William-R Brugge

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi Diagnosis and management of relapsing pancreatitis associated with cystic neoplasms of the pancreas
    William R Brugge
    GI Endoscopy Unit, Blake 452c, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, United States
    World J Gastroenterol 14:1038-43. 2008
  2. ncbi Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study
    William R Brugge
    Gastrointestinal Unit, Department of Surgery, Massachusetts General Hospital, Blake 4, 55 Fruit Street, Boston, MA 02114, USA
    Gastroenterology 126:1330-6. 2004
  3. ncbi Pancreatic fine needle aspiration: to do or not to do?
    William R Brugge
    GI Unit, Massachusetts General Hospital. Boston, MA 02114, USA
    JOP 5:282-8. 2004
  4. ncbi Cystic neoplasms of the pancreas
    William R Brugge
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    N Engl J Med 351:1218-26. 2004
  5. ncbi The incidental pancreatic cyst on abdominal computerized tomography imaging: diagnosis and management
    William R Brugge
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Gastroenterol Hepatol 6:140-4. 2008
  6. ncbi Management and outcomes of pancreatic cystic lesions
    W R Brugge
    GI Unit Blake 4, Massachusetts General Hospital, Boston, MA, United States
    Dig Liver Dis 40:854-9. 2008
  7. ncbi Advances in the endoscopic management of patients with pancreatic and biliary malignancies
    William R Brugge
    GI Unit, Blake 452c, Massachusetts General Hospital, Boston, MA 02114, USA
    South Med J 99:1358-66. 2006
  8. ncbi Approach to cystic pancreatic lesions
    William R Brugge
    Massachusetts General Hospital, Gastrointestinal Unit, Blake 4, Boston, 02114, USA
    Gastrointest Endosc Clin N Am 15:485-96, viii. 2005
  9. ncbi Endoscopic techniques to diagnose and manage biliary tumors
    William R Brugge
    Gastrointestinal Endoscopy Unit, Massachusetts General Hospital, Blake 452c, Boston, MA 02114, USA
    J Clin Oncol 23:4561-5. 2005
  10. ncbi Role of endoscopic ultrasound in the diagnosis of cystic lesions of the pancreas
    W R Brugge
    Massachusetts General Hospital, GI Unit Blake 452c, Boston, MA 02114, USA
    Pancreatology 1:637-40. 2001

Collaborators

Detail Information

Publications78

  1. ncbi Diagnosis and management of relapsing pancreatitis associated with cystic neoplasms of the pancreas
    William R Brugge
    GI Endoscopy Unit, Blake 452c, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, United States
    World J Gastroenterol 14:1038-43. 2008
    ..Management of these patients consists of surgical resection and monitoring in patients not able to withstand surgery...
  2. ncbi Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study
    William R Brugge
    Gastrointestinal Unit, Department of Surgery, Massachusetts General Hospital, Blake 4, 55 Fruit Street, Boston, MA 02114, USA
    Gastroenterology 126:1330-6. 2004
    ..The purpose of this investigation was to determine the most accurate test for differentiating mucinous from nonmucinous cystic lesions...
  3. ncbi Pancreatic fine needle aspiration: to do or not to do?
    William R Brugge
    GI Unit, Massachusetts General Hospital. Boston, MA 02114, USA
    JOP 5:282-8. 2004
  4. ncbi Cystic neoplasms of the pancreas
    William R Brugge
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    N Engl J Med 351:1218-26. 2004
  5. ncbi The incidental pancreatic cyst on abdominal computerized tomography imaging: diagnosis and management
    William R Brugge
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Gastroenterol Hepatol 6:140-4. 2008
  6. ncbi Management and outcomes of pancreatic cystic lesions
    W R Brugge
    GI Unit Blake 4, Massachusetts General Hospital, Boston, MA, United States
    Dig Liver Dis 40:854-9. 2008
    ..Pancreatitis is rarely observed clinically and is not present in resection specimens. A randomised prospective clinical trial is currently underway...
  7. ncbi Advances in the endoscopic management of patients with pancreatic and biliary malignancies
    William R Brugge
    GI Unit, Blake 452c, Massachusetts General Hospital, Boston, MA 02114, USA
    South Med J 99:1358-66. 2006
    ..The endoscopic therapy for pancreatic-biliary malignancy involves the use of stenting which relieves the biliary obstruction commonly seen in these patients...
  8. ncbi Approach to cystic pancreatic lesions
    William R Brugge
    Massachusetts General Hospital, Gastrointestinal Unit, Blake 4, Boston, 02114, USA
    Gastrointest Endosc Clin N Am 15:485-96, viii. 2005
    ..With the greater use of cross-sectional imaging, an increasing number of these neoplasms are being seen...
  9. ncbi Endoscopic techniques to diagnose and manage biliary tumors
    William R Brugge
    Gastrointestinal Endoscopy Unit, Massachusetts General Hospital, Blake 452c, Boston, MA 02114, USA
    J Clin Oncol 23:4561-5. 2005
    ..In the future, molecular markers will be employed to improve the sensitivity for the detection of malignancy in bile duct samples obtained through brushing, aspiration, and biopsy...
  10. ncbi Role of endoscopic ultrasound in the diagnosis of cystic lesions of the pancreas
    W R Brugge
    Massachusetts General Hospital, GI Unit Blake 452c, Boston, MA 02114, USA
    Pancreatology 1:637-40. 2001
    ..Through the use of these techniques, the ability to detect and diagnose early malignancies of the pancreas will be greatly enhanced...
  11. ncbi Serous cystadenoma of the pancreas: limitations and pitfalls of endoscopic ultrasound-guided fine-needle aspiration biopsy
    Nicole A Belsley
    Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Cancer 114:102-10. 2008
    ..In the current study, the authors evaluated the diagnostic sensitivity of endoscopic ultrasound (EUS)-guided fine-needle aspiration biopsy (FNAB) and cross-sectional imaging for SCA...
  12. ncbi Evaluation of pancreatic cystic lesions with EUS
    William R Brugge
    GI Endoscopy Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Gastrointest Endosc 59:698-707. 2004
  13. ncbi Concentration-dependent ablation of pancreatic tissue by EUS-guided ethanol injection
    Kai Matthes
    Gastrointestinal Unit, Gastrointestinal Pathology Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Gastrointest Endosc 65:272-7. 2007
    ..Ethanol is a commonly available agent and has been used to successfully and safely ablate cystic lesions of various organs...
  14. ncbi Approach to pancreatic cystic lesions
    Bhavani Moparty
    Massachusetts General Hospital, Blake 452 C, 55 Fruit Street, Boston, MA 02144, USA
    Curr Gastroenterol Rep 9:130-5. 2007
    ..In this review, we summarize the recent publications that have examined the key issues in the diagnosis and management of cystic lesions of the pancreas...
  15. ncbi Pancreatic cystic lesions: when to watch, when to operate, and when to ignore
    Brian G Turner
    Massachusetts General Hospital, Gastroenterology Unit, 55 Fruit Street, Boston, MA 02114, USA
    Curr Gastroenterol Rep 12:98-105. 2010
    ..This article reviews current guidelines for the evaluation of pancreatic cystic lesions, underscores the challenges posed by these lesions, and discusses current and future studies that will aid in patient management...
  16. ncbi EUS-guided photodynamic therapy with verteporfin for ablation of normal pancreatic tissue: a pilot study in a porcine model (with video)
    Tony E Yusuf
    GI Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Gastrointest Endosc 67:957-61. 2008
    ..EUS-guided photodynamic therapy (PDT) with the photosensitizing agent porfimer sodium has been shown to be effective in ablation of pancreatic tissue...
  17. ncbi Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 35-2003. A 75-year-old man with a cystic lesion of the pancreas
    Andrew L Warshaw
    Department of Surgery, Massachusetts General Hospital and Harvard Medical School, USA
    N Engl J Med 349:1954-61. 2003
  18. ncbi Effect of tumor characteristics and duplication of the muscularis mucosae on the endoscopic staging of superficial Barrett esophagus-related neoplasia
    Rajni V Mandal
    Department of Pathology, Gastrointestinal Pathology Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 33:620-5. 2009
    ..EUS alone is not sufficient for staging these neoplasms precisely, and to accurately stratify patients into different treatment arms, EMR should play a role as a complementary staging modality...
  19. ncbi Case records of the Massachusetts General Hospital. Case 20-2005. A 58-year-old man with locally advanced pancreatic cancer
    David P Ryan
    Department of Hematology and Oncology, Massachusetts General Hospital, Boston, USA
    N Engl J Med 352:2734-41. 2005
  20. ncbi EUS staging of upper GI malignancies: results of a prospective randomized trial
    Kai Matthes
    Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Gastrointest Endosc 64:496-502. 2006
    ..However, the number of abnormal lymph nodes detected by TA-EUS was more than by L-EUS. These findings suggest that radial or transverse-array EUS imaging should be the primary method for staging of UGI malignancies...
  21. ncbi Endoscopic mucosal resection: an improved diagnostic procedure for early gastroesophageal epithelial neoplasms
    Mindy J Hull
    Department of Pathology, Gastrointestinal Pathology Service, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Am J Surg Pathol 30:114-8. 2006
    ..EMR can substantially modify the diagnostic grade of a lesion and therefore facilitate optimal therapeutic decisions by avoiding undertreatment and overtreatment based on inaccurate grading and staging...
  22. ncbi Feasibility of endoscopic transgastric distal pancreatectomy in a porcine animal model
    Kai Matthes
    Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Gastrointest Endosc 66:762-6. 2007
    ..In contrast to laparoscopic tubal ligation, oophorectomy, and appendectomy, laparoscopic distal pancreatectomy is associated with a morbidity rate of more than 50% and a mortality rate of more than 3%...
  23. ncbi Radiology of pancreatic adenocarcinoma: current status of imaging
    Dushyant V Sahani
    Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Gastroenterol Hepatol 23:23-33. 2008
    ..Each of these modalities has its peculiar strengths and weaknesses...
  24. ncbi Intraductal papillary mucinous neoplasm of the pancreas: cytologic features predict histologic grade
    Paul J Michaels
    James Homer Wright Pathology Laboratories and Cytopathology Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Cancer 108:163-73. 2006
    ..Necrosis was the only feature found to be strongly suggestive of invasion...
  25. ncbi High-grade atypical epithelial cells in pancreatic mucinous cysts are a more accurate predictor of malignancy than "positive" cytology
    Martha Bishop Pitman
    Department of Pathology, The James Homer Wright Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Cancer Cytopathol 118:434-40. 2010
    ..In the current study, the authors hypothesized that a cytological threshold of high-grade atypical epithelial cells (AEC) is a more accurate predictor of malignancy...
  26. ncbi Cytological and cyst fluid analysis of small (< or =3 cm) branch duct intraductal papillary mucinous neoplasms adds value to patient management decisions
    Martha Bishop Pitman
    James Homer Wright Pathology Laboratories and Cytopathology Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Pancreatology 8:277-84. 2008
    ..The aim of our study was to compare this proposed algorithm to one that incorporates cytology with less than malignant epithelial cells and cyst fluid carcinoembryonic antigen (CEA)...
  27. ncbi Survival study of natural orifice translumenal endoscopic surgery for rectosigmoid resection using transanal endoscopic microsurgery with or without transgastric endoscopic assistance in a swine model
    Patricia Sylla
    Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 15 Parkman Street, WACC 460, Boston, MA 02114, USA
    Surg Endosc 24:2022-30. 2010
    ....
  28. ncbi Reducing the unexpectedly high rate of injuries caused by NOTES gastrotomy creation
    Dae Kyung Sohn
    Department of Surgery, Massachusetts General Hospital, Harvard Medical School, WACC 460, Boston, MA 02114, USA
    Surg Endosc 24:277-82. 2010
    ..This study was conducted to identify the incidence and types of complications related to gastrotomy creation with the needle knife puncture and balloon dilatation technique for NOTES access to the peritoneal cavity...
  29. ncbi Role of computed tomography perfusion in the evaluation of pancreatic necrosis and pancreatitis after endoscopic ultrasound-guided ablation of the pancreas in a porcine model
    Dushyant V Sahani
    Department of Radiology, Massachusetts General Hospital, Boston, 02114, USA
    Pancreas 38:775-81. 2009
    ..To evaluate the role of computed tomography (CT) perfusion in detection of pancreatic necrosis and pancreatitis after endoscopic ultrasound-guided ethanol ablation of porcine pancreas and to correlate the evaluation with histopathology...
  30. ncbi Current trends in pancreatic cystic neoplasms
    Cristina R Ferrone
    Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
    Arch Surg 144:448-54. 2009
    ..To define how patients with pancreatic cysts are being diagnosed and treated...
  31. ncbi Molecular analysis of pancreatic cyst fluid: a comparative analysis with current practice of diagnosis
    Jian Shen
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Cancer 117:217-27. 2009
    ....
  32. ncbi Novel endoscopic therapeutic modalities for superficial neoplasms arising in Barrett's esophagus: a primer for surgical pathologists
    Gregory Y Lauwers
    Gastrointestinal Pathology Unit, Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114 USA
    Mod Pathol 22:489-98. 2009
    ....
  33. ncbi Multidisciplinary approach to diagnosis and management of intraductal papillary mucinous neoplasms of the pancreas
    Dushyant V Sahani
    Department of Radiology, Division of Abdominal Imaging and Intervention, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Clin Gastroenterol Hepatol 7:259-69. 2009
    ..Furthermore, issues of multifocality and increased predisposition of the pancreas to ductal adenocarcinoma must be addressed at follow-up evaluation. A follow-up management algorithm also is proposed in this review...
  34. ncbi En bloc esophageal mucosectomy for concentric circumferential mucosal resection (with video)
    Field F Willingham
    Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Gastrointest Endosc 69:147-51. 2009
    ..With conventional EMR, specimens are fragmented, metaplasia may be left behind, and invasive lesions could be missed because of incomplete sampling. Concentric subtotal esophageal mucosectomy would address these limitations...
  35. ncbi IgG4+ to IgG+ plasma cells ratio of ampulla can help differentiate autoimmune pancreatitis from other "mass forming" pancreatic lesions
    Alireza Sepehr
    Department of Pathology, Gastrointestinal Pathology Service, Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 32:1770-9. 2008
    ..In conclusion, evaluation of ampullary histology and IgG4/IgG ratio might be proven beneficial in discriminating AIP from other mass forming pancreatic lesions...
  36. ncbi NOTES rectosigmoid resection using transanal endoscopic microsurgery (TEM) with transgastric endoscopic assistance: a pilot study in swine
    Patricia Sylla
    Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    J Gastrointest Surg 12:1717-23. 2008
    ..After maximal sigmoid mobilization, the specimen was exteriorized and transected, and the proximal colon was stapled to the distal rectum. In a subset of animals, transgastric endoscopic access was used to mobilize the colon further...
  37. ncbi Autoimmune pancreatitis
    Dmitry L Finkelberg
    Department of Medicine (Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    N Engl J Med 355:2670-6. 2006
  38. ncbi EUS-guided injection of paclitaxel (OncoGel) provides therapeutic drug concentrations in the porcine pancreas (with video)
    Kai Matthes
    Gastrointestinal Unit, Gastrointestinal Pathology Service, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Gastrointest Endosc 65:448-53. 2007
    ..OncoGel (ReGel/paclitaxel) is an intralesional injectable formulation of the chemotherapeutic drug, paclitaxel, for local tumor management...
  39. ncbi EUS-guided fine needle aspiration of pancreatic cysts: a retrospective analysis of complications and their predictors
    Linda S Lee
    Gastroenterology Division, Brigham and Women's Hospital, 75 Francis Street, Boston, Massachusetts 02115, USA
    Clin Gastroenterol Hepatol 3:231-6. 2005
    ..CONCLUSIONS: EUS-guided pancreatic cyst aspiration carries a low complication rate similar to that reported for solid pancreatic lesions. No patient or cyst characteristics appear to be predictive of adverse events...
  40. ncbi Endoscopic ultrasound guided fine needle aspiration biopsy of autoimmune pancreatitis: diagnostic criteria and pitfalls
    Vikram Deshpande
    Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
    Am J Surg Pathol 29:1464-71. 2005
    ....
  41. ncbi Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 8-2004. A 28-year-old man with abdominal pain, fever, and a mass in the region of the pancreas
    William R Brugge
    Gastroenterology Unit, Department of Medicine, Massachusetts General Hospital, USA
    N Engl J Med 350:1131-8. 2004
  42. ncbi Cystic pancreatic lesions: a simple imaging-based classification system for guiding management
    Dushyant V Sahani
    Division of Abdominal Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA
    Radiographics 25:1471-84. 2005
    ..Endoscopic ultrasonography-guided aspiration and biopsy is useful in cases that are indeterminate at cross-sectional imaging or that require observation...
  43. ncbi Endoscopic mucosal resection for gastric epithelial neoplasms: a study of 39 cases with emphasis on the evaluation of specimens and recommendations for optimal pathologic analysis
    Gregory Y Lauwers
    Department of Pathology, Gastrointestinal Pathology Service, Massachusetts General Hospital, Boston, MA 02114, USA
    Mod Pathol 17:2-8. 2004
    ..Based on our experience, we offer some recommendations in order to provide optimal pathologic analysis of endoscopic mucosal resection specimens...
  44. ncbi Pancreatic cysts 3 cm or smaller: how aggressive should treatment be?
    Dushyant V Sahani
    Department of Radiology, Division of Abdominal Imaging, Massachusetts General Hospital, Boston, 02114, USA
    Radiology 238:912-9. 2006
    ....
  45. ncbi Incidental pancreatic cysts: clinicopathologic characteristics and comparison with symptomatic patients
    Carlos Fernandez-del Castillo
    Department of Surgery and Gastroenterology, Massachusetts General Hospital ACC 336, 15 Parkman Street, Boston, MA 02114, USA
    Arch Surg 138:427-3; discussion 433-4. 2003
    ..Widespread use of computed tomography and ultrasound has led to the identification of increasing numbers of patients with asymptomatic cystic lesions of the pancreas...
  46. ncbi Management of superficial Barrett's epithelium-related neoplasms by endoscopic mucosal resection: clinicopathologic analysis of 27 cases
    Mari Mino-Kenudson
    Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 29:680-6. 2005
    ..This is a significant advantage since it can modify patients' management. However, frequent incompleteness of resection and high persistence/recurrence are significant pitfalls that dictate continued endoscopic surveillance...
  47. ncbi Ethanol lavage of pancreatic cystic lesions: initial pilot study
    S Ian Gan
    Gastrointestinal Unit, Department of Pathology, Massachusetts General Hospital, Boston, 02114, USA
    Gastrointest Endosc 61:746-52. 2005
    ..A subset of patients undergoing ethanol lavage appears to have long-term resolution on follow-up imaging. Further prospective studies are required to determine if ethanol lavage is an effective treatment for pancreatic cystic lesions...
  48. ncbi Natural orifice versus conventional laparoscopic distal pancreatectomy in a porcine model: a randomized, controlled trial
    Field F Willingham
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Gastrointest Endosc 70:740-7. 2009
    ..Distal pancreatectomy has significant postoperative morbidity and would permit rigorous examination in a controlled trial setting...
  49. ncbi Diagnosis of pancreatic neoplasia with EUS and FNA: a report of accuracy
    Brian G Turner
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
    Gastrointest Endosc 71:91-8. 2010
    ..EUS-guided FNA has the potential to provide diagnostic cytologic material from pancreatic lesions that are suspicious for malignancy...
  50. ncbi Leaks and endoscopic assessment of break of integrity after NOTES gastrotomy: the LEAKING study, a prospective, randomized, controlled trial
    Field F Willingham
    Department of Medicine, Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Gastrointest Endosc 71:1018-24. 2010
    ..Gastric leak testing after natural orifice transluminal endoscopic surgery (NOTES) gastrotomy closure may help reduce the risk of leaks after transgastric procedures...
  51. ncbi Pancreatic tissue sampling guided by EUS, CT/US, and surgery: a comparison of sensitivity and specificity
    J Shawn Mallery
    Department of Medicine, Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Gastrointest Endosc 56:218-24. 2002
    ..CONCLUSION: EUS-guided tissue sampling of pancreatic masses is as accurate as CT/US-guided sampling and surgical biopsies...
  52. ncbi Autoimmune pancreatitis: a systemic immune complex mediated disease
    Vikram Deshpande
    Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 30:1537-45. 2006
    ..Documentation of increased numbers of tissue IgG4 positive plasma cells, although not an entirely specific marker for AIP, may provide ancillary evidence for the diagnosis of a IgG4-related systemic disease...
  53. ncbi New kid on the block? Autoimmune pancreatitis
    David G Forcione
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    Best Pract Res Clin Anaesthesiol 24:361-78. 2010
    ..Close follow-up for misdiagnosis and relapse. Long term immunomodulatory therapy likely in at least 30%. Pancreatic cancer may be an evolving long term risk of patients with AIP...
  54. ncbi EUS-guided ethanol versus saline solution lavage for pancreatic cysts: a randomized, double-blind study
    John DeWitt
    Department of Gastroenterology and Hepatology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Gastrointest Endosc 70:710-23. 2009
    ..Surgery for pancreatic cysts is associated with significant morbidity. A pilot study previously demonstrated the safety of EUS-guided ethanol lavage of pancreatic cysts...
  55. ncbi Natural orifice transesophageal mediastinoscopy and thoracoscopy: a survival series in swine
    Denise W Gee
    Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Wang Ambulatory Care Center 460, 15 Parkman Street, Boston, MA 02114 3117, USA
    Surg Endosc 22:2117-22. 2008
    ..The purpose of this study was to demonstrate the feasibility of transesophageal natural orifice translumenal endoscopic surgery (NOTES) and to determine the complications that might be seen in surviving animals...
  56. ncbi Feasibility of endoscopic transesophageal thoracic sympathectomy (with video)
    Brian G Turner
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Gastrointest Endosc 71:171-5. 2010
    ..Thoracoscopic sympathectomy is the preferred surgical treatment for patients with disabling palmar hyperhidrosis. Current methods require a transthoracic approach to permit ablation of the thoracic sympathetic chain...
  57. ncbi Gastrointestinal cancer imaging: deeper than the eye can see
    Richard S Kwon
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Gastroenterology 128:1538-53. 2005
  58. ncbi EUS-guided fine-needle aspiration of a renal mass: an alternative method for diagnosis of malignancy
    James J Farrell
    Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Gastrointest Endosc 56:450-2. 2002
  59. ncbi EUS-guided FNA for the diagnosis of GI stromal cell tumors: sensitivity and cytologic yield
    Paul S Sepe
    Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Gastrointest Endosc 70:254-61. 2009
    ..Studies to date evaluating the sensitivity of EUS-FNA for the diagnosis of GI stromal cell tumors (GIST) have been small, and few have relied on surgical histologic diagnosis as the reference standard...
  60. ncbi Endoscopic interventions for weight loss surgery
    James C Ellsmere
    Section of Minimally Invasive Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Obesity (Silver Spring) 17:929-33. 2009
    ..These interventions should be a high priority for development and investigation...
  61. ncbi Endoscopic ultrasound is a sensitive and specific test to diagnose portal venous system thrombosis (PVST)
    Lawrence Lai
    GI Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Am J Gastroenterol 99:40-4. 2004
    ..In an additional group of 11 patients, EUS demonstrated the presence of a PVST that was not detected by CT scanning. CONCLUSION: Linear EUS is a highly sensitive and specific test for PVST...
  62. ncbi The EUS hardware store: state of the art technical review of instruments and equipment (with videos)
    Tony E Yusuf
    GI Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, and Division of Gastroenterology and Hepatology, University of Chicago Hospitals, Chicago, Illinois, USA
    Gastrointest Endosc 66:131-43. 2007
  63. ncbi Optimizing methods for the diagnosis of pancreatic cancer
    William R Brugge
    J Clin Gastroenterol 41:869-70. 2007
  64. ncbi The mistletoe and cyst-fluid analysis: a sticky insight
    William R Brugge
    Gastrointest Endosc 64:703-4. 2006
  65. ncbi Endoscopic diagnosis and treatment of pancreatic cysts
    Shivakumar Vignesh
    Division of Gastroenterology and Hepatology, Penn State College of Medicine, Hershey, PA 17033, USA
    J Clin Gastroenterol 42:493-506. 2008
    ..Endoscopic ultrasound has an important role in the characterization of pancreatic cystic lesions and helps in selection of the optimal treatment modality...
  66. ncbi Should all pancreatic cystic lesions be resected? Cyst-fluid analysis in the differential diagnosis of pancreatic cystic lesions: a meta-analysis
    William R Brugge
    Gastrointest Endosc 62:390-1. 2005
  67. ncbi Cardioembolic stroke in a patient with spindle cell sarcoma of the left atrium
    Davinder S Jassal
    Institute of Cardiovascular Sciences, Division of Cardiology, Department of Cardiac Sciences, St Boniface General Hospital, Winnipeg, Manitoba, Canada
    J Am Soc Echocardiogr 20:438.e1-4. 2007
  68. ncbi Intraductal papillary mucinous tumor of the pancreas
    James J Farrell
    Division of Digestive Diseases, UCLA School of Medicine, Los Angeles, California 90095, USA
    Gastrointest Endosc 55:701-14. 2002
  69. ncbi Fine needle aspiration of pancreatic masses: the clinical impact
    William R Brugge
    Am J Gastroenterol 97:2701-2. 2002
  70. ncbi EUS is an important new tool for accessing the portal vein
    William R Brugge
    Gastrointest Endosc 67:343-4. 2008
  71. ncbi EUS-guided FNA for the diagnosis of gallbladder masses
    Brian C Jacobson
    Section of Gastroenterology, Boston University Medical Center, Massachusetts 02118, USA
    Gastrointest Endosc 57:251-4. 2003
    ..CONCLUSIONS: EUS-guided FNA of gallbladder masses is safe and can provide a definitive diagnosis of malignancy. Gallbladder carcinoma appears endosonographically as a hypoechoic mass and may be associated with focal wall calcifications...
  72. ncbi EUS findings in patients with autoimmune pancreatitis
    James J Farrell
    Division of Digestive Diseases, School of Medicine, UCLA Center for the Health Sciences, University of California-Los Angeles, Los Angeles, CA 90095, USA
    Gastrointest Endosc 60:927-36. 2004
    ..When combined with clinical data, EUS and EUS-guided FNA may support a diagnosis of autoimmune pancreatitis, may warrant a trial of corticosteroid, and thereby may prevent unnecessary surgery...
  73. ncbi Interobserver agreement among endosonographers for the diagnosis of neoplastic versus non-neoplastic pancreatic cystic lesions
    Nuzhat A Ahmad
    Gastroenterology Division, Department of Medicine, Hospital of University of Pennsylvania, Philadelphia VAMC, University of Pennsylvania School of Medicine, 19104-4283, USA
    Gastrointest Endosc 58:59-64. 2003
    ..CONCLUSIONS: There is little more than chance interobserver agreement among experienced endosonographers for diagnosis of neoplastic versus non-neoplastic, specific type, and EUS features of pancreatic cystic lesions...
  74. ncbi Picture imperfect pancreas?
    William R Brugge
    J Clin Gastroenterol 41:3-4. 2007
  75. ncbi Endoscopic mucosal resection using a cap-fitted endoscope improves tissue resection and pathology interpretation: an animal study
    James J Farrell
    Divison of Digestive Diseases, UCLA School of Medicine, 200 UCLA Medical Plaza, Suite 365A, Los Angeles, CA, 90095, USA
    Gastric Cancer 9:3-8. 2006
    ..When possible, EMRC should be the EMR method of choice...
  76. ncbi Endoscopic management of esophageal malignancy: lessons learned from gastric cancer
    William R Brugge
    Curr Opin Gastroenterol 22:527-8. 2006
  77. ncbi New advances in pancreatic imaging
    Richard S Kwon
    Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Curr Opin Gastroenterol 21:561-7. 2005
    ..Improvements in positron emission tomography/computed tomography scans may improve the detection of neuroendocrine tumors. SUMMARY: These new advances will help refine the diagnosis and staging of pancreatic diseases...