David Clark

..Combining the strengths of these two samples might offset their limitations...

..Hazard regression (HR) models might therefore be more useful than logistic regression (LR) models for analysis of trauma mortality, especially when treatment effects at different time points are of interest...

..The distribution of survival times after injury has been described as "trimodal," but several studies have not confirmed this. The purpose of this study was to clarify the distribution of survival times after injury...

..To describe characteristics and short-term outcomes of Medicare patients hospitalized after injuries in 1999...

..We evaluated the generalizability of Medicare fee-for-service data for patients hospitalized with injuries...

..Major changes have occurred in populations served by trauma systems. Preventing injuries in the elderly is increasingly important. Accurate evaluation of cost-effectiveness in the elderly must include outcomes from SNF...

..Along with occasional misclassification in some states, the decrease in cases transported only to be pronounced DOA could explain why FARS data show a decrease in deaths after hospital transport...

..To determine whether the Barell matrix (Inj Prev 2002;8:91-6) could effectively categorize injuries by severity...

..Using hospital length of stay (LOS) to measure trauma care efficiency is complicated by short LOS resulting from early mortality or transfer to long-term care (LTC)...

..To evaluate whether survival of older patients with severe injuries is positively associated with initial presentation to high-volume trauma hospitals...

..Because it would thus improve critical care practice, SI should be increasingly accepted in the United States and especially promoted in the ICU...

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..The presence of a state trauma system did not measurably affect mortality. After controlling for VMT and southern location, state population density was a moderately strong predictor of rural but not urban traffic mortality rates...

..Risk adjustment methods are needed for population-based studies of injured patients...

..R. 2.10, 95% C.I. 1.62-2.73). The excess risk for residents of rural areas to die in traffic crashes can be attributed in part to post-crash factors...

..Whatever techniques are used, researchers must realize that the combination of data sources entails additional ethical obligations beyond the use of each source alone...

..The use of mechanical circulatory support (MCS) during repair of traumatic aortic injuries is associated with a decreased incidence of postoperative paraplegia and mortality...

..At least three prior studies have used declining mortality rates derived from FARS as evidence of regional trauma system effectiveness...

..CONCLUSIONS: Piecewise exponential models may be useful in predicting LOS, especially if determinants of mortality are separated from determinants of discharge alive...

..An increasing number of older patients are being hospitalized with traumatic brain injury (TBI). Knowledge of their expected long-term survival may be useful in making clinical decisions...

..To estimate the reduction in traffic mortality in the United States that would result from an automatic crash notification (ACN) system...

..This study details the feasibility and acceptance of TQIP among the participating centers...

..We sought to evaluate how survival of older patients with injuries differs by geographic region within the United States...

..Database queries produced comparative hospital statistics and identification of questionable outcomes. CONCLUSION: Record linkage allows inexpensive description of an inclusive trauma system and may contribute to quality improvement...

..Rates of operative intervention were lower at the trauma hospitals despite higher injury severity. Frequency of delayed intervention was low and did not increase with lower operative rate...

..To provide a method for any hospital to evaluate patient mortality using a hierarchical risk-adjustment equation derived from a reference sample...

..Survival until a fixed time after injury is a more useful outcome variable than survival until hospital discharge...

..The patient was treated with 3 months of oral anticoagulation alone...

..We compared injury records from a large administrative database and the National Trauma Data Bank (NTDB) with the goal of furthering the understanding of their respective limitations...

..More potent compounds were identified by follow-up searches around the initial hit. A proposed binding mode for compound 12 in a homology model of the MCH-1R is also presented...

..Currently, a particularly significant trend is the move towards 'off-shoring', which promises to drive further changes in this rapidly evolving market in the near future...

..This article will address these key considerations for the development and application of in silico methods in drug discovery...

..This project is designed to produce a credible and verifiable data management structure and analytic methodology that can be used for the continuing evaluation of trauma care by the ACS, AHRQ, and others. ..

..This will enable us to distinguish between the impact of level of trauma system development and other factors affecting the disparity in rural and urban trauma mortality. ..

..This will enable us to distinguish between the impact of level of trauma system development and other factors affecting the disparity in rural and urban trauma mortality. ..