M M Picken

Summary

Affiliation: Loyola University Medical Center
Country: USA

Publications

  1. doi request reprint Non-light-chain immunoglobulin amyloidosis: time to expand or refine the spectrum to include light+heavy chain amyloidosis?
    Maria M Picken
    Department of Pathology, Loyola University Medical Center, Building 110, Room 2242, 2160 S First Avenue, Maywood, Illinois 60153, USA
    Kidney Int 83:353-6. 2013
  2. ncbi request reprint Mixed epithelial and stromal tumor of the kidney: preliminary immunohistochemical and electron microscopic studies of the epithelial component
    M M Picken
    Loyola University Medical Center, Chicago, 60153, USA
    Ultrastruct Pathol 29:283-6. 2005
  3. ncbi request reprint Immunoglobulin light and heavy chain amyloidosis AL/AH: renal pathology and differential diagnosis
    Maria M Picken
    Loyola University Chicago, Loyola University Medical Center, Department of Pathology, Maywood, IL 60153, USA
    Contrib Nephrol 153:135-55. 2007
  4. ncbi request reprint New insights into systemic amyloidosis: the importance of diagnosis of specific type
    Maria M Picken
    Loyola University Medical Center, Maywood, Illinois 60153, USA
    Curr Opin Nephrol Hypertens 16:196-203. 2007
  5. doi request reprint Analysis of chromosome 1p abnormalities in renal oncocytomas by loss of heterozygosity studies: correlation with conventional cytogenetics and fluorescence in situ hybridization
    Maria M Picken
    Department of Pathology, Loyola University Medical Center, Maywood, IL 60153, USA
    Am J Clin Pathol 129:377-82. 2008
  6. ncbi request reprint Metanephric adenosarcoma in a young adult: morphologic, immunophenotypic, ultrastructural, and fluorescence in situ hybridization analyses: a case report and review of the literature
    M M Picken
    Department of Pathology, Loyola University Medical Center, Chicago, Illinois 60153, USA
    Am J Surg Pathol 25:1451-7. 2001
  7. doi request reprint Nephrotic syndrome due to an amyloidogenic mutation in fibrinogen A alpha chain
    Maria M Picken
    Department of Pathology, Loyola University Medical Center, Maywood, IL 60153, USA
    J Am Soc Nephrol 20:1681-5. 2009
  8. ncbi request reprint The changing concepts of amyloid
    M M Picken
    Department of Pathology, Loyola University Medical Center, Maywood, Ill 60153, USA
    Arch Pathol Lab Med 125:38-43. 2001
  9. doi request reprint The role of mesangial homeostasis in glomerular injury progression: hope for mesangial sclerosis reversal
    Maria M Picken
    Department of Pathology, Loyola University, Chicago, Illinois, USA
    Kidney Int 75:574-6. 2009
  10. doi request reprint Amyloidosis-where are we now and where are we heading?
    Maria M Picken
    Department of Pathology, Loyola University Medical Center, Maywood, Illinois 60153, USA
    Arch Pathol Lab Med 134:545-51. 2010

Collaborators

Detail Information

Publications40

  1. doi request reprint Non-light-chain immunoglobulin amyloidosis: time to expand or refine the spectrum to include light+heavy chain amyloidosis?
    Maria M Picken
    Department of Pathology, Loyola University Medical Center, Building 110, Room 2242, 2160 S First Avenue, Maywood, Illinois 60153, USA
    Kidney Int 83:353-6. 2013
    ....
  2. ncbi request reprint Mixed epithelial and stromal tumor of the kidney: preliminary immunohistochemical and electron microscopic studies of the epithelial component
    M M Picken
    Loyola University Medical Center, Chicago, 60153, USA
    Ultrastruct Pathol 29:283-6. 2005
    ..Additional studies are needed to address this issue and electron microscopy should play a significant role in this process...
  3. ncbi request reprint Immunoglobulin light and heavy chain amyloidosis AL/AH: renal pathology and differential diagnosis
    Maria M Picken
    Loyola University Chicago, Loyola University Medical Center, Department of Pathology, Maywood, IL 60153, USA
    Contrib Nephrol 153:135-55. 2007
    ..Whenever possible, the most recent references, considered as being particularly useful to clinicians and pathologists serving patients with renal amyloidosis, have been selected...
  4. ncbi request reprint New insights into systemic amyloidosis: the importance of diagnosis of specific type
    Maria M Picken
    Loyola University Medical Center, Maywood, Illinois 60153, USA
    Curr Opin Nephrol Hypertens 16:196-203. 2007
    ..This review aims to summarize recent developments in the area of systemic amyloidoses with emphasis on pathologic diagnosis...
  5. doi request reprint Analysis of chromosome 1p abnormalities in renal oncocytomas by loss of heterozygosity studies: correlation with conventional cytogenetics and fluorescence in situ hybridization
    Maria M Picken
    Department of Pathology, Loyola University Medical Center, Maywood, IL 60153, USA
    Am J Clin Pathol 129:377-82. 2008
    ..Determining whether such abnormalities are unique to renal oncocytomas or are also present in other tumors requires further studies...
  6. ncbi request reprint Metanephric adenosarcoma in a young adult: morphologic, immunophenotypic, ultrastructural, and fluorescence in situ hybridization analyses: a case report and review of the literature
    M M Picken
    Department of Pathology, Loyola University Medical Center, Chicago, Illinois 60153, USA
    Am J Surg Pathol 25:1451-7. 2001
    ..We conclude that the spectrum of metanephric neoplasia should be expanded to include malignant stromal variants, and we propose the term "metanephric adenosarcoma" for the present case...
  7. doi request reprint Nephrotic syndrome due to an amyloidogenic mutation in fibrinogen A alpha chain
    Maria M Picken
    Department of Pathology, Loyola University Medical Center, Maywood, IL 60153, USA
    J Am Soc Nephrol 20:1681-5. 2009
    ..Negative or inconclusive results must be investigated further by a reference laboratory with the capability of applying more sophisticated methods...
  8. ncbi request reprint The changing concepts of amyloid
    M M Picken
    Department of Pathology, Loyola University Medical Center, Maywood, Ill 60153, USA
    Arch Pathol Lab Med 125:38-43. 2001
    ..This article seeks to provide a synopsis of the present state of our knowledge with regard to these disorders, including current terminology, classification, major clinical syndromes, and diagnosis...
  9. doi request reprint The role of mesangial homeostasis in glomerular injury progression: hope for mesangial sclerosis reversal
    Maria M Picken
    Department of Pathology, Loyola University, Chicago, Illinois, USA
    Kidney Int 75:574-6. 2009
    ..Keeling and Herrera have demonstrated the development of such nodules in vitro using a human mesangial cell culture model. Lessons learned from this model might be applicable to other types of glomerular sclerosis...
  10. doi request reprint Amyloidosis-where are we now and where are we heading?
    Maria M Picken
    Department of Pathology, Loyola University Medical Center, Maywood, Illinois 60153, USA
    Arch Pathol Lab Med 134:545-51. 2010
    ..With recent advances in the treatment of systemic amyloidoses the importance of an early diagnosis of amyloid, and a correct diagnosis of its type, has been realized...
  11. ncbi request reprint The evolving concept of renal neoplasia: impact of emerging molecular and electron microscopic studies
    Maria M Picken
    Department of Pathology, Loyola University Medical Center, Chicago, Illinois 60153, USA
    Ultrastruct Pathol 29:277-82. 2005
    ..The author concludes that although the routine application of electron microscopy to kidney tumor diagnosis may not be practical, systematic ultrastructural studies of these tumors may aid in the definition of new entities...
  12. ncbi request reprint Immunoglobulin light chains and the kidney: an overview
    M M Picken
    Department of Pathology, Loyola University Medical Center, Maywood, Illinois 60153
    Ultrastruct Pathol 18:105-12. 1994
    ..The main diagnostic features, differential diagnosis, and pathogenesis are briefly reviewed...
  13. ncbi request reprint beta 2-Microglobulin amyloidosis: illustrative cases
    M M Picken
    Loyola University Medical Center, Maywood, Illinois 60153
    Ultrastruct Pathol 18:133-6. 1994
    ..The distribution of amyloid deposits in such patients as well as tissue diagnosis, immunohistochemistry, and electron microscopic features are briefly discussed...
  14. ncbi request reprint Metastatic renal cell carcinoma
    Robert C Flanigan
    Department of Urology, Loyola University Medical Center, Cardinal Bernardin Cancer Center and Hines VA Hospital, Maywood, IL 60153, USA
    Curr Treat Options Oncol 4:385-90. 2003
    ....
  15. ncbi request reprint Electroanatomic mapping of the right ventricle in a patient with a giant epsilon wave, ventricular tachycardia, and cardiac sarcoidosis
    Peter A Santucci
    Loyola Cardiovascular Institute, Loyola University Medical Center, Maywood, Illinois 60153, USA
    J Cardiovasc Electrophysiol 15:1091-4. 2004
    ..Electroanatomic mapping was used to characterize the right ventricular substrate abnormalities and to decipher the specific activation abnormalities responsible for the ECG findings...
  16. doi request reprint The importance of histology and cytogenetics in decision making for renal cell carcinoma
    Julia G Garcia
    Department of Urology, Loyola University Medical Center, 2160 South First Avenue, Blg 54, Maywood, IL 60153, USA
    World J Urol 26:155-60. 2008
    ..The benefit of these therapies hinges on the critical diagnosis attained via the role of histology and cytogenetics...
  17. ncbi request reprint Pathologic quiz case: renal mass in an otherwise healthy man. Epithelioid angiomyolipoma
    Tara C Rubinas
    Department of Pathology, Loyola University Medical Center, Maywood, IL 60153, USA
    Arch Pathol Lab Med 128:e19-20. 2004
  18. ncbi request reprint Passive seeding in metanephric adenoma: a review of pseudometastatic lesions in perinephric lymph nodes
    Gladell P Paner
    Department of Pathology, Loyola University Medical Center, Maywood, IL 60153, USA
    Arch Pathol Lab Med 129:1317-21. 2005
    ..We conclude that this phenomenon is understudied and underrecognized and can easily be mistaken for metastasis...
  19. ncbi request reprint High incidence of chromosome 1 abnormalities in a series of 27 renal oncocytomas: cytogenetic and fluorescence in situ hybridization studies
    Gladell P Paner
    Department of Pathology, Loyola University Medical Center, Maywood, Ill 60153, USA
    Arch Pathol Lab Med 131:81-5. 2007
    ..It has recently been shown by cytogenetics that there is a high incidence of chromosome 1 abnormalities in renal oncocytomas...
  20. doi request reprint Chromosome 1 analysis in chromophobe renal cell carcinomas with tissue microarray (TMA)-facilitated fluorescence in situ hybridization (FISH) demonstrates loss of 1p/1 which is also present in renal oncocytomas
    Paul N Meyer
    Loyola University Medical Center, Maywood, IL 60153, USA
    Diagn Mol Pathol 17:141-4. 2008
    ..Whether abnormalities of chromosome 1 are associated with RO tumorigenesis or its progression to carcinoma requires further studies...
  21. doi request reprint Claudin-7 and claudin-8: immunohistochemical markers for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma
    Adeboye O Osunkoya
    Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Hum Pathol 40:206-10. 2009
    ..It may be necessary to identify additional biomarkers to include with claudin-7 and claudin-8 in a larger immunohistochemical panel to improve diagnostic sensitivity and specificity...
  22. ncbi request reprint Transjugular renal biopsy in patients with liver disease
    R Sam
    Departments of Medicine, Radiology, and Pathology, Loyola University Chicago, Stritch School of Medicine, Maywood, IL, USA
    Am J Kidney Dis 37:1144-51. 2001
    ....
  23. ncbi request reprint Glomerulopathic light chain-mesangial cell interactions modulate in vitro extracellular matrix remodeling and reproduce mesangiopathic findings documented in vivo
    G A Herrera
    Department of Pathology, Louisiana State University Medical Center, Shreveport 71130, USA
    Ultrastruct Pathol 23:107-26. 1999
    ..Using this in vitro model, it is then possible to delineate the LC interactions with putative receptors at the mesangial cell surface that regulate mesangial cell pathobiologic responses and mesangial matrix homeostasis...
  24. ncbi request reprint Pneumothorax and pulmonary cyst in a 2-year-old child. Pleuropulmonary blastoma
    Tara C Rubinas
    Department of Pathology, Loyola University Medical Center, Maywood, IL, USA
    Arch Pathol Lab Med 130:e47-9. 2006
  25. ncbi request reprint Reactive granulomatous lesion in the pterygomandibular fossa mimicking a temporomandibular disorder
    Andres F Herréra
    Loyola University Medical Center, Maywood, IL 60302, USA
    J Oral Maxillofac Surg 60:1203-6. 2002
  26. ncbi request reprint Renal tumor with overlapping distal nephron morphology and karyotype
    Valerie Lindgren
    Department of Pathology, University of Illinois at Chicago, Chicago, Ill, USA
    Arch Pathol Lab Med 128:1274-8. 2004
    ....
  27. ncbi request reprint Renal neoplasms in younger adults: analysis of 112 tumors from a single institution according to the new 2004 World Health Organization classification and 2002 American Joint Committee on Cancer Staging System
    Ying Cao
    Department of Pathology, Loyola University Chicago Medical Center, Maywood, Ill 60153, USA
    Arch Pathol Lab Med 129:487-91. 2005
    ..Recent modification of the World Health Organization histologic classification and the American Joint Committee on Cancer staging system of adult renal tumors further highlighted the need for case analysis in this age group...
  28. ncbi request reprint Expanding the pathologic spectrum of immunoglobulin light chain proximal tubulopathy
    Umesh Kapur
    Department of Pathology, Loyola University Medical Center, Maywood, Ill, USA
    Arch Pathol Lab Med 131:1368-72. 2007
    ..In plasma cell dyscrasias, involvement of the distal tubules is frequent and well characterized. In contrast, proximal tubules have only rarely been reported to show diagnostic pathology such as intracytoplasmic crystals...
  29. ncbi request reprint Xp11.2 translocation renal cell carcinoma with very aggressive course in five adults
    Paul N Meyer
    Department of Pathology, Loyola University Medical Center, Maywood, IL 60153, USA
    Am J Clin Pathol 128:70-9. 2007
    ..Various treatments met with minimal success. Unlike pediatric patients, the adult patients followed a rapidly terminal course, with a mean survival of 18 months after diagnosis (range, 10-24 months)...
  30. doi request reprint Prospective study of cardiac sarcoid mimicking arrhythmogenic right ventricular dysplasia
    Smit C Vasaiwala
    Cardiovascular Institute, Loyola University Medical Center, Maywood, Illinois 60153, USA
    J Cardiovasc Electrophysiol 20:473-6. 2009
    ....
  31. ncbi request reprint Metastatic juxtaglomerular cell tumor in a 52-year-old man
    Xiuzhen Duan
    Department of Pathology, Loyola University Medical Center, 2160 S First Avenue, Maywood, IL 60153, USA
    Am J Surg Pathol 28:1098-102. 2004
    ..In consideration of the characteristic morphologic features, immunohistochemistry, and the presence of rhomboid crystals of proto-renin, the diagnosis was modified to malignant juxtaglomerular cell tumor...
  32. ncbi request reprint Cytogenetic analysis of a series of 13 renal oncocytomas
    Valerie Lindgren
    Department of Pathology, University of Illinois at Chicago, 60612, USA
    J Urol 171:602-4. 2004
    ..Additional abnormalities may occur with transformation to chromophobe renal cell carcinoma, although exactly which one is unclear. We expanded the oncocytoma data base to shed light on changes that characterize transformation...
  33. ncbi request reprint Simultaneous transjugular renal biopsy and hemodialysis catheter placement in patients with ARF
    Mohammed S Ahmed
    Department of Medicine, Loyola University Stritch School of Medicine, Maywood, IL, USA
    Am J Kidney Dis 44:429-36. 2004
    ..We sought to evaluate transjugular renal biopsy in patients with acute renal failure (ARF) or ARF in the presence of chronic renal insufficiency (CRI) who required venous catheter placement for hemodialysis (HD)...
  34. ncbi request reprint Treatment of idiopathic membranous nephropathy with the herb Astragalus membranaceus
    Mohammed S Ahmed
    Department of Medicine, Loyola University Medical Center, Maywood, IL 60153, USA
    Am J Kidney Dis 50:1028-32. 2007
    ..The clinical course of this patient suggests that Astragalus may have beneficial effects in patients with idiopathic membranous nephropathy...
  35. ncbi request reprint Mixed epithelial and stromal tumor of the kidney and cystic nephroma share overlapping features: reappraisal of 15 lesions
    Tatjana Antic
    Department of Pathology, Loyola University Medical Center, Maywood, IL 60153, USA
    Arch Pathol Lab Med 130:80-5. 2006
    ..The histogenesis of both lesions is unclear...
  36. ncbi request reprint Blood pressure lability and glomerulosclerosis after normotensive 5/6 renal mass reduction in the rat
    Karen A Griffin
    Department of Internal Medicine, Loyola University Medical Center and Hines VA Hospital, Maywood, Illinois 60153, USA
    Kidney Int 65:209-18. 2004
    ..However, the pathogenesis of the more slowly developing glomerulosclerosis that is seen even in the absence of overt hypertension, both in renal mass reduction models and in humans with chronic renal disease, remains controversial...
  37. ncbi request reprint Albuminuria in acute tubular necrosis
    Bradford Lee West
    Department of Medicine, Loyola University Medical Center, 2160 S 1st Avenue, Maywood, IL 60153, USA
    Nephrol Dial Transplant 21:2953-6. 2006
  38. ncbi request reprint Claudin-7 immunohistochemistry in renal tumors: a candidate marker for chromophobe renal cell carcinoma identified by gene expression profiling
    Christopher D Hornsby
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
    Arch Pathol Lab Med 131:1541-6. 2007
    ..Immunohistochemistry is useful for distinguishing chromophobe RCC from other subtypes of renal carcinoma, but no expression marker reliably separates chromophobe RCC from oncocytoma...
  39. ncbi request reprint Pathology of plasma cell dyscrasia: how much can we learn from autopsy studies?
    Maria M Picken
    Arch Pathol Lab Med 128:1082-4. 2004
  40. ncbi request reprint The burden of "sticky" amyloid: typing challenges
    Maria M Picken
    Arch Pathol Lab Med 131:850-1. 2007