R S Cooper

Summary

Affiliation: Loyola University Chicago
Country: USA

Publications

  1. ncbi request reprint Hypertension detection and control: population and policy implications
    Richard S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Medical School, 2160 S First Ave, Maywood, IL 60153, USA
    Cardiol Clin 20:187-94. 2002
  2. ncbi request reprint Social inequality, ethnicity and cardiovascular disease
    R S Cooper
    Department of Preventive Medicine, Loyola University School of Medicine, 2160 S First Ave, Maywood, IL 60153, USA
    Int J Epidemiol 30:S48-52. 2001
  3. ncbi request reprint Heritability of angiotensin-converting enzyme and angiotensinogen: A comparison of US blacks and Nigerians
    R S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, IL 60153, USA
    Hypertension 35:1141-7. 2000
  4. ncbi request reprint Racial differences and the genetics of hypertension
    R S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, IL 60153, USA
    Curr Hypertens Rep 3:19-24. 2001
  5. ncbi request reprint Prevalence of NIDDM among populations of the African diaspora
    R S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Illinois 60153, USA
    Diabetes Care 20:343-8. 1997
  6. pmc Patterns of sodium and potassium excretion and blood pressure in the African Diaspora
    B O Tayo
    Department of Preventive Medicine and Epidemiology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 60153, USA
    J Hum Hypertens 26:315-24. 2012
  7. ncbi request reprint Association of waist circumference with risk of hypertension and type 2 diabetes in Nigerians, Jamaicans, and African-Americans
    I S Okosun
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Illinois 60153, USA
    Diabetes Care 21:1836-42. 1998
  8. ncbi request reprint The relation of central adiposity to components of the insulin resistance syndrome in a biracial US population sample
    I S Okosun
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Stritch School of Medicine, Maywood, Illinois 60153, USA
    Ethn Dis 9:218-29. 1999
  9. ncbi request reprint Relationship between blood pressure and body mass index in lean populations
    J S Kaufman
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Ill, USA
    Hypertension 30:1511-6. 1997
  10. ncbi request reprint Weight-height relationships among eight populations of West African origin: the case against constant BMI standards
    A E Long
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    Int J Obes Relat Metab Disord 22:842-6. 1998

Detail Information

Publications93

  1. ncbi request reprint Hypertension detection and control: population and policy implications
    Richard S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Medical School, 2160 S First Ave, Maywood, IL 60153, USA
    Cardiol Clin 20:187-94. 2002
    ..Improvement in information technology, including an electronic medical record and on-line risk equations, will also be required before its full value can be realized...
  2. ncbi request reprint Social inequality, ethnicity and cardiovascular disease
    R S Cooper
    Department of Preventive Medicine, Loyola University School of Medicine, 2160 S First Ave, Maywood, IL 60153, USA
    Int J Epidemiol 30:S48-52. 2001
    ..Large differentials remain among socio-demographic groups, however, and the causes of these differentials may be distinctly different from those observed at the individual level...
  3. ncbi request reprint Heritability of angiotensin-converting enzyme and angiotensinogen: A comparison of US blacks and Nigerians
    R S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, IL 60153, USA
    Hypertension 35:1141-7. 2000
    ..Variation in heritability of traits could influence the power of epidemiological studies to identify genetic effects...
  4. ncbi request reprint Racial differences and the genetics of hypertension
    R S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, IL 60153, USA
    Curr Hypertens Rep 3:19-24. 2001
    ..Despite rapid progress, this work is still in its infancy and raises more questions than it answers...
  5. ncbi request reprint Prevalence of NIDDM among populations of the African diaspora
    R S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Illinois 60153, USA
    Diabetes Care 20:343-8. 1997
    ..K. Increases in risk have likewise been observed in the island nations of the Caribbean and in urban West Africa. To date, however, no systematic comparison of the geographic variation of NIDDM among black populations has been undertaken...
  6. pmc Patterns of sodium and potassium excretion and blood pressure in the African Diaspora
    B O Tayo
    Department of Preventive Medicine and Epidemiology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 60153, USA
    J Hum Hypertens 26:315-24. 2012
    ..These data confirm the consistency with the possible role of dietary electrolytes as hypertension risk factors, reinforcing the relevance of potassium in these populations...
  7. ncbi request reprint Association of waist circumference with risk of hypertension and type 2 diabetes in Nigerians, Jamaicans, and African-Americans
    I S Okosun
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Illinois 60153, USA
    Diabetes Care 21:1836-42. 1998
    ..In this study, we reexamine the role of waist size on the risk of hypertension and type 2 diabetes in African-origin populations from three contrasting environments...
  8. ncbi request reprint The relation of central adiposity to components of the insulin resistance syndrome in a biracial US population sample
    I S Okosun
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Stritch School of Medicine, Maywood, Illinois 60153, USA
    Ethn Dis 9:218-29. 1999
    ..The results of this study reinforce the need to encourage the use of waist measure as a public health tool in screening for CVD risks...
  9. ncbi request reprint Relationship between blood pressure and body mass index in lean populations
    J S Kaufman
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Ill, USA
    Hypertension 30:1511-6. 1997
    ..In summary, we observed a threshold at 21 kg/m2 in the relationship between BMI and BP for women but not for men. This contributes to the effort to identify the mechanisms that underlie this relationship and how they differ by gender...
  10. ncbi request reprint Weight-height relationships among eight populations of West African origin: the case against constant BMI standards
    A E Long
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    Int J Obes Relat Metab Disord 22:842-6. 1998
    ..CONCLUSION: The use of constant BMI standards in classifying individuals prognostically may be unwise, even in genetically similar populations...
  11. ncbi request reprint Abdominal adiposity in six populations of West African descent: prevalence and population attributable fraction of hypertension
    I S Okosun
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Stritch School of Medicine, Maywood, IL 60153, USA
    Obes Res 7:453-62. 1999
    ..Lucia, Barbados, and the United States (US)...
  12. ncbi request reprint Comparability of resting energy expenditure in Nigerians and U.S. blacks
    A Luke
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Illinois 60153, USA
    Obes Res 8:351-9. 2000
    ..To determine the influence of environmental factors on resting energy expenditure (REE) and its relationship to adiposity in two populations of West African origin, Nigerians and U.S. blacks...
  13. pmc Socioeconomic status and morbidity in the last years of life
    Y Liao
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Ill 60153, USA
    Am J Public Health 89:569-72. 1999
    ..This study evaluated the effect of socioeconomic status, as characterized by level of education, on morbidity and disability in the last years of life...
  14. ncbi request reprint Association of waist circumference with ApoB to ApoAI ratio in black and white Americans
    I S Okosun
    Department of Preventive Medicine and Epidemiology, Loyola University Chicago Medical Center, Stritch School of Medicine, Maywood, IL 60153, USA
    Int J Obes Relat Metab Disord 23:498-504. 1999
    ..In this study, we examined the relationship between central fat distribution (defined by waist circumference) and the ratio of these lipoproteins (ApoB/ApoAI)...
  15. ncbi request reprint Heritability of obesity-related traits among Nigerians, Jamaicans and US black people
    A Luke
    Department of Preventive Medicine and Epidemiology, Loyola University School of Medicine, Maywood, Illinois 60153, USA
    Int J Obes Relat Metab Disord 25:1034-41. 2001
    ..To examine whether heritability is influenced by socio-cultural factors, we conducted a cross-cultural study of populations of the African diaspora...
  16. pmc Localization of a small genomic region associated with elevated ACE
    X Zhu
    Department of Preventive Medicine, Loyola University Chicago, Maywood, IL, 60153, USA
    Am J Hum Genet 67:1144-53. 2000
    ....
  17. ncbi request reprint Prevalence of diabetes and impaired glucose tolerance in Nigerians, Jamaicans and US blacks
    C N Rotimi
    Department of Preventive Medicine and Epidemiolgy, Loyola University Stritch School of Medicine, Maywood, IL 60153, USA
    Ethn Dis 9:190-200. 1999
    ..Nigerians exhibited remarkably well-preserved glucose tolerance. Understanding the factors that limit the risk of type 2 diabetes in West Africa, beyond relative absence of obesity, would have considerable public health significance...
  18. ncbi request reprint Leptin and body composition of Nigerians, Jamaicans, and US blacks
    A H Luke
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, IL 60153, USA
    Am J Clin Nutr 67:391-6. 1998
    ..These findings likewise confirm that men and women exhibit different set points in terms of leptin production...
  19. ncbi request reprint Maximum-likelihood generalized heritability estimate for blood pressure in Nigerian families
    C N Rotimi
    Loyola University Medical Center, Department of Preventive Medicine and Epidemiology, Maywood, Ill 60153, USA
    Hypertension 33:874-8. 1999
    ..However, the heritability estimate of <50% for both SBP and DBPs reinforces the importance of the nonshared environmental effect...
  20. ncbi request reprint Mortality from coronary heart disease and cardiovascular disease among adult U.S. Hispanics: findings from the National Health Interview Survey (1986 to 1994)
    Y Liao
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Illinois 60153, USA
    J Am Coll Cardiol 30:1200-5. 1997
    ..We sought to estimate the coronary heart disease (CHD) and cardiovascular disease (CVD) mortality experience of U.S. Hispanics...
  21. ncbi request reprint Predictive value of abdominal obesity cut-off points for hypertension in blacks from west African and Caribbean island nations
    I S Okosun
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Stritch School of Medicine, Maywood, Illinois 60153, USA
    Int J Obes Relat Metab Disord 24:180-6. 2000
    ..We also determined population- and gender-specific abdominal adiposity cut-off points for epidemiological identification of risk of hypertension...
  22. pmc Latent common genetic components of obesity traits
    B O Tayo
    Department of Preventive Medicine and Epidemiology, Loyola University Chicago, Stritch School of Medicine, Maywood, IL 60153, USA
    Int J Obes (Lond) 32:1799-806. 2008
    ..Obesity is rapidly becoming a global epidemic. Unlike many complex human diseases, obesity is defined not just by a single trait or phenotype, but jointly by measures of anthropometry and metabolic status...
  23. ncbi request reprint Localization of the Q1 mutation by cladistic analysis
    X Zhu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, 2160 S. First Ave, Maywood, IL 60153, USA
    Genet Epidemiol 21:S594-9. 2001
    ..The Q1 mutation was localized to a 5-kb segment, in which the true mutation is located. Our analysis shows that cladistic analysis, which summarizes evolutionary history, can be a powerful tool in gene mapping...
  24. ncbi request reprint Prediction of mortality risk by different methods of indexation for left ventricular mass
    Y Liao
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, Illinois 60153, USA
    J Am Coll Cardiol 29:641-7. 1997
    ..We sought to compare the predictive value of echocardiographically determined left ventricular hypertrophy on death from all causes and cardiac mortality using various methods of indexation for left ventricular mass...
  25. pmc Relationship between premature mortality and socioeconomic factors in black and white populations of US metropolitan areas
    R S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Medical School, Maywood, IL 60153, USA
    Public Health Rep 116:464-73. 2001
    ..The primary aim of the analysis was to operationalize the concept of institutional racism in public health...
  26. ncbi request reprint Prediction of coronary heart disease mortality in blacks and whites: pooled data from two national cohorts
    Y Liao
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Illinois 60153, USA
    Am J Cardiol 84:31-6. 1999
    ..Thus, predictive functions derived from 1 demographic group (e.g., whites) can be applied to another subgroup (e.g., blacks) to rank personal risk. However, prediction of absolute risk is less accurate...
  27. ncbi request reprint Nutritional consequences of the African diaspora
    A Luke
    Department of Preventive Medicine and Epidemiology, Loyola University School of Medicine, Maywood, Illinois 60153, USA
    Annu Rev Nutr 21:47-71. 2001
    ..Fortunately, a coherent and well-supported set of recommendations exists to promote better nutrition. Implementation of it founders primarily as a result of the influence of commercial and political interests...
  28. ncbi request reprint Testing quantitative traits for association and linkage in the presence or absence of parental data
    X Zhu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, Ill 60153, USA
    Hum Hered 51:183-91. 2001
    ..In practice, the data may have some families with parental phenotype and genotype information available and some without. We briefly discuss how all the data may be analyzed jointly...
  29. pmc Linkage and association analysis of angiotensin I-converting enzyme (ACE)-gene polymorphisms with ACE concentration and blood pressure
    X Zhu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    Am J Hum Genet 68:1139-48. 2001
    ..Furthermore, allelic interaction may play an important role in the dissection of complex traits such as BP...
  30. ncbi request reprint Relationship between blood pressure and physical activity assessed with stable isotopes
    A Luke
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    J Hum Hypertens 19:127-32. 2005
    ..In conclusion these data suggest that habitual levels of physical activity may have a generalizable relationship with BP in populations with widely different social and environmental characteristics...
  31. ncbi request reprint Mortality among US adult Asians and Pacific Islanders: findings from the National Health Interview Surveys and the National Longitudinal Mortality Study
    Y Liao
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Illinois 60153, USA
    Ethn Dis 9:423-33. 1999
    ..To assess the mortality of the adult Asian and Pacific Islander population in the United States...
  32. ncbi request reprint Absence of black-white differences in sodium and calcium in platelets
    R S Cooper
    Department of Preventive Medicine, Loyola Stritch School of Medicine, Maywood, Illinois 60153, USA
    Am J Hypertens 8:558-64. 1995
    ..05). Red cells may be atypical for studies of calcium and sodium homeostasis, and their relevance for interethnic studies of causal pathways in hypertension should be reconsidered...
  33. doi request reprint Which factors confound or modify the relationship between body weight and mortality?
    R S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Chicago, Maywood, IL 60153, USA
    Int J Obes (Lond) 32:S47-51. 2008
    ..A large-scale social experiment is cited that gives some evidence on the effect of a population-wide downward shift in BMI...
  34. ncbi request reprint Activity, adiposity and weight change in Jamaican adults
    A Luke
    Department of Preventitive Medicine and Epidemiology, Loyola University Medical Centre, Maywood, IL 60153, USA
    West Indian Med J 56:398-403. 2007
    ..We sought to determine the relationship between activity energy expenditure (AEE), adiposity and weight change in an adult population undergoing rapid socio-economic transition...
  35. doi request reprint Issues related to modeling the body mass index-mortality association: the shape of the association and the effects of smoking status
    R A Durazo-Arvizu
    Department of Preventive Medicine and Epidemiology, Loyola University, Maywood, IL 60153, USA
    Int J Obes (Lond) 32:S52-5. 2008
    ..The association between BMI and mortality is not changed when smoking status is ignored in a model or when data on smokers are excluded from analysis. The methodology used in this study could be extended to look for other interactions...
  36. pmc Coronary angiographic findings in African-American and white patients from a single institution
    Y Liao
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Illinois 60153, USA
    J Natl Med Assoc 93:465-74. 2001
    ..The African-American:white differences in angiographic findings were minimal in younger men and in women. However, African Americans had worse clinical profiles than whites...
  37. ncbi request reprint Quality of the last year of life of older adults: 1986 vs 1993
    Y Liao
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, IL 60153, USA
    JAMA 283:512-8. 2000
    ..The population is aging and life expectancy is increasing, but whether morbidity and disability late in life also increase is unknown...
  38. pmc Limitations in the use of race in the study of disease causation
    R S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, IL 60153, USA
    J Natl Med Assoc 91:379-83. 1999
    ..Finally, the "grand" theories of race-based genetic susceptibility must be replaced with rigorous criteria to determine when a trait can be ascribed to some genetic origin...
  39. pmc The absence of adult mortality data for sub-Saharan Africa: a practical solution
    J S Kaufman
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, IL 60153, USA
    Bull World Health Organ 75:389-95. 1997
    ..This method is discussed in the present article, and practical considerations for longitudinal studies using this methodology are reviewed...
  40. pmc Voluntary participation and informed consent to international genetic research
    Patricia A Marshall
    Department of Bioethics, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 4976, USA
    Am J Public Health 96:1989-95. 2006
    ..We compared voluntary participation and comprehension of informed consent among individuals of African ancestry enrolled in similarly designed genetic studies of hypertension in the United States and Nigeria...
  41. ncbi request reprint A genome-wide scan of loci linked to serum adiponectin in two populations of African descent
    Chindo Hicks
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, 1219 Roosevelt Road, Maywood, IL 60153, USA
    Obesity (Silver Spring) 15:1207-14. 2007
    ..The objectives were to identify quantitative trait loci linked to serum adiponectin concentration and to estimate heritability in two populations of African descent...
  42. ncbi request reprint Meta-analysis of genome-wide scans for blood pressure in African American and Nigerian samples. The National Heart, Lung, and Blood Institute GeneLink Project
    Treva Rice
    Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri, USA
    Am J Hypertens 19:270-4. 2006
    ..However, the combined linkage evidence across several studies can be synthesized using meta-analysis with the aim of providing more definitive support of linkage...
  43. ncbi request reprint Ethnicity, education, and blood pressure in Cuba
    Pedro Ordunez
    Department of Public Health, Faculty of Medical Sciences, University Hospital Dr Gustavo Aldereguía Lima, Cienfuegos, Cuba
    Am J Epidemiol 162:49-56. 2005
    ....
  44. ncbi request reprint Genetic effects on blood pressure localized to chromosomes 6 and 7
    Adebowale Adeyemo
    Department of Pediatrics Institute of Child Health, College of Medicine, University of Ibadan, Ibadan, Nigeria
    J Hypertens 23:1367-73. 2005
    ..To identify quantitative trait loci (QTL) contributing to the variation in blood pressure in a west African population...
  45. ncbi request reprint Discovering the full spectrum of cardiovascular disease: Minority Health Summit 2003: report of the Obesity, Metabolic Syndrome, and Hypertension Writing Group
    Sidney C Smith
    Circulation 111:e134-9. 2005
  46. pmc Body size and blood pressure: an analysis of Africans and the African diaspora
    Francesco P Cappuccio
    Clinical Sciences Research Institute, Warwick Medical School, Coventry, UK
    Epidemiology 19:38-46. 2008
    ..Blood pressure is directly and causally associated with body mass index (BMI) in populations worldwide. However, the relationship may vary across BMI in populations of African origin...
  47. ncbi request reprint An association study of angiotensinogen polymorphisms with serum level and hypertension in an African-American population
    Xiaodong Wu
    Department of Preventive Medicine and Epidemiology, Loyola Stritch School of Medicine, Maywood, Illinois 60153, USA
    J Hypertens 21:1847-52. 2003
    ..To evaluate the association of angiotensinogen (AGT) gene with AGT level and hypertension based on the overall genetic variation of the AGT gene in among African-Americans...
  48. ncbi request reprint A genome-wide linkage analysis investigating the determinants of blood pressure in whites and African Americans
    Bonnie A Thiel
    Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA
    Am J Hypertens 16:151-3. 2003
    ..0057 and .00023, respectively) was found on chromosome 1. Our results support the idea that BP regulation is most likely governed by multiple genetic loci, each with a relatively weak effect on BP in the population at large...
  49. ncbi request reprint A genome-wide scan for obesity in African-Americans
    Xiaofeng Zhu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical School, Maywood, Illinois 60153, USA
    Diabetes 51:541-4. 2002
    ..The replication of linkage evidence using different ethnic groups reinforces the potential significance of this latter candidate region...
  50. pmc An international comparative study of blood pressure in populations of European vs. African descent
    Richard S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, IL, USA
    BMC Med 3:2. 2005
    ..Large surveys now provide new information on this issue...
  51. pmc A combined analysis of genomewide linkage scans for body mass index from the National Heart, Lung, and Blood Institute Family Blood Pressure Program
    Xiaodong Wu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    Am J Hum Genet 70:1247-56. 2002
    ....
  52. ncbi request reprint Genome scan among Nigerians linking blood pressure to chromosomes 2, 3, and 19
    Richard S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola Medical School, Maywood, Ill 60153, USA
    Hypertension 40:629-33. 2002
    ..Study designs that make it possible to confirm these results with association analysis and narrow the genomic interval are needed in order to make progress in this field...
  53. ncbi request reprint Activity energy expenditure and adiposity among black adults in Nigeria and the United States
    Amy Luke
    Department of Preventive Medicine and Epidemiology, Loyola University School of Medicine, Maywood, IL 60153, USA
    Am J Clin Nutr 75:1045-50. 2002
    ..The prevalence of obesity is higher among populations in industrialized than in developing countries...
  54. pmc An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertension
    Gen Wen
    Department of Medicine, Moores UCSD Cancer Center, University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Hum Mol Genet 16:1752-64. 2007
    ..These results identify a common regulatory variation in SCG2 and implicate granin gene expression in the control of human blood pressure and susceptibility to hypertension...
  55. ncbi request reprint Efficacy of angiotensin-converting enzyme inhibition in reducing progression from asymptomatic left ventricular dysfunction to symptomatic heart failure in black and white patients
    Daniel L Dries
    Heart Failure Research Group, Cardiology Division, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9034, USA
    J Am Coll Cardiol 40:311-7. 2002
    ..This study was undertaken to determine whether enalapril had comparable efficacy in black and white patients with asymptomatic left ventricular dysfunction (ALVD) in preventing the development of symptomatic heart failure (HF)...
  56. pmc The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts
    Helen N Lyon
    Program in Genomics, Divisions of Genetics and Endocrinology, Children s Hospital, Boston, Massachusetts, USA
    PLoS Genet 3:e61. 2007
    ....
  57. ncbi request reprint Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men
    Catarina D Campbell
    Program in Genomics and Division of Endocrinology, Children s Hospital, Boston, Massachusetts 021115, USA
    Diabetes 56:1460-7. 2007
    ..73 x 10(-4), OR = 1.36) and not in women. Variation in this pathway likely does not have a major influence on BMI, although small effects cannot be ruled out; NPY2R should be considered a candidate gene for type 2 diabetes in men...
  58. ncbi request reprint Using public health indicators to measure the success of hypertension control
    Richard S Cooper
    Hypertension 49:773-4. 2007
  59. ncbi request reprint Corin I555(P568) allele is associated with enhanced cardiac hypertrophic response to increased systemic afterload
    J Eduardo Rame
    Division of Cardiology, University of California San Francisco, USA
    Hypertension 49:857-64. 2007
    ..These data suggest that the corin I555(P568) allele represents a cardiac hypertrophy-sensitizing genetic locus in systemic hypertension...
  60. pmc Multiple genes for essential-hypertension susceptibility on chromosome 1q
    YEN PEI CHRISTY CHANG
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Am J Hum Genet 80:253-64. 2007
    ..Because the associated alleles in these genes are relatively common (frequency >5%), these three genes are important contributors to elevated BP in the population at large...
  61. ncbi request reprint Isoprostanes, a marker of lipid peroxidation, may not be involved in the development of glucose intolerance
    Michael S Boyne
    Tropical Medicine Research Institute, University of the West Indies, Mona, Jamaica
    Diabetes Res Clin Pract 76:149-51. 2007
    ..Isoprostanes were not significantly associated with IS or BCF (p-values>0.1). We concluded that isoprostanes may not be causally involved in the development of glucose intolerance, insulin resistance or deteriorating BCF...
  62. pmc Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
    Angelo Scuteri
    Unità Operativa Geriatria, Istituto per la Patologia Endocrina e Metabolica, Rome, Italy
    PLoS Genet 3:e115. 2007
    ..These changes could have a significant impact on the risk of obesity-related morbidity in the general population...
  63. pmc Admixture mapping provides evidence of association of the VNN1 gene with hypertension
    Xiaofeng Zhu
    Department of Epidemiology and Biostatistics, School of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America
    PLoS ONE 2:e1244. 2007
    ..Despite these encouraging results, susceptibility loci for hypertension have been exceptionally difficult to localize and confirmation by independent studies will be necessary to establish these findings...
  64. ncbi request reprint The feasibility of implementing a dietary sodium reduction intervention among free-living normotensive individuals in south west Nigeria
    Adebowale A Adeyemo
    College of Medicine, University of Ibadan, Nigeria
    Ethn Dis 12:207-12. 2002
    ....
  65. doi request reprint Risk factors associated with uncontrolled hypertension: findings from the baseline CARMEN survey in Cienfuegos, Cuba
    Pedro Ordunez
    Hospital Universitario Dr Gustavo Aldereguía Lima, Cienfuegos, Cuba
    J Hypertens 26:663-71. 2008
    ..The probability of having inadequate control varies widely in the population and better understanding of the factors responsible could help to focus treatment strategies...
  66. pmc Obesity reduction and its possible consequences: what can we learn from Cuba's Special Period?
    Manuel Franco
    Department of Epidemiology and the Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    CMAJ 178:1032-4. 2008
  67. pmc Rapid increases in obesity in Jamaica, compared to Nigeria and the United States
    Ramon A Durazo-Arvizu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical School, Maywood, IL, USA
    BMC Public Health 8:133. 2008
    ..To examine the rate of change across the spectrum of low to high-income countries we compared rates of weight change in samples drawn from three countries, Nigeria, Jamaica and the United States...
  68. doi request reprint Blacks and whites have a similar prevalence of reduced left ventricular ejection fraction in the general population: the Dallas Heart Study (DHS)
    David W Markham
    Donald W Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390 9047, USA
    Am Heart J 155:876-82. 2008
    ..Because of the higher prevalence of risk factors for heart failure in blacks, including hypertension, obesity, and LV hypertrophy, we hypothesized that LV dysfunction would also be more common in this ethnic group...
  69. doi request reprint Neighborhood characteristics and hypertension
    Mahasin S Mujahid
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48104, USA
    Epidemiology 19:590-8. 2008
    ..The goal of this study was to investigate cross-sectional associations between features of neighborhoods and hypertension and to examine the sensitivity of results to various methods of estimating neighborhood conditions...
  70. ncbi request reprint Heritability of blood pressure in Nigerian families
    Adebowale A Adeyemo
    College of Medicine, University of Ibadan, Ibadan, Nigeria
    J Hypertens 20:859-63. 2002
    ..This study was undertaken to provide estimates of heritability for four blood pressure phenotypes: systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) and pulse pressure...
  71. ncbi request reprint RE: Hirsch C, Anderson ML, Newman A, Kop W, Jackson S, Gottdiener J, et al, for the Cardiovascular Health Study Research Group. The association of race with frailty: The Cardiovascular Health Study. Ann Epidemiol. 2006;16:545-553
    Jay S Kaufman
    Ann Epidemiol 17:157-8. 2007
  72. ncbi request reprint Predicting incident diabetes in Jamaica: the role of anthropometry
    Lincoln A Sargeant
    Tropical Medicine Research Institute, University of the West Indies, Mona, Jamaica
    Obes Res 10:792-8. 2002
    ..To evaluate the performance of the body mass index (BMI), waist circumference, waist-to-hip ratio (WHR), and waist-to-height ratio (WHTR) in predicting incident diabetes in Jamaica...
  73. ncbi request reprint Task force #1--magnitude of the prevention problem: opportunities and challenges. 33rd Bethesda Conference
    Emelia J Benjamin
    Boston University School of Medicine, The Framingham Heart Study, MA 01702 5827, USA
    J Am Coll Cardiol 40:588-603. 2002
  74. pmc Linkage disequilibrium and haplotype diversity in the genes of the renin-angiotensin system: findings from the family blood pressure program
    Xiaofeng Zhu
    Department of Preventive Medicine and Epidemiology, Loyola Stritch School of Medicine, Maywood, Illinois 60153, USA
    Genome Res 13:173-81. 2003
    ..These findings have implications for candidate-gene association studies and indicate that variation between populations of European and African origin in haplotype diversity is characteristic of most genes...
  75. ncbi request reprint Association between evolutionary history of angiotensinogen haplotypes and plasma levels
    Laura Fejerman
    Department of Biological Anthropology, Oxford University, Oxford, UK
    Hum Genet 115:310-8. 2004
    ..A significant linear correlation was detected between haplogroup genetic distance and AGT levels, suggesting a nonrandom accumulation of risk-associated mutations during the evolutionary history of the AGT gene...
  76. ncbi request reprint A genome scan among Nigerians linking resting energy expenditure to chromosome 16
    Xiaodong Wu
    Department of Preventive Medicine and Epidemiology, Loyola Medical School, Maywood, Illinois 60153, USA
    Obes Res 12:577-81. 2004
    ..3) with a likelihood of odds of 2.96 (p = 0.08). Linkage evidence (likelihood of odds > 1) was detected on another three chromosomal regions, namely 2q12.1, 8q21.2, and 15p11.2...
  77. ncbi request reprint Angiotensin I-converting enzyme polymorphisms, ACE level and blood pressure among Nigerians, Jamaicans and African-Americans
    Nourdine Bouzekri
    Department of Biological Anthropology, University of Oxford, Oxford, UK
    Eur J Hum Genet 12:460-8. 2004
    ..We did observe, however, that the overtransmitted haplotypes among hypertensives were drawn from a single clade, suggesting that susceptibility may cluster in patterns not captured directly by our markers...
  78. ncbi request reprint Association between blood pressure and resting energy expenditure independent of body size
    Amy Luke
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    Hypertension 43:555-60. 2004
    ..The interrelationship of REE with sympathetic tone, transmembrane ion exchange, or other metabolic processes that determine energy costs at rest could provide physiological explanations for this observation...
  79. ncbi request reprint Positional identification of hypertension susceptibility genes on chromosome 2
    Ruth Ann Barkley
    Human Genetics Center and Institute of Molecular Medicine, of Texas Health Science Center at Houston, USA
    Hypertension 43:477-82. 2004
    ..Moreover, the present study validates previous evidence for one or more genes on chromosome 2 that influence hypertension-related phenotypes in the population-at-large...
  80. ncbi request reprint Hypertension treatment and control in five European countries, Canada, and the United States
    Katharina Wolf-Maier
    Department of Preventive Medicine and Epidemiology, Stritch School of Medicine, Loyola University, 2160 S First Ave, Maywood, Ill 60153, USA
    Hypertension 43:10-7. 2004
    ..Low treatment and control rates in Europe, combined with a higher prevalence of hypertension, could contribute to a higher burden of cardiovascular disease risk attributable to elevated blood pressure compared with that in North America...
  81. ncbi request reprint High blood pressure: the foundation for epidemic cardiovascular disease in African populations
    Richard S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Illinois 60153, USA
    Ethn Dis 13:S48-52. 2003
    ..It will be critical to obtain investments in improved surveillance and program-relevant research to provide the evidence base for policy development and effective hypertension prevention and control...
  82. ncbi request reprint Combined analysis of genomewide scans for adult height: results from the NHLBI Family Blood Pressure Program
    Xiaodong Wu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153, USA
    Eur J Hum Genet 11:271-4. 2003
    ..46), which has been reported in two previous studies. Suggestive linkage (LOD>1) was found in another six regions in our combined analysis. Evidence for linkage for two of these regions (2p12, 20p11) has also been reported previously...
  83. ncbi request reprint Admixture mapping for hypertension loci with genome-scan markers
    Xiaofeng Zhu
    Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, 2160 S First Ave, Maywood, Illinois 60153, USA
    Nat Genet 37:177-81. 2005
    ..These results suggest that chromosome 6q24 and 21q21 may contain genes influencing risk of hypertension in African Americans...
  84. ncbi request reprint Isosorbide dinitrate and hydralazine in blacks with heart failure
    Andrew E Moran
    N Engl J Med 352:1041-3; author reply 1041-3. 2005
  85. ncbi request reprint Success in control of hypertension in a low-resource setting: the Cuban experience
    Pedro Orduñez-García
    Hospital Universitario Dr Gustavo Aldereguía Lima, Cienfuegos, Cuba
    J Hypertens 24:845-9. 2006
    ..Cuba has a well-organized primary-care system and has made reduction of cardiovascular diseases a priority, particularly through detection and treatment of hypertension...
  86. ncbi request reprint An updated meta-analysis of genome scans for hypertension and blood pressure in the NHLBI Family Blood Pressure Program (FBPP)
    Xiaodong Wu
    Department of Preventive Medicine and Epidemiology, Loyola University Chicago Medical Center, 2160 S First Avenue, Maywood, IL 60153, USA
    Am J Hypertens 19:122-7. 2006
    ..Strong evidence for linkage at two of these regions, 2p14 and 3p14.1, have also been published in previous meta-analyses, making them good candidate locations for susceptibility variants...
  87. ncbi request reprint Epithelial sodium channel allele T594M is not associated with blood pressure or blood pressure response to amiloride
    John M Hollier
    Division of Hypertension, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390 8857, USA
    Hypertension 47:428-33. 2006
    ..8). We conclude that the T594M allele does not contribute significantly to BP in blacks and does not predict a significantly superior response to amiloride therapy...
  88. ncbi request reprint Should ethnicity serve as the basis for clinical trial design? Diversity and inclusiveness should remain the guiding principles for clinical trials
    Richard S Cooper
    Department of Preventive Medicine and Epidemiology, Loyola Stritch School of Medicine, Maywood, IL 60153, USA
    Circulation 112:3660-5; discussion 3665-6. 2005
  89. ncbi request reprint Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension
    Daniel L Dries
    Donald W Reynolds Cardiovascular Clinical Research Center, Division of Cardiology, University of Texas at Southwestern Medical Center, Dallas, USA
    Circulation 112:2403-10. 2005
    ..The natriuretic peptide system contributes to blood pressure regulation. Atrial and brain natriuretic peptides are cleaved into smaller biologically active molecules by corin, a transmembrane serine protease expressed in cardiomyocytes...
  90. ncbi request reprint Linkage disequilibrium analysis of the renin-angiotensin system genes
    Xiaofeng Zhu
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, 2160 S First Ave, Maywood, IL 60153, USA
    Curr Hypertens Rep 5:40-6. 2003
    ..In this review, the linkage disequilibrium among the polymorphisms within the four RAS genes and current association analyses involving the RAS are discussed, as well as some of the gaps of knowledge and possible solutions...
  91. ncbi request reprint A meta-analysis of genome-wide linkage scans for hypertension: the National Heart, Lung and Blood Institute Family Blood Pressure Program
    Michael A Province
    Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Hypertens 16:144-7. 2003
    ..The networks used different family designs and targeted multiple ethnic groups, using standardized protocols and definitions. Linkage genome scans were done on samples within each network (N = 6245 relatives)...
  92. ncbi request reprint Left ventricular hypertrophy is more prevalent in blacks than whites in the general population: the Dallas Heart Study
    Mark H Drazner
    Donald W Reynolds Cardiovascular Clinical Research Center, Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Hypertension 46:124-9. 2005
    ..The ethnic differences in left ventricular mass are independent of differences in body composition...
  93. ncbi request reprint Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States
    Katharina Wolf-Maier
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Ill 60153, USA
    JAMA 289:2363-9. 2003
    ..Geographic variations in cardiovascular disease (CVD) and associated risk factors have been recognized worldwide. However, little attention has been directed to potential differences in hypertension between Europe and North America...