Research Topics
| F LaghiSummaryAffiliation: Loyola University Medical Center Country: USA Publications
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Publications
Auto-PEEP in respiratory failureF Laghi
Division of Pulmonary and Critical Care Medicine, Edward Hines Jr Veterans Administration Hospital, Loyola University of Chicago Stritch School of Medicine, Hines, IL 60141, USA
Minerva Anestesiol 78:201-21. 2012..Neurally adjusted ventilatory assist, a novel strategy of ventilatory assist, may improve patient-ventilator interaction in patients with auto-PEEP...
Endocrinological derangements in COPDF Laghi
Division of Pulmonary and Critical Care Medicine, Edward Hines, Jr Veterans Administration Hospital, and Loyola University of Chicago Stritch School of Medicine, Hines, IL 60141, USA
Eur Respir J 34:975-96. 2009..A sound understanding of the various disorders of endocrine function associated with COPD is prudent for every physician who practices pulmonary medicine...
Assessment of respiratory output in mechanically ventilated patientsFranco Laghi
Division of Pulmonary and Critical Care Medicine, Edward Hines Jr Veterans Administration Hospital, Hines, IL 60141, USA
Respir Care Clin N Am 11:173-99. 2005..Finally, more research is needed to define the effect of monitoring respiratory output on patient outcome and containment of costs...
Effect of imposed inflation time on respiratory frequency and hyperinflation in patients with chronic obstructive pulmonary diseaseF Laghi
Division of Pulmonary and Critical Care Medicine, Edward Hines, Jr Veterans Administration Hospital, 111N, 5th Avenue and Roosevelt Road, Hines, IL 60141, USA
Am J Respir Crit Care Med 163:1365-70. 2001..01). In conclusion, strategies to reduce TI,vent in patients with COPD caused tachypnea, yet prolonged the time for exhalation with consequent decrease in PEEP(i)...
Hypogonadism in men with chronic obstructive pulmonary disease: prevalence and quality of lifeFranco Laghi
Division of Pulmonary and Critical Care Medicine, Edward Hines Jr VA Hospital, 111N 5th Avenue and Roosevelt Road, Hines, IL 60141, USA
Am J Respir Crit Care Med 171:728-33. 2005..In conclusion, hypogonadism, although common among men older than 54 years with COPD, does not worsen the severity of respiratory symptoms or quality of life...
Respiratory and skeletal muscles in hypogonadal men with chronic obstructive pulmonary diseaseFranco Laghi
Division of Pulmonary and Critical Care Medicine, Edward Hines Jr VA Hospital, 111N 5th Avenue and Roosevelt Road, Hines, IL 60141, USA
Am J Respir Crit Care Med 171:598-605. 2005..In conclusion, hypogonadism does not decrease respiratory or limb muscle performance and exercise capacity in men with moderate-to-severe COPD who, for the most part, are not underweight...
Effect of lung volume reduction surgery on diaphragmatic neuromechanical coupling at 2 yearsFranco Laghi
Division of Pulmonary and Critical Care Medicine, Edward Hines Jr Veterans Administration Hospital, and Loyola University of Chicago Stritch School of Medicine, Hines, IL, USA
Chest 125:2188-95. 2004..As such, neuromechanical coupling estimates the fraction of diaphragmatic capacity used to generate tidal breathing. The present investigation was conducted to determine whether benefit is maintained at 2 years...
Disorders of the respiratory musclesFranco Laghi
Division of Pulmonary and Critical Care Medicine, Edward Hines, JR VA Hospital, 111 N 5th Avenue and Roosevelt Road, Hines, IL 60141, USA
Am J Respir Crit Care Med 168:10-48. 2003..A detailed understanding of disease states affecting the respiratory muscles is necessary for every physician who practices pulmonary medicine or critical care medicine...
Effect of inspiratory time and flow settings during assist-control ventilationFranco Laghi
Division of Pulmonary and Critical Care Medicine, Department of Veterans Affairs Hospital, Loyola University Stritch School of Medicine, Hines, Illinois, USA
Curr Opin Crit Care 9:39-44. 2003....
Is weaning failure caused by low-frequency fatigue of the diaphragm?Franco Laghi
Division of Pulmonary and Critical Care Medicine, Edward Hines Jr Veterans Administration Hospital, Hines, Illinois 60141, USA
Am J Respir Crit Care Med 167:120-7. 2003..In conclusion, in contrast to our hypothesis, weaning failure was not accompanied by low-frequency fatigue of the diaphragm, although many weaning failure patients displayed diaphragmatic weakness...
Sternomastoid, rib cage, and expiratory muscle activity during weaning failureSairam Parthasarathy
Division of Pulmonary and Critical Care Medicine, Edward Hines Jr Veterans Administration Hospital, and Loyola University of Chicago Stritch School of Medicine, Hines, Illinois, USA
J Appl Physiol 103:140-7. 2007..Extradiaphragmatic muscle recruitment may be a mechanism for offsetting the effects of increased load on a weak diaphragm...
Can diaphragmatic contractility be assessed by airway twitch pressure in mechanically ventilated patients?S E Cattapan
Division of Pulmonary and Critical Care Medicine, Edward Hines Jr Veterans Administration Hospital, and Loyola University of Chicago Stritch School of Medicine, Hines, Illinois 60141, USA
Thorax 58:58-62. 2003..Nevertheless, the excellent reproducibility of Paw tw suggests that it may be a useful means of monitoring inspiratory muscle contractility in the routine care of mechanically ventilated patients...
The voluntary drive to breathe is not decreased in hypercapnic patients with severe COPDA Topeli
Division of Pulmonary and Critical Care Medicine, Edward Hines Jr Veterans Administration Hospital, and Loyola University of Chicago Stritch School of Medicine, Hines, IL 60141, USA
Eur Respir J 18:53-60. 2001....
Fluctuations in end-expiratory lung volume during Cheyne-Stokes respirationThomas Brack
Division of Pulmonary and Critical Care Medicine, Edward Hines Jr. VA Hospital, 111N, 5th Avenue and Roosevelt Road, Hines, IL 60141, USA
Am J Respir Crit Care Med 171:1408-13. 2005..48). In conclusion, patients with Cheyne-Stokes respiration exhibit fluctuations in end-expiratory lung volume, primarily because of alterations in tidal volume and expiratory time rather than postinspiratory inspiratory muscle activity...
Microstimulators and intramuscular hook electrodes for the stimulation of respiratory musclesJames S Walter
Research Service, Hines Veterans Administration Hospital, Hines, Illinois 60141, USA
J Spinal Cord Med 30:338-45. 2007..Intramuscular hook electrodes, model microstimulators (M-Micro) developed in our laboratory, and commercial radiofrequency microstimulators (RFM) (Alfred Mann Foundation, Valencia, CA), were employed in this investigation...
Narrative review: ventilator-induced respiratory muscle weaknessMartin J Tobin
Edward Hines Jr Veterans Affairs Hospital, Hines, Illinois 60141, USA
Ann Intern Med 153:240-5. 2010..Research on ventilator-induced respiratory muscle injury is in its infancy and portends to be an exciting area to follow...
Role of the respiratory muscles in acute respiratory failure of COPD: lessons from weaning failureMartin J Tobin
Division of Pulmonary and Critical Care Medicine, Edward Hines Jr VA Hospital, Hines, Illinois 60141, USA
J Appl Physiol 107:962-70. 2009..Although the disease originates within the lung parenchyma, much of the distress faced by patients with COPD, especially during acute respiratory failure, is caused by the burdens imposed on the respiratory muscles...
Weaning prediction: esophageal pressure monitoring complements readiness testingAmal Jubran
Division of Pulmonary and Critical Care Medicine, Edward Hines Jr VA Hospital, 111N 5th Avenue and Roosevelt Road, Hines, IL 60141, USA
Am J Respir Crit Care Med 171:1252-9. 2005..In conclusion, continuous monitoring of esophageal pressure swings during a spontaneous breathing trial provides additional guidance in patient management over tests used for deciding when to initiate weaning...
Effect of ventilation-feedback training on endurance and perceived breathlessness during constant work-rate leg-cycle exercise in patients with COPDEileen G Collins
Research and Development, Nursing, and Medical Services, Department of Veterans Affairs Hospital, Hines, IL 60141, USA
J Rehabil Res Dev 40:35-44. 2003..Based on these preliminary data, VF(+EX) and EX(ONLY) were equally effective in improving leg-cycle exercise tolerance in patients with moderate to severe COPD...
Can ventilation-feedback training augment exercise tolerance in patients with chronic obstructive pulmonary disease?Eileen G Collins
Research and Development 151, Edward Hines, JR VA Hospital, Hines, IL 60141, USA
Am J Respir Crit Care Med 177:844-52. 2008..Objectives: To determine whether patients with COPD would achieve longer exercise duration if randomized to a combination of exercise training plus VF training than either form of training on its own...
Stimulating multiple respiratory muscles with intramuscular Permaloc electrodesJames S Walter
Research Service, Edward Hines Veterans Administration Hospital, Ines, Illinois 60141, USA
J Spinal Cord Med 33:135-43. 2010..To test the feasibility of implanting intramuscular electrodes (Permaloc, Synapse Biomedical Inc, Oberlin OH) with self-securing polypropylene anchors to stimulate upper-intercostal and abdominal muscles plus the diaphragm...
Unilateral expiratory airflow obstruction during forced exhalationUmur Hatipoglu
Division of Pulmonary and Critical Care Medicine, Edward Hines Jr Veterans Affairs Hospital, Illinois 60141, USA
Respir Care 47:693-5. 2002..This case is an elegant illustration of the effects of respiratory maneuvers and body position on airway caliber...
Low testosterone in chronic obstructive pulmonary disease: does it really matter?Franco Laghi
Am J Respir Crit Care Med 172:1069-70. 2005
Evaluation and initial management of acute kidney injuryJonathan Himmelfarb
Division of Nephrology, Maine Medical Center, 22 Bramhall Street, Portland, ME 04102, USA
Clin J Am Soc Nephrol 3:962-7. 2008....
Curing the septic diaphragm with the ventilatorFranco Laghi
Am J Respir Crit Care Med 165:145-6. 2002
Effect of closed unit policy and appointing an intensivist in a developing countryArzu Topeli
Medical Intensive Care Unit, Hacettepe University Faculty of Medicine, Ankara, Turkey
Crit Care Med 33:299-306. 2005..CONCLUSION: A dual strategy of closed policy and simultaneously appointing an intensivist fostered admission of sicker patients and improved the survival of patients requiring admission to an ICU of a developing country...
Potassium sorbate reduces gastric colonization in patients receiving mechanical ventilationAiman Tulaimat
The Division of Pulmonary and Critical Care Medicine, Loyola University, Stritch School of Medicine, Chicago, IL 60611, USA
J Crit Care 20:281-7. 2005..CONCLUSION: Tube feeding formula acidified using potassium sorbate was well tolerated and reduced gastric bacterial burden in patients recovering from prolonged mechanical ventilation...
