John R Mantsch

Summary

Affiliation: Marquette University
Country: USA

Publications

  1. ncbi Levo-tetrahydropalmatine attenuates cocaine self-administration under a progressive-ratio schedule and cocaine discrimination in rats
    John R Mantsch
    Department of Biomedical Sciences, Marquette University, Milwaukee, WI 53201 1881, USA
    Pharmacol Biochem Behav 97:310-6. 2010
  2. ncbi Involvement of noradrenergic neurotransmission in the stress- but not cocaine-induced reinstatement of extinguished cocaine-induced conditioned place preference in mice: role for β-2 adrenergic receptors
    John R Mantsch
    Department of Biomedical Sciences, Marquette University, Milwaukee, WI 53201, USA
    Neuropsychopharmacology 35:2165-78. 2010
  3. ncbi Neuroadaptations in the cellular and postsynaptic group 1 metabotropic glutamate receptor mGluR5 and Homer proteins following extinction of cocaine self-administration
    M Behnam Ghasemzadeh
    Department of Biomedical Sciences, Integrative Neuroscience Research Center, Marquette University, Milwaukee, WI 53201, United States
    Neurosci Lett 452:167-71. 2009
  4. ncbi Stressor- and corticotropin releasing factor-induced reinstatement and active stress-related behavioral responses are augmented following long-access cocaine self-administration by rats
    John R Mantsch
    Department of Biomedical Sciences, Marquette University, Schroeder Health Complex, P O Box 1881, Milwaukee, WI 53201 1881, USA
    Psychopharmacology (Berl) 195:591-603. 2008
  5. ncbi Daily cocaine self-administration under long-access conditions augments restraint-induced increases in plasma corticosterone and impairs glucocorticoid receptor-mediated negative feedback in rats
    John R Mantsch
    Department of Biomedical Sciences, Box 1881, Marquette University, Milwaukee, WI 53201 1881, USA
    Brain Res 1167:101-11. 2007
  6. ncbi Surgical adrenalectomy with diurnal corticosterone replacement slows escalation and prevents the augmentation of cocaine-induced reinstatement in rats self-administering cocaine under long-access conditions
    John R Mantsch
    Department of Biomedical Sciences, Marquette University, Milwaukee, WI 53201, USA
    Neuropsychopharmacology 33:814-26. 2008
  7. ncbi Levo-tetrahydropalmatine attenuates cocaine self-administration and cocaine-induced reinstatement in rats
    John R Mantsch
    Department of Biomedical Sciences, Marquette University, Schroeder Health Complex, P O Box 1881, Milwaukee, WI 53201 1881, USA
    Psychopharmacology (Berl) 192:581-91. 2007
  8. ncbi Elevation of glucocorticoids is necessary but not sufficient for the escalation of cocaine self-administration by chronic electric footshock stress in rats
    John R Mantsch
    Department of Biomedical Sciences, Marquette University, Milwaukee, WI 53201 1881, USA
    Neuropsychopharmacology 32:367-76. 2007
  9. ncbi Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats
    John R Mantsch
    The Laboratory of the Biology of Addictive Diseases, The Rockefeller University, New York, NY, USA
    Psychopharmacology (Berl) 175:26-36. 2004
  10. ncbi N-acetyl cysteine-induced blockade of cocaine-induced reinstatement
    David A Baker
    Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Ann N Y Acad Sci 1003:349-51. 2003

Research Grants

  1. Cystine-Glu Antiporter & PCP Model of Schizophrenia
    David Baker; Fiscal Year: 2005
  2. Targeting System Xc- for the Treatment of Addiction
    David Baker; Fiscal Year: 2009
  3. Cystine-Glutamate Antiporters and Cocaine Reinstatement
    David Baker; Fiscal Year: 2007
  4. Cystine-Glutamate Antiporters and Cocaine Reinstatement
    David Baker; Fiscal Year: 2007
  5. Targeting System Xc- for the Treatment of Addiction
    John R Mantsch; Fiscal Year: 2010

Detail Information

Publications19

  1. ncbi Levo-tetrahydropalmatine attenuates cocaine self-administration under a progressive-ratio schedule and cocaine discrimination in rats
    John R Mantsch
    Department of Biomedical Sciences, Marquette University, Milwaukee, WI 53201 1881, USA
    Pharmacol Biochem Behav 97:310-6. 2010
    ....
  2. ncbi Involvement of noradrenergic neurotransmission in the stress- but not cocaine-induced reinstatement of extinguished cocaine-induced conditioned place preference in mice: role for β-2 adrenergic receptors
    John R Mantsch
    Department of Biomedical Sciences, Marquette University, Milwaukee, WI 53201, USA
    Neuropsychopharmacology 35:2165-78. 2010
    ....
  3. ncbi Neuroadaptations in the cellular and postsynaptic group 1 metabotropic glutamate receptor mGluR5 and Homer proteins following extinction of cocaine self-administration
    M Behnam Ghasemzadeh
    Department of Biomedical Sciences, Integrative Neuroscience Research Center, Marquette University, Milwaukee, WI 53201, United States
    Neurosci Lett 452:167-71. 2009
    ..Concurrent plasticity in the scaffolding proteins further suggests that mGluR5 receptor neuroadaptations may have implications for synaptic function...
  4. ncbi Stressor- and corticotropin releasing factor-induced reinstatement and active stress-related behavioral responses are augmented following long-access cocaine self-administration by rats
    John R Mantsch
    Department of Biomedical Sciences, Marquette University, Schroeder Health Complex, P O Box 1881, Milwaukee, WI 53201 1881, USA
    Psychopharmacology (Berl) 195:591-603. 2008
    ..Excessive cocaine use may increase susceptibility to stressor-induced relapse through alterations in brain corticotropin-releasing factor (CRF) responsiveness...
  5. ncbi Daily cocaine self-administration under long-access conditions augments restraint-induced increases in plasma corticosterone and impairs glucocorticoid receptor-mediated negative feedback in rats
    John R Mantsch
    Department of Biomedical Sciences, Box 1881, Marquette University, Milwaukee, WI 53201 1881, USA
    Brain Res 1167:101-11. 2007
    ..The findings suggest that cocaine use produces persistent changes in individual responsiveness to stressors that may contribute to the addiction process...
  6. ncbi Surgical adrenalectomy with diurnal corticosterone replacement slows escalation and prevents the augmentation of cocaine-induced reinstatement in rats self-administering cocaine under long-access conditions
    John R Mantsch
    Department of Biomedical Sciences, Marquette University, Milwaukee, WI 53201, USA
    Neuropsychopharmacology 33:814-26. 2008
    ....
  7. ncbi Levo-tetrahydropalmatine attenuates cocaine self-administration and cocaine-induced reinstatement in rats
    John R Mantsch
    Department of Biomedical Sciences, Marquette University, Schroeder Health Complex, P O Box 1881, Milwaukee, WI 53201 1881, USA
    Psychopharmacology (Berl) 192:581-91. 2007
    ..Accordingly, l-THP has been reported to reduce heroin craving and relapse in recovering addicts...
  8. ncbi Elevation of glucocorticoids is necessary but not sufficient for the escalation of cocaine self-administration by chronic electric footshock stress in rats
    John R Mantsch
    Department of Biomedical Sciences, Marquette University, Milwaukee, WI 53201 1881, USA
    Neuropsychopharmacology 32:367-76. 2007
    ....
  9. ncbi Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats
    John R Mantsch
    The Laboratory of the Biology of Addictive Diseases, The Rockefeller University, New York, NY, USA
    Psychopharmacology (Berl) 175:26-36. 2004
    ..The investigation of rodent cocaine self-administration (SA) under conditions that promote escalating patterns of intake may provide insight into the loss of control over drug use that is central to human addiction...
  10. ncbi N-acetyl cysteine-induced blockade of cocaine-induced reinstatement
    David A Baker
    Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Ann N Y Acad Sci 1003:349-51. 2003
  11. ncbi Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse
    David A Baker
    Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Nat Neurosci 6:743-9. 2003
    ..Thus, withdrawal from repeated cocaine increases susceptibility to relapse in part by reducing cystine/glutamate exchange, and restoring exchanger activity prevents cocaine-primed drug seeking...
  12. ncbi Contribution of cystine-glutamate antiporters to the psychotomimetic effects of phencyclidine
    David A Baker
    Department of Biomedical Sciences, Marquette University, Milwaukee, WI 53233, USA
    Neuropsychopharmacology 33:1760-72. 2008
    ..These data advance cystine-glutamate antiporters as novel targets capable of reversing the psychotomimetic effects of PCP...
  13. ncbi Repeated N-acetylcysteine administration alters plasticity-dependent effects of cocaine
    Aric Madayag
    Department of Biomedical Sciences, Marquette University, Milwaukee, Wisconsin 53233, USA
    J Neurosci 27:13968-76. 2007
    ....
  14. ncbi Valacyclovir in the treatment of genital herpes and herpes zoster
    David A Baker
    Division of Infectious Diseases, Department of Obstetrics/Gynaecology, State University of New York at Stony Brook, Stony Brook, New York 11794-8091, USA
    Expert Opin Pharmacother 3:51-8. 2002
    ....
  15. ncbi Issues and management of herpes in pregnancy
    David A Baker
    Division of Infectious Diseases, Health Sciences Center, State University of New York at Stony Brook, 11794-8091, USA
    Int J Fertil Womens Med 47:129-35. 2002
    ....
  16. ncbi The origin and neuronal function of in vivo nonsynaptic glutamate
    David A Baker
    Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Neurosci 22:9134-41. 2002
    ..These results suggest that nonvesicular release from the cystine-glutamate antiporter is the primary source of in vivo extracellular glutamate and that this glutamate can modulate both glutamate and dopamine transmission...
  17. ncbi Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine
    Zheng-Xiong Xi
    Department of Physiology and Neuroscience, Medical University of South Carolina, 173 Ashley Avenue, BSB 403, Charleston, SC 29464, USA
    J Pharmacol Exp Ther 303:608-15. 2002
    ..Together, these data demonstrate that repeated cocaine produces an enduring reduction in mGluR2/3 function in the nucleus accumbens...
  18. ncbi Inhibition of non-vesicular glutamate release by group III metabotropic glutamate receptors in the nucleus accumbens
    Zheng Xiong Xi
    Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston, SC, USA
    J Neurochem 87:1204-12. 2003
    ..Together, these data indicate that group III mGluRs regulate in vivo extracellular glutamate in the nucleus accumbens by inhibiting non-vesicular glutamate release...
  19. ncbi Group II metabotropic glutamate receptors modulate extracellular glutamate in the nucleus accumbens
    Zheng Xiong Xi
    Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Pharmacol Exp Ther 300:162-71. 2002
    ....

Research Grants11

  1. Cystine-Glu Antiporter & PCP Model of Schizophrenia
    David Baker; Fiscal Year: 2005
    ....
  2. Targeting System Xc- for the Treatment of Addiction
    David Baker; Fiscal Year: 2009
    ..abstract_text> ..
  3. Cystine-Glutamate Antiporters and Cocaine Reinstatement
    David Baker; Fiscal Year: 2007
    ..abstract_text> ..
  4. Cystine-Glutamate Antiporters and Cocaine Reinstatement
    David Baker; Fiscal Year: 2007
    ....
  5. Targeting System Xc- for the Treatment of Addiction
    John R Mantsch; Fiscal Year: 2010
    ..abstract_text> ..