hematocrit to progression from asymptomatic left ventricular dysfunction to symptomatic heart failure (from the Studies of Left Ventricular Dysfunction Prevention trial)
    Sandeep R Das
    Donald W Reynolds Cardiovascular Clinical Research Center, Dallas, Texas, USA
    Am J Cardiol 96:827-31. 2005
    ..37 to 2.34), first HF hospitalization (HR 2.35, 95% CI 1.52 to 3.62), and death or the development of HF symptoms (HR 1.60, 95% CI 1.28 to 1.99) compared with patients in the highest hematocrit quartile (hematocrit > 46%)...

Research Grants1

  1. RISK FACTORS FOR CONGESTIVE HEART FAILURE IN WOMEN
    Claudia Chae; Fiscal Year: 2003
    The purpose of this award is to prepare the candidate, Dr. Claudia Chae, for a career as an independent clinical scientist in cardiovascular epidemiology, with particular expertise in the prevention and treatment of congestive heart ..