Research Topics
| Rosemary StuartSummaryAffiliation: Marquette University Country: USA Publications
Research Grants
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Detail Information
Publications
Mapping of the Saccharomyces cerevisiae Oxa1-mitochondrial ribosome interface and identification of MrpL40, a ribosomal protein in close proximity to Oxa1 and critical for oxidative phosphorylation complex assemblyLixia Jia
Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53233, USA
Eukaryot Cell 8:1792-802. 2009....- Rcf1 and Rcf2, members of the hypoxia-induced gene 1 protein family, are critical components of the mitochondrial cytochrome bc1-cytochrome c oxidase supercomplexVera Strogolova
Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin, USA
Mol Cell Biol 32:1363-73. 2012..Based on our findings, we propose a model where the Hig1 proteins regulate the COX enzyme activity through Cox3 and associated Cox12 protein, in a manner that may be influenced by the neighboring AAC proteins... 
Supercomplex organization of the oxidative phosphorylation enzymes in yeast mitochondriaRosemary A Stuart
Dept of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA
J Bioenerg Biomembr 40:411-7. 2008..In addition, the existence of dimeric/oligomeric F(1)F(o)-ATP synthase complexes and their proposed role in establishment of the cristae architecture of the inner mitochondrial membrane shall also be discussed...- Mitochondrial biogenesis: is an old dog still teaching us new tricks? Meeting on the Assembly of the Mitochondrial Respiratory ChainRosemary A Stuart
Department of Biological Sciences, Marquette University, 530 N 15th Street, Milwaukee, WI 53233, USA
EMBO Rep 9:33-8. 2008 
Insertion of proteins into the inner membrane of mitochondria: the role of the Oxa1 complexRosemary Stuart
Department of Biology, Marquette University, 530 N 15th Street, Milwaukee, WI 53233, USA
Biochim Biophys Acta 1592:79-87. 2002..The evidence to demonstrate that the Oxa1/YidC/Alb3 protein family represents a novel evolutionarily conserved membrane insertion machinery is reviewed here...- The F1F0-ATP synthase complex influences the assembly state of the cytochrome bc1-cytochrome oxidase supercomplex and its association with the TIM23 machinerySonika Saddar
Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53233, USA
J Biol Chem 283:6677-86. 2008..e. the ATP synthase, may influence that of another supercomplex, namely the cytochrome bc1-COX complex... - Oxa1 directly interacts with Atp9 and mediates its assembly into the mitochondrial F1Fo-ATP synthase complexLixia Jia
Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA
Mol Biol Cell 18:1897-908. 2007..We propose that by directly interacting with newly synthesized Atp9 in a posttranslational manner, Oxa1 is required to maintain the assembly competence of the Atp9-F(1)-subcomplex for its association with Atp6... - The yeast Aac2 protein exists in physical association with the cytochrome bc1-COX supercomplex and the TIM23 machineryMary K Dienhart
Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA
Mol Biol Cell 19:3934-43. 2008..The physiological implications of the association of AAC with the cytochrome bc(1)-COX-TIM23 supercomplex are also discussed... - Yeast Oxa1 interacts with mitochondrial ribosomes: the importance of the C-terminal region of Oxa1Lixia Jia
Department of Biological Sciences, Marquette University, 530 N 15th Street, Milwaukee, WI 53233, USA
EMBO J 22:6438-47. 2003..Mrp20 is homologous to L23, a subunit located next to the peptide exit tunnel of the ribosome. We propose that the interaction of Oxa1 with the ribosome serves to enhance a coupling of translation and membrane insertion events... - Functional analysis of subunit e of the F1Fo-ATP synthase of the yeast Saccharomyces cerevisiae: importance of the N-terminal membrane anchor regionValerie Everard-Gigot
Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA
Eukaryot Cell 4:346-55. 2005..Finally, we propose a model to explain how Su e supports the assembly of the ATP synthase dimers-oligomers in the mitochondrial membrane... - Characterization of Mmp37p, a Saccharomyces cerevisiae mitochondrial matrix protein with a role in mitochondrial protein importMichelle R Gallas
Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Mol Biol Cell 17:4051-62. 2006.... - In vitro analysis of yeast mitochondrial protein importRosemary A Stuart
Marquette University, Milwaukee, Wisconsin, USA
Curr Protoc Cell Biol . 2007..It can also be used to study the import mechanism and to investigate mitochondrial matrix translation of proteins and their export... - Formation of the yeast F1F0-ATP synthase dimeric complex does not require the ATPase inhibitor protein, Inh1Mary Dienhart
Department of Biology, Marquette University, Milwaukee, Wisconsin 53233, USA
J Biol Chem 277:39289-95. 2002.... - The yeast F(1)F(0)-ATP synthase: analysis of the molecular organization of subunit g and the importance of a conserved GXXXG motifSonika Saddar
Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53233, USA
J Biol Chem 280:24435-42. 2005..We suggest that the GXXXG motif may not be the sole basis for a Su g-Su e interaction, and possibly these dimerization motifs may enable both Su g and Su e to interact with another mitochondrial protein... - Structural characterization of the transmembrane domain from subunit e of yeast F1Fo-ATP synthase: a helical GXXXG motif located just under the micelle surfaceHuili Yao
Chemical Proteomics Facility at Marquette, Department of Chemistry, Marquette University, P O Box 1881, Milwaukee, Wisconsin 53201 1881, USA
Biochemistry 47:1910-7. 2008.... - Su e of the yeast F1Fo-ATP synthase forms homodimersSusanne Brunner
Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53233, USA
J Biol Chem 277:48484-9. 2002..Finally, we propose a model for the molecular basis of the homodimerization of the Su e proteins... - Chapter 11 Supercomplex organization of the yeast respiratory chain complexes and the ADP/ATP carrier proteinsRosemary A Stuart
Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin, USA
Methods Enzymol 456:191-208. 2009..The method used to analyze the cytochrome bc(1)-COX-AAC supercomplex and to affinity purify the Aac2 isoform and its associating proteins from S. cerevisiae mitochondria will be outlined in this chapter... - Cardiolipin stabilizes respiratory chain supercomplexesKathy Pfeiffer
Zentrum der Biologischen Chemie, , D-60590 Frankfurt, Germany
J Biol Chem 278:52873-80. 2003..We show that a cardiolipin-deficient strain harbored almost inactive resting cytochrome c oxidase in the membrane. Transition to the fully active pulsed state occurred on a minute time scale...
Research Grants
- Molecular analysis of the dimeric F1/F0-ATP synthaseRosemary Stuart; Fiscal Year: 2006....