Research Topics
Genomes and Genes | Kelly TatchellSummaryAffiliation: Louisiana State University Health Sciences Center Country: USA Publications
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Detail Information
Publications
Temperature-sensitive ipl1-2/Aurora B mutation is suppressed by mutations in TOR complex 1 via the Glc7/PP1 phosphataseKelly Tatchell
Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
Proc Natl Acad Sci U S A 108:3994-9. 2011..Together, our results suggest that TORC1 positively regulates the Glc7 activity that opposes Ipl1 and provide a mechanism to tie nutritional status with mitotic regulation...- Protein phosphatase type 1 directs chitin synthesis at the bud neck in Saccharomyces cerevisiaeJennifer R Larson
Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
Mol Biol Cell 19:3040-51. 2008..These results suggest that the essential role of Bni4 is to target Glc7 to the neck and activate it toward substrates necessary for CSIII recruitment and synthesis of chitin at the bud neck... - Ypi1, a positive regulator of nuclear protein phosphatase type 1 activity in Saccharomyces cerevisiaeJennifer P Bharucha
Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
Mol Biol Cell 19:1032-45. 2008..These results, together with genetic interactions among YPI1, GLC7, and SDS22 mutants, indicate that Ypi1 and Sds22 are positive regulators of the nuclear Glc7 activity that is required for mitosis... - The Set1 methyltransferase opposes Ipl1 aurora kinase functions in chromosome segregationKe Zhang
Program in Genes and Development, Department of Biochemistry and Molecular Biology, M D Anderson Cancer Center, University of Texas, Houston, Texas 77030, USA
Cell 122:723-34. 2005..Moreover, our findings suggest that antagonism between lysine methylation and serine phosphorylation is a fundamental mechanism for controlling protein function... - Changes in Bni4 localization induced by cell stress in Saccharomyces cerevisiaeJennifer R Larson
Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
J Cell Sci 123:1050-9. 2010.... - Saccharomyces cerevisiae Afr1 protein is a protein phosphatase 1/Glc7-targeting subunit that regulates the septin cytoskeleton during matingJennifer P Bharucha
Department of Biochemistry and Molecular Biology, 1501 Kings Highway, LSU Health Sciences Center, Shreveport LA 71130, USA
Eukaryot Cell 7:1246-55. 2008..These results demonstrate a previously unknown role for Afr1 in targeting Glc7 to mating projections and in regulating the septin architecture during mating... - Role of the septin ring in the asymmetric localization of proteins at the mother-bud neck in Saccharomyces cerevisiaeLukasz Kozubowski
Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
Mol Biol Cell 16:3455-66. 2005..These observations provide clues to the mechanisms for the asymmetric localization of septin-associated proteins... - Novel suppressors of alpha-synuclein toxicity identified using yeastJun Liang
Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130 3932, USA
Hum Mol Genet 17:3784-95. 2008..Our interpretation is that Ent3p mediates the transport of alpha-syn to the vacuole for proteolytic degradation. A similar clathrin adaptor protein, epsinR, exists in humans... - Mycobacterium tuberculosis Ku can bind to nuclear DNA damage and sensitize mammalian cells to bleomycin sulfateReneau Castore
Department of Molecular and Cellular Physiology, LSUHSC S, Shreveport, LA, USA
Mutagenesis 26:795-803. 2011..This study indicates that blocking or decreasing the binding of human Ku to DSBs could be a method for enhancing existing cancer treatments... - A Bni4-Glc7 phosphatase complex that recruits chitin synthase to the site of bud emergenceLukasz Kozubowski
Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
Mol Biol Cell 14:26-39. 2003..Together, these results indicate that the formation of the Bni4-Glc7 complex is required for localization to the site of bud emergence and for subsequent targeting of chitin synthase... - Protein phosphatase type 1 regulates ion homeostasis in Saccharomyces cerevisiaeTara Williams-Hart
Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
Genetics 160:1423-37. 2002..Together, these results indicate that Glc7 regulates ion homeostasis by controlling ion transport and/or plasma membrane potential, a new role for Glc7 in budding yeast... 
Site-specific loss of acetylation upon phosphorylation of histone H3Diane G Edmondson
Department of Biochemistry and Molecular Biology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
J Biol Chem 277:29496-502. 2002....- Suppressors of ipl1-2 in components of a Glc7 phosphatase complex, Cdc48 AAA ATPase, TORC1, and the kinetochoreLucy C Robinson
Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
G3 (Bethesda) 2:1687-701. 2012..The slow growth and cell cycle delay of ndc80-K204E cells are partially alleviated by the ipl1-2 mutation. These data provide biological confirmation of a biochemically based model for the effect of phosphorylation on Ndc80 function... - Use of green fluorescent protein in living yeast cellsKelly Tatchell
Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
Methods Enzymol 351:661-83. 2002