Affiliation: Massachusetts General Hospital
- Endotracheal tubes coated with antiseptics decrease bacterial colonization of the ventilator circuits, lungs, and endotracheal tubeLorenzo Berra
Pulmonary Critical Care Medicine Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Anesthesiology 100:1446-56. 2004....
- Novel system for complete removal of secretions within the endotracheal tube: the Mucus ShaverTheodor Kolobow
Pulmonary-Critical Care Medicine Branch, Section of Pulmonary and Cardiac Assist Devices, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, 20892-1590, USA
Anesthesiology 102:1063-5. 2005
- Antimicrobial-coated endotracheal tubes: an experimental studyLorenzo Berra
Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
Intensive Care Med 34:1020-9. 2008..After 24 h of mechanical ventilation, standard microbiological studies were performed together with scanning electron microscopy and confocal microscopy...
- Alternative approaches to ventilator-associated pneumonia preventionL Berra
Anesthesia and Critical Care Department, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Minerva Anestesiol 77:323-33. 2011..Prevention of VAP cannot be achieved solely by eliminating bacterial biofilm on respiratory devices, and more comprehensive care of the intubated patient needs to be implemented...
- Determinants of tracheostomy decannulation: an international surveyHenry Thomas Stelfox
Department of Critical Care Medicine, University of Calgary, Foothills Medical Centre, EG23A, 1403 29 Street NW, Calgary, AB, Canada, T2N 2T9
Crit Care 12:R26. 2008..Although tracheostomy is probably the most common surgical procedure performed on critically ill patients, it is unknown when a tracheostomy tube can be safely removed...
- A clinical assessment of the Mucus Shaver: a device to keep the endotracheal tube free from secretionsLorenzo Berra
Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
Crit Care Med 40:119-24. 2012..We evaluated a new device designed to clean the endotracheal tube in mechanically ventilated patients, the Mucus Shaver...
- Pseudomonas aeruginosa: acute lung injury or ventilator-associated pneumonia?L Berra
Department of Anesthesia Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Minerva Anestesiol 76:824-32. 2010..aeruginosa that are related to infection, and (III) to illustrate clinical outcomes of ventilated patients with large burdens of P. aeruginosa as well as the mechanism by which this bacterium may evade the host immune response...
- Antibacterial-coated tracheal tubes cleaned with the Mucus Shaver : a novel method to retain long-term bactericidal activity of coated tracheal tubesLorenzo Berra
Massachusetts General Hospital, Department of Anesthesia and Critical Care, Boston MA, USA
Intensive Care Med 32:888-93. 2006..To assess the long-term benefit from antibacterial coatings of the tracheal tube (ETT), and to keep clean the lumen of the ETT...
- Internally coated endotracheal tubes with silver sulfadiazine in polyurethane to prevent bacterial colonization: a clinical trialLorenzo Berra
Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
Intensive Care Med 34:1030-7. 2008..We coated endotracheal tubes (ETT) with silver sulfadiazine (SSD), and tested them in a clinical study to assess the feasibility, safety, and efficacy of preventing bacterial colonization...
- Outcome of patients undergoing prolonged mechanical ventilation after critical illnessLuca M Bigatello
Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Crit Care Med 35:2491-7. 2007..To examine the longitudinal outcome of a cohort of mechanically ventilated patients admitted to an acute care respiratory unit after critical illness...
- Silver-coated endotracheal tubes: is the bactericidal effect time limited?Gianluigi Li Bassi
Crit Care Med 35:986; author reply 987. 2007
- Evaluation of continuous aspiration of subglottic secretion in an in vivo studyLorenzo Berra
Section on Pulmonary and Cardiac Assist Devices, Pulmonary and Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA
Crit Care Med 32:2071-8. 2004..Note that results of studies conducted in an animal model are always difficult to extrapolate to the clinical practice due to anatomical and functional differences...
- Ultrathin-wall, two-stage, twin endotracheal tube: a tracheal tube with minimal resistance and minimal dead space for use in newborn and infant patientsTheodor Kolobow
Pulmonary Critical Care Medicine Branch, Section of Pulmonary and Cardiac Assist Devices, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1434, USA
Pediatr Crit Care Med 5:379-83. 2004..To design and fabricate crush-proof polyurethane tracheal tubes for the newborn with the lowest resistance, least dead space, and thinnest wall...