Kathleen M Lukaszewicz

Summary

Affiliation: Marquette University
Country: USA

Publications

  1. doi request reprint Role of the CYP4A/20-HETE pathway in vascular dysfunction of the Dahl salt-sensitive rat
    Kathleen M Lukaszewicz
    Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Clin Sci (Lond) 124:695-700. 2013
  2. pmc Introgression of Brown Norway CYP4A genes on to the Dahl salt-sensitive background restores vascular function in SS-5(BN) consomic rats
    Kathleen M Lukaszewicz
    Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Clin Sci (Lond) 124:333-42. 2013

Detail Information

Publications2

  1. doi request reprint Role of the CYP4A/20-HETE pathway in vascular dysfunction of the Dahl salt-sensitive rat
    Kathleen M Lukaszewicz
    Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Clin Sci (Lond) 124:695-700. 2013
    ..The presence of this vicious cycle offers a possible explanation for the spiralling effects of elevated 20-HETE on the development of vascular dysfunction in this animal model...
  2. pmc Introgression of Brown Norway CYP4A genes on to the Dahl salt-sensitive background restores vascular function in SS-5(BN) consomic rats
    Kathleen M Lukaszewicz
    Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Clin Sci (Lond) 124:333-42. 2013
    ..These findings indicate that SS rats have an up-regulation of the CYP4A/20-HETE pathway resulting in elevated ROS (reactive oxygen species) and reduced NO bioavailability causing vascular dysfunction...