Research Topics
Genomes and GenesSpecies | Eugene A WolteringSummaryAffiliation: Louisiana State University Health Sciences Center Country: USA Publications
| Collaborators
|
Detail Information
Publications
Effect of octreotide LAR dose and weight on octreotide blood levels in patients with neuroendocrine tumorsEugene A Woltering
Department of Surgery, Sections of Surgical Endocrinology and Oncology, Louisiana State University and The Veterans Administration Medical Center, New Orleans, LA 70012, USA
Pancreas 31:392-400. 2005..At identical monthly LAR doses, patients with higher weights will require more medication to achieve similar plasma octreotide levels than individuals with lower body weights...- Validation of serum versus plasma measurements of chromogranin a levels in patients with carcinoid tumors: lack of correlation between absolute chromogranin a levels and symptom frequencyEugene A Woltering
Section of Surgical Endocrinology, Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, LA, USA
Pancreas 33:250-4. 2006.... - Development of targeted somatostatin-based antiangiogenic therapy: a review and future perspectivesEugene A Woltering
Louisiana State University Health Sciences Center, Department of Surgery, LSUHSC Stanley S Scott Cancer Center, LSUHSC Neuroscience Center of Excellence, and the Veterans Affairs Medical Center, New Orleans, Louisiana 70112, USA
Cancer Biother Radiopharm 18:601-9. 2003..This manuscript reviews the development of somatostatin analogs as antiangiogenics in both their unlabeled and radiolabeled forms and postulates on future developments in this field... 
Development of a novel in vitro human tissue-based angiogenesis assay to evaluate the effect of antiangiogenic drugsEugene A Woltering
Department of Surgery, Section of Surgical Endocrinology, Louisiana State University Health Sciences Center, 1542 Tulane Avenue, New Orleans, LA 70112, USA
Ann Surg 237:790-8; discussion 798-800. 2003..To describe a novel in vitro human tissue-based angiogenic model that can predict an individual tumor's response to antiangiogenic drugs...- Clinical value of monitoring plasma octreotide levels during chronic octreotide long-acting repeatable therapy in carcinoid patientsEugene A Woltering
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, LA, USA
Pancreas 37:94-100. 2008..However, plasma octreotide levels have decreased over time in patients receiving these doses of LAR... - A prospective trial on the effect of body mass index and sex on plasma octreotide levels in patients undergoing long-term octreotide LAR therapySaju Joseph
Sections of Surgical Endocrinology and Hepatobiliary Surgery, Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, LA, USA
Pancreas 39:964-6. 2010..Previous work has shown that body weight and monthly LAR dose will significantly affect circulating plasma octreotide levels in patients undergoing therapy... 
Neurokinin A levels predict survival in patients with stage IV well differentiated small bowel neuroendocrine neoplasmsAnne E Diebold
Department of Surgery, Section of Surgical Endocrinology, The Louisiana State University Health Sciences Center, New Orleans, LA, USA
Surgery 152:1172-6. 2012..We hypothesized that American patients with persistently elevated plasma neurokinin A levels (>50 pg/mL) will also have a poor short-term survival...- Cervical and upper mediastinal lymph node metastasis from gastrointestinal and pancreatic neuroendocrine tumors: true incidence and managementYi Zarn Wang
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, LA, USA
J Am Coll Surg 214:1017-22. 2012..Historically, cervical nodes have been regarded as asymptomatic and ignored. We hypothesized that these lesions have clinical implications and should be removed surgically... - A phase I/II trial of 125I methylene blue for one-stage sentinel lymph node biopsyJason David Cundiff
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, USA
Ann Surg 245:290-6. 2007..To avoid these problems, we developed a novel radiolabeled blue dye that can be injected intraoperatively... - A novel assay to assess the effectiveness of antiangiogenic drugs in human breast cancerJohn M Lyons
Department of Surgery, Sections of Surgical Oncology and Surgical Endocrinology, Louisiana State University Health Sciences Center, Kenner, LA 70065, USA
Ann Surg Oncol 15:3407-14. 2008..We used a fibrin-thrombin clot-based angiogenesis model to evaluate the angiogenic response of human breast cancer to various cytotoxic agents commonly used in its treatment... - Neuroendocrine tumors: current recommendations for diagnosis and surgical managementSaju Joseph
Section of Endocrine Surgery, Department of Surgery, Louisiana State University Health Sciences Center, 200 West Esplanade Avenue, Suite 200, Kenner, LA 70065, USA
Endocrinol Metab Clin North Am 40:205-31, x. 2011.... - A study of pipeline drugs in neuroendocrine tumorsCatherine T Anthony
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
J Gastrointest Cancer 43:296-304. 2012..We tested a series of investigational agents to determine their ability to inhibit angiogenesis in our in vitro human angiogenesis model... - Effect of human Angiostatin protein on human angiogenesis in vitroSung Pil Jung
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
Angiogenesis 6:233-40. 2003.... - In vitro modeling of the clinical interactions between octreotide and 111In-pentetreotide: is there evidence of somatostatin receptor downregulation?Susan H Gunn
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
J Nucl Med 47:354-9. 2006.... - An extended phase II trial of iodine-125 methylene blue for sentinel lymph node identification in women with breast cancerWilliam W Harkrider
Louisiana State University Health Sciences Center, University Medical Center, Lafayette, LA, USA
J Am Coll Surg 216:599-605; discussion 605-6. 2013..The aim of this study was to determine if an intraoperative injection of iodine-125-labeled methylene blue ((125)I-MB) is a sensitive and effective method for detecting SLNs in women with breast cancer... - A prospective evaluation of the effect of chronic proton pump inhibitor use on plasma biomarker levels in humansDaniel Raines
Section of Gastroenterology, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, USA
Pancreas 41:508-11. 2012..Pancreastatin, a fragment of CGA, is also commonly used to diagnose and follow NETs. We hypothesized that chronic PPI use would increase circulating plasma gastrin, CGA, and pancreastatin levels... - The effect of AlloDerm on the initiation and growth of human neovesselsSean R Weiss
Department of Otorhinolaryngology Head and Neck Surgery, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
Laryngoscope 120:443-9. 2010..We hypothesized that AlloDerm would enhance angiogenesis and might be altered with autologous blood products to enhance initiation of the angiogenic response... - Inhibition of angiogenic initiation and disruption of newly established human vascular networks by juice from Morinda citrifolia (noni)Conrad A Hornick
Department of Physiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
Angiogenesis 6:143-9. 2003..In tumor explants which did show capillary sprouting, the vessels rapidly degenerated (2-3 days) in those exposed to media supplemented with 10% noni... - Do primary neuroendocrine tumors and metastasis have the same characteristics?Erika B Lindholm
Louisiana State University Health Sciences Center, Department of Surgery, Section of Surgical Endocrinology, New Orleans, Louisiana, USA
J Surg Res 174:200-6. 2012..We also hypothesized that limited tumor sampling could lead to erroneous assumptions about the tumor's histologic characteristics and clinical behavior... - Effect of human recombinant Endostatin protein on human angiogenesisSung P Jung
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
Angiogenesis 5:111-8. 2002..Human endostatin can inhibit the initiation of a human angiogenic response and inhibit the subsequent proliferation of human neovessels when used at high doses in a continuous exposure model... - Metronomic dosing enhances the anti-angiogenic effect of epothilone BMark W Stalder
Department of Surgery, Section of Endocrine Surgery, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70006, USA
J Surg Res 169:247-56. 2011..We hypothesized that epothilone B would be an effective anti-angiogenic agent when administered at very low doses over an extended period of time... - Lymphatic mapping helps to define resection margins for midgut carcinoidsYi Zarn Wang
Louisiana State University Health Sciences Center, Department of Surgery, Section of Surgical Oncology and Endocrine Surgery, New Orleans, LA, USA
Surgery 146:993-7. 2009..We hypothesized that altered lymphatic drainage makes traditional determination of resection margins inadequate... - Percutaneous localisation of pulmonary nodules prior to video-assisted thoracoscopic surgery using methylene blue and TC-99Yi Zarn Wang
Louisiana State University, Department of Surgery, New Orleans, LA 70112, USA
Eur J Cardiothorac Surg 37:237-8. 2010..This modified dual agent's preoperative localisation is logical, practical and easy to be adopted into the clinical setting for surgeons who choose to use the VATS technique in addressing these lung nodules... - The effect of drug dose and drug exposure time on the binding, internalization, and cytotoxicity of radiolabeled somatostatin analogsCatherine T Anthony
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans 70112, USA
J Surg Res 119:1-13. 2004..CONCLUSION: Both drug exposure time and drug concentration contribute to cell binding and cytotoxicity in this model and their relative contributions are inversely related... - The role of angiogenesis in neuroendocrine tumorsJohn Lyons
Department of Surgery, Louisiana State University, Health Sciences Center, New Orleans, LA 70112, USA
Endocrinol Metab Clin North Am 39:839-52. 2010..This article describes the evolution of methods to assess in vitro angiogenesis in neuroendocrine tumors and describes some of the clinical data... - In vitro chemoresistance testing in well-differentiated carcinoid tumorsJohn M Lyons
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
Ann Surg Oncol 16:649-55. 2009..We hypothesized that tumor specimens from well-differentiated carcinoid tumors would be highly resistant to the effects of chemotherapy when tested against a variety of antineoplastic agents in vitro... - Development of a human cardiac tissue-based angiogenesis modelJames M Lewis
Department of Surgery Sections of Surgical Endocrinology, Louisiana State University Health Sciences Center (LSUHSC, New Orleans, Louisiana 70112, USA
J Surg Res 135:34-7. 2006..This may allow the development of patient-specific therapies designed to enhance revascularization or repair of injured cardiac muscle... - Development of 125I-methylene blue for sentinel lymph node biopsyShawn J Stafford
Department of Surgery, The Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
J Surg Oncol 94:293-7. 2006.... - Resolution of pulsatile tinnitus following an upper mediastinal lymph node resectionYi Zarn Wang
Ochsner Medical Center Kenner, Kenner, LA 70065, USA
South Med J 103:374-7. 2010..We believe a careful search for nodal metastases compressing vascular structures in such patients is warranted as debilitating pulsatile tinnitus may be cured by a simple surgical procedure... - A single fasting plasma 5-HIAA value correlates with 24-hour urinary 5-HIAA values and other biomarkers in midgut neuroendocrine tumors (NETs)Maria R Tellez
Inter Science Institute, Inglewood, CA, USA
Pancreas 42:405-10. 2013..5-Hydroxyindoleacetic acid (5-HIAA) is used for the evaluation of neuroendocrine tumors (NETs) but currently requires a 24-hour urine collection... - The NANETS consensus guideline for the diagnosis and management of neuroendocrine tumors: well-differentiated neuroendocrine tumors of the Jejunum, Ileum, Appendix, and CecumJ Philip Boudreaux
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, LA, USA
Pancreas 39:753-66. 2010..Further studies of novel approaches such as peptide receptor radiotherapy are also warranted... - Indium-111-pentetreotide prolongs survival in gastroenteropancreatic malignanciesLowell B Anthony
Louisiana State University Medical Center, Department of Medicine, the Louisiana State University Health Sciences Center (LSUHSC, Stanley S. Scott Cancer Center, New Orleans, LA 70112, USA
Semin Nucl Med 32:123-32. 2002..The maximal tolerated dose of (111)In-pentetreotide and the optimal dosing schedules remain under investigation... - Sentinel nodal assessment in patients with carcinoma of the lungFrank E Schmidt
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans 70112, USA
Ann Thorac Surg 74:870-4; discussion 874-5. 2002..This study tested whether injection of isosulfan blue and technetium-99 could identify mediastinal sentinel nodes in patients with lung carcinoma and determine whether sentinel node histology predicts distal nodal metastases... - Role of somatostatin analogs in the clinical management of non-neuroendocrine solid tumorsLarry K Kvols
Inter Disciplinary Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
Anticancer Drugs 17:601-8. 2006.... - A new in vitro assay for human tumor angiogenesis: three-dimensional human tumor angiogenesis assaySeza A Gulec
John Wayne Cancer Institute, Santa Monica, California, USA
Ann Surg Oncol 11:99-104. 2004..CONCLUSIONS: This assay may allow functional assessment of the angiogenic potential of human tumors and simultaneous evaluation of a therapeutic agent's antitumor and antiangiogenic effects by virtue of its dual-compartmental structure... - Gamma probe-guided lymph node dissection ('gamma picking') in differentiated thyroid carcinomaSeza A Gulec
John Wayne Cancer Institute, Santa Monica, California 90404, USA
Clin Nucl Med 27:859-61. 2002..6 cm. Two of the four hot spots proved to be metastatic foci in small lymph nodes measuring less than 0.5 cm. The other two hot spots were thyroid remnants with no associated nodal tissue... - Gallic acid is partially responsible for the antiangiogenic activities of Rubus leaf extractZhijun Liu
School of Renewable Natural Resources, LSU Agricultural Center, Louisiana State University, Baton Rouge, LA 70803, USA
Phytother Res 20:806-13. 2006..1% w/w caused a 41% inhibition of angiogenesis compared with saline injected controls. These preliminary results warrant further bioassay directed identification of other responsible compounds... - Black raspberry extract and fractions contain angiogenesis inhibitorsZhijun Liu
Louisiana State University Agricultural Center, 227 Renewable Natural Resources Building, Baton Rouge, Louisiana 70803, USA
J Agric Food Chem 53:3909-15. 2005..These extracts contain multiple active ingredients that may be additive or synergistic in their antiangiogenic effects. These observations warrant further investigations in animals and human trials... - A multi-tyrosinated sst1/2 receptor preferring somatostatin agonist inhibits reflex and immune-mediated secretion in the guinea pig colonHelen J Cooke
Department of Neuroscience, The Ohio State University, Columbus, OH 43210, USA
Regul Pept 114:51-60. 2003..The results suggest that WOC 3B, a somatostatin analogue containing three tyrosine residues, has anti-secretory effects due to activation of somatostatin sst1 and sst2 receptors on enteric neurons... - An assay to measure angiogenesis in human fat tissueFrank L Greenway
Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA
Obes Surg 17:510-5. 2007..Inhibition of angiogenesis reverses rodent obesity. A validated assay in human fat tissue is needed to study the role of angiogenesis in human obesity...