Fernando D Camargo

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. ncbi YAP1 increases organ size and expands undifferentiated progenitor cells
    Fernando D Camargo
    Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, Massachusetts 02142, USA
    Curr Biol 17:2054-60. 2007
  2. ncbi Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
    Jonathan B Johnnidis
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Nature 451:1125-9. 2008
  3. ncbi Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c
    Sandra Stehling-Sun
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Nat Immunol 10:289-96. 2009
  4. ncbi The impact of microRNAs on protein output
    Daehyun Baek
    Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA
    Nature 455:64-71. 2008
  5. ncbi Generation of iPSCs from cultured human malignant cells
    Jan E Carette
    Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
    Blood 115:4039-42. 2010
  6. ncbi Oct4 expression is not required for mouse somatic stem cell self-renewal
    Christopher J Lengner
    Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Nine Cambridge Center, Cambridge, MA 02142, USA
    Cell Stem Cell 1:403-15. 2007
  7. ncbi Isolation and functional characterization of side population stem cells
    Jonathan B Johnnidis
    Whitehead Institute for Biomedical Research, Cambridge, MA, USA
    Methods Mol Biol 430:183-93. 2008
  8. ncbi Yap1 acts downstream of α-catenin to control epidermal proliferation
    Karin Schlegelmilch
    Stem Cell Program, Children s Hospital, Boston, MA 02115, USA
    Cell 144:782-95. 2011
  9. ncbi Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners
    Fernando D Camargo
    Center for Cell and Gene Therapy, Baylor College of Medicinem Houston, Texas 77098, USA
    J Clin Invest 113:1266-70. 2004
  10. ncbi Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates
    Fernando D Camargo
    Center for Cell and Gene Therapy, Baylor College of Medicine, One Baylor Plaza, BCM505, Houston, Texas 77030, USA
    Nat Med 9:1520-7. 2003

Collaborators

  • Rudolf Jaenisch
  • Mark D Fleming
  • Stephen L Nutt
  • Konrad Hochedlinger
  • Chanseok Shin
  • Oktay Kirak
  • Margaret Goodell
  • Jonathan B Johnnidis
  • Thijn R Brummelkamp
  • Sandra Stehling-Sun
  • Karin Schlegelmilch
  • Jan Pruszak
  • Jan E Carette
  • Sumita Gokhale
  • Daehyun Baek
  • Christopher J Lengner
  • Shannon L McKinney-Freeman
  • Morvarid Mohseni
  • Dawang Zhou
  • Bridget T Kreger
  • Joseph Avruch
  • Valera Vasioukhin
  • J Renato Rodriguez
  • Vincent A Blomen
  • Marius Wernig
  • Malini Varadarajan
  • Jessica Dade
  • Rodney P DeKoter
  • David P Bartel
  • Steven P Gygi
  • Marian H Harris
  • Judit Villen
  • Michael H Lam
  • Robert T Wheeler
  • Hans R Scholer
  • Samir Zaidi
  • G Grant Welstead
  • Alexey Tomilin
  • Fulvio Mavilio
  • Giuliana Ferrari
  • Kathyjo A Jackson

Detail Information

Publications11

  1. ncbi YAP1 increases organ size and expands undifferentiated progenitor cells
    Fernando D Camargo
    Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, Massachusetts 02142, USA
    Curr Biol 17:2054-60. 2007
    ..Our data show that the Hippo signaling pathway regulates organ size in mammals and can act on stem cell compartments, indicating a potential link between stem/progenitor cells, organ size, and cancer...
  2. ncbi Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
    Jonathan B Johnnidis
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Nature 451:1125-9. 2008
    ..Our data support a model in which miR-223 acts as a fine-tuner of granulocyte production and the inflammatory response...
  3. ncbi Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c
    Sandra Stehling-Sun
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Nat Immunol 10:289-96. 2009
    ..1 during lymphopoiesis. Thus, Mef2c is a crucial component of the transcriptional network that regulates cell fate 'choice' in multipotent progenitors...
  4. ncbi The impact of microRNAs on protein output
    Daehyun Baek
    Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA
    Nature 455:64-71. 2008
    ..The impact of microRNAs on the proteome indicated that for most interactions microRNAs act as rheostats to make fine-scale adjustments to protein output...
  5. ncbi Generation of iPSCs from cultured human malignant cells
    Jan E Carette
    Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
    Blood 115:4039-42. 2010
    ..This finding indicates that the therapeutic agent imatinib targets cells in a specific epigenetic differentiated cell state, and this may contribute to its inability to fully eradicate disease in chronic myeloid leukemia patients...
  6. ncbi Oct4 expression is not required for mouse somatic stem cell self-renewal
    Christopher J Lengner
    Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Nine Cambridge Center, Cambridge, MA 02142, USA
    Cell Stem Cell 1:403-15. 2007
    ..Oct4 gene ablation in these tissues revealed no abnormalities in homeostasis or regenerative capacity. We conclude that Oct4 is dispensable for both self-renewal and maintenance of somatic stem cells in the adult mammal...
  7. ncbi Isolation and functional characterization of side population stem cells
    Jonathan B Johnnidis
    Whitehead Institute for Biomedical Research, Cambridge, MA, USA
    Methods Mol Biol 430:183-93. 2008
    ..In this chapter, we describe a protocol to reproducibly isolate murine BM SP cells, as well as analytic measures, such as single cell transplantation, that can be used to assess the functionality of SP-derived stem cells...
  8. ncbi Yap1 acts downstream of α-catenin to control epidermal proliferation
    Karin Schlegelmilch
    Stem Cell Program, Children s Hospital, Boston, MA 02115, USA
    Cell 144:782-95. 2011
    ..Together, these data identify Yap1 as a determinant of the proliferative capacity of epidermal stem cells and as an important effector of a "crowd control" molecular circuitry in mammalian skin...
  9. ncbi Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners
    Fernando D Camargo
    Center for Cell and Gene Therapy, Baylor College of Medicinem Houston, Texas 77098, USA
    J Clin Invest 113:1266-70. 2004
    ..Our findings raise the possibility that differentiated myeloid cells may be useful for future therapeutic applications of in vivo cellular fusion...
  10. ncbi Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates
    Fernando D Camargo
    Center for Cell and Gene Therapy, Baylor College of Medicine, One Baylor Plaza, BCM505, Houston, Texas 77030, USA
    Nat Med 9:1520-7. 2003
    ..Our results indicate that circulating myeloid cells, in response to inflammatory cues, migrate to regenerating skeletal muscle and stochastically incorporate into mature myofibers...
  11. ncbi Muscle-derived hematopoietic stem cells are hematopoietic in origin
    Shannon L McKinney-Freeman
    Department of Pediatrics, Center for Cell and Gene Therapy, BCM 505, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 99:1341-6. 2002
    ..Although CD45-negative cells were highly myogenic in vitro and in vivo, CD45-positive muscle-derived cells displayed only very limited myogenic activity and only in vivo...