Nada N Boustany

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. pmc Calcium-induced alterations in mitochondrial morphology quantified in situ with optical scatter imaging
    Nada N Boustany
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Biophys J 83:1691-700. 2002
  2. ncbi request reprint Highly sensitive size discrimination of sub-micron objects using optical Fourier processing based on two-dimensional Gabor filters
    Robert M Pasternack
    Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey 08854, USA
    Opt Express 17:12001-12. 2009
  3. doi request reprint Optical Scatter Imaging with a digital micromirror device
    Jing Yi Zheng
    Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08854, USA
    Opt Express 17:20401-14. 2009
  4. doi request reprint Detection of mitochondrial fission with orientation-dependent optical Fourier filters
    Robert M Pasternack
    Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08854, USA
    Cytometry A 79:137-48. 2011
  5. doi request reprint Alterations in the characteristic size distributions of subcellular scatterers at the onset of apoptosis: effect of Bcl-xL and Bax/Bak
    Jing Yi Zheng
    Rutgers University, Department of Biomedical Engineering, Piscataway, New Jersey 08854, USA
    J Biomed Opt 15:045002. 2010
  6. pmc The C-terminal transmembrane domain of Bcl-xL mediates changes in mitochondrial morphology
    Jing Yi Zheng
    Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey, USA
    Biophys J 94:286-97. 2008
  7. pmc Microscopic imaging and spectroscopy with scattered light
    Nada N Boustany
    Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey 08854, USA
    Annu Rev Biomed Eng 12:285-314. 2010
  8. pmc BCL-xL-dependent light scattering by apoptotic cells
    Nada N Boustany
    Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey 08854, USA
    Biophys J 87:4163-71. 2004
  9. pmc Measurement of subcellular texture by optical Gabor-like filtering with a digital micromirror device
    Robert M Pasternack
    Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08854, USA
    Opt Lett 33:2209-11. 2008

Collaborators

Detail Information

Publications9

  1. pmc Calcium-induced alterations in mitochondrial morphology quantified in situ with optical scatter imaging
    Nada N Boustany
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Biophys J 83:1691-700. 2002
    ..Our data show that changes in OSIR correlate with mitochondrial morphology change in situ. OSI provides a new tool for subcellular imaging and complements other microscopy methods, such as fluorescence...
  2. ncbi request reprint Highly sensitive size discrimination of sub-micron objects using optical Fourier processing based on two-dimensional Gabor filters
    Robert M Pasternack
    Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey 08854, USA
    Opt Express 17:12001-12. 2009
    ..46 microm-1 microm and does not rely on a predictive scatter model such as Mie theory. The technique may have applications in high throughput optical analysis of subcellular morphology to study organelle function in living cells...
  3. doi request reprint Optical Scatter Imaging with a digital micromirror device
    Jing Yi Zheng
    Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08854, USA
    Opt Express 17:20401-14. 2009
    ..This improved OSI system could be further developed to automate morphological quantification and sorting of non-spherical particles in situ...
  4. doi request reprint Detection of mitochondrial fission with orientation-dependent optical Fourier filters
    Robert M Pasternack
    Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08854, USA
    Cytometry A 79:137-48. 2011
    ..These results provide strong evidence that the optical Gabor responses track mitochondrial fission during apoptosis and can be used to provide label-free, rapid monitoring of this morphological process within single cells...
  5. doi request reprint Alterations in the characteristic size distributions of subcellular scatterers at the onset of apoptosis: effect of Bcl-xL and Bax/Bak
    Jing Yi Zheng
    Rutgers University, Department of Biomedical Engineering, Piscataway, New Jersey 08854, USA
    J Biomed Opt 15:045002. 2010
    ..Mitochondrial localization of YFP-Bcl-x(L) and the finding that micron-sized particles give rise to the scattering signal further suggest that alterations in mitochondrial morphology may underlie the observed changes in light scattering...
  6. pmc The C-terminal transmembrane domain of Bcl-xL mediates changes in mitochondrial morphology
    Jing Yi Zheng
    Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey, USA
    Biophys J 94:286-97. 2008
    ..Taken together, our results suggest the existence of a secondary Bcl-x(L) function that is mediated by the transmembrane domain, alters mitochondrial morphology, and is distinct from BH3 domain sequestration...
  7. pmc Microscopic imaging and spectroscopy with scattered light
    Nada N Boustany
    Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey 08854, USA
    Annu Rev Biomed Eng 12:285-314. 2010
    ....
  8. pmc BCL-xL-dependent light scattering by apoptotic cells
    Nada N Boustany
    Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey 08854, USA
    Biophys J 87:4163-71. 2004
    ....
  9. pmc Measurement of subcellular texture by optical Gabor-like filtering with a digital micromirror device
    Robert M Pasternack
    Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08854, USA
    Opt Lett 33:2209-11. 2008
    ....