Zeng W, McFarland M, Zhou B, Holtfreter S, Flesher S, Cheung A, et al. Staphylococcal enterotoxin A-activated regulatory T cells promote allergen-specific TH2 response to intratracheal allergen inoculation. J Allergy Clin Immunol. 2017;139:508-518.e4 pubmed publisher
..Depletion of Treg cells abolished these effects of SEA and IL-13 expression in OVA-specific T cells. SEA promoted TH2 responses of allergen-specific T cells and asthma pathogenesis by activating Treg cells. ..
Zeng W, Sollars V, Belalcazar A. Domain requirements for the diverse immune regulatory functions of foxp3. Mol Immunol. 2011;48:1932-9 pubmed publisher
..In any case, deletion of a particular domain showed similar effects on all 3 functions of Foxp3. Therefore defining each of the immunological features of Treg cells requires intact Foxp3 proteins. ..