Masami Yoshimura

Summary

Affiliation: Louisiana State University
Country: USA

Publications

  1. ncbi request reprint Identification of ethanol responsive domains of adenylyl cyclase
    Masami Yoshimura
    Department of Pharmacology, University of Colorado Health Sciences Center, Aurora, CO, USA
    Alcohol Clin Exp Res 30:1824-32. 2006
  2. ncbi request reprint Ethanol-induced phosphorylation and potentiation of the activity of type 7 adenylyl cyclase. Involvement of protein kinase C delta
    Eric J Nelson
    Department of Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Biol Chem 278:4552-60. 2003
  3. pmc Neurotransplantation of stem cells genetically modified to express human dopamine transporter reduces alcohol consumption
    Tom N Grammatopoulos
    Department of Medicine, University of Colorado Denver, 12800 East 19th Avenue, Aurora, CO 80045, USA
    Stem Cell Res Ther 1:36. 2010
  4. ncbi request reprint A sex-specific role of type VII adenylyl cyclase in depression
    Lisa M Hines
    Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    J Neurosci 26:12609-19. 2006
  5. ncbi request reprint Isoform-specific enhancement of adenylyl cyclase activity by n-alkanols
    Jinghong Kou
    Department of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803, USA
    Alcohol Clin Exp Res 31:1467-72. 2007

Research Grants

  1. Action of ethanol on cyclic AMP signal transduction
    Masami Yoshimura; Fiscal Year: 2006
  2. Action of ethanol on cyclic AMP signal transduction
    Masami Yoshimura; Fiscal Year: 2010

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Identification of ethanol responsive domains of adenylyl cyclase
    Masami Yoshimura
    Department of Pharmacology, University of Colorado Health Sciences Center, Aurora, CO, USA
    Alcohol Clin Exp Res 30:1824-32. 2006
    ..The structural elements are designated as "ethanol responsive domains."..
  2. ncbi request reprint Ethanol-induced phosphorylation and potentiation of the activity of type 7 adenylyl cyclase. Involvement of protein kinase C delta
    Eric J Nelson
    Department of Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Biol Chem 278:4552-60. 2003
    ..Immunoprecipitation data indicated that PKCdelta could bind and directly phosphorylate AC7. The results indicate that the potentiation of AC7 activity by ethanol involves phosphorylation of AC7 that is mediated by PKCdelta...
  3. pmc Neurotransplantation of stem cells genetically modified to express human dopamine transporter reduces alcohol consumption
    Tom N Grammatopoulos
    Department of Medicine, University of Colorado Denver, 12800 East 19th Avenue, Aurora, CO 80045, USA
    Stem Cell Res Ther 1:36. 2010
    ..We reasoned that reducing extracellular DA levels, by engrafting into NAC DA-sequestering stem cells expressing hDAT, would alter alcohol intake...
  4. ncbi request reprint A sex-specific role of type VII adenylyl cyclase in depression
    Lisa M Hines
    Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    J Neurosci 26:12609-19. 2006
    ..Collectively, our results demonstrate a sex-specific influence of the AC7 gene on a heritable form of depressive illness...
  5. ncbi request reprint Isoform-specific enhancement of adenylyl cyclase activity by n-alkanols
    Jinghong Kou
    Department of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803, USA
    Alcohol Clin Exp Res 31:1467-72. 2007
    ..These findings suggest that the target of ethanol's action in the cAMP-generating system is AC. However, it is unknown if the action of ethanol is direct or indirect...

Research Grants9

  1. Action of ethanol on cyclic AMP signal transduction
    Masami Yoshimura; Fiscal Year: 2006
    ..The series of mutants of AC that will be generated and analyzed in the proposed study will be a valuable resource for future studies of the structure/function relationships of AC molecules. ..
  2. Action of ethanol on cyclic AMP signal transduction
    Masami Yoshimura; Fiscal Year: 2010
    ..This type of research is very important for rational drug development for the intervention of alcohol abuse and alcoholism. ..