Li-Ru Zhao

Summary

Affiliation: Louisiana State University Health Sciences Center
Country: USA

Publications

  1. pmc The role of stem cell factor and granulocyte-colony stimulating factor in treatment of stroke
    Li R Zhao
    Department of Neurology, Louisiana State University Health Sciences Center Shreveport, 1501 Kings Highway, Shreveport, Louisiana 71130, USA
    Recent Pat CNS Drug Discov 8:2-12. 2013
  2. pmc The combination of stem cell factor and granulocyte-colony stimulating factor for chronic stroke treatment in aged animals
    Chun Shu Piao
    Department of Neurology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA, 71130, USA
    Exp Transl Stroke Med 4:25. 2012
  3. pmc Stem cell factor and granulocyte colony-stimulating factor reduce β-amyloid deposits in the brains of APP/PS1 transgenic mice
    Bin Li
    Department of Neurology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA
    Alzheimers Res Ther 3:8. 2011
  4. ncbi request reprint Beneficial effects of hematopoietic growth factor therapy in chronic ischemic stroke in rats
    Li Ru Zhao
    Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Ill, USA
    Stroke 38:2804-11. 2007
  5. ncbi request reprint Multiphoton microscope imaging: the behavior of neural progenitor cells in the rostral migratory stream
    Li Ru Zhao
    Department of Neurology, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Chicago, IL 60611, USA
    Neurosci Lett 425:83-8. 2007
  6. ncbi request reprint Synthetic fibronectin peptide exerts neuroprotective effects on transient focal brain ischemia in rats
    Li Ru Zhao
    Department of Neurosurgery, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Brain Res 1054:1-8. 2005
  7. pmc Hematopoietic growth factors pass through the blood-brain barrier in intact rats
    Li Ru Zhao
    Department of Neurology, Northwestern University, Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Exp Neurol 204:569-73. 2007
  8. ncbi request reprint Brain repair by hematopoietic growth factors in a rat model of stroke
    Li Ru Zhao
    Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
    Stroke 38:2584-91. 2007
  9. pmc Dual function of Sox1 in telencephalic progenitor cells
    Lixin Kan
    Department of Neurology, Northwestern University Feinberg School of Medicine, 303 E Chicago Ave, Ward 10 233, Chicago, IL 60611 3008, USA
    Dev Biol 310:85-98. 2007
  10. doi request reprint Brain self-protection: the role of endogenous neural progenitor cells in adult brain after cerebral cortical ischemia
    Bin Li
    Department of Neurology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA
    Brain Res 1327:91-102. 2010

Collaborators

Detail Information

Publications16

  1. pmc The role of stem cell factor and granulocyte-colony stimulating factor in treatment of stroke
    Li R Zhao
    Department of Neurology, Louisiana State University Health Sciences Center Shreveport, 1501 Kings Highway, Shreveport, Louisiana 71130, USA
    Recent Pat CNS Drug Discov 8:2-12. 2013
    ..These findings would assist in developing new treatment for stroke. The article presents some promising patents on role of stem cell factor and granulocyte-colony stimulating factor in treatment of stroke...
  2. pmc The combination of stem cell factor and granulocyte-colony stimulating factor for chronic stroke treatment in aged animals
    Chun Shu Piao
    Department of Neurology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA, 71130, USA
    Exp Transl Stroke Med 4:25. 2012
    ..abstract:..
  3. pmc Stem cell factor and granulocyte colony-stimulating factor reduce β-amyloid deposits in the brains of APP/PS1 transgenic mice
    Bin Li
    Department of Neurology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA
    Alzheimers Res Ther 3:8. 2011
    ..The purpose of the present study is to determine whether SCF+G-CSF can reduce the burden of β-amyloid deposits in a mouse model of AD...
  4. ncbi request reprint Beneficial effects of hematopoietic growth factor therapy in chronic ischemic stroke in rats
    Li Ru Zhao
    Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Ill, USA
    Stroke 38:2804-11. 2007
    ..We have previously observed that SCF and G-CSF have neuroprotective and functional effects on acute brain ischemia. In the present study, the beneficial effects of SCF and G-CSF on chronic brain ischemia were determined...
  5. ncbi request reprint Multiphoton microscope imaging: the behavior of neural progenitor cells in the rostral migratory stream
    Li Ru Zhao
    Department of Neurology, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Chicago, IL 60611, USA
    Neurosci Lett 425:83-8. 2007
    ..Cell-cell contacts and microenvironmental changes influence NPC behavior in the RMS. This study may provide insights to help in understanding NPC biology...
  6. ncbi request reprint Synthetic fibronectin peptide exerts neuroprotective effects on transient focal brain ischemia in rats
    Li Ru Zhao
    Department of Neurosurgery, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Brain Res 1054:1-8. 2005
    ..These data indicate that the peptide PRARIY exerts its neuroprotective effects via supporting neural cell survival rather than anti-leukocyte recruitment following brain ischemia/reperfusion injury...
  7. pmc Hematopoietic growth factors pass through the blood-brain barrier in intact rats
    Li Ru Zhao
    Department of Neurology, Northwestern University, Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Exp Neurol 204:569-73. 2007
    ..This observation will help in further exploring the physiological role of peripheral SCF and G-CSF in the brain and therapeutic possibility to chronic stroke...
  8. ncbi request reprint Brain repair by hematopoietic growth factors in a rat model of stroke
    Li Ru Zhao
    Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
    Stroke 38:2584-91. 2007
    ..We determined whether receptors for SCF and G-CSF exist in the brain and whether exogenous SCF and G-CSF are beneficial to brain repair after brain ischemia...
  9. pmc Dual function of Sox1 in telencephalic progenitor cells
    Lixin Kan
    Department of Neurology, Northwestern University Feinberg School of Medicine, 303 E Chicago Ave, Ward 10 233, Chicago, IL 60611 3008, USA
    Dev Biol 310:85-98. 2007
    ....
  10. doi request reprint Brain self-protection: the role of endogenous neural progenitor cells in adult brain after cerebral cortical ischemia
    Bin Li
    Department of Neurology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA
    Brain Res 1327:91-102. 2010
    ..This study provides insights into the contribution of endogenous NSCs/NPCs to brain self-protection in adult brain after ischemia injury...
  11. ncbi request reprint Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats
    Li Ru Zhao
    Department of Neurosurgery, University of Minnesota, 55455, USA
    Exp Neurol 174:11-20. 2002
    ..The observed functional improvement might have been mediated by proteins secreted by transplanted hMSCs, which could have upregulated host brain plasticity in response to experimental stroke...
  12. ncbi request reprint Immunohistochemical identification of multipotent adult progenitor cells from human bone marrow after transplantation into the rat brain
    Li Ru Zhao
    Department of Neurosurgery, University of Minnesota Medical School, Lions Research Building, Room 421, 2001 Sixth Street S E, Minneapolis 55455, USA
    Brain Res Brain Res Protoc 11:38-45. 2003
    ..Here, we report a simple, effective and reproducible method of tissue preparation and fixation that results in the immunohistochemical labeling of transplanted and host cells...
  13. ncbi request reprint Sox1 acts through multiple independent pathways to promote neurogenesis
    Lixin Kan
    Department of Neurology, Northwestern University s Feinberg School of Medicine, Chicago, IL 60611 3008, USA
    Dev Biol 269:580-94. 2004
    ..These observations suggest that Sox1 works through multiple independent pathways to promote neuronal cell fate determination and differentiation...
  14. ncbi request reprint Tauroursodeoxycholic acid improves the survival and function of nigral transplants in a rat model of Parkinson's disease
    Wei Ming Duan
    Department of Neurosurgery, University of Minnesota Medical School, Minneapolis 55455, USA
    Cell Transplant 11:195-205. 2002
    ..These data demonstrate that pretreatment of the cell suspension with TUDCA can reduce apoptosis and increase the survival of grafted cells, resulting in an improvement of behavioral recovery...
  15. doi request reprint The role of stem cell factor and granulocyte-colony stimulating factor in brain repair during chronic stroke
    Chun Shu Piao
    Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
    J Cereb Blood Flow Metab 29:759-70. 2009
    ..These data suggest that SCF+G-CSF treatment can enhance repair of brain damage during chronic stroke by mobilizing BMSCs, and promoting the contribution of bone marrow-derived cells to angiogenesis and neurogenesis...
  16. ncbi request reprint Postischemic exercise attenuates whereas enriched environment has certain enhancing effects on lesion-induced subventricular zone activation in the adult rat
    Mila Komitova
    The Arvid Carlsson Institute at the Institute of Clinical Neuroscience, Medicinaregatan 11, Box 432, 405 30 Goteborg, Sweden
    Eur J Neurosci 21:2397-405. 2005
    ..It may be concluded that in contrast to enriched environment, exercise during the first postischemic week might be detrimental for regenerative processes initiated in the SVZ after stroke...