Research Topics
Genomes and GenesSpecies | Ingrid GlurichSummaryAffiliation: Marshfield Clinic Country: USA Publications
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Detail Information
Publications
Lack of evidence of WNT3A as a candidate gene for congenital vertebral malformationsNader Ghebranious
University of Wisconsin Medical School, Madison, Wisconsin, USA and Geriatrics Research, Education, and Clinical Center, William S, Middleton Veterans Administration Medical Center, Madison, Wisconsin, USA
Scoliosis 2:13. 2007..We hypothesized that WNT3A mutations might account for a subset of congenital vertebral malformations...
Understanding the pharmacogenetic approach to warfarin dosingIngrid Glurich
Office of Scientific Writing and Publications, Marshfield Clinic Research Foundation, Marshfield, WI, USA
Heart Fail Rev 15:239-48. 2010..Finally, unresolved issues in improving clinical care of warfarin patients and future directions are provided...
Absence of novel CYP4F2 and VKORC1 coding region DNA variants in patients requiring high warfarin dosesJames K Burmester
Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA
Clin Med Res 9:119-24. 2011....
A prospective, randomized pilot trial of model-based warfarin dose initiation using CYP2C9 genotype and clinical dataMichael A Hillman
Center for Human Genetics, Marshfield Clinic Research Foundation, 1000 North Oak Avenue, Marshfield, WI 54449, USA
Clin Med Res 3:137-45. 2005..The feasibility of prospective CYP2C9 model-based warfarin dosing has not yet been assessed...
A missense T (Brachyury) mutation contributes to vertebral malformationsNader Ghebranious
Molecular Diagnostic Research Laboratory, Marshfield Clinic, Marshfield, Wisconsin 54449, USA
J Bone Miner Res 23:1576-83. 2008..TBX6 mutations do not seem to be associated with CVM. We hypothesize that epistatic interactions between T and other developmental genes and the environment modulate the phenotypic consequences of T variants...
Evaluation of genetic factors for warfarin dose predictionMichael D Caldwell
Center for Human Genetics, Marshfield Clinic Research Foundation, 1000 North Oak Avenue, Marshfield, WI 54449, USA
Clin Med Res 5:8-16. 2007..To ultimately improve dosing of warfarin, we evaluated models for stable maintenance dose that incorporated both clinical and genetic factors...
DLL3 as a candidate gene for vertebral malformationsPhilip F Giampietro
Department of Medical Genetic Services, Marshfield Clinic, Marshfield, Wisconsin 54449, USA
Am J Med Genet A 140:2447-53. 2006....
Relative impact of covariates in prescribing warfarin according to CYP2C9 genotypeMichael A Hillman
Department of Care Management, Marshfield Clinic, Marshfield, Wisconsin, USA
Pharmacogenetics 14:539-47. 2004..7% of all dosing variability according to multiple regression. These results will help strengthen the mathematical models that are currently being developed for prospective gene-based warfarin dosing...
CYP4F2 genetic variant alters required warfarin doseMichael D Caldwell
Department of Surgery, Marshfield Clinic, Marshfield, WI, USA
Blood 111:4106-12. 2008..Genetic variation of CYP4F2 was associated with a clinically relevant effect on warfarin requirement...
Progress in the understanding of the genetic etiology of vertebral segmentation disorders in humansPhilip F Giampietro
Department of Medical Genetic Services, Marshfield Clinic, 1000 North Oak Avenue, Marshfield, WI 54449, USA
Ann N Y Acad Sci 1151:38-67. 2009....
Applying case definition criteria to irritable bowel syndromeSteven H Yale
Department of Internal Medicine, Marshfield Clinic, 1000 North Oak Avenue, Marshfield, Wisconsin 54449, USA
Clin Med Res 6:9-16. 2008..We sought to identify and validate cases of IBS based on the Manning, Rome I and Rome II diagnostic criteria in a rural practice setting...
A pilot study of gene/gene and gene/environment interactions in Alzheimer diseaseNader Ghebranious
Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA
Clin Med Res 9:17-25. 2011..The purpose of this pilot study was to explore gene/gene and gene/environment associations in AD and to obtain data for sample size estimates for larger, more definitive studies of AD...
Evaluation of SLC35A3 as a candidate gene for human vertebral malformationsNader Ghebranious
Molecular Diagnostics Genotyping Laboratory, Marshfield Clinic, Marshfield, Wisconsin, USA
Am J Med Genet A 140:1346-8. 2006
Analysis of the inhibitory potential of Ginkgo biloba, Echinacea purpurea, and Serenoa repens on the metabolic activity of cytochrome P450 3A4, 2D6, and 2C9Steven H Yale
Department of Internal Medicine, Marshfield Clinic, Marshfield, WI 54449, USA
J Altern Complement Med 11:433-9. 2005....
Tamoxifen-induced venothromboembolic events: exploring validation of putative genetic associationIngrid Glurich
Office of Scientific Writing and Publication, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA
Clin Med Res 11:16-25. 2013..A pilot study to examine accrual rates, efficiency of data capture approaches, study design and genotyping capacity for a future genetic validation study was undertaken...
Predicting atrial fibrillation and flutter using Electronic Health RecordsShreyas Karnik
Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield Clinic, 1000 North Oak Avenue, Marshfield, WI 54449, USA
Conf Proc IEEE Eng Med Biol Soc 2012:5562-5. 2012..The combination of textual and coded data achieved comparable performance. The study results attest to the relative merit of utilizing textual data to complement the use of coded data for disease onset prediction modeling...
Serologic testing in connective tissue diseasesDana E Habash-Bseiso
Department of Internal Medicine, Marshfield Clinic, Marshfield, WI 54449, USA
Clin Med Res 3:190-3. 2005
