Zijian Xie


Affiliation: Marshall University
Country: USA


  1. Banerjee M, Cui X, Li Z, Yu H, Cai L, Jia X, et al. Na/K-ATPase Y260 Phosphorylation-mediated Src Regulation in Control of Aerobic Glycolysis and Tumor Growth. Sci Rep. 2018;8:12322 pubmed publisher
    ..These findings suggest that ?1 Na/K-ATPase works as a tumor suppressor and that a loss of Na/K-ATPase-mediated Src regulation may lead to Warburg phenotype in cancer. ..
  2. Feng X, Wang C, Xu Y, Turley J, Xie Z, Pierre S, et al. Topical Digitoxigenin for Wound Healing: A Feasibility Study. Bioengineering (Basel). 2018;5: pubmed publisher
    ..However, the wound healing effect of digitoxigenin and its mechanisms need to be further investigated in future studies. ..
  3. Xie J, Ye Q, Cui X, Madan N, Yi Q, Pierre S, et al. Expression of rat Na-K-ATPase α2 enables ion pumping but not ouabain-induced signaling in α1-deficient porcine renal epithelial cells. Am J Physiol Cell Physiol. 2015;309:C373-82 pubmed publisher
    ..This further implies that the signaling mechanism of Na-K-ATPase is isoform specific, thereby supporting a model where α1 and α2 isoforms play distinct roles in mediating contraction and signaling in myocytes. ..
  4. Madan N, Xu Y, Duan Q, Banerjee M, Larre I, Pierre S, et al. Src-independent ERK signaling through the rat α3 isoform of Na/K-ATPase. Am J Physiol Cell Physiol. 2017;312:C222-C232 pubmed publisher
    ..Hence, α3 expression confers signaling and pumping properties that are clearly distinct from that of cells expressing Na/K-ATPase α1. ..
  5. Cui X, Xie Z. Protein Interaction and Na/K-ATPase-Mediated Signal Transduction. Molecules. 2017;22: pubmed publisher
    ..This article will focus on the role of protein interaction in NKA-mediated signal transduction, and its potential utility as target for developing new therapeutics. ..
  6. Yu H, Cui X, Zhang J, Xie J, Banerjee M, Pierre S, et al. Heterogeneity of Signal Transduction by Na/K-ATPase ?-Isoforms: Role of Src Interaction. Am J Physiol Cell Physiol. 2017;:ajpcell.00124.2017 pubmed publisher
    ..The sequences surrounding the putative Src-binding sites in ?2 are highly conserved across species, suggesting that the lack of Src-binding may play a physiologically important and isoform-specific role...