Swati Aggarwal

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi request reprint ALS drug development: reflections from the past and a way forward
    Swati Aggarwal
    Department of Neurology, Massachusetts General Hospital, Neurology Clinical Trials Unit, Charlestown, Massachusetts 02129, USA
    Neurotherapeutics 5:516-27. 2008
  2. pmc Safety and efficacy of lithium in combination with riluzole for treatment of amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial
    Swati P Aggarwal
    Neurology Clinical Trials Unit, Massachusetts General Hospital, Charlestown, MA, USA
    Lancet Neurol 9:481-8. 2010
  3. doi request reprint Toward more efficient clinical trials for amyotrophic lateral sclerosis
    Merit E Cudkowicz
    Massachusetts General Hospital, Boston, Massachusetts, USA
    Amyotroph Lateral Scler 11:259-65. 2010

Detail Information

Publications3

  1. doi request reprint ALS drug development: reflections from the past and a way forward
    Swati Aggarwal
    Department of Neurology, Massachusetts General Hospital, Neurology Clinical Trials Unit, Charlestown, Massachusetts 02129, USA
    Neurotherapeutics 5:516-27. 2008
    ..We present a critical overview of past clinical trials, how therapies are selected for testing in people, challenges with ALS clinical trial design and conduct, and ways to best move forward...
  2. pmc Safety and efficacy of lithium in combination with riluzole for treatment of amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial
    Swati P Aggarwal
    Neurology Clinical Trials Unit, Massachusetts General Hospital, Charlestown, MA, USA
    Lancet Neurol 9:481-8. 2010
    ..In a pilot study, lithium treatment slowed progression of amyotrophic lateral sclerosis (ALS). We aimed to confirm or disprove these findings by assessing the safety and efficacy of lithium in combination with riluzole in patients with ALS...
  3. doi request reprint Toward more efficient clinical trials for amyotrophic lateral sclerosis
    Merit E Cudkowicz
    Massachusetts General Hospital, Boston, Massachusetts, USA
    Amyotroph Lateral Scler 11:259-65. 2010
    ..Here we summarize our current thinking about phase II design options and the potential benefits of a clinical trial network for phase II trials in ALS...