Amy H Luke

Summary

Affiliation: Loyola University Medical Center
Country: USA

Publications

  1. ncbi request reprint Activity energy expenditure and adiposity among black adults in Nigeria and the United States
    Amy Luke
    Department of Preventive Medicine and Epidemiology, Loyola University School of Medicine, Maywood, IL 60153, USA
    Am J Clin Nutr 75:1045-50. 2002
  2. pmc Prediction of fat-free mass using bioelectrical impedance analysis in young adults from five populations of African origin
    A Luke
    Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA
    Eur J Clin Nutr 67:956-60. 2013
  3. pmc Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk
    Amy Luke
    Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA
    BMC Public Health 11:927. 2011
  4. pmc Rapid increases in obesity in Jamaica, compared to Nigeria and the United States
    Ramon A Durazo-Arvizu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical School, Maywood, IL, USA
    BMC Public Health 8:133. 2008
  5. pmc An international comparative study of blood pressure in populations of European vs. African descent
    Richard S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, IL, USA
    BMC Med 3:2. 2005
  6. ncbi request reprint Ethnicity, energy expenditure and obesity: are the observed black/white differences meaningful?
    Amy Luke
    Department of Preventive Medicine and Epidemiology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 60153, USA
    Curr Opin Endocrinol Diabetes Obes 14:370-3. 2007
  7. ncbi request reprint Relationship between blood pressure and physical activity assessed with stable isotopes
    A Luke
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    J Hum Hypertens 19:127-32. 2005
  8. ncbi request reprint Activity, adiposity and weight change in Jamaican adults
    A Luke
    Department of Preventitive Medicine and Epidemiology, Loyola University Medical Centre, Maywood, IL 60153, USA
    West Indian Med J 56:398-403. 2007
  9. ncbi request reprint Association between blood pressure and resting energy expenditure independent of body size
    Amy Luke
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    Hypertension 43:555-60. 2004
  10. ncbi request reprint Linkage for BMI at 3q27 region confirmed in an African-American population
    Amy Luke
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, 2160 South First Avenue, Maywood, IL 60153, USA
    Diabetes 52:1284-7. 2003

Detail Information

Publications38

  1. ncbi request reprint Activity energy expenditure and adiposity among black adults in Nigeria and the United States
    Amy Luke
    Department of Preventive Medicine and Epidemiology, Loyola University School of Medicine, Maywood, IL 60153, USA
    Am J Clin Nutr 75:1045-50. 2002
    ..The prevalence of obesity is higher among populations in industrialized than in developing countries...
  2. pmc Prediction of fat-free mass using bioelectrical impedance analysis in young adults from five populations of African origin
    A Luke
    Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA
    Eur J Clin Nutr 67:956-60. 2013
    ..Because of significant under-representation in existing literature, we sought to develop and validate predictive equation(s) for BIA for studies in populations of African origin...
  3. pmc Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk
    Amy Luke
    Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA
    BMC Public Health 11:927. 2011
    ..However there are few empirical data to support the assertion that low levels of energy expenditure in activity is a causal factor in the current obesity epidemic are very limited...
  4. pmc Rapid increases in obesity in Jamaica, compared to Nigeria and the United States
    Ramon A Durazo-Arvizu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical School, Maywood, IL, USA
    BMC Public Health 8:133. 2008
    ..To examine the rate of change across the spectrum of low to high-income countries we compared rates of weight change in samples drawn from three countries, Nigeria, Jamaica and the United States...
  5. pmc An international comparative study of blood pressure in populations of European vs. African descent
    Richard S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, IL, USA
    BMC Med 3:2. 2005
    ..Large surveys now provide new information on this issue...
  6. ncbi request reprint Ethnicity, energy expenditure and obesity: are the observed black/white differences meaningful?
    Amy Luke
    Department of Preventive Medicine and Epidemiology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 60153, USA
    Curr Opin Endocrinol Diabetes Obes 14:370-3. 2007
    ..These findings initiated much research on race as a primary biological determinant of obesity and energy expenditure as a potential pathway. Race is a difficult construct to use in biomedical research...
  7. ncbi request reprint Relationship between blood pressure and physical activity assessed with stable isotopes
    A Luke
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    J Hum Hypertens 19:127-32. 2005
    ..In conclusion these data suggest that habitual levels of physical activity may have a generalizable relationship with BP in populations with widely different social and environmental characteristics...
  8. ncbi request reprint Activity, adiposity and weight change in Jamaican adults
    A Luke
    Department of Preventitive Medicine and Epidemiology, Loyola University Medical Centre, Maywood, IL 60153, USA
    West Indian Med J 56:398-403. 2007
    ..We sought to determine the relationship between activity energy expenditure (AEE), adiposity and weight change in an adult population undergoing rapid socio-economic transition...
  9. ncbi request reprint Association between blood pressure and resting energy expenditure independent of body size
    Amy Luke
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    Hypertension 43:555-60. 2004
    ..The interrelationship of REE with sympathetic tone, transmembrane ion exchange, or other metabolic processes that determine energy costs at rest could provide physiological explanations for this observation...
  10. ncbi request reprint Linkage for BMI at 3q27 region confirmed in an African-American population
    Amy Luke
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, 2160 South First Avenue, Maywood, IL 60153, USA
    Diabetes 52:1284-7. 2003
    ..The multiple replications of linkage evidence in the region on 3q27 strongly confirm its potential importance as a candidate region in the search for obesity-related genes...
  11. pmc Energy expenditure does not predict weight change in either Nigerian or African American women
    Amy Luke
    Department of Preventive Medicine and Epidemiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA
    Am J Clin Nutr 89:169-76. 2009
    ..The relation between variation in interindividual levels of energy expenditure and weight gain remains controversial...
  12. pmc Assessing physical activity and its relationship to cardiovascular risk factors: NHANES 2003-2006
    Amy Luke
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, 2160 S, 1st Ave Maywood, IL 60153, USA
    BMC Public Health 11:387. 2011
    ..The aims of the current study were to investigate the associations between objectively measured PA and cardiovascular disease risk factors and obesity...
  13. ncbi request reprint Positive association between resting energy expenditure and weight gain in a lean adult population
    Amy Luke
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, IL 60153, USA
    Am J Clin Nutr 83:1076-81. 2006
    ..Evidence of the importance of energy expenditure in adult weight change has been limited to studies conducted in Pima Indians, in whom resting energy expenditure (REE) was found to be inversely associated with weight gain...
  14. doi request reprint Adiposity is not equal in a multi-race/ethnic adolescent population: NHANES 1999-2004
    Lara R Dugas
    Department of Preventive Medicine and Epidemiology, Loyola University School of Medicine, Maywood, Illinois, USA
    Obesity (Silver Spring) 19:2099-101. 2011
    ..NHB adolescents had significantly lower %BF for BMI and MA had higher than NHW. Our results indicate that BMI may not be an equivalent measure of %BF in a multi-ethnic population of US adolescents...
  15. pmc Energy expenditure and adiposity in Nigerian and African-American women
    Kara E Ebersole
    Department of Preventive Medicine and Epidemiology, Loyola University School of Medicine, Maywood, Illinois, USA
    Obesity (Silver Spring) 16:2148-54. 2008
    ..We sought to assess the relative importance of resting energy expenditure (REE) and activity EE (AEE) in two populations with different rates of obesity...
  16. ncbi request reprint An association study of angiotensinogen polymorphisms with serum level and hypertension in an African-American population
    Xiaodong Wu
    Department of Preventive Medicine and Epidemiology, Loyola Stritch School of Medicine, Maywood, Illinois 60153, USA
    J Hypertens 21:1847-52. 2003
    ..To evaluate the association of angiotensinogen (AGT) gene with AGT level and hypertension based on the overall genetic variation of the AGT gene in among African-Americans...
  17. ncbi request reprint Admixture mapping for hypertension loci with genome-scan markers
    Xiaofeng Zhu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, 2160 S First Ave, Maywood, Illinois 60153, USA
    Nat Genet 37:177-81. 2005
    ..These results suggest that chromosome 6q24 and 21q21 may contain genes influencing risk of hypertension in African Americans...
  18. pmc A combined analysis of genomewide linkage scans for body mass index from the National Heart, Lung, and Blood Institute Family Blood Pressure Program
    Xiaodong Wu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    Am J Hum Genet 70:1247-56. 2002
    ....
  19. ncbi request reprint Urinary incontinence prevalence: results from the National Health and Nutrition Examination Survey
    Yashika Dooley
    Division of Female Pelvic Medicine and Reconstructive Surgery, Departments of Obstetrics and Gynecology and Urology, Loyola University Medical Center, Maywood, Illinois, USA
    J Urol 179:656-61. 2008
    ..We determined racial differences in urinary incontinence prevalence using the 2001-2004 National Health and Nutrition Examination Survey...
  20. ncbi request reprint A genome-wide scan for obesity in African-Americans
    Xiaofeng Zhu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical School, Maywood, Illinois 60153, USA
    Diabetes 51:541-4. 2002
    ..The replication of linkage evidence using different ethnic groups reinforces the potential significance of this latter candidate region...
  21. ncbi request reprint Body composition of children in south-western Nigeria: validation of bio-electrical impedance analysis
    Cinthia R Leman
    Departments of Preventive Medicine and Epidemiology, Loyola University, Maywood, IL 60153, USA
    Ann Trop Paediatr 23:61-7. 2003
    ..Body composition data are presented by gender and age group. BIA was validated for use among Nigerian children and adults and provides a potentially important tool for research...
  22. ncbi request reprint Obesity and prevalent and incident CKD: the Hypertension Detection and Follow-Up Program
    Holly Kramer
    Department of Preventive Medicine, Loyola Medical Center, Maywood, IL 60153, USA
    Am J Kidney Dis 46:587-94. 2005
    ..However, epidemiological data supporting an association between overweight and obesity and risk for CKD currently are limited...
  23. ncbi request reprint Genome scan among Nigerians linking blood pressure to chromosomes 2, 3, and 19
    Richard S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola Medical School, Maywood, Ill 60153, USA
    Hypertension 40:629-33. 2002
    ..Study designs that make it possible to confirm these results with association analysis and narrow the genomic interval are needed in order to make progress in this field...
  24. pmc Linkage disequilibrium and haplotype diversity in the genes of the renin-angiotensin system: findings from the family blood pressure program
    Xiaofeng Zhu
    Department of Preventive Medicine and Epidemiology, Loyola Stritch School of Medicine, Maywood, Illinois 60153, USA
    Genome Res 13:173-81. 2003
    ..These findings have implications for candidate-gene association studies and indicate that variation between populations of European and African origin in haplotype diversity is characteristic of most genes...
  25. pmc Association of regions on chromosomes 6 and 7 with blood pressure in Nigerian families
    Bamidele O Tayo
    Department of Preventive Medicine and Epidemiology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 60153, USA
    Circ Cardiovasc Genet 2:38-45. 2009
    ..In our earlier genome-wide linkage study for BP in this population, strong linkage evidence was noted on chromosomes 6 and 7...
  26. doi request reprint Increasing BMI and waist circumference and prevalence of obesity among adults with Type 2 diabetes: the National Health and Nutrition Examination Surveys
    Holly Kramer
    Department of Preventive Medicine and Epidemiology, Division of Nephrology and Hypertension, Loyola University Medical Center, Maywood, IL 60153, USA
    J Diabetes Complications 24:368-74. 2010
    ..The aim of this study was to examine trends in average body mass index (BMI), waist circumference, and obesity prevalence among adults with and without Type 2 diabetes...
  27. ncbi request reprint Increasing body mass index and obesity in the incident ESRD population
    Holly J Kramer
    Loyola University Medical Center, Department of Preventive Medicine, 2160 First Avenue, Maywood, IL 60153, USA
    J Am Soc Nephrol 17:1453-9. 2006
    ..As a result of the survival advantage associated with obesity and decreased likelihood for transplantation, these trends most likely will influence the total number of patients who receive dialysis in the next decade...
  28. pmc Sugary soda consumption and albuminuria: results from the National Health and Nutrition Examination Survey, 1999-2004
    David A Shoham
    Department of Preventive Medicine and Epidemiology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA
    PLoS ONE 3:e3431. 2008
    ..Sugar-sweetened soda is a primary source of fructose. We therefore hypothesized that sugary soda consumption was associated with albuminuria, a sensitive marker for kidney disease...
  29. pmc Very low levels of energy expenditure among pre-adolescent Mexican-American girls
    Lara R Dugas
    Department of Preventive Medicine and Epidemiology, Loyola University Chicago, Stritch School of Medicine, Maywood, IL 60153, USA
    Int J Pediatr Obes 3:123-6. 2008
    ..9 vs. 64.9+/-24.7 kJ x kg(-1) x d(-1); PAL, 1.40+/-0.12 vs. 1.57+/-0.18; P <0.005). Results suggest that these MA girls were expending less energy than EA children of comparable body size due to a reduced activity energy expenditure...
  30. ncbi request reprint Associations between hypertension and genes in the renin-angiotensin system
    Xiaofeng Zhu
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Ill, USA
    Hypertension 41:1027-34. 2003
    ..Thus, in this biracial population sample, we find evidence that interindividual variation in the renin-angiotensin system genes contributes to hypertension risk...
  31. ncbi request reprint A genome scan among Nigerians linking resting energy expenditure to chromosome 16
    Xiaodong Wu
    Department of Preventive Medicine and Epidemiology, Loyola Medical School, Maywood, Illinois 60153, USA
    Obes Res 12:577-81. 2004
    ..3) with a likelihood of odds of 2.96 (p = 0.08). Linkage evidence (likelihood of odds > 1) was detected on another three chromosomal regions, namely 2q12.1, 8q21.2, and 15p11.2...
  32. ncbi request reprint Haplotypes produced from rare variants in the promoter and coding regions of angiotensinogen contribute to variation in angiotensinogen levels
    Xiaofeng Zhu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    Hum Mol Genet 14:639-43. 2005
    ..Our study confirms in an additional trait that rare variants can influence the distribution of complex traits; whether these variants can be captured by common SNPs or haplotypes requires further investigation...
  33. ncbi request reprint Angiotensin-converting enzyme gene polymorphisms and obesity: an examination of three black populations
    Holly Kramer
    Loyola Medical Center, Department of Preventive Medicine, 2160 First Avenue, Maywood, IL 60153, USA
    Obes Res 13:823-8. 2005
    ..These data suggest that ACE gene polymorphisms may influence the development of weight gain...
  34. ncbi request reprint Obesity and kidney disease: a big dilemma
    Holly Kramer
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, Illinois 60153, USA
    Curr Opin Nephrol Hypertens 16:237-41. 2007
    ..Obesity is the number one preventable risk factor for chronic kidney disease. Obesity is, however, associated with improved survival in patients with end-stage renal disease (ESRD)...
  35. ncbi request reprint A genome-wide scan of loci linked to serum adiponectin in two populations of African descent
    Chindo Hicks
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, 1219 Roosevelt Road, Maywood, IL 60153, USA
    Obesity (Silver Spring) 15:1207-14. 2007
    ..The objectives were to identify quantitative trait loci linked to serum adiponectin concentration and to estimate heritability in two populations of African descent...
  36. pmc Energy expenditure in adults living in developing compared with industrialized countries: a meta-analysis of doubly labeled water studies
    Lara R Dugas
    Department of Preventive Medicine and Epidemiology, Loyola University Chicago, Maywood, IL 60153, USA
    Am J Clin Nutr 93:427-41. 2011
    ..There is an assumption that people in developing countries have a higher total energy expenditure (TEE) and physical activity level (PAL) than do people in developed nations, but few objective data for this assertion exist...
  37. ncbi request reprint Combined analysis of genomewide scans for adult height: results from the NHLBI Family Blood Pressure Program
    Xiaodong Wu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    Eur J Hum Genet 11:271-4. 2003
    ..46), which has been reported in two previous studies. Suggestive linkage (LOD>1) was found in another six regions in our combined analysis. Evidence for linkage for two of these regions (2p12, 20p11) has also been reported previously...
  38. ncbi request reprint Heritability of blood pressure in Nigerian families
    Adebowale A Adeyemo
    College of Medicine, University of Ibadan, Ibadan, Nigeria
    J Hypertens 20:859-63. 2002
    ..This study was undertaken to provide estimates of heritability for four blood pressure phenotypes: systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) and pulse pressure...

Research Grants8

  1. ACTIVITY AND OBESITY IN US BLACK & NIGERIAN WOMEN
    Amy Luke; Fiscal Year: 2004
    ..The proposed study will not use an ecologic design, since conclusions will be based relationships defined among individuals, not the comparison of group means. ..
  2. Modeling the epidemiologic transition: Energy expenditure, obesity and diabetes
    Amy Luke; Fiscal Year: 2009
    ..To date, however, measurement of physical activity has been very crude. We propose to conduct a large international study to define the impact of daily activity level on the risk of weight gain and obesity. ..
  3. Modeling the epidemiologic transition: Energy expenditure, obesity and diabetes
    Amy H Luke; Fiscal Year: 2010
    ..To date, however, measurement of physical activity has been very crude. We propose to conduct a large international study to define the impact of daily activity level on the risk of weight gain and obesity. ..