REBECCA BARON

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Maternal smoking and the retinoid pathway in the developing lung
    Sara E Manoli
    Department of Medicine, Division of Pulmonary and Critical Care, Brigham and Women s Hospital, Boston, MA, USA
    Respir Res 13:42. 2012
  2. pmc Chronic endotoxin exposure produces airflow obstruction and lung dendritic cell expansion
    Peggy S Lai
    Harvard School of Public Health, Boston, Massachusetts, USA
    Am J Respir Cell Mol Biol 47:209-17. 2012
  3. doi request reprint Genetically manipulated mouse models of lung disease: potential and pitfalls
    Rebecca M Baron
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Physiol Lung Cell Mol Physiol 302:L485-97. 2012
  4. ncbi request reprint Pathobiology of sepsis: are we still asking the same questions?
    Rebecca M Baron
    Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Am J Respir Cell Mol Biol 34:129-34. 2006
  5. pmc Distamycin A inhibits HMGA1-binding to the P-selectin promoter and attenuates lung and liver inflammation during murine endotoxemia
    Rebecca M Baron
    Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 5:e10656. 2010
  6. ncbi request reprint High-mobility group-I/Y proteins: potential role in the pathophysiology of critical illnesses
    Irvith M Carvajal
    Pulmonary and Critical Care Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Crit Care Med 30:S36-42. 2002
  7. pmc Heme oxygenase-1-derived carbon monoxide enhances the host defense response to microbial sepsis in mice
    Su Wol Chung
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Clin Invest 118:239-47. 2008

Research Grants

  1. HMG-1/Y Regulation of NOS2 Expression in Endotoxemia
    REBECCA BARON; Fiscal Year: 2007
  2. Role of NOS2 in Sepsis-Induced ARDS
    Rebecca M Baron; Fiscal Year: 2010

Collaborators

  • Miriam J Baron
  • Su Wol Chung
  • Peggy S Lai
  • Sara E Manoli
  • Irvith M Carvajal
  • Miguel A Pinilla
  • Manuela Cernadas
  • Joshua A Englert
  • Yolanda Porrata
  • David C Christiani
  • Jennifer M Fresco
  • Lacey A Smith
  • Ronald D Brown
  • James A Lederer
  • Chang Hyeok An
  • Alvaro A Macias
  • Wellington V Cardoso
  • Oliver Hofmann
  • Carrie A Vyhlidal
  • Winston Hide
  • Kathleen J Haley
  • Mark A Perrella

Detail Information

Publications7

  1. pmc Maternal smoking and the retinoid pathway in the developing lung
    Sara E Manoli
    Department of Medicine, Division of Pulmonary and Critical Care, Brigham and Women s Hospital, Boston, MA, USA
    Respir Res 13:42. 2012
    ..Thus, abnormalities in this pathway could mediate maternal smoking effects. We tested whether maternal smoking disrupts retinoic acid pathway expression and functioning in a murine model...
  2. pmc Chronic endotoxin exposure produces airflow obstruction and lung dendritic cell expansion
    Peggy S Lai
    Harvard School of Public Health, Boston, Massachusetts, USA
    Am J Respir Cell Mol Biol 47:209-17. 2012
    ..These findings point to a novel underlying mechanism of airflow obstruction as a result of occupational LPS exposure, and suggest molecular and cellular targets for therapeutic development...
  3. doi request reprint Genetically manipulated mouse models of lung disease: potential and pitfalls
    Rebecca M Baron
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Physiol Lung Cell Mol Physiol 302:L485-97. 2012
    ..We will attempt to review the current technological approaches of generating gene-targeted mice and the enormous dataset derived from these studies, providing a template for lung investigators...
  4. ncbi request reprint Pathobiology of sepsis: are we still asking the same questions?
    Rebecca M Baron
    Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Am J Respir Cell Mol Biol 34:129-34. 2006
  5. pmc Distamycin A inhibits HMGA1-binding to the P-selectin promoter and attenuates lung and liver inflammation during murine endotoxemia
    Rebecca M Baron
    Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 5:e10656. 2010
    ....
  6. ncbi request reprint High-mobility group-I/Y proteins: potential role in the pathophysiology of critical illnesses
    Irvith M Carvajal
    Pulmonary and Critical Care Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Crit Care Med 30:S36-42. 2002
    ....
  7. pmc Heme oxygenase-1-derived carbon monoxide enhances the host defense response to microbial sepsis in mice
    Su Wol Chung
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Clin Invest 118:239-47. 2008
    ..These data advocate HO-1-derived CO as an important mediator of the host defense response to sepsis and suggest CO administration as a possible treatment for the disease...

Research Grants3

  1. HMG-1/Y Regulation of NOS2 Expression in Endotoxemia
    REBECCA BARON; Fiscal Year: 2007
    ..These experiments will allow us to determine the role of HMG-I/Y in regulating NOS2 expression during endotoxemia and may reveal a novel target for improving outcomes from sepsis. ..
  2. Role of NOS2 in Sepsis-Induced ARDS
    Rebecca M Baron; Fiscal Year: 2010
    ..Achievement of the AIMS of this proposal hold significant promise for gaining novel insights into the pathobiology of sepsis-induced ARDS that can inform the development of new treatment strategies for these devastating syndromes. ..