Hilary G Morrison

Summary

Affiliation: Marine Biological Laboratory
Country: USA

Publications

  1. pmc Rapid, low-input, low-bias construction of shotgun fragment libraries by high-density in vitro transposition
    Andrew Adey
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
    Genome Biol 11:R119. 2010
  2. pmc The Giardia lamblia vsp gene repertoire: characteristics, genomic organization, and evolution
    Rodney D Adam
    Departments of Medicine and Immunobiology, University of Arizona College of Medicine, Tucson, AZ, USA
    BMC Genomics 11:424. 2010
  3. ncbi request reprint Genomic minimalism in the early diverging intestinal parasite Giardia lamblia
    Hilary G Morrison
    Marine Biological Laboratory, Woods Hole, MA 02543 1015, USA
    Science 317:1921-6. 2007
  4. ncbi request reprint Inferring protein function from genomic sequence: Giardia lamblia expresses a phosphatidylinositol kinase-related kinase similar to yeast and mammalian TOR
    Hilary G Morrison
    Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, 7 MBL Street, Woods Hole, MA 02543 1015, USA
    Comp Biochem Physiol B Biochem Mol Biol 133:477-91. 2002
  5. pmc Effect of PCR amplicon size on assessments of clone library microbial diversity and community structure
    Julie A Huber
    Josephine Bay Paul Center, Marine Biological Laboratory, Woods Hole, MA 02543, USA
    Environ Microbiol 11:1292-302. 2009
  6. ncbi request reprint Microbial population structures in the deep marine biosphere
    Julie A Huber
    Josephine Bay Paul Center, Marine Biological Laboratory, 7 MBL Street, Woods Hole, MA 02543, USA
    Science 318:97-100. 2007
  7. pmc Ironing out the wrinkles in the rare biosphere through improved OTU clustering
    Susan M Huse
    Josephine Bay Paul Center, Marine Biological Laboratory at Woods Hole, 7 MBL Street, Woods Hole, MA 02543, USA
    Environ Microbiol 12:1889-98. 2010
  8. pmc Salt marsh sediment diversity: a test of the variability of the rare biosphere among environmental replicates
    Jennifer L Bowen
    The Ecosystems Center, Marine Biological Laboratory, Woods Hole, MA, USA
    ISME J 6:2014-23. 2012
  9. pmc Accuracy and quality of massively parallel DNA pyrosequencing
    Susan M Huse
    Josephine Bay Paul Center, Marine Biological Laboratory at Woods Hole, MBL Street, Woods Hole, MA 02543, USA
    Genome Biol 8:R143. 2007
  10. pmc Microbial community composition in sediments resists perturbation by nutrient enrichment
    Jennifer L Bowen
    The Ecosystems Center, Marine Biological Laboratory, Woods Hole, MA, USA
    ISME J 5:1540-8. 2011

Collaborators

Detail Information

Publications22

  1. pmc Rapid, low-input, low-bias construction of shotgun fragment libraries by high-density in vitro transposition
    Andrew Adey
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
    Genome Biol 11:R119. 2010
    ..We also extend its capabilities by developing protocols for sub-nanogram library construction, exome capture from 50 ng of input DNA, PCR-free and colony PCR library construction, and 96-plex sample indexing...
  2. pmc The Giardia lamblia vsp gene repertoire: characteristics, genomic organization, and evolution
    Rodney D Adam
    Departments of Medicine and Immunobiology, University of Arizona College of Medicine, Tucson, AZ, USA
    BMC Genomics 11:424. 2010
    ..The variable expression of the variant-specific surface protein (VSP) genes may contribute to this prolonged infection. Only one is expressed at a time, and switching expression from one gene to another occurs by an epigenetic mechanism...
  3. ncbi request reprint Genomic minimalism in the early diverging intestinal parasite Giardia lamblia
    Hilary G Morrison
    Marine Biological Laboratory, Woods Hole, MA 02543 1015, USA
    Science 317:1921-6. 2007
    ..This genome sequence will not only be valuable for investigating the evolution of eukaryotes, but will also be applied to the search for new therapeutics for this parasite...
  4. ncbi request reprint Inferring protein function from genomic sequence: Giardia lamblia expresses a phosphatidylinositol kinase-related kinase similar to yeast and mammalian TOR
    Hilary G Morrison
    Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, 7 MBL Street, Woods Hole, MA 02543 1015, USA
    Comp Biochem Physiol B Biochem Mol Biol 133:477-91. 2002
    ..Our investigation of the Giardia genome suggests that PIK-related kinases are of ancient origin and are highly conserved...
  5. pmc Effect of PCR amplicon size on assessments of clone library microbial diversity and community structure
    Julie A Huber
    Josephine Bay Paul Center, Marine Biological Laboratory, Woods Hole, MA 02543, USA
    Environ Microbiol 11:1292-302. 2009
    ....
  6. ncbi request reprint Microbial population structures in the deep marine biosphere
    Julie A Huber
    Josephine Bay Paul Center, Marine Biological Laboratory, 7 MBL Street, Woods Hole, MA 02543, USA
    Science 318:97-100. 2007
    ....
  7. pmc Ironing out the wrinkles in the rare biosphere through improved OTU clustering
    Susan M Huse
    Josephine Bay Paul Center, Marine Biological Laboratory at Woods Hole, 7 MBL Street, Woods Hole, MA 02543, USA
    Environ Microbiol 12:1889-98. 2010
    ..This new clustering method can reduce the OTU richness in environmental samples by as much as 30-60% but does not reduce the fraction of OTUs in long-tailed rank abundance curves that defines the rare biosphere...
  8. pmc Salt marsh sediment diversity: a test of the variability of the rare biosphere among environmental replicates
    Jennifer L Bowen
    The Ecosystems Center, Marine Biological Laboratory, Woods Hole, MA, USA
    ISME J 6:2014-23. 2012
    ..These results demonstrate that deep sequencing of 16s tags is well suited to distinguish site-specific similarities and differences among rare taxa and is a valuable tool for hypothesis testing in microbial ecology...
  9. pmc Accuracy and quality of massively parallel DNA pyrosequencing
    Susan M Huse
    Josephine Bay Paul Center, Marine Biological Laboratory at Woods Hole, MBL Street, Woods Hole, MA 02543, USA
    Genome Biol 8:R143. 2007
    ....
  10. pmc Microbial community composition in sediments resists perturbation by nutrient enrichment
    Jennifer L Bowen
    The Ecosystems Center, Marine Biological Laboratory, Woods Hole, MA, USA
    ISME J 5:1540-8. 2011
    ....
  11. pmc A filtering method to generate high quality short reads using illumina paired-end technology
    A Murat Eren
    Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, Woods Hole, Massachusetts, USA
    PLoS ONE 8:e66643. 2013
    ..The open-source implementation of this algorithm in Python programming language with user instructions can be obtained from https://github.com/meren/illumina-utils. ..
  12. pmc Microbial diversity in the deep sea and the underexplored "rare biosphere"
    Mitchell L Sogin
    Josephine Bay Paul Center, Marine Biological Laboratory at Woods Hole, 7 MBL Street, Woods Hole, MA 02543, USA
    Proc Natl Acad Sci U S A 103:12115-20. 2006
    ..Members of the rare biosphere are highly divergent from each other and, at different times in earth's history, may have had a profound impact on shaping planetary processes...
  13. ncbi request reprint Cloning and analysis of the CYP1A promoter from the atlantic killifish (Fundulus heteroclitus)
    Wade H Powell
    Marine Biological Laboratory, Woods Hole, MA, USA
    Mar Environ Res 58:119-24. 2004
    ..These studies may ultimately shed light on the importance of P4501A activity in xenobiotic toxicity...
  14. ncbi request reprint Characterisation of the subtelomeric regions of Giardia lamblia genome isolate WBC6
    Anjali Prabhu
    Department of Immunobiology, University of Arizona College of Medicine, 1501 N Campbell, Tucson, AZ 85724 5049, USA
    Int J Parasitol 37:503-13. 2007
    ..These studies of the subtelomeric regions of Giardia may contribute to our understanding of the factors that maintain stability, while allowing diversity in chromosome structure...
  15. pmc Evidence for lateral transfer of genes encoding ferredoxins, nitroreductases, NADH oxidase, and alcohol dehydrogenase 3 from anaerobic prokaryotes to Giardia lamblia and Entamoeba histolytica
    Julie E J Nixon
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Eukaryot Cell 1:181-90. 2002
    ..In further support of lateral transfer, the G. lamblia NADH oxidase and adh3 genes appeared to have an evolutionary history distinct from those of E. histolytica...
  16. pmc Evolution of eukaryotic transcription: insights from the genome of Giardia lamblia
    Aaron A Best
    Department of Microbiology, University of Illinois at Urbana Champaign, B103 Chemical and Life Sciences Laboratory, Urbana, Illinois 61801, USA
    Genome Res 14:1537-47. 2004
    ..Consequently, Giardia is predicted to be unique in many aspects of transcription initiation with respect to paradigms derived from studies in crown eukaryotes...
  17. ncbi request reprint Annexin-like alpha giardins: a new cytoskeletal gene family in Giardia lamblia
    Malin E L Weiland
    Microbiology and Tumor Biology Center, Karolinska Institutet, Stockholm, Sweden
    Int J Parasitol 35:617-26. 2005
    ..These localisation experiments suggest alpha-giardins play a role in cell motility, attachment and membrane stability...
  18. ncbi request reprint Exploring the relationship between sequence similarity and accurate phylogenetic trees
    Brandi L Cantarel
    Department of Biochemistry and Molecular Genetics, University of Virginia, VA, USA
    Mol Biol Evol 23:2090-100. 2006
    ..Accuracy can be improved by combining genes from the same organism when creating species trees or by selecting protein families with the best bootstrap values in comprehensive studies...
  19. pmc A spliceosomal intron in Giardia lamblia
    Julie E J Nixon
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115 6018, USA
    Proc Natl Acad Sci U S A 99:3701-5. 2002
    ..If introns were added during eukaryotic evolution (the introns-late hypothesis), then these results push back the date of this event before the branching of G. lamblia...
  20. ncbi request reprint Myelin tetraspan family proteins but no non-tetraspan family proteins are present in the ascidian (Ciona intestinalis) genome
    Robert M Gould
    Department of Anatomy and Cell Biology, University of Illinois, Chicago, Illinois 60612, USA
    Biol Bull 209:49-66. 2005
    ..In contrast, no MBP, P0, or CNP homologs were found. These studies provide a framework for understanding how myelin proteins were recruited during evolution and how structural adaptations enabled them to play key roles in myelination...
  21. pmc Patterns of genome evolution among the microsporidian parasites Encephalitozoon cuniculi, Antonospora locustae and Enterocytozoon bieneusi
    Nicolas Corradi
    Department of Botany, Canadian Institute for Advanced Research, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 2:e1277. 2007
    ..It is therefore difficult to determine how conservation has been maintained through microsporidian evolution, and impossible to identify whether certain regions are more prone to genomic stasis...
  22. ncbi request reprint Calcium signaling in excystation of the early diverging eukaryote, Giardia lamblia
    David S Reiner
    Department of Pathology, University of California, San Diego, 92103, USA
    J Biol Chem 278:2533-40. 2003
    ..Thus, the basal bodies may be a cellular control center to coordinate the resumption of motility and cytokinesis in excystation...