J M Benson

Summary

Affiliation: Lovelace Respiratory Research Institute
Country: USA

Publications

  1. ncbi request reprint Uptake, tissue distribution, and excretion of brevetoxin 3 administered to rats by intratracheal instillation
    J M Benson
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87185, USA
    J Toxicol Environ Health A 57:345-55. 1999
  2. doi request reprint The acute toxicity, tissue distribution, and histopathology of inhaled ricin in Sprague Dawley rats and BALB/c mice
    Janet M Benson
    Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA
    Inhal Toxicol 23:247-56. 2011
  3. doi request reprint Chronic carcinogenicity study of gasoline vapor condensate (GVC) and GVC containing methyl tertiary-butyl ether in F344 rats
    Janet M Benson
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA
    J Toxicol Environ Health A 74:638-57. 2011
  4. pmc Time course of lesion development in the hairless guinea-pig model of sulfur mustard-induced dermal injury
    Janet M Benson
    CounterAct Research Center of Excellence, Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA
    Wound Repair Regen 19:348-57. 2011
  5. pmc Brevetoxin inhalation alters the pulmonary response to influenza A in the male F344 rat
    Janet M Benson
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA
    J Toxicol Environ Health A 74:313-24. 2011
  6. pmc Placental transport of brevetoxin-3 in CD-1 mice
    Janet M Benson
    Lovelace Respiratory Research Institute, 2425 Ridgecrest Dr SE, Albuquerque NM 87108, USA
    Toxicon 48:1018-26. 2006
  7. doi request reprint Uptake, tissue distribution, and excretion of 14C-sulfur mustard vapor following inhalation in F344 rats and cutaneous exposure in hairless guinea pigs
    Janet M Benson
    CounterAct Research Center of Excellence, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA
    J Toxicol Environ Health A 74:875-85. 2011
  8. pmc Inhalation toxicity of brevetoxin 3 in rats exposed for twenty-two days
    Janet M Benson
    Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA
    Environ Health Perspect 113:626-31. 2005
  9. pmc The toxicity of microcystin LR in mice following 7 days of inhalation exposure
    Janet M Benson
    Lovelace Respiratory Research Institute, 2425 Ridgecrest Dr SE, Albuquerque, NM 87108, USA
    Toxicon 45:691-8. 2005
  10. ncbi request reprint Uptake, tissue distribution, and fate of inhaled carbon tetrachloride: comparison of rat, mouse, and hamster
    J M Benson
    Lovelace Respiratory Research Institute, PO Box 5890, Albuquerque, NM 87185 5890, USA
    Inhal Toxicol 13:207-17. 2001

Detail Information

Publications24

  1. ncbi request reprint Uptake, tissue distribution, and excretion of brevetoxin 3 administered to rats by intratracheal instillation
    J M Benson
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87185, USA
    J Toxicol Environ Health A 57:345-55. 1999
    ....
  2. doi request reprint The acute toxicity, tissue distribution, and histopathology of inhaled ricin in Sprague Dawley rats and BALB/c mice
    Janet M Benson
    Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA
    Inhal Toxicol 23:247-56. 2011
    ..Results of this study demonstrate differences exist in pulmonary deposition, clearance rates, and tissue dose and histopathological changes between rats and mice inhaling ricin...
  3. doi request reprint Chronic carcinogenicity study of gasoline vapor condensate (GVC) and GVC containing methyl tertiary-butyl ether in F344 rats
    Janet M Benson
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA
    J Toxicol Environ Health A 74:638-57. 2011
    ....
  4. pmc Time course of lesion development in the hairless guinea-pig model of sulfur mustard-induced dermal injury
    Janet M Benson
    CounterAct Research Center of Excellence, Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA
    Wound Repair Regen 19:348-57. 2011
    ..Erythema, edema, and histologic changes are consistent with findings among human victims of SM attack. This model, with observations to 2 weeks, will be useful in assessing the efficacy of countermeasures against SM...
  5. pmc Brevetoxin inhalation alters the pulmonary response to influenza A in the male F344 rat
    Janet M Benson
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA
    J Toxicol Environ Health A 74:313-24. 2011
    ..These results suggest that repeated inhalation exposure to brevetoxin may delay virus particle clearance and recovery from influenza A infection in the rat lung...
  6. pmc Placental transport of brevetoxin-3 in CD-1 mice
    Janet M Benson
    Lovelace Respiratory Research Institute, 2425 Ridgecrest Dr SE, Albuquerque NM 87108, USA
    Toxicon 48:1018-26. 2006
    ..The consequences of these findings for pregnant women exposed to brevetoxins by inhalation or ingestion remain to be determined...
  7. doi request reprint Uptake, tissue distribution, and excretion of 14C-sulfur mustard vapor following inhalation in F344 rats and cutaneous exposure in hairless guinea pigs
    Janet M Benson
    CounterAct Research Center of Excellence, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA
    J Toxicol Environ Health A 74:875-85. 2011
    ..Urine was the primary route of excretion for both species. Results indicate inhaled SM is rapidly absorbed from the lung and distributed throughout the body while there is limited systemic distribution following cutaneous exposure...
  8. pmc Inhalation toxicity of brevetoxin 3 in rats exposed for twenty-two days
    Janet M Benson
    Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA
    Environ Health Perspect 113:626-31. 2005
    ..Results indicate that the immune system is the primary target for toxicity in rats after repeated inhalation exposure to relatively high concentrations of brevetoxins...
  9. pmc The toxicity of microcystin LR in mice following 7 days of inhalation exposure
    Janet M Benson
    Lovelace Respiratory Research Institute, 2425 Ridgecrest Dr SE, Albuquerque, NM 87108, USA
    Toxicon 45:691-8. 2005
    ..While these proteins have not been positively identified, they may be useful in the future as biomarkers of microcystin exposure in humans...
  10. ncbi request reprint Uptake, tissue distribution, and fate of inhaled carbon tetrachloride: comparison of rat, mouse, and hamster
    J M Benson
    Lovelace Respiratory Research Institute, PO Box 5890, Albuquerque, NM 87185 5890, USA
    Inhal Toxicol 13:207-17. 2001
    ..The results indicate that ranking of species sensitivity to the hepatotoxic effects of inhaled CCl(4) correlates with CE dose to liver and with the ability to metabolize CCl(4)...
  11. ncbi request reprint Particle clearance and histopathology in lungs of C3H/HeJ mice administered beryllium/copper alloy by intratracheal instillation
    J M Benson
    Lovelace Respiratory Research Institute, PO Box 5890, Albuquerque, NM 87185 5890, USA
    Inhal Toxicol 12:733-49. 2000
    ..The results of tissue analyses also indicate that, while the Cu component of the alloy clears the lung rapidly, Be is retained and may accumulate upon repeated exposure...
  12. ncbi request reprint The uptake, distribution, metabolism, and excretion of methyl tertiary-butyl ether inhaled alone and in combination with gasoline vapor
    Janet M Benson
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA
    J Toxicol Environ Health A 66:1029-52. 2003
    ....
  13. ncbi request reprint Dosimetry and acute toxicity of inhaled butadiene diepoxide in rats and mice
    R F Henderson
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87185, USA
    Toxicol Sci 51:146-52. 1999
    ..Therefore, the final design selected for the carcinogenesis study comprised exposing the rats and mice for 6 h/day, 5 days/week for 6 weeks to 0, 2.5, or 5.0 ppm BDO2...
  14. ncbi request reprint Carcinogenicity of inhaled butadiene diepoxide in female B6C3F1 mice and Sprague-Dawley rats
    R F Henderson
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87185 5890, USA
    Toxicol Sci 52:33-44. 1999
    ..The results indicate that the site of formation of the BDO2 is important for tumor induction...
  15. pmc Uptake, tissue distribution, and excretion of brevetoxin-3 administered to mice by intratracheal instillation
    Brad M Tibbetts
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA
    J Toxicol Environ Health A 69:1325-35. 2006
    ..These results are consistent with earlier reports of rapid absorption and widespread tissue distribution of brevetoxins in rats...
  16. pmc Particle size distribution and inhalation dose of shower water under selected operating conditions
    Yue Zhou
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA
    Inhal Toxicol 19:333-42. 2007
    ..Alveolar deposition was 6-10% and 0.9% assuming oral and nasal breathing, respectively. The consequences deposition of shower water droplets will depend on the nature and extent of any pollutants in the source water...
  17. ncbi request reprint Cardiovascular effects of inhaled diesel exhaust in spontaneously hypertensive rats
    Matthew J Campen
    Lovelace Respiratory Research Institute, National Environmental Respiratory Center, Albuquerque, NM, USA
    Cardiovasc Toxicol 3:353-61. 2003
    ..These results concur with previous reports suggesting that realistic exposure concentrations of air pollution affect the pacemaking system of rats...
  18. pmc Inhalation exposure systems for the development of rodent models of sulfur mustard-induced pulmonary injury
    Waylon M Weber
    Lovelace CounterACT Center of Excellence, Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA
    Toxicol Mech Methods 20:14-24. 2010
    ..Intratracheal inhalation of SM vapors at a concentration of 5400 mg x min/m(3) resulted in homogeneous lung injury with no nasal degeneration...
  19. ncbi request reprint Short-term inhalation of particulate transition metals has little effect on the electrocardiograms of dogs having preexisting cardiac abnormalities
    B A Muggenburg
    Lovelace Respiratory Research Institute, 2425 Ridgecrest Dr SE, Albuquerque, NM 87108, USA
    Inhal Toxicol 15:357-71. 2003
    ....
  20. pmc Cochlear function in mice following inhalation of brevetoxin-3
    Janet M Benson
    Lovelace Respiratory Research Institute, Albuquerque, NM, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 191:619-26. 2005
    ..Mice exposed only once for 2 h did not exhibit any notable cochlear effects. Similarly, mice exposed two times, for a cumulative dose of 6 h, exhibited essentially no change in DPOAE levels...
  21. ncbi request reprint A biphasic response to silica: I. Immunostimulation is restricted to the early stage of silicosis in lewis rats
    Raymond J Langley
    Immunology Program, Lovelace Respiratory Research Institute, 2425 Ridgecrest Dr SE, Albuquerque, NM 87108, USA
    Am J Respir Cell Mol Biol 30:823-9. 2004
    ..Thus, in the early stages of silicosis, silica activates the immune system; however, the progression of lung granulomas does not depend on a continually activated adaptive immune system...
  22. doi request reprint A review of whole animal bioassays of the carcinogenic potential of naphthalene
    D Warner North
    NorthWorks, Inc, 1002 Misty Lane, Belmont, CA 94002 3651, USA
    Regul Toxicol Pharmacol 51:S6-14. 2008
    ....
  23. pmc Brevetoxin-induced neural insult in the retrosplenial cortex of mouse brain
    Xiuzhen Yan
    Department of Physiology and Pharmacology, University of Georgia Athens, Georgia, USA
    Inhal Toxicol 18:1109-16. 2006
    ..These results suggest that subacute exposure to PbTx-3 for 2 days is sufficient to induce neuronal degeneration in a discrete region of the mouse cerebral cortex...
  24. doi request reprint Naphthalene metabolism in relation to target tissue anatomy, physiology, cytotoxicity and tumorigenic mechanism of action
    Kenneth T Bogen
    Exponent Health and Environmental, 500 12th Street, Suite 220, Oakland, CA 94607, USA
    Regul Toxicol Pharmacol 51:S27-36. 2008
    ....