Research Topics
Genomes and Genes | Attila BecskeiSummaryAffiliation: Massachusetts Institute of Technology Country: USA Publications
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Detail Information
Publications
Quantitative models of nuclear transportAttila Becskei
Department of Physics, Massachusetts Institute of Technology, 13 2009, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
Curr Opin Cell Biol 17:27-34. 2005..Recent evidence suggests that the distinctive kinetics and spatial organization of nuclear transport processes can be used to efficiently propagate signals by new and unexpected pathways...
Contributions of low molecule number and chromosomal positioning to stochastic gene expressionAttila Becskei
Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
Nat Genet 37:937-44. 2005..Transcriptional regulators produced by such random expression propagate noise to their target genes...
Enhancement of cellular memory by reducing stochastic transitionsMurat Acar
Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
Nature 435:228-32. 2005..Indeed, the rate at which single cells randomly switch back and forth between expression states was reduced. These observations provide a quantitative understanding of the stability and reversibility of cellular differentiation states...
A system of counteracting feedback loops regulates Cdc42p activity during spontaneous cell polarizationErtugrul M Ozbudak
Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
Dev Cell 9:565-71. 2005....
Amplitude control of cell-cycle waves by nuclear importAttila Becskei
Department of Physics, Massachusetts Institute of Technology, 13-2008, Cambridge, MA 02139, USA
Nat Cell Biol 6:451-7. 2004..This classification of cellular processes outlines potential regulatory mechanisms that can contribute to faithful transmission of oscillations at different stages of the cell cycle...
Binary and graded responses in gene networksMatthieu Louis
EMBL-EBI, Structural Genomics Group, Cambridge CB10 1SD, UK
Sci STKE 2002:PE33. 2002..In view of that, it can be expected that forthcoming experimental studies on the combinatorial effects of signaling and transcriptional mechanisms will reveal new strategies for generating graded or binary responses...
