P Stiff

Summary

Affiliation: Loyola University Medical Center
Country: USA

Publications

  1. doi request reprint Prevention of nausea and vomiting associated with stem cell transplant: results of a prospective, randomized trial of aprepitant used with highly emetogenic preparative regimens
    Patrick J Stiff
    Bone Marrow Transplant Program, Department of Pharmacy, University Medical Center, Maywood, Illinois, USA
    Biol Blood Marrow Transplant 19:49-55.e1. 2013
  2. ncbi request reprint Palifermin reduces patient-reported mouth and throat soreness and improves patient functioning in the hematopoietic stem-cell transplantation setting
    Patrick J Stiff
    Cardinal Bernardin Cancer Center, Maywood, IL 60153, USA
    J Clin Oncol 24:5186-93. 2006
  3. ncbi request reprint Reliability and validity of a patient self-administered daily questionnaire to assess impact of oral mucositis (OM) on pain and daily functioning in patients undergoing autologous hematopoietic stem cell transplantation (HSCT)
    P J Stiff
    Cardinal Bernardin Cancer Center, Loyola University, Maywood, IL 60153, USA
    Bone Marrow Transplant 37:393-401. 2006
  4. ncbi request reprint Patients' understanding of disease status and treatment plan at initial hematopoietic stem cell transplantation consultation
    P J Stiff
    Department of Medicine, Loyola University Medical Center, Maywood, IL, USA
    Bone Marrow Transplant 37:479-84. 2006
  5. ncbi request reprint Autologous hematopoietic stem cell transplants that utilize total body irradiation can safely be carried out entirely on an outpatient basis
    P Stiff
    Bone Marrow Transplant Program, Loyola University Medical Center, Maywood, IL 60153, USA
    Bone Marrow Transplant 38:757-64. 2006
  6. ncbi request reprint Mucositis: continuing progress for a continuing need
    Patrick J Stiff
    Division of Hematology Oncology, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA
    J Support Oncol 5:47-62. 2007
  7. doi request reprint Treatment with plerixafor in non-Hodgkin's lymphoma and multiple myeloma patients to increase the number of peripheral blood stem cells when given a mobilizing regimen of G-CSF: implications for the heavily pretreated patient
    Patrick Stiff
    BMT Program, Loyola University Stritch School of Medicine, Maywood, Illinois, USA
    Biol Blood Marrow Transplant 15:249-56. 2009
  8. doi request reprint Clinical and ultrasonic evaluation of spleen size during peripheral blood progenitor cell mobilization by filgrastim: results of an open-label trial in normal donors
    Patrick J Stiff
    Division of Hematology Oncology, Loyola University Medical Center, Maywood, IL 60153, USA
    Biol Blood Marrow Transplant 15:827-34. 2009
  9. pmc High-dose chemotherapy with blood or bone marrow transplants for rhabdomyosarcoma
    Patrick J Stiff
    Loyola University Medical Center, 2160 South 1st Avenue, Maywood, IL 60153, USA
    Biol Blood Marrow Transplant 16:525-32. 2010
  10. doi request reprint Transplanted CD34(+) cell dose is associated with long-term platelet count recovery following autologous peripheral blood stem cell transplant in patients with non-Hodgkin lymphoma or multiple myeloma
    Patrick J Stiff
    Loyola University, Chicago, IL 60153, USA
    Biol Blood Marrow Transplant 17:1146-53. 2011

Research Grants

  1. CARDINAL BERNARDIN CANCER CENTER, LOYOLA UNIVERSITY
    Patrick Stiff; Fiscal Year: 2002
  2. SOUTHWEST ONCOLOGY GROUP
    Patrick Stiff; Fiscal Year: 2007
  3. SOUTHWEST ONCOLOGY GROUP
    Patrick Stiff; Fiscal Year: 2007

Detail Information

Publications37

  1. doi request reprint Prevention of nausea and vomiting associated with stem cell transplant: results of a prospective, randomized trial of aprepitant used with highly emetogenic preparative regimens
    Patrick J Stiff
    Bone Marrow Transplant Program, Department of Pharmacy, University Medical Center, Maywood, Illinois, USA
    Biol Blood Marrow Transplant 19:49-55.e1. 2013
    ....
  2. ncbi request reprint Palifermin reduces patient-reported mouth and throat soreness and improves patient functioning in the hematopoietic stem-cell transplantation setting
    Patrick J Stiff
    Cardinal Bernardin Cancer Center, Maywood, IL 60153, USA
    J Clin Oncol 24:5186-93. 2006
    ....
  3. ncbi request reprint Reliability and validity of a patient self-administered daily questionnaire to assess impact of oral mucositis (OM) on pain and daily functioning in patients undergoing autologous hematopoietic stem cell transplantation (HSCT)
    P J Stiff
    Cardinal Bernardin Cancer Center, Loyola University, Maywood, IL 60153, USA
    Bone Marrow Transplant 37:393-401. 2006
    ..Changes in MTS scores were similar, but patients detected changes 1-3 days earlier than clinicians. In conclusion, the OMDQ is a feasible, reliable, valid, and responsive patient-reported measure of OM severity...
  4. ncbi request reprint Patients' understanding of disease status and treatment plan at initial hematopoietic stem cell transplantation consultation
    P J Stiff
    Department of Medicine, Loyola University Medical Center, Maywood, IL, USA
    Bone Marrow Transplant 37:479-84. 2006
    ....
  5. ncbi request reprint Autologous hematopoietic stem cell transplants that utilize total body irradiation can safely be carried out entirely on an outpatient basis
    P Stiff
    Bone Marrow Transplant Program, Loyola University Medical Center, Maywood, IL 60153, USA
    Bone Marrow Transplant 38:757-64. 2006
    ..Patients undergoing severely mucotoxic regimens can be safely transplanted in an outpatient setting with a significant cost saving, with no increase in morbidity or mortality...
  6. ncbi request reprint Mucositis: continuing progress for a continuing need
    Patrick J Stiff
    Division of Hematology Oncology, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA
    J Support Oncol 5:47-62. 2007
  7. doi request reprint Treatment with plerixafor in non-Hodgkin's lymphoma and multiple myeloma patients to increase the number of peripheral blood stem cells when given a mobilizing regimen of G-CSF: implications for the heavily pretreated patient
    Patrick Stiff
    BMT Program, Loyola University Stritch School of Medicine, Maywood, Illinois, USA
    Biol Blood Marrow Transplant 15:249-56. 2009
    ..Plerixafor and G-CSF increased circulating CD34 cells/microL and led to the adequate collection of stem cells for autotransplant in 96% of the patients. This combination may have particular value in heavily pretreated patients...
  8. doi request reprint Clinical and ultrasonic evaluation of spleen size during peripheral blood progenitor cell mobilization by filgrastim: results of an open-label trial in normal donors
    Patrick J Stiff
    Division of Hematology Oncology, Loyola University Medical Center, Maywood, IL 60153, USA
    Biol Blood Marrow Transplant 15:827-34. 2009
    ..We conclude that the increase in splenic volume during PBPC mobilization in donors was transient, and that filgrastim was well tolerated in this study. This trial was registered at www.ClinicalTrials.gov as NCT00115128...
  9. pmc High-dose chemotherapy with blood or bone marrow transplants for rhabdomyosarcoma
    Patrick J Stiff
    Loyola University Medical Center, 2160 South 1st Avenue, Maywood, IL 60153, USA
    Biol Blood Marrow Transplant 16:525-32. 2010
    ..Even when performed after relapse for alveolar/undifferentiated histologies, long-term survivals were seen seemingly better than results with conventional therapies...
  10. doi request reprint Transplanted CD34(+) cell dose is associated with long-term platelet count recovery following autologous peripheral blood stem cell transplant in patients with non-Hodgkin lymphoma or multiple myeloma
    Patrick J Stiff
    Loyola University, Chicago, IL 60153, USA
    Biol Blood Marrow Transplant 17:1146-53. 2011
    ..006). Our analyses confirm previous findings that transplanted CD34(+) cell dose may be associated with better long-term platelet recovery after ASCT...
  11. ncbi request reprint Randomized Phase II trial of two high-dose chemotherapy regimens with stem cell transplantation for the treatment of advanced ovarian cancer in first remission or chemosensitive relapse: a Southwest Oncology Group study
    Patrick J Stiff
    Loyola University Stritch School of Medicine, Maywood, IL 60153, USA
    Gynecol Oncol 94:98-106. 2004
    ....
  12. ncbi request reprint Replicative response, immunophenotype, and functional activity of monocyte-derived versus CD34(+)-derived dendritic cells following exposure to various expansion and maturational stimuli
    B Chen
    Department of Medicine, Cardinal Bernardin Cancer Center, Maywood, Illinois, 60153-5385, USA
    Clin Immunol 98:280-92. 2001
    ..We conclude that both cell lineages produce potent mature DC, permitting exploration of the optimal clinical strategy to trigger anti-tumor immune responses in patients with malignancies...
  13. ncbi request reprint Double-blind comparative trial of oral ondansetron versus oral granisetron versus IV ondansetron in the prevention of nausea and vomiting associated with highly emetogenic preparative regimens prior to stem cell transplantation
    M P Fox-Geiman
    Department of Pharmacy, Nursing and Medicine, and the Bone Marrow Transplant Program, Loyola University Medical Center, Maywood, Illinois 60154, USA
    Biol Blood Marrow Transplant 7:596-603. 2001
    ..A cost analysis revealed significant differences among all arms (P = .0001, all comparisons). All 3 regimens had similar efficacy in this BMT population; oral ondansetron was the most cost-effective...
  14. ncbi request reprint Successful autologous peripheral blood stem cell transplantation in transformed follicular lymphoma previously treated with radioimmunotherapy (iodine (131)I tositumomab)
    J Cooney
    University of Loyola Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA
    Bone Marrow Transplant 29:523-5. 2002
    ..He remains in complete remission with normal blood counts 25 months post autograft...
  15. ncbi request reprint A phase II trial evaluating the safety and effectiveness of the AastromReplicell system for augmentation of low-dose blood stem cell transplantation
    A L Pecora
    Department of Medicine, Hackensack University Medical Center, Hackensack, NJ, USA
    Bone Marrow Transplant 28:295-303. 2001
    ..551, P = 0.004). Our results indicate that ex vivo expanded bone marrow is capable of facilitating engraftment when combined with low doses of mobilized blood derived CD34(+) cells...
  16. doi request reprint Feasibility of conditioning with thymoglobulin and reduced intensity TBI to reduce acute GVHD in recipients of allogeneic SCT
    A Toor
    Bone Marrow Transplant Program, Department of Internal Medicine, Stritch School of Medicine, Loyola University Medical Center, Maywood, IL, USA
    Bone Marrow Transplant 42:723-31. 2008
    ..We conclude that 10 mg/kg ATG and TBI allows engraftment with a low risk of acute GVHD; however, further dose optimization of ATG is required to achieve a balance between GVHD and disease relapse...
  17. ncbi request reprint Mucositis associated with stem cell transplantation: current status and innovative approaches to management
    P Stiff
    Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA
    Bone Marrow Transplant 27:S3-S11. 2001
    ....
  18. ncbi request reprint A phase I/II study of galiximab (an anti-CD80 monoclonal antibody) in combination with rituximab for relapsed or refractory, follicular lymphoma
    J P Leonard
    Division of Hematology Oncology, Weill Medical College of Cornell University and NewYork Presbyterian Hospital, New York, NY 10021, USA
    Ann Oncol 18:1216-23. 2007
    ..A phase I/II study was conducted to evaluate galiximab in combination with a standard course of rituximab. Safety, pharmacokinetics, and efficacy were evaluated...
  19. ncbi request reprint Posaconazole salvage therapy allows successful allogeneic hematopoietic stem cell transplantation in patients with refractory invasive mold infections
    K Mullane
    Section of Infectious Diseases, Loyola University Medical Center, Maywood, Illinois, USA
    Transpl Infect Dis 9:89-96. 2007
    ..The median duration of posaconazole treatment before HSCT was 5 months (range: 1.5-6 months). Posaconazole salvage therapy allowed successful allogeneic HSCT in 3 patients with refractory invasive mold infections...
  20. ncbi request reprint Second allografts for relapsed hematologic malignancies: feasibility of using a different donor
    J E Duus
    Bone Marrow Transplant Program, Department of Internal Medicine, Loyola University Medical Center, Stritch School of Medicine, Maywood, IL 60153, USA
    Bone Marrow Transplant 35:261-4. 2005
    ..There were no cases of transplant-related mortality. We conclude that a second allogeneic HSCT using a different donor is a viable option for selected patients relapsing after an allograft if the original donor is not available...
  21. ncbi request reprint Analysis of remobilization success in patients undergoing autologous stem cell transplants who fail an initial mobilization: risk factors, cytokine use and cost
    S Boeve
    BMT Program, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA
    Bone Marrow Transplant 33:997-1003. 2004
    ..001). Most patients failing an initial mobilization benefit from a cytokine only remobilization. Lower cost G-CSF+GM-CSF is as effective as high-dose G-CSF...
  22. ncbi request reprint Retrospective utility of bronchoscopy after hematopoietic stem cell transplant
    C C Hofmeister
    Division of Hematology, Department of Medicine, The Ohio State University, Arthur G James Cancer Hospital, B321 Starling Loving Hall, 320 West 10th Avenue, Columbus, OH 43210, USA
    Bone Marrow Transplant 38:693-8. 2006
    ....
  23. ncbi request reprint BEAM allogeneic transplantation for patients with Hodgkin's disease who relapse after autologous transplantation is safe and effective
    Julian P Cooney
    BMT Program, Loyola University Medical Center, Maywood, Illinois, USA
    Biol Blood Marrow Transplant 9:177-82. 2003
    ..A graft versus lymphoma effect appears to be a significant contributing factor in responding patients...
  24. ncbi request reprint Mucosal protection by cytokines
    Craig C Hofmeister
    Cardinal Bernardin Cancer Center, Loyola University Medical Center, Maywood, IL 60153, USA
    Curr Hematol Rep 4:446-53. 2005
    ..Several other potentially effective agents are in clinical trials. After 40 years of painful mucositis, relief for patients finally is in sight...
  25. pmc Total body irradiation, etoposide, cyclophosphamide, and autologous peripheral blood stem-cell transplantation followed by randomization to therapy with interleukin-2 versus observation for patients with non-Hodgkin lymphoma: results of a phase 3 randomiz
    John A Thompson
    Puget Sound Oncology Consortium, Seattle, WA, USA
    Blood 111:4048-54. 2008
    ..Posttransplantation IL-2 given at this dose and schedule of administration had no significant effect on PFS or OS. This study is registered at www.clinicaltrials.gov as NCT00002649...
  26. ncbi request reprint Economic impact of palifermin on the costs of hospitalization for autologous hematopoietic stem-cell transplant: analysis of phase 3 trial results
    Linda S Elting
    Health Services Research, Department of Biostatistics, University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Biol Blood Marrow Transplant 13:806-13. 2007
    ..In addition to its previously demonstrated clinical benefit, palifermin prophylaxis offers a favorable economic profile among patients with hematologic malignancies who receive total body irradiation and autologous stem cell support...
  27. ncbi request reprint Utility of single versus tandem autotransplants for advanced testes/germ cell cancer: a center for international blood and marrow transplant research (CIBMTR) analysis
    Hillard M Lazarus
    University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
    Biol Blood Marrow Transplant 13:778-89. 2007
    ..Patient selection bias for either transplant approach, however, may affect the results of this observational study; a randomized trial is needed to determine which approach, if either, is better...
  28. ncbi request reprint Favourable results with a single autologous stem cell transplant following conditioning with busulphan and cyclophosphamide in patients with multiple myeloma
    Amir A Toor
    Bone Marrow Transplant Program, Cardinal Bernardin Cancer Center, Loyola University Medical Center, Maywood, IL 60153, USA
    Br J Haematol 124:769-76. 2004
    ..Busulphan and cyclophosphamide is an effective and well-tolerated preparative regimen for ASCT that can be given to MM patients in the outpatient setting...
  29. ncbi request reprint The value of augmented preparative regimens combined with an autologous bone marrow transplant for the management of relapsed or refractory Hodgkin disease: a Southwest Oncology Group phase II trial
    Patrick J Stiff
    Loyola University Stritch School of Medicine, Maywood, Illinois, USA
    Biol Blood Marrow Transplant 9:529-39. 2003
    ..A poor-prognosis group was identified that should be treated with novel therapies...
  30. ncbi request reprint Current treatment results of allogeneic bone marrow transplantation for acute myeloid and lymphoid leukemia
    Tulio E Rodriguez
    Division of Hematology Oncology, Department of Medicine, Loyola University Stritch School of Medicine, Loyola University Chicago, 2160 South First Avenue, Maywood, IL 60153, USA
    Curr Hematol Rep 2:295-301. 2003
    ....
  31. ncbi request reprint Clinical utility of autopsy after hematopoietic stem cell transplantation
    Craig C Hofmeister
    The Ohio State University, Columbus, Ohio 43210 1240, USA
    Biol Blood Marrow Transplant 13:26-30. 2007
    ..Improvements in noninvasive tests for relapse or occult infections may further erode the role of autopsies in discovering missed diagnoses...
  32. ncbi request reprint Autologous stem cell transplantation for small cell lung cancer
    J Douglas Rizzo
    Statistical Center, Health Policy Institute, Medical College of Wisconsin, Milwaukee 53226, USA
    Biol Blood Marrow Transplant 8:273-80. 2002
    ..Transplantation for patients with extensive disease does not appear to produce substantial benefit...
  33. ncbi request reprint Post-transplant air-leak syndrome
    Tawee Tanvetyanon
    Division of Hematology Oncology, Department of Medicine, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA
    Br J Haematol 126:758. 2004
  34. ncbi request reprint Second allogeneic transplantation using a reduced-intensity preparative regimen for relapsed myelofibrosis
    Tawee Tanvetyanon
    Am J Hematol 77:204-5. 2004
  35. ncbi request reprint Oral mucositis therapy comes of age
    Patrick J Stiff
    J Support Oncol 3:73-5. 2005
  36. ncbi request reprint The challenges of oral mucositis and its therapy
    Patrick J Stiff
    J Support Oncol 2:70-2. 2004
  37. ncbi request reprint Alefacept in corticosteroid refractory graft versus host disease: early results indicate promising activity
    Amir A Toor
    Bone Marrow Transplantation Program, Stritch School of Medicine, Loyola University Medical Center, Maywood, IL, USA
    J Dermatolog Treat 18:13-8. 2007
    ..The pathological and immunohistochemical findings of GVHD also improved, validating our clinical impression. These preliminary findings indicate that alefacept may have beneficial activity in GVHD warranting further study...

Research Grants5

  1. CARDINAL BERNARDIN CANCER CENTER, LOYOLA UNIVERSITY
    Patrick Stiff; Fiscal Year: 2002
    ..At the completion of this grant, the Cardinal Bernardin Cancer Center plans to be positioned to successfully apply for a P-30 Cancer Center Support Grant. ..
  2. SOUTHWEST ONCOLOGY GROUP
    Patrick Stiff; Fiscal Year: 2007
    ..In addition, Loyola has three affiliate institutions participating in SWPG studies: Good Samaritan Hospital, Downer's Grove IL; St. Mary's Provena Medical Center, Kankakee IL; and Quad Cities CGOP, Davenport IA. ..
  3. SOUTHWEST ONCOLOGY GROUP
    Patrick Stiff; Fiscal Year: 2007
    ..In addition, Loyola has three affiliate institutions participating in SWPG studies: Good Samaritan Hospital, Downer's Grove IL; St. Mary's Provena Medical Center, Kankakee IL; and Quad Cities CGOP, Davenport IA. ..