Research Topics
| J H CateSummaryAffiliation: Massachusetts Institute of Technology Country: USA Publications
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Detail Information
Publications
X-ray crystal structures of 70S ribosome functional complexesJ H Cate
Center for Molecular Biology of RNA, Sinsheimer Laboratories, University of California, Santa Cruz, CA 95064, USA
Science 285:2095-104. 1999....
Crystal structure of the ribosome at 5.5 A resolutionM M Yusupov
Center for Molecular Biology of RNA, Sinsheimer Laboratories, University of California at Santa Cruz, Santa Cruz, CA 95064, USA
Science 292:883-96. 2001..The tRNAs are closely juxtaposed with the intersubunit bridges, in a way that suggests coupling of the 20 to 50 angstrom movements associated with tRNA translocation with intersubunit movement...
The location of protein S8 and surrounding elements of 16S rRNA in the 70S ribosome from combined use of directed hydroxyl radical probing and X-ray crystallographyL Lancaster
Center for Molecular Biology of RNA, Sinsheimer Laboratories, University of California, Santa Cruz 95064, USA
RNA 6:717-29. 2000..The resulting model is in close agreement with the extensive body of data from previous studies using protein-protein and protein-RNA crosslinking, chemical and enzymatic footprinting, and genetics...
The path of messenger RNA through the ribosomeG Z Yusupova
Center for Molecular Biology of RNA, Sinsheimer Laboratories, University of California Santa Cruz, Santa Cruz, CA 95064, USA
Cell 106:233-41. 2001..The mRNA enters the ribosome around position +13 to +15, the location of downstream pseudoknots that stimulate -1 translational frame shifting...
Identification of an RNA-protein bridge spanning the ribosomal subunit interfaceG M Culver
Center for Molecular Biology of RNA, Sinsheimer Laboratories, University of California, Santa Cruz, CA 95064, USA
Science 285:2133-6. 1999..The 715 loop is specifically protected by binding free S15 to 50S subunits. Moreover, the previously determined structure of a homologous stem-loop from U2 small nuclear RNA fits closely to the electron density of the bridge...
