Kelly E Lyons

Summary

Country: USA

Publications

  1. doi Onset of dyskinesia with adjunct ropinirole prolonged-release or additional levodopa in early Parkinson's disease
    Ray L Watts
    Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0017, USA
    Mov Disord 25:858-66. 2010
  2. pmc A review of ropinirole prolonged release in Parkinson's disease
    Muhammad M Nashatizadeh
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Clin Interv Aging 4:179-86. 2009
  3. ncbi Long-term efficacy of globus pallidus stimulation for the treatment of Parkinson's disease
    Kelly E Lyons
    Department of Neurology, University of Miami Medical Center, Miami, Fla, USA
    Stereotact Funct Neurosurg 79:214-20. 2002
  4. doi An open-label conversion study of pramipexole to ropinirole prolonged release in Parkinson's disease
    Kelly E Lyons
    Department of Neurology, Parkinson s Disease and Movement Disorder Center, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Mov Disord 24:2121-7. 2009
  5. ncbi Surgical and hardware complications of subthalamic stimulation: a series of 160 procedures
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, 3599 Rainbow Blvd, Mailstop 2012, Kansas City, KS 66160, USA
    Neurology 63:612-6. 2004
  6. ncbi Subthalamic nucleus stimulation in Parkinson's disease patients intolerant to levodopa
    Kelly E Lyons
    University of Kansas Medical Center, Department of Neurology, Kansas City, KS 66160, USA
    Stereotact Funct Neurosurg 85:169-74. 2007
  7. ncbi Electronic motor function diary for patients with Parkinson's disease: a feasibility study
    Kelly E Lyons
    Parkinson s Disease and Movement Disorder Center, Department of Neurology, University of Kansas Medical Center, 3599 Rainbow Blvd, Mailstop 2012, Kansas City, KS 66160, USA
    Parkinsonism Relat Disord 13:304-7. 2007
  8. ncbi Efficacy and tolerability of levetiracetam in Parkinson disease patients with levodopa-induced dyskinesia
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, Kansas City, 66160, USA
    Clin Neuropharmacol 29:148-53. 2006
  9. ncbi Effects of bilateral subthalamic nucleus stimulation on sleep, daytime sleepiness, and early morning dystonia in patients with Parkinson disease
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Neurosurg 104:502-5. 2006
  10. ncbi Long-term benefits in quality of life provided by bilateral subthalamic stimulation in patients with Parkinson disease
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Neurosurg 103:252-5. 2005

Detail Information

Publications69

  1. doi Onset of dyskinesia with adjunct ropinirole prolonged-release or additional levodopa in early Parkinson's disease
    Ray L Watts
    Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0017, USA
    Mov Disord 25:858-66. 2010
    ..Ropinirole prolonged-release delayed the onset of dyskinesia with comparable efficacy to increased doses of levodopa in early PD patients not optimally controlled with levodopa...
  2. pmc A review of ropinirole prolonged release in Parkinson's disease
    Muhammad M Nashatizadeh
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Clin Interv Aging 4:179-86. 2009
    ..This manuscript briefly reviews the current pharmacological treatment options for PD and provides a more detailed review of the currently available data regarding ropinirole prolonged release as a treatment option for PD...
  3. ncbi Long-term efficacy of globus pallidus stimulation for the treatment of Parkinson's disease
    Kelly E Lyons
    Department of Neurology, University of Miami Medical Center, Miami, Fla, USA
    Stereotact Funct Neurosurg 79:214-20. 2002
    ..To determine the long-term efficacy and safety of globus pallidus internus (GPi) stimulation for Parkinson's disease (PD)...
  4. doi An open-label conversion study of pramipexole to ropinirole prolonged release in Parkinson's disease
    Kelly E Lyons
    Department of Neurology, Parkinson s Disease and Movement Disorder Center, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Mov Disord 24:2121-7. 2009
    ..A conversion ratio of 1 mg of pramipexole to 4 mg of ropinirole PR resulted in the fewest discontinuations of ropinirole PR, the fewest dose adjustments and the largest percentage of subjects that preferred ropinirole PR...
  5. ncbi Surgical and hardware complications of subthalamic stimulation: a series of 160 procedures
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, 3599 Rainbow Blvd, Mailstop 2012, Kansas City, KS 66160, USA
    Neurology 63:612-6. 2004
    ..To assess the surgical and hardware complications in a series of 81 consecutive patients undergoing subthalamic (STN) deep brain stimulation (DBS) for Parkinson disease (PD)...
  6. ncbi Subthalamic nucleus stimulation in Parkinson's disease patients intolerant to levodopa
    Kelly E Lyons
    University of Kansas Medical Center, Department of Neurology, Kansas City, KS 66160, USA
    Stereotact Funct Neurosurg 85:169-74. 2007
    ..In conclusion, although levodopa responsiveness is the best predictor for outcome after STN DBS, carefully selected PD patients intolerant to levodopa can have significant improvement...
  7. ncbi Electronic motor function diary for patients with Parkinson's disease: a feasibility study
    Kelly E Lyons
    Parkinson s Disease and Movement Disorder Center, Department of Neurology, University of Kansas Medical Center, 3599 Rainbow Blvd, Mailstop 2012, Kansas City, KS 66160, USA
    Parkinsonism Relat Disord 13:304-7. 2007
    ..Electronic diaries could be operated by PD patients, provided valuable information about response patterns and resulted in average response compliance of approximately 1h...
  8. ncbi Efficacy and tolerability of levetiracetam in Parkinson disease patients with levodopa-induced dyskinesia
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, Kansas City, 66160, USA
    Clin Neuropharmacol 29:148-53. 2006
    ..This open-label study was performed to evaluate the efficacy and tolerability of levetiracetam for levodopa-induced dyskinesia and its effect on motor functioning and quality of life in Parkinson disease (PD) patients...
  9. ncbi Effects of bilateral subthalamic nucleus stimulation on sleep, daytime sleepiness, and early morning dystonia in patients with Parkinson disease
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Neurosurg 104:502-5. 2006
    ....
  10. ncbi Long-term benefits in quality of life provided by bilateral subthalamic stimulation in patients with Parkinson disease
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Neurosurg 103:252-5. 2005
    ....
  11. ncbi Stimulation of the motor cortex for disabling essential tremor
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, 3599 Rainbow Blvd, Mailstop 2012, Kansas City, KS 66160, USA
    Clin Neurol Neurosurg 108:564-7. 2006
    ..To examine the safety and efficacy of targeted stimulation of the motor cortex as a treatment for essential tremor (ET)...
  12. ncbi Deep brain stimulation in Parkinson's disease
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, 3599 Rainbow Boulevard, Mailstop 2012, Kansas City, KS 66160, USA
    Curr Neurol Neurosci Rep 4:290-5. 2004
    ..Complications associated with DBS are related to the experience of the surgical center. Referring physicians and patients should be aware of the number of surgical procedures and complication rates of any prospective surgical center...
  13. ncbi Deep brain stimulation and essential tremor
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Clin Neurophysiol 21:2-5. 2004
    ..Deep brain stimulation of the thalamus is a safe and efficacious procedure and should be considered in patients with ET who experience medication-resistant disabling tremor...
  14. ncbi Conversion from sustained release carbidopa/levodopa to carbidopa/levodopa/entacapone (stalevo) in Parkinson disease patients
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, Kansas City, 66160, USA
    Clin Neuropharmacol 29:73-6. 2006
    ....
  15. doi Orally disintegrating selegiline in Parkinson patients with dopamine agonist-related adverse effects
    Kelly E Lyons
    University of Kansas Medical Center, Kansas City, KS 66160, USA
    Clin Neuropharmacol 33:5-10. 2010
    ....
  16. doi Pharmacotherapy of essential tremor : an overview of existing and upcoming agents
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    CNS Drugs 22:1037-45. 2008
    ..Several new drugs, including 1-octanol, sodium oxybate, dimethoxymethyl-diphenyl-barbituric acid (T-2000) and carisbamate, are currently under investigation for the treatment of essential tremor...
  17. doi Deep brain stimulation and tremor
    Kelly E Lyons
    Parkinson s Disease and Movement Disorder Center, Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Neurotherapeutics 5:331-8. 2008
    ....
  18. doi Treatment of early Parkinson's disease. Part 2
    Tanya Simuni
    Department of Neurology, Northwestern University, Parkinson s Disease and Movement Disorders Center, Chicago, Ill, USA
    Eur Neurol 61:206-15. 2009
    ..Part 2 of the article, presented here, reviews key data relevant to the assessment of potential neuroprotective therapies and the treatment of non-motor symptoms...
  19. ncbi Pharmacokinetic-pharmacodynamic crossover comparison of two levodopa extension strategies
    Peter A LeWitt
    Department of Neurology, Henry Ford Hospital and Wayne State University School of Medicine, Detroit, Michigan, USA
    Mov Disord 24:1319-24. 2009
    ..803), and "on state with nontroublesome dyskinesia" was 18% for CLE and 7% for CL-CR (P = 0.03). Despite less "off" time with CLE, both formulations demonstrated similar mean PK values and marked intersubject PK variability...
  20. ncbi Long-term evaluation of deep brain stimulation of the thalamus
    Rajesh Pahwa
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Neurosurg 104:506-12. 2006
    ..The aim of this study was to evaluate the long-term safety and efficacy of DBS of the ventralis intermedius nucleus (VIM) of the thalamus for PD and ET...
  21. doi Long-term benefits in quality of life after unilateral thalamic deep brain stimulation for essential tremor
    Jules M Nazzaro
    Department of Neurosurgery, University of Kansas Medical Center, Kansas City, KS 66160, USA
    J Neurosurg 117:156-61. 2012
    ..The goal of this study was to evaluate short- and long-term benefits in quality of life (QOL) after unilateral deep brain stimulation (DBS) for essential tremor (ET)...
  22. doi Treatment of early Parkinson's disease. Part 1
    Tanya Simuni
    Department of Neurology, Northwestern University, Parkinson s Disease and Movement Disorders Center, Chicago, Ill 60611, USA
    Eur Neurol 61:193-205. 2009
    ..Safety and tolerability data are also reviewed. Part 2 of the article reviews key findings relevant to the assessment of potential neuroprotective therapies and the treatment of non-motor symptoms...
  23. ncbi Postural tremor suppression is dependent on thalamic stimulation frequency
    Mwiza Ushe
    Department of Neurology, Washington University, St Louis, Missouri, USA
    Mov Disord 21:1290-2. 2006
    ....
  24. doi Randomized, double-blind, pilot evaluation of intravenous glutathione in Parkinson's disease
    Robert A Hauser
    Department of Neurology, University of South Florida, Tampa, Florida 33606, USA
    Mov Disord 24:979-83. 2009
    ..54). Glutathione was well tolerated and no safety concerns were identified. Preliminary efficacy data suggest the possibility of a mild symptomatic effect, but this remains to be evaluated in a larger study...
  25. ncbi Options in the treatment of motor fluctuations and dyskinesias in Parkinson's disease: a brief review
    Rajesh Pahwa
    Parkinson s Disease and Movement Disorder Center, University of Kansas Medical Center, 3599 Rainbow Boulevard, Mailstop 2012, Kansas City, KS 66160, USA
    Neurol Clin 22:S35-52. 2004
  26. ncbi Essential tremor: differential diagnosis and current therapy
    Rajesh Pahwa
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160 7314, USA
    Am J Med 115:134-42. 2003
    ..Patients with medication-resistant tremor may benefit from thalamotomy or deep brain stimulation of the thalamus. The use of medical and surgical therapies can provide benefit in up to 80% of patients with essential tremor...
  27. ncbi Ropinirole therapy for Parkinson's disease
    Rajesh Pahwa
    Department of Neurology, University of Kansas Medical Center, 3599 Rainbow Blvd, Kansas City, KS 66160, USA
    Expert Rev Neurother 4:581-8. 2004
    ..A once-daily formulation of ropinirole is currently in development that has the potential for greater convenience, improved tolerability and greater efficacy...
  28. doi The impact of bilateral subthalamic stimulation on non-motor symptoms of Parkinson's disease
    Jules M Nazzaro
    Department of Neurosurgery, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Parkinsonism Relat Disord 17:606-9. 2011
    ....
  29. ncbi Levetiracetam is not effective for essential tremor
    Rodger J Elble
    Department of Neurology, Southern Illinois University School of Medicine, Springfield, IL 62794 9643, USA
    Clin Neuropharmacol 30:350-6. 2007
    ..To determine if levetiracetam is efficacious in the treatment of essential tremor...
  30. doi Use of brain MRI after deep brain stimulation hardware implantation
    Jules M Nazzaro
    Department of Neurosurgery, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Int J Neurosci 120:176-83. 2010
    ..Rather, our data may contribute to further defining safe MRI scanning parameters that might ultimately be adopted in future product labeling as more centers report in detail their experiences...
  31. ncbi Levodopa-related wearing-off in Parkinson's disease: identification and management
    Rajesh Pahwa
    Department of Neurology, University of Kansas Medical Center, 3599 Rainbow Blvd, Kansas City, KS 66160, USA
    Curr Med Res Opin 25:841-9. 2009
    ..The initial complication is commonly wearing-off, which is the re-emergence of motor and non-motor symptoms before the next scheduled levodopa dose...
  32. ncbi The impact and management of nonmotor symptoms of Parkinson's disease
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA
    Am J Manag Care 17:S308-14. 2011
    ..In many cases, symptom-specific treatments are necessary to control nonmotor symptoms of PD...
  33. ncbi Preoperative clinical predictors of response to bilateral subthalamic stimulation in patients with Parkinson's disease
    Rajesh Pahwa
    Department of Neurology, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Stereotact Funct Neurosurg 83:80-3. 2005
    ..Younger age and a response to a supra-threshold levodopa challenge have been reported to predict a favorable response to bilateral subthalamic nucleus (STN) stimulation...
  34. ncbi Bilateral subthalamic stimulation in patients with Parkinson disease: long-term follow up
    Rajesh Pahwa
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Neurosurg 99:71-7. 2003
    ..Bilateral subthalamic nucleus (STN) stimulation is increasingly used in patients with advanced Parkinson disease (PD). This study was performed to evaluate the long-term efficacy and safety of bilateral STN stimulation in cases of PD...
  35. ncbi Freezing of gait after bilateral subthalamic nucleus stimulation for Parkinson's disease
    Justin T Davis
    University of Kansas Medical Center, Department of Neurology, 3599 Rainbow Blvd, Kansas City, KS 66160, USA
    Clin Neurol Neurosurg 108:461-4. 2006
    ..To determine the long-term effect of bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) on freezing of gait in Parkinson's disease patients...
  36. ncbi Future therapies for Parkinson's disease
    Robert A Hauser
    Department of Neurology, University of South Florida and Tampa General Healthcare, Tampa, FL 33606, USA
    Neurol Clin 22:S149-66. 2004
  37. ncbi Open-label trial regarding the use of acupuncture and yin tui na in Parkinson's disease outpatients: a pilot study on efficacy, tolerability, and quality of life
    Marty L Eng
    University of Kansas Medical Center, University of Kansas, School of Pharmacy, Department of Pharmacy Practice, Kansas City, KS 66160 7231, USA
    J Altern Complement Med 12:395-9. 2006
    ..This study evaluates the effects of sequential tui na massage, acupuncture, and instrument-delivered qigong for patients with Parkinson disease (PD) over a 6-month period...
  38. ncbi Quality of life in Essential Tremor Questionnaire (QUEST): development and initial validation
    Alexander I Troster
    Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7025, USA
    Parkinsonism Relat Disord 11:367-73. 2005
    ..We sought to develop an ET-specific measure that might be more sensitive, acceptable to patients, relatively brief, and easily used...
  39. pmc Hospitalization in Parkinson disease: a survey of National Parkinson Foundation Centers
    Kelvin L Chou
    Department of Neurology, University of Michigan, Ann Arbor, MI 48109 5316, USA
    Parkinsonism Relat Disord 17:440-5. 2011
    ..To explore current practices and opinions regarding hospital management of Parkinson disease (PD) patients in specialized PD Centers...
  40. ncbi Benefits and risks of pharmacological treatments for essential tremor
    Kelly E Lyons
    University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Drug Saf 26:461-81. 2003
    ..The use of medication and/or surgery can provide adequate tremor control in the majority of the patients...
  41. ncbi Effect of levodopa treatment for parkinsonism in welders: A double-blind study
    William C Koller
    Department of Neurology, The Mount Sinai School of Medicine, New York, NY, USA
    Neurology 62:730-3. 2004
    ..Manganese is known to cause a parkinsonian syndrome similar clinically to Parkinson disease (PD). L-Dopa responsiveness is a hallmark of PD; however, L-dopa's effect on manganese-induced parkinsonism is not well defined...
  42. doi Understanding verbal fluency in healthy aging, Alzheimer's disease, and Parkinson's disease
    Joan McDowd
    Landon Center on Aging, University of Kansas Medical Center, Kansas City, MO, USA
    Neuropsychology 25:210-25. 2011
    ..The goal of the present study was to identify the cognitive components underlying fluency performance...
  43. doi Deep brain stimulation for essential tremor
    Jules M Nazzaro
    Department of Neurosurgery, University of Kansas Medical Center, Kansas City, KS, USA Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS, USA
    Handb Clin Neurol 116:155-66. 2013
    ..Investigations of DBS of other brain target areas for essential tremor, such as the posterior subthalamic area and the subthalamic nucleus, are ongoing. ..
  44. doi Randomized trial of IPX066, carbidopa/levodopa extended release, in early Parkinson's disease
    Rajesh Pahwa
    University of Kansas Medical Center, Kansas City, KS, USA Electronic address
    Parkinsonism Relat Disord 20:142-8. 2014
    ..The objective was to assess the efficacy, safety, and impact on quality of life of IPX066 in the treatment of levodopa-naive Parkinson's disease (PD) patients...
  45. doi Postural sway in patients with mild to moderate Parkinson's disease
    Antonis P Stylianou
    Landon Center on Aging, University of Kansas Medical Center, Kansas City, KS, USA
    Int J Neurosci 121:614-21. 2011
    ..The results suggest that the ML direction is a successful discriminator between PD and age-matched controls and that the interaction between ML and AP directions should be considered in the method used to quantify postural instability...
  46. pmc Impact of belief in neuroprotection on therapeutic intervention in Parkinson's disease
    Rodger J Elble
    Department of Neurology, Southern Illinois University School of Medicine, Springfield, Illinois, USA
    Mov Disord 25:1082-6. 2010
    ..We found the investigators' level of confidence in these agents had no effect on the time to symptomatic therapy or on the change in UPDRS during 12 months of treatment...
  47. doi Generic versus branded pharmacotherapy in Parkinson's disease: does it matter? A review
    Criscely L Go
    Department of Neurology, University of Florida, McKnight Brain Institute, Movement Disorders Center, 100 S Newell Drive, Gainesville, FL 32611, USA
    Parkinsonism Relat Disord 17:308-12. 2011
    ..Currently, in the U.S, and in many countries around the world, there is no obligation for payers to respect these types of patient specific bedside trials, and there has been no standardization of the process...
  48. doi Head positioning and risk of pneumocephalus, air embolism, and hemorrhage during subthalamic deep brain stimulation surgery
    Jules M Nazzaro
    Department of Neurosurgery, University of Kansas Medical Center, Kansas City, 66160, USA
    Acta Neurochir (Wien) 152:2047-52. 2010
    ....
  49. ncbi Early diagnosis of Parkinson's disease: recommendations from diagnostic clinical guidelines
    Rajesh Pahwa
    University of Kansas Medical Center, 3599 Rainbow Blvd, Kansas City, KS 66160, USA
    Am J Manag Care 16:S94-9. 2010
    ..This article reviews and summarizes published recommendations for the clinical diagnosis of PD...
  50. ncbi Effect of stimulation frequency on tremor suppression in essential tremor
    Mwiza Ushe
    Department of Neurology, Washington University in St Louis, St Louis, Missouri, USA
    Mov Disord 19:1163-8. 2004
    ..Second, thalamic DBS provides tremor benefit in a graded manner and is not an all-or-nothing phenomenon...
  51. ncbi Thalamic stimulation for midbrain tremor after partial hemangioma resection
    Rajesh Pahwa
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Mov Disord 17:404-7. 2002
    ..We describe a patient with disabling medication-resistant midbrain tremor developed after partial hemangioma resection, who responded to deep brain stimulation of the thalamus...
  52. doi Deep brain stimulation lead-contact heating during 3T MRI: single- versus dual-channel pulse generator configurations
    Jules M Nazzaro
    1Department of Neurosurgery, University of Kansas Medical Center, Kansas City, KS, USA
    Int J Neurosci 124:166-74. 2014
    ..Magnetic resonance imaging (MRI) after deep brain stimulation (DBS) carries the risk of heating at the lead-contacts within the brain...
  53. doi Outcomes of rotigotine clinical trials: effects on motor and nonmotor symptoms of Parkinson's disease
    Kelly E Lyons
    Department of Neurology, University of Kansas Medical Center, 3599 Rainbow Boulevard, Kansas City, KS 66160, USA
    Neurol Clin 31:S51-9. 2013
    ..Rotigotine has been shown in large, controlled studies to be safe and efficacious for the treatment of motor and some nonmotor symptoms of early and advanced PD. ..
  54. doi Diagnosis and initiation of treatment in Parkinson's disease
    Kelly E Lyons
    Parkinson s Disease and Movement Disorder Center, Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Int J Neurosci 121:27-36. 2011
    ....
  55. ncbi Mirtazapine in essential tremor: a double-blind, placebo-controlled pilot study
    Rajesh Pahwa
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas, USA
    Mov Disord 18:584-7. 2003
    ..We conclude that the majority of the ET patients do not benefit from mirtazapine. Mirtazapine has significant adverse effects and should be used cautiously in ET patients...
  56. pmc The importance of testing deep brain stimulation lead impedances before final lead implantation
    Jules M Nazzaro
    Department of Neurosurgery, University of Kansas Medical Center, Kansas City, KS, USA
    Surg Neurol Int 2:131. 2011
    ..This report suggests that neurosurgeons need to be aware and consider the use of the newly available DBS testing equipment...
  57. ncbi Treatment of early Parkinson's disease
    Rajesh Pahwa
    A National Parkinson Foundation Center of Excellence, University of Kansas Medical Center, Kansas City, Kansas, USA
    Curr Opin Neurol 27:442-9. 2014
    ..This review summarizes currently available treatment options and treatment strategies, investigational treatments, and the importance of exercise for early Parkinson's disease...
  58. ncbi Effect of motor improvement on quality of life following subthalamic stimulation is mediated by changes in depressive symptomatology
    Alexander I Troster
    Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
    Stereotact Funct Neurosurg 80:43-7. 2003
    ..Because depression is a potent correlate of QOL, and STN-DBS may be associated with changes in mood, this study sought to determine whether QOL improvement is a direct or indirect consequence of motor improvement...
  59. ncbi Deep brain stimulation: postoperative issues
    Gunther Deuschl
    Department of Neurology, Christian Albrechts Universitat Kiel, Kiel, Germany
    Mov Disord 21:S219-37. 2006
    ..The report has been endorsed by the Scientific Issues Committee of the Movement Disorder Society and the American Society of Stereotactic and Functional Neurosurgery...
  60. ncbi Subthalamic nucleus deep brain stimulation: summary and meta-analysis of outcomes
    Galit Kleiner-Fisman
    Parkinson s Disease Research Education and Clinical Center, Philadelphia VA Hospital, Philadelphia, Pennsylvania 19104, USA
    Mov Disord 21:S290-304. 2006
    ..These data provide an estimate of the magnitude of the treatment effects and emphasize the need for controlled and randomized studies...
  61. ncbi Pulse width is associated with cognitive decline after thalamic stimulation for essential tremor
    Steven Paul Woods
    Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Box 356560, 1959 NE Pacific Street, Seattle, WA 98195 6560, USA
    Parkinsonism Relat Disord 9:295-300. 2003
    ..Findings indicate that although relatively higher PW settings might afford optimal tremor control in some patients, the corresponding risk of mild, probably often subclinical, cognitive morbidity must be weighed accordingly...
  62. ncbi Deep brain stimulation: preoperative issues
    Anthony E Lang
    Department of Neurology, Toronto Western Hospital, Toronto, Ontario, Canada
    Mov Disord 21:S171-96. 2006
    ..It outlines answers to a series of questions developed to address all aspects of deep brain stimulation preoperative decision-making...
  63. pmc Reduced Purkinje cell number in essential tremor: a postmortem study
    Jordan E Axelrad
    Gertrude H Sergievsky Center, Columbia University, New York, New York, USA
    Arch Neurol 65:101-7. 2008
    ..In recent postmortem studies, we documented increased numbers of torpedoes (Purkinje cell axonal swellings) in ET patients without Lewy bodies. Purkinje cell loss, however, has never been rigorously assessed...
  64. ncbi Neuropathological changes in essential tremor: 33 cases compared with 21 controls
    Elan D Louis
    GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, USA
    Brain 130:3297-307. 2007
    ..The majority have cerebellar changes without Lewy bodies; a smaller proportion has brainstem Lewy bodies. The clinical differences between cases with versus without Lewy bodies require additional study...
  65. ncbi Advanced Parkinson disease treated with rotigotine transdermal system: PREFER Study
    Peter A LeWitt
    Clinical Neuroscience Center, Southfield, MI 48034, USA
    Neurology 68:1262-7. 2007
    ..In patients experiencing motor fluctuations, a major treatment challenge is the reduction of "off" time, particularly upon awakening. Rotigotine (Neupro) is a novel dopaminergic agonist with 24-hour transdermal delivery...
  66. ncbi Association study of Parkin gene polymorphisms with idiopathic Parkinson disease
    Sofia A Oliveira
    Department of Medicine and Center for Human Genetics, Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, NC
    Arch Neurol 60:975-80. 2003
    ..However, previous case-control studies have reported conflicting results regarding the role of more common Parkin polymorphisms as susceptibility alleles for idiopathic PD...
  67. ncbi Bilateral pallidotomy for severe dystonia in an 18-month-old child with glutaric aciduria
    Goran Rakocevic
    National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA
    Stereotact Funct Neurosurg 82:80-3. 2004
    ..The surgery improved dystonic symptoms, especially pain in this child with minor complications related to the procedure. Pallidotomy is a reasonable option for children with dystonic symptoms secondary to glutaric aciduria...
  68. ncbi Deep brain stimulation for Parkinson's disease
    Alim Louis Benabid
    Grenoble, France
    Mov Disord 21:S168-70. 2006
  69. ncbi Prevalence of bone mineral density screening in Parkinson's disease clinic outpatients
    Marty L Eng
    Mov Disord 21:2265-6. 2006