GYORGY BAFFY

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Complexity and network dynamics in physiological adaptation: An integrated view
    GYORGY BAFFY
    Department of Medicine, VA Boston Healthcare System, Boston, MA, United States Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, United States Electronic address
    Physiol Behav 131:49-56. 2014
  2. doi request reprint Allostasis in nonalcoholic fatty liver disease: implications for risk assessment
    GYORGY BAFFY
    Department of Medicine, VA Boston Healthcare System and Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Dig Dis Sci 58:302-8. 2013
  3. doi request reprint Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace
    GYORGY BAFFY
    VA Boston Healthcare System and Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    J Hepatol 56:1384-91. 2012
  4. pmc Kupffer cells in non-alcoholic fatty liver disease: the emerging view
    GYORGY BAFFY
    Brigham and Women s Hospital and VA Boston Healthcare System, Harvard Medical School, Section of Gastroenterology, 150 S Huntington Ave, Boston, MA 02130, USA
    J Hepatol 51:212-23. 2009
  5. doi request reprint Uncoupling protein-2 and cancer
    GYORGY BAFFY
    VA Boston Healthcare System and Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Mitochondrion 10:243-52. 2010
  6. pmc Mitochondrial recoupling: a novel therapeutic strategy for cancer?
    G Baffy
    Department of Medicine, VA Boston Healthcare System and Brigham and Women s Hospital, Harvard Medical School, 150 S Huntington Avenue, Room A6 46, Boston, MA 02130, USA
    Br J Cancer 105:469-74. 2011
  7. ncbi request reprint Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2
    GYORGY BAFFY
    Division of Endocrinology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Hepatology 35:753-61. 2002
  8. doi request reprint Risk profile of hepatocellular carcinoma reveals dichotomy among US veterans
    Raffi Karagozian
    Section of Gastroenterology, Department of Medicine, VA Boston Healthcare System, Boston, MA 02130, USA
    J Gastrointest Cancer 44:318-24. 2013
  9. pmc Disordered purinergic signaling and abnormal cellular metabolism are associated with development of liver cancer in Cd39/ENTPD1 null mice
    Xiaofeng Sun
    Department of Medicine, Gastroenterology Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Hepatology 57:205-16. 2013

Research Grants

  1. UCP2 expression in colon cancer
    GYORGY BAFFY; Fiscal Year: 2002

Collaborators

  • Joseph Loscalzo
  • Anny Usheva
  • Elizabeth M Brunt
  • Xiaofeng Sun
  • Raffi Karagozian
  • Yan Wu
  • Moritz Schmelzle
  • Vikas P Sukhatme
  • Lihui Han
  • Daniel Leavitt
  • Errol Baker
  • Elliot B Tapper
  • Antoun Houranieh
  • Simon C Robson
  • Shu Bian
  • Linglin Li
  • Pankaj Seth
  • Wolfgang G Junger
  • Eva Csizmadia

Detail Information

Publications9

  1. ncbi request reprint Complexity and network dynamics in physiological adaptation: An integrated view
    GYORGY BAFFY
    Department of Medicine, VA Boston Healthcare System, Boston, MA, United States Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, United States Electronic address
    Physiol Behav 131:49-56. 2014
    ..Deconstruction of this complexity holds the promise of gaining novel insights into physiological adaptation in health and disease. ..
  2. doi request reprint Allostasis in nonalcoholic fatty liver disease: implications for risk assessment
    GYORGY BAFFY
    Department of Medicine, VA Boston Healthcare System and Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Dig Dis Sci 58:302-8. 2013
    ..The utility of this approach is illustrated for nonalcoholic fatty liver disease, a prevalent condition with common and less common outcomes...
  3. doi request reprint Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace
    GYORGY BAFFY
    VA Boston Healthcare System and Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    J Hepatol 56:1384-91. 2012
    ..This review summarizes current evidence as it pertains to the epidemiology, pathogenesis, and prevention of NAFLD-associated HCC...
  4. pmc Kupffer cells in non-alcoholic fatty liver disease: the emerging view
    GYORGY BAFFY
    Brigham and Women s Hospital and VA Boston Healthcare System, Harvard Medical School, Section of Gastroenterology, 150 S Huntington Ave, Boston, MA 02130, USA
    J Hepatol 51:212-23. 2009
    ..These events are further promoted by altered adipokine secretion and reactive oxygen species production. Specific targeting of these interactions may provide more effective strategies in the treatment of NAFLD...
  5. doi request reprint Uncoupling protein-2 and cancer
    GYORGY BAFFY
    VA Boston Healthcare System and Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Mitochondrion 10:243-52. 2010
    ..Elucidation of these interactions may identify novel anti-cancer strategies...
  6. pmc Mitochondrial recoupling: a novel therapeutic strategy for cancer?
    G Baffy
    Department of Medicine, VA Boston Healthcare System and Brigham and Women s Hospital, Harvard Medical School, 150 S Huntington Avenue, Room A6 46, Boston, MA 02130, USA
    Br J Cancer 105:469-74. 2011
    ..Here we review current evidence to suggest that inhibition of mitochondrial uncoupling may eliminate these responses and reveal novel anti-cancer strategies...
  7. ncbi request reprint Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2
    GYORGY BAFFY
    Division of Endocrinology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Hepatology 35:753-61. 2002
    ..We conclude that increased expression of UCP2 in the livers of mice with genetically or diet-induced obesity exerts neither protective nor deleterious effects on the severity of fatty liver disease...
  8. doi request reprint Risk profile of hepatocellular carcinoma reveals dichotomy among US veterans
    Raffi Karagozian
    Section of Gastroenterology, Department of Medicine, VA Boston Healthcare System, Boston, MA 02130, USA
    J Gastrointest Cancer 44:318-24. 2013
    ..In addition, recent evidence links HCC to diabetes...
  9. pmc Disordered purinergic signaling and abnormal cellular metabolism are associated with development of liver cancer in Cd39/ENTPD1 null mice
    Xiaofeng Sun
    Department of Medicine, Gastroenterology Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Hepatology 57:205-16. 2013
    ..Exogenous adenosine 5'-triphosphate (ATP) boosts these signaling pathways, whereas rapamycin inhibits such aberrant responses in hepatocytes...

Research Grants2

  1. UCP2 expression in colon cancer
    GYORGY BAFFY; Fiscal Year: 2002
    ..2) Assess the influence of UCP2 during colon carcinogenesis in UCP2-/- mice. 3) Investigate the potential role of UCP2 in human colorectal cancer ..