Steven G Pavlakis
Affiliation: Maimonides Medical Center
- Pediatric stroke: Opportunities and challenges in planning clinical trialsSteven G Pavlakis
Maimonides Infants and Children s Hospital, Developmental Medicine and Child Neurology, Brooklyn, New York 11219, USA
Pediatr Neurol 34:433-5. 2006..We should strive for enrollment and outcome results in pediatric stroke similar to those found in pediatric oncology trials...
- Lessons from adult stroke trialsSteven G Pavlakis
Mount Sinai School of Medicine, New York, New York, USA
Pediatr Neurol 34:446-9. 2006..Because clinical trials, more often than not, fail to give positive (effective treatment) results, it seems reasonable to attempt to learn from others' past experiences before initiating pediatric stroke trials...
- Transcranial doppler ultrasonography (TCD) in infants with sickle cell anemia: baseline data from the BABY HUG trialSteven G Pavlakis
Maimonides Infants and Children s Hospital Mount Sinai School of Medicine, Brooklyn, New York 11219, USA
Pediatr Blood Cancer 54:256-9. 2010..Transcranial Doppler ultrasonography (TCD) is used to predict stroke risk in children with sickle cell anemia (SCA), but has not been adequately studied in children under age 2 years...
- Hypertension impairs vascular reactivity in the pediatric brainLinda J Wong
Department of Pediatrics, Maimonides Infants and Children s Hospital, 977 48th Street, Brooklyn, NY 11219, USA
Stroke 42:1834-8. 2011..The objective of this study was to investigate cerebrovascular abnormalities in hypertensive children and adolescents...
- Primary hypertension and neurocognitive and executive functioning in school-age childrenJuan C Kupferman
Division of Pediatric Nephrology and Hypertension, Department of Pediatrics, Maimonides Medical Center, 977 48th Street, Brooklyn, NY 11219, USA
Pediatr Nephrol 28:401-8. 2013..Larger, prospective studies are needed to confirm and further explore these emerging but preliminary findings...
- Executive function and cerebrovascular reactivity in pediatric hypertensionMaria A Ostrovskaya
Center for Brain and Behavior, Maimonides Medical Center, Brooklyn, NY, USA
J Child Neurol 30:543-6. 2015..53, P = .05). Children with hypertension have decreased executive function, and this correlates to low transcranial Doppler-reactivity slopes, suggesting that the brain is a target organ in hypertensive children. ..
- Brain hypoperfusion in a girl with systemic lupus erythematosusLinda J Wong
Department of Pediatric Neurology, Maimonides Infants and Children s Hospital, Brooklyn, New York 11219, USA
Pediatr Neurol 45:335-7. 2011....
- Newborn brain infarction: clinical aspects and magnetic resonance imagingAkila Venkataraman
Department of Pediatrics, Maimonides Medical Center, Brooklyn, NY 121219, USA
CNS Spectr 9:436-44. 2004....
- Lacunar stroke and masked hypertension in an adolescent maleJuan C Kupferman
Division of Pediatric Nephrology, Department of Pediatrics, Maimonides Infants and Children s Hospital, Brooklyn, New York 11219, and the Mount Sinai School of Medicine, New York, New York, USA
Pediatr Neurol 36:125-7. 2007..Evaluation for possible hypertension should be undertaken thoroughly to identify children who may benefit from antihypertensive therapy and therefore, prevent recurrences...
- The effects of hypertension on the paediatric brain: a justifiable concernMadhu Sharma
Department of Pediatrics, Maimonides Infants and Childrens Hospital, New York, NY, USA
Lancet Neurol 9:933-40. 2010..Furthermore, accurate biomarkers to define cognitive abnormalities and cerebral involvement need to be identified...
- Hemodynamic etiology of elevated flow velocity and stroke in sickle-cell diseaseIsak Prohovnik
Department of Psychiatry and Radiology, Mount Sinai School of Medicine, New York, New York 10029, USA
J Cereb Blood Flow Metab 29:803-10. 2009....
- MRI abnormalities of the brain in one-year-old children with sickle cell anemiaWinfred C Wang
Department of Hematology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
Pediatr Blood Cancer 51:643-6. 2008..We performed MRI examinations of the brain in infants with SCA, who were evaluated as part of the multicenter randomized double-blinded Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG)...
- Sickle cell disease: ischemia and seizuresMara Prengler
Neurosciences Unit, Institute of Child Health, University College London, London, United Kingdom
Ann Neurol 58:290-302. 2005..These findings suggest that vasculopathy and focal hypoperfusion may be factors in the development of sickle cell disease-associated seizures...
- Sickle cell disease: the neurological complicationsMara Prengler
Neurosciences Unit, Institute of Child Health, University College and Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
Ann Neurol 51:543-52. 2002..This complex disease underscores the potential intellectual and practical distance between the determination of molecular genetics and effective clinical application and therapeutics...