DAVID NORMAN CAPLAN

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint A study of syntactic processing in aphasia I: behavioral (psycholinguistic) aspects
    David Caplan
    Neuropsychology Laboratory, Massachusetts General Hospital, Boston, MA, USA
    Brain Lang 101:103-50. 2007
  2. pmc Dissociations and associations of performance in syntactic comprehension in aphasia and their implications for the nature of aphasic deficits
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, United States Electronic address
    Brain Lang 127:21-33. 2013
  3. pmc Short-term memory, working memory, and syntactic comprehension in aphasia
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
    Cogn Neuropsychol 30:77-109. 2013
  4. pmc Memory mechanisms supporting syntactic comprehension
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, 175 Cambridge Street, Suite 340, Boston, MA 02114, USA
    Psychon Bull Rev 20:243-68. 2013
  5. pmc Effects of syntactic complexity, semantic reversibility, and explicitness on discourse comprehension in persons with aphasia and in healthy controls
    Joshua Levy
    University of Massachusetts Amherst, USA
    Am J Speech Lang Pathol 21:S154-65. 2012
  6. pmc Effects of tasks on BOLD signal responses to sentence contrasts: Review and commentary
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Brain Lang 120:174-86. 2012
  7. ncbi request reprint A study of syntactic processing in aphasia II: neurological aspects
    David Caplan
    Neuropsychology Laboratory, Massachusetts General Hospital, Boston, MA 02114, USA
    Brain Lang 101:151-77. 2007
  8. ncbi request reprint Aphasic deficits in syntactic processing
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Cortex 42:797-804. 2006
  9. pmc Experimental design and interpretation of functional neuroimaging studies of cognitive processes
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Hum Brain Mapp 30:59-77. 2009
  10. pmc Syntactic and thematic constraint effects on blood oxygenation level dependent signal correlates of comprehension of relative clauses
    David Caplan
    Massachusetts General Hospital, Boston, MA, USA
    J Cogn Neurosci 20:643-56. 2008

Research Grants

  1. Functional Neuroimaging Studies of Syntactic Comprehension
    David Caplan; Fiscal Year: 2007
  2. PET STUDIES OF SENTENCE COMPREHENSION
    David Caplan; Fiscal Year: 1999
  3. AN INVESTIGATION OF THE TRACE DELETION HYPOTHESIS
    David Caplan; Fiscal Year: 2003
  4. FUNCTIONAL NEUROIMAGING STUDIES OF SYNTACTIC PROCESSING
    David Caplan; Fiscal Year: 2005
  5. Disorders of Syntactic Comprehension
    David Caplan; Fiscal Year: 2007
  6. FUNCTIONAL NEUROIMAGING STUDIES OF SYNTACTIC PROCESSING
    David Caplan; Fiscal Year: 2003
  7. FUNCTIONAL NEUROIMAGING STUDIES OF SYNTACTIC PROCESSING
    David Caplan; Fiscal Year: 2004
  8. Disorders of Syntactic Comprehension
    David Caplan; Fiscal Year: 2009
  9. Functional Neuroimaging Studies of Syntactic Comprehension
    David Caplan; Fiscal Year: 2009
  10. Disorders of Syntactic Comprehension
    DAVID NORMAN CAPLAN; Fiscal Year: 2010

Detail Information

Publications28

  1. ncbi request reprint A study of syntactic processing in aphasia I: behavioral (psycholinguistic) aspects
    David Caplan
    Neuropsychology Laboratory, Massachusetts General Hospital, Boston, MA, USA
    Brain Lang 101:103-50. 2007
    ..The results indicate that the major cause of aphasic impairments of syntactically based comprehension are intermittent reductions in the processing capacity available for syntactic, interpretive, and task-related operations...
  2. pmc Dissociations and associations of performance in syntactic comprehension in aphasia and their implications for the nature of aphasic deficits
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, United States Electronic address
    Brain Lang 127:21-33. 2013
    ..They point to the role of a reduction in processing resources and of the interaction of task demands and parsing and interpretive abilities in the genesis of patient performance...
  3. pmc Short-term memory, working memory, and syntactic comprehension in aphasia
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
    Cogn Neuropsychol 30:77-109. 2013
    ..The results are most easily related to the view that STM plays a facilitatory role in supporting the use of the products of the comprehension process to accomplish operations related to tasks. ..
  4. pmc Memory mechanisms supporting syntactic comprehension
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, 175 Cambridge Street, Suite 340, Boston, MA 02114, USA
    Psychon Bull Rev 20:243-68. 2013
    ..We propose a model of the relation of different aspects of parsing and interpretation to ST-WM and long-term working memory...
  5. pmc Effects of syntactic complexity, semantic reversibility, and explicitness on discourse comprehension in persons with aphasia and in healthy controls
    Joshua Levy
    University of Massachusetts Amherst, USA
    Am J Speech Lang Pathol 21:S154-65. 2012
    ..A discourse task was developed to assess the effect of syntactic complexity, among other factors, on discourse comprehension in PWA...
  6. pmc Effects of tasks on BOLD signal responses to sentence contrasts: Review and commentary
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Brain Lang 120:174-86. 2012
    ..In this review, we point to issues that arise in discriminating the effects of these concurrent processes from those of the parser/interpreter in neural measures and to approaches that may help resolve them...
  7. ncbi request reprint A study of syntactic processing in aphasia II: neurological aspects
    David Caplan
    Neuropsychology Laboratory, Massachusetts General Hospital, Boston, MA 02114, USA
    Brain Lang 101:151-77. 2007
    ..The data are consistent with a model in which the neural tissue that is responsible for the operations underlying sentence comprehension and syntactic processing is localized in different neural regions in different individuals...
  8. ncbi request reprint Aphasic deficits in syntactic processing
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Cortex 42:797-804. 2006
    ..This paper reviews the data upon which such theories are based and argues that they may support only the latter type of model...
  9. pmc Experimental design and interpretation of functional neuroimaging studies of cognitive processes
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Hum Brain Mapp 30:59-77. 2009
    ....
  10. pmc Syntactic and thematic constraint effects on blood oxygenation level dependent signal correlates of comprehension of relative clauses
    David Caplan
    Massachusetts General Hospital, Boston, MA, USA
    J Cogn Neurosci 20:643-56. 2008
    ....
  11. pmc Task-dependent and task-independent neurovascular responses to syntactic processing
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Cortex 44:257-75. 2008
    ....
  12. doi request reprint Effects of age, speed of processing, and working memory on comprehension of sentences with relative clauses
    David Caplan
    Laboratory, Department of Neurology, Caplan, Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychol Aging 26:439-50. 2011
    ..However, the poorer comprehension performance of older individuals indicates that their slower online processing reflects inefficient processing even at these points...
  13. ncbi request reprint Why is Broca's area involved in syntax?
    David Caplan
    Neuropsychology Laboratory, Massachusetts General Hospital, Boston, MA 02114, USA
    Cortex 42:469-71. 2006
    ....
  14. ncbi request reprint Using fMRI to discover cognitive operations
    David Caplan
    Neuropsychology Laboratory, Massachusetts General Hospital, Boston, MA 02114, USA
    Cortex 42:393-5; discussion 422-7. 2006
  15. ncbi request reprint Cognitive conjunction and cognitive functions
    David Caplan
    Neuropsychology Laboratory, Massachusetts General Hospital, Boston, MA, 02114, USA
    Neuroimage 21:751-6. 2004
    ....
  16. ncbi request reprint On-line syntactic processing in aphasia: studies with auditory moving window presentation
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Vincent Burnham 827, Massachusetts General Hospital, Fruit Street, Boston, MA 02114, USA
    Brain Lang 84:222-49. 2003
    ....
  17. ncbi request reprint Effects of syntactic features on sentence-picture matching in Broca's aphasics: a reply to Drai and Grodzinksy (2005)
    David Caplan
    Neuropsychology Laboratory, Massachusetts General Hospital, USA
    Brain Lang 96:129-34; discussion 157-70. 2006
    ..The result is inconsistent with the trace deletion hypothesis; we conclude that features of syntactic structure other than constituent movement are relevant to understanding performance variation in patients with Broca's aphasia...
  18. ncbi request reprint Distinct patterns of neural modulation during the processing of conceptual and syntactic anomalies
    Gina R Kuperberg
    Massachusetts General Hospital, Charlestown, MA 02129, USA
    J Cogn Neurosci 15:272-93. 2003
    ..This suggests that morphosyntactic and pragmatic information can be processed in different ways but by the same neural systems...
  19. ncbi request reprint Determinants of bold signal correlates of processing object-extracted relative clauses
    Evan Chen
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, Boston 02114, USA
    Cortex 42:591-604. 2006
    ..These results require a re-interpretation of previous results with the same materials using positron emission tomography...
  20. ncbi request reprint The relationship between age, verbal working memory, and language comprehension
    Gayle DeDe
    Communication Disorders Program, Department of Health Sciences, Boston University, Boston, MA 02215, USA
    Psychol Aging 19:601-16. 2004
    ....
  21. ncbi request reprint Vascular responses to syntactic processing: event-related fMRI study of relative clauses
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Vincent Burnham 827, Massachusetts General Hospital, Fruit Street, Boston, MA 02114, USA
    Hum Brain Mapp 15:26-38. 2002
    ..This study shows that a hemodynamic response associated with processing the syntactically complex portions of a sentence can be localized to one part of the dominant perisylvian association cortex...
  22. ncbi request reprint The relationship between age, processing speed, working memory capacity, and language comprehension
    Gloria Waters
    Boston University, Dept of Communication Disorders, 635 Commonwealth Ave, Boston, MA 02215, USA
    Memory 13:403-13. 2005
    ..The data are argued to provide evidence that the WM system used to structure sentences syntactically is separate from that used in other aspects of language comprehension...
  23. ncbi request reprint On-line syntactic processing under concurrent memory load
    Gloria Waters
    Department of Health Sciences, Boston University, Boston, Massachusetts 02215, USA
    Psychon Bull Rev 10:88-95. 2003
    ....
  24. ncbi request reprint Question/statement judgments: an fMRI study of intonation processing
    Colin P Doherty
    Neuropsychology Laboratory and MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, Massachusetts, USA
    Hum Brain Mapp 23:85-98. 2004
    ..The study provides data relevant to the location of regions responsive to intonationally marked illocutionary differences between questions and statements...
  25. ncbi request reprint Effects of age and speed of processing on rCBF correlates of syntactic processing in sentence comprehension
    David Caplan
    Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Hum Brain Mapp 19:112-31. 2003
    ..The results suggest that the speed of syntactic processing, but not age per se is related to the neural location where one aspect of syntactic processing is carried out...
  26. ncbi request reprint Electrophysiological distinctions in processing conceptual relationships within simple sentences
    Gina R Kuperberg
    Department of Psychiatry, Massachusetts General Hospital, Bldg 149, 13th Street, Charlestown, MA 02129, USA
    Brain Res Cogn Brain Res 17:117-29. 2003
    ..Our findings suggest a qualitative neural distinction in processing these two types of conceptual anomalies within simple, unambiguous sentences...
  27. ncbi request reprint The reliability and stability of verbal working memory measures
    Gloria S Waters
    Department of Health Sciences, Boston University, Boston, Massachusetts 02116, USA
    Behav Res Methods Instrum Comput 35:550-64. 2003
    ..Both test-retest reliability and stability of classification improved when a composite measure reflecting performance on several tasks was used...
  28. ncbi request reprint Cognition, emotion and the cerebellum
    Jeremy D Schmahmann
    Ataxia Unit, Massachusetts General Hospital Boston, MA, USA
    Brain 129:290-2. 2006

Research Grants33

  1. Functional Neuroimaging Studies of Syntactic Comprehension
    David Caplan; Fiscal Year: 2007
    ....
  2. PET STUDIES OF SENTENCE COMPREHENSION
    David Caplan; Fiscal Year: 1999
    ..The studies make use of several experimental paradigms in order to provide converging evidence regarding the localization of syntactic processing. ..
  3. AN INVESTIGATION OF THE TRACE DELETION HYPOTHESIS
    David Caplan; Fiscal Year: 2003
    ..The position of the investigators is that this study will provide definitive evidence that the TDH is incorrect and that a more complex model of the functional neuroanatomy of syntactic processing is needed. ..
  4. FUNCTIONAL NEUROIMAGING STUDIES OF SYNTACTIC PROCESSING
    David Caplan; Fiscal Year: 2005
    ..The proposed research will increase our knowledge of the neural basis of syntactic processing in sentence comprehension, extending the current database to previously unstudied syntactic operations and populations. ..
  5. Disorders of Syntactic Comprehension
    David Caplan; Fiscal Year: 2007
    ..The results could have important consequences for how we think of these disorders and the neural organization that supports these functions. ..
  6. FUNCTIONAL NEUROIMAGING STUDIES OF SYNTACTIC PROCESSING
    David Caplan; Fiscal Year: 2003
    ..The proposed research will increase our knowledge of the neural basis of syntactic processing in sentence comprehension, extending the current database to previously unstudied syntactic operations and populations. ..
  7. FUNCTIONAL NEUROIMAGING STUDIES OF SYNTACTIC PROCESSING
    David Caplan; Fiscal Year: 2004
    ..The proposed research will increase our knowledge of the neural basis of syntactic processing in sentence comprehension, extending the current database to previously unstudied syntactic operations and populations. ..
  8. Disorders of Syntactic Comprehension
    David Caplan; Fiscal Year: 2009
    ..The results could have important consequences for howwe think of these disorders and the neural organization that supports these functions. ..
  9. Functional Neuroimaging Studies of Syntactic Comprehension
    David Caplan; Fiscal Year: 2009
    ....
  10. Disorders of Syntactic Comprehension
    DAVID NORMAN CAPLAN; Fiscal Year: 2010
    ..The results could have important consequences for howwe think of these disorders and the neural organization that supports these functions. ..
  11. Disorders of Syntactic Comprehension
    David Caplan; Fiscal Year: 2009
    ..The results could have important consequences for howwe think of these disorders and the neural organization that supports these functions. ..
  12. Spatiotemporal Neuroimaging of Situated Sentence Comprehension
    DAVID NORMAN CAPLAN; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: The project will advance our understanding of the complex neural activities that occur during sentence comprehension. As such, the findings will provide a basis for better diagnosis of such disorders. ..
  13. Sources of rCBF Effects in Syntactic Comprehension
    David Caplan; Fiscal Year: 2003
    ..2. These changes are due to differences in the use of visual mental images and short-term memory in performing the sentence comprehension task in different groups of subjects. ..
  14. AN INVESTIGATION OF THE TRACE DELETION HYPOTHESIS
    David Caplan; Fiscal Year: 2002
    ..The position of the investigators is that this study will provide definitive evidence that the TDH is incorrect and that a more complex model of the functional neuroanatomy of syntactic processing is needed. ..
  15. LOCALIZATION OF DISORDERS OF SYNTAX-BASED COMPREHENSION
    David Caplan; Fiscal Year: 1999
    ..The data will provide important new knowledge about the location of lesions that produce these deficits, and will be relevant to models of the functional neuroanatomy of this aspect of language processing. ..
  16. FRACTIONATION OF DISORDERS OF SENTENCE COMPREHENSION
    David Caplan; Fiscal Year: 1992
    ..The results will also be of use in clinical patient diagnosis and in planning therapy...
  17. FRACTIONATION OF DISORDERS OF SENTENCE COMPREHENSION
    David Caplan; Fiscal Year: 1993
    ..The results will also be of use in clinical patient diagnosis and in planning therapy...
  18. LOCALIZATION OF DISORDERS OF SYNTAX-BASED COMPREHENSION
    David Caplan; Fiscal Year: 2000
    ..The data will provide important new knowledge about the location of lesions that produce these deficits, and will be relevant to models of the functional neuroanatomy of this aspect of language processing. ..
  19. AN INVESTIGATION OF THE TRACE DELETION HYPOTHESIS
    David Caplan; Fiscal Year: 2000
    ..The position of the investigators is that this study will provide definitive evidence that the TDH is incorrect and that a more complex model of the functional neuroanatomy of syntactic processing is needed. ..
  20. FUNCTIONAL NEUROIMAGING STUDIES OF SYNTACTIC PROCESSING
    David Caplan; Fiscal Year: 2001
    ..The proposed research will increase our knowledge of the neural basis of syntactic processing in sentence comprehension, extending the current database to previously unstudied syntactic operations and populations. ..
  21. LOCALIZATION OF DISORDERS OF SYNTAX-BASED COMPREHENSION
    David Caplan; Fiscal Year: 2001
    ..The data will provide important new knowledge about the location of lesions that produce these deficits, and will be relevant to models of the functional neuroanatomy of this aspect of language processing. ..
  22. AN INVESTIGATION OF THE TRACE DELETION HYPOTHESIS
    David Caplan; Fiscal Year: 2001
    ..The position of the investigators is that this study will provide definitive evidence that the TDH is incorrect and that a more complex model of the functional neuroanatomy of syntactic processing is needed. ..
  23. FUNCTIONAL NEUROIMAGING STUDIES OF SYNTACTIC PROCESSING
    David Caplan; Fiscal Year: 2002
    ..The proposed research will increase our knowledge of the neural basis of syntactic processing in sentence comprehension, extending the current database to previously unstudied syntactic operations and populations. ..
  24. Disorders of Syntactic Comprehension
    DAVID NORMAN CAPLAN; Fiscal Year: 2011
    ..The results could have important consequences for howwe think of these disorders and the neural organization that supports these functions. ..