H C Breiter
Affiliation: Massachusetts General Hospital
- Microstructural abnormalities in subcortical reward circuitry of subjects with major depressive disorderAnne J Blood
Depression Clinic and Research Program, Mood and Motor Control Laboratory, Addiction Research Program, Laboratory of Neuroimaging and Genetics, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
PLoS ONE 5:e13945. 2010..There has been little investigation in MDD of midbrain and subcortical regions central to reward/aversion function, such as the ventral tegmental area/substantia nigra (VTA/SN), and medial forebrain bundle (MFB)...
- Recurrent, robust and scalable patterns underlie human approach and avoidanceByoung Woo Kim
Motivation and Emotion Neuroscience Collaboration, Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
PLoS ONE 5:e10613. 2010....
- Functional imaging of neural responses to expectancy and experience of monetary gains and lossesH C Breiter
Motivation and Emotion Neuroscience Center, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA
Neuron 30:619-39. 2001..The overlap of the observed activations with those seen previously in response to tactile stimuli, gustatory stimuli, and euphoria-inducing drugs is consistent with a contribution of common circuitry to the processing of diverse rewards...
- Beautiful faces have variable reward value: fMRI and behavioral evidenceI Aharon
Motivation and Emotion Neuroscience Center, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA
Neuron 32:537-51. 2001..An extended set of subcortical and paralimbic reward regions also appear to follow aspects of the keypress rather than the rating procedures, suggesting that reward circuitry function does not include aesthetic assessment...
- A functional magnetic resonance imaging study of auditory vigilance with low and high information processing demandsL J Seidman
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
Neuropsychology 12:505-18. 1998..Performance and degree of activation was associated with an estimate of IQ. Further research should clarify the contributions of working memory and interference filtering to the activated network...
- BDNF, relative preference, and reward circuitry responses to emotional communicationG P Gasic
Motivation and Emotion Neuroscience Collaboration MENC, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Med Genet B Neuropsychiatr Genet 150:762-81. 2009..This study demonstrates that functional allelic variation in BDNF modulates human brain circuits processing reward/aversion information and relative preference transactions...
- Reward circuitry activation by noxious thermal stimuliL Becerra
Center for Functional Pain Neuroimaging and Therapy Research, Boston, MA 02129, USA
Neuron 32:927-46. 2001..These data support the notion that there may be a shared neural system for evaluation of aversive and rewarding stimuli...
- Striatal recruitment during an implicit sequence learning task as measured by functional magnetic resonance imagingS L Rauch
Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
Hum Brain Mapp 5:124-32. 1997..In particular, results from individual subjects suggest that, during the SRT, the reaction time advantage garnered via implicit sequence learning might be predominantly associated with activity within the putamen...
- Functional magnetic resonance imaging of brain reward circuitry in the humanH C Breiter
Department of Radiology, Massachusetts General Hospital, Boston, USA
Ann N Y Acad Sci 877:523-47. 1999..Further work is warranted to test hypothesized functions for all regions within the extended amygdala and integrate them toward an understanding of motivated behavior...
- fMRI of sensitization to angry facesM M Strauss
Motivation and Emotion Neuroscience Collaboration, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, 02129, USA
Neuroimage 26:389-413. 2005..Together these data argue that angry faces, a directly aversive stimulus, produce a sensitization response...
- Acute cortisol administration triggers craving in individuals with cocaine dependenceIgor Elman
Behavioral Psychopharmacology Research Laboratory, Harvard Medical School McLean Hospital, Belmont, MA 02478, USA
Psychopharmacol Bull 37:84-9. 2003..These pilot data suggest that cortisol can induce a state that is associated with drug abuse...
- Cortical thickness abnormalities in cocaine addiction--a reflection of both drug use and a pre-existing disposition to drug abuse?Nikos Makris
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Neuron 60:174-88. 2008..These observations suggest that brain structure abnormalities in addicts are related in part to drug use and in part to predisposition toward addiction...
- Decreased absolute amygdala volume in cocaine addictsNikos Makris
Motivation and Emotion Neuroscience Collaboration, Department of Radiology, Harvard Medical School, Boston, MA 02129, USA
Neuron 44:729-40. 2004..These findings argue for a condition that predisposes the individual to cocaine dependence by affecting the amygdala, or a primary event early in the course of cocaine use...
- Cocaine-primed craving and its relationship to depressive symptomatology in individuals with cocaine dependenceIgor Elman
Department of Psychiatry, Motivation and Emotion Neuroscience Center, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
J Psychopharmacol 16:163-7. 2002....
- Amygdala volume associated with alcohol abuse relapse and cravingJana Wrase
Department of Psychiatry, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
Am J Psychiatry 165:1179-84. 2008..This study sought an association in alcohol-dependent subjects between volumes of reward-related brain regions, alcohol craving, and the risk of relapse...
- COCAINE ADDICTION -- ALTERATIONS IN REWARD CIRCUITRYHans Breiter; Fiscal Year: 2005....