Rosemary Stuart

Summary

Affiliation: Marquette University
Country: USA

Publications

  1. pmc Mapping of the Saccharomyces cerevisiae Oxa1-mitochondrial ribosome interface and identification of MrpL40, a ribosomal protein in close proximity to Oxa1 and critical for oxidative phosphorylation complex assembly
    Lixia Jia
    Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53233, USA
    Eukaryot Cell 8:1792-802. 2009
  2. pmc Rcf1 and Rcf2, members of the hypoxia-induced gene 1 protein family, are critical components of the mitochondrial cytochrome bc1-cytochrome c oxidase supercomplex
    Vera Strogolova
    Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin, USA
    Mol Cell Biol 32:1363-73. 2012
  3. doi request reprint Supercomplex organization of the oxidative phosphorylation enzymes in yeast mitochondria
    Rosemary A Stuart
    Dept of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA
    J Bioenerg Biomembr 40:411-7. 2008
  4. pmc Mitochondrial biogenesis: is an old dog still teaching us new tricks? Meeting on the Assembly of the Mitochondrial Respiratory Chain
    Rosemary A Stuart
    Department of Biological Sciences, Marquette University, 530 N 15th Street, Milwaukee, WI 53233, USA
    EMBO Rep 9:33-8. 2008
  5. ncbi request reprint Insertion of proteins into the inner membrane of mitochondria: the role of the Oxa1 complex
    Rosemary Stuart
    Department of Biology, Marquette University, 530 N 15th Street, Milwaukee, WI 53233, USA
    Biochim Biophys Acta 1592:79-87. 2002
  6. doi request reprint The F1F0-ATP synthase complex influences the assembly state of the cytochrome bc1-cytochrome oxidase supercomplex and its association with the TIM23 machinery
    Sonika Saddar
    Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53233, USA
    J Biol Chem 283:6677-86. 2008
  7. pmc Oxa1 directly interacts with Atp9 and mediates its assembly into the mitochondrial F1Fo-ATP synthase complex
    Lixia Jia
    Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA
    Mol Biol Cell 18:1897-908. 2007
  8. pmc The yeast Aac2 protein exists in physical association with the cytochrome bc1-COX supercomplex and the TIM23 machinery
    Mary K Dienhart
    Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA
    Mol Biol Cell 19:3934-43. 2008
  9. pmc Yeast Oxa1 interacts with mitochondrial ribosomes: the importance of the C-terminal region of Oxa1
    Lixia Jia
    Department of Biological Sciences, Marquette University, 530 N 15th Street, Milwaukee, WI 53233, USA
    EMBO J 22:6438-47. 2003
  10. pmc Functional analysis of subunit e of the F1Fo-ATP synthase of the yeast Saccharomyces cerevisiae: importance of the N-terminal membrane anchor region
    Valerie Everard-Gigot
    Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA
    Eukaryot Cell 4:346-55. 2005

Research Grants

Collaborators

Detail Information

Publications18

  1. pmc Mapping of the Saccharomyces cerevisiae Oxa1-mitochondrial ribosome interface and identification of MrpL40, a ribosomal protein in close proximity to Oxa1 and critical for oxidative phosphorylation complex assembly
    Lixia Jia
    Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53233, USA
    Eukaryot Cell 8:1792-802. 2009
    ....
  2. pmc Rcf1 and Rcf2, members of the hypoxia-induced gene 1 protein family, are critical components of the mitochondrial cytochrome bc1-cytochrome c oxidase supercomplex
    Vera Strogolova
    Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin, USA
    Mol Cell Biol 32:1363-73. 2012
    ..Based on our findings, we propose a model where the Hig1 proteins regulate the COX enzyme activity through Cox3 and associated Cox12 protein, in a manner that may be influenced by the neighboring AAC proteins...
  3. doi request reprint Supercomplex organization of the oxidative phosphorylation enzymes in yeast mitochondria
    Rosemary A Stuart
    Dept of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA
    J Bioenerg Biomembr 40:411-7. 2008
    ..In addition, the existence of dimeric/oligomeric F(1)F(o)-ATP synthase complexes and their proposed role in establishment of the cristae architecture of the inner mitochondrial membrane shall also be discussed...
  4. pmc Mitochondrial biogenesis: is an old dog still teaching us new tricks? Meeting on the Assembly of the Mitochondrial Respiratory Chain
    Rosemary A Stuart
    Department of Biological Sciences, Marquette University, 530 N 15th Street, Milwaukee, WI 53233, USA
    EMBO Rep 9:33-8. 2008
  5. ncbi request reprint Insertion of proteins into the inner membrane of mitochondria: the role of the Oxa1 complex
    Rosemary Stuart
    Department of Biology, Marquette University, 530 N 15th Street, Milwaukee, WI 53233, USA
    Biochim Biophys Acta 1592:79-87. 2002
    ..The evidence to demonstrate that the Oxa1/YidC/Alb3 protein family represents a novel evolutionarily conserved membrane insertion machinery is reviewed here...
  6. doi request reprint The F1F0-ATP synthase complex influences the assembly state of the cytochrome bc1-cytochrome oxidase supercomplex and its association with the TIM23 machinery
    Sonika Saddar
    Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53233, USA
    J Biol Chem 283:6677-86. 2008
    ..e. the ATP synthase, may influence that of another supercomplex, namely the cytochrome bc1-COX complex...
  7. pmc Oxa1 directly interacts with Atp9 and mediates its assembly into the mitochondrial F1Fo-ATP synthase complex
    Lixia Jia
    Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA
    Mol Biol Cell 18:1897-908. 2007
    ..We propose that by directly interacting with newly synthesized Atp9 in a posttranslational manner, Oxa1 is required to maintain the assembly competence of the Atp9-F(1)-subcomplex for its association with Atp6...
  8. pmc The yeast Aac2 protein exists in physical association with the cytochrome bc1-COX supercomplex and the TIM23 machinery
    Mary K Dienhart
    Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA
    Mol Biol Cell 19:3934-43. 2008
    ..The physiological implications of the association of AAC with the cytochrome bc(1)-COX-TIM23 supercomplex are also discussed...
  9. pmc Yeast Oxa1 interacts with mitochondrial ribosomes: the importance of the C-terminal region of Oxa1
    Lixia Jia
    Department of Biological Sciences, Marquette University, 530 N 15th Street, Milwaukee, WI 53233, USA
    EMBO J 22:6438-47. 2003
    ..Mrp20 is homologous to L23, a subunit located next to the peptide exit tunnel of the ribosome. We propose that the interaction of Oxa1 with the ribosome serves to enhance a coupling of translation and membrane insertion events...
  10. pmc Functional analysis of subunit e of the F1Fo-ATP synthase of the yeast Saccharomyces cerevisiae: importance of the N-terminal membrane anchor region
    Valerie Everard-Gigot
    Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA
    Eukaryot Cell 4:346-55. 2005
    ..Finally, we propose a model to explain how Su e supports the assembly of the ATP synthase dimers-oligomers in the mitochondrial membrane...
  11. pmc Characterization of Mmp37p, a Saccharomyces cerevisiae mitochondrial matrix protein with a role in mitochondrial protein import
    Michelle R Gallas
    Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Mol Biol Cell 17:4051-62. 2006
    ....
  12. ncbi request reprint In vitro analysis of yeast mitochondrial protein import
    Rosemary A Stuart
    Marquette University, Milwaukee, Wisconsin, USA
    Curr Protoc Cell Biol . 2007
    ..It can also be used to study the import mechanism and to investigate mitochondrial matrix translation of proteins and their export...
  13. ncbi request reprint Formation of the yeast F1F0-ATP synthase dimeric complex does not require the ATPase inhibitor protein, Inh1
    Mary Dienhart
    Department of Biology, Marquette University, Milwaukee, Wisconsin 53233, USA
    J Biol Chem 277:39289-95. 2002
    ....
  14. ncbi request reprint The yeast F(1)F(0)-ATP synthase: analysis of the molecular organization of subunit g and the importance of a conserved GXXXG motif
    Sonika Saddar
    Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53233, USA
    J Biol Chem 280:24435-42. 2005
    ..We suggest that the GXXXG motif may not be the sole basis for a Su g-Su e interaction, and possibly these dimerization motifs may enable both Su g and Su e to interact with another mitochondrial protein...
  15. doi request reprint Structural characterization of the transmembrane domain from subunit e of yeast F1Fo-ATP synthase: a helical GXXXG motif located just under the micelle surface
    Huili Yao
    Chemical Proteomics Facility at Marquette, Department of Chemistry, Marquette University, P O Box 1881, Milwaukee, Wisconsin 53201 1881, USA
    Biochemistry 47:1910-7. 2008
    ....
  16. ncbi request reprint Su e of the yeast F1Fo-ATP synthase forms homodimers
    Susanne Brunner
    Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53233, USA
    J Biol Chem 277:48484-9. 2002
    ..Finally, we propose a model for the molecular basis of the homodimerization of the Su e proteins...
  17. doi request reprint Chapter 11 Supercomplex organization of the yeast respiratory chain complexes and the ADP/ATP carrier proteins
    Rosemary A Stuart
    Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin, USA
    Methods Enzymol 456:191-208. 2009
    ..The method used to analyze the cytochrome bc(1)-COX-AAC supercomplex and to affinity purify the Aac2 isoform and its associating proteins from S. cerevisiae mitochondria will be outlined in this chapter...
  18. ncbi request reprint Cardiolipin stabilizes respiratory chain supercomplexes
    Kathy Pfeiffer
    Zentrum der Biologischen Chemie, Universitatsklinikum Frankfurt, D 60590 Frankfurt, Germany
    J Biol Chem 278:52873-80. 2003
    ..We show that a cardiolipin-deficient strain harbored almost inactive resting cytochrome c oxidase in the membrane. Transition to the fully active pulsed state occurred on a minute time scale...

Research Grants5

  1. Molecular analysis of the dimeric F1/F0-ATP synthase
    Rosemary Stuart; Fiscal Year: 2006
    ....