Wen Shu Wu

Summary

Affiliation: Maine Medical Center
Country: USA

Publications

  1. pmc Efficient generation of fully reprogrammed human iPS cells via polycistronic retroviral vector and a new cocktail of chemical compounds
    Zhonghui Zhang
    Stem and Progenitor Cell Biology Program, Center for Molecular Medicine, Maine Medical Center Research Institute, Maine Medical Center, Scarborough, Maine, United States of America
    PLoS ONE 6:e26592. 2011
  2. pmc Deletion of proapoptotic Puma selectively protects hematopoietic stem and progenitor cells against high-dose radiation
    Lijian Shao
    COBRE in Stem Biology and Regenerative Medicine Center for Molecular Medicine, Maine Medical Center Research Institute, Maine Medical Center, Scarborough, ME, USA
    Blood 115:4707-14. 2010
  3. pmc Slug deficiency enhances self-renewal of hematopoietic stem cells during hematopoietic regeneration
    Yan Sun
    Center of Biomedical Research Excellence COBRE in Stem Biology and Regenerative Medicine, Center for Molecular Medicine, Maine Medical Center Research Institute, Maine Medical Center, Scarborough, ME, USA
    Blood 115:1709-17. 2010
  4. pmc Bcl-xL enhances single-cell survival and expansion of human embryonic stem cells without affecting self-renewal
    Hao Bai
    Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME 04074, USA
    Stem Cell Res 8:26-37. 2012
  5. pmc BMP4 regulates vascular progenitor development in human embryonic stem cells through a Smad-dependent pathway
    Hao Bai
    Maine Medical Center, Maine Medical Center Research Institute, Scarborough, Maine 04074, USA
    J Cell Biochem 109:363-74. 2010
  6. pmc Gene-delivery systems for iPS cell generation
    Lijian Shao
    Maine Medical Center Research Institute, Maine Medical Center, COBRE in Stem Biology and Regenerative Medicine, 81 Research Drive, Scarborough, Maine 04074, USA
    Expert Opin Biol Ther 10:231-42. 2010
  7. pmc Generation of iPS cells using defined factors linked via the self-cleaving 2A sequences in a single open reading frame
    Lijian Shao
    Center for Molecular Medicine, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074, USA
    Cell Res 19:296-306. 2009
  8. pmc SLUG promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis
    Berna Uygur
    Center for Molecular Medicine, MMC Research Institute, Maine Medical Center, Scarborough, ME 04074, USA
    Mol Cancer 10:139. 2011

Collaborators

  • Yan Sun
  • Zhijian Qian
  • Yong Guang Yang
  • Jun Liu
  • Berna Uygur
  • Lijian Shao
  • Hao Bai
  • Zack Z Wang
  • Zhonghui Zhang
  • Yongxing Gao
  • Melanie Arzigian
  • Wei Feng
  • Christopher Malcosky
  • Yong Xing Gao
  • Kang Chen
  • Yin Liang Xie
  • ALBERT GORDON
  • A Thomas Look
  • Zailong Cai
  • Don M Wojchowski
  • Caroline Currie
  • Rafael Gama
  • Lucy Liaw
  • Zack Wang
  • Jaejung Kim

Detail Information

Publications8

  1. pmc Efficient generation of fully reprogrammed human iPS cells via polycistronic retroviral vector and a new cocktail of chemical compounds
    Zhonghui Zhang
    Stem and Progenitor Cell Biology Program, Center for Molecular Medicine, Maine Medical Center Research Institute, Maine Medical Center, Scarborough, Maine, United States of America
    PLoS ONE 6:e26592. 2011
    ....
  2. pmc Deletion of proapoptotic Puma selectively protects hematopoietic stem and progenitor cells against high-dose radiation
    Lijian Shao
    COBRE in Stem Biology and Regenerative Medicine Center for Molecular Medicine, Maine Medical Center Research Institute, Maine Medical Center, Scarborough, ME, USA
    Blood 115:4707-14. 2010
    ..Together, our data indicate that selective targeting of p53 downstream apoptotic targets may represent a novel strategy to protecting HSCs and HPCs in patients undergoing intensive cancer radiotherapy and chemotherapy...
  3. pmc Slug deficiency enhances self-renewal of hematopoietic stem cells during hematopoietic regeneration
    Yan Sun
    Center of Biomedical Research Excellence COBRE in Stem Biology and Regenerative Medicine, Center for Molecular Medicine, Maine Medical Center Research Institute, Maine Medical Center, Scarborough, ME, USA
    Blood 115:1709-17. 2010
    ..Our data suggest that inhibition of Slug in HSCs may present a novel strategy for accelerating hematopoietic recovery, thus providing therapeutic benefits for patients after clinical myelosuppressive treatment...
  4. pmc Bcl-xL enhances single-cell survival and expansion of human embryonic stem cells without affecting self-renewal
    Hao Bai
    Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME 04074, USA
    Stem Cell Res 8:26-37. 2012
    ....
  5. pmc BMP4 regulates vascular progenitor development in human embryonic stem cells through a Smad-dependent pathway
    Hao Bai
    Maine Medical Center, Maine Medical Center Research Institute, Scarborough, Maine 04074, USA
    J Cell Biochem 109:363-74. 2010
    ..Our findings provide new insight into how pluripotent hESCs differentiate into vascular cells...
  6. pmc Gene-delivery systems for iPS cell generation
    Lijian Shao
    Maine Medical Center Research Institute, Maine Medical Center, COBRE in Stem Biology and Regenerative Medicine, 81 Research Drive, Scarborough, Maine 04074, USA
    Expert Opin Biol Ther 10:231-42. 2010
    ..We include pertinent literature published between 2006 and the present...
  7. pmc Generation of iPS cells using defined factors linked via the self-cleaving 2A sequences in a single open reading frame
    Lijian Shao
    Center for Molecular Medicine, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074, USA
    Cell Res 19:296-306. 2009
    ..More importantly, when delivered by non-integrating gene-delivery systems, this re-engineered single ORF will facilitate efficient generation of human iPS cells free of genetic modifications...
  8. pmc SLUG promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis
    Berna Uygur
    Center for Molecular Medicine, MMC Research Institute, Maine Medical Center, Scarborough, ME 04074, USA
    Mol Cancer 10:139. 2011
    ..SLUG is a zinc-finger transcription factor of the Snail/Slug zinc-finger family that plays a role in migration and invasion of tumor cells. Mechanisms by which SLUG promotes migration and invasion in prostate cancers remain elusive...