Kelly Tatchell

Summary

Affiliation: Louisiana State University Health Sciences Center
Country: USA

Publications

  1. pmc Temperature-sensitive ipl1-2/Aurora B mutation is suppressed by mutations in TOR complex 1 via the Glc7/PP1 phosphatase
    Kelly Tatchell
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    Proc Natl Acad Sci U S A 108:3994-9. 2011
  2. pmc Suppressors of ipl1-2 in components of a Glc7 phosphatase complex, Cdc48 AAA ATPase, TORC1, and the kinetochore
    Lucy C Robinson
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
    G3 (Bethesda) 2:1687-701. 2012
  3. pmc Protein phosphatase type 1 directs chitin synthesis at the bud neck in Saccharomyces cerevisiae
    Jennifer R Larson
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    Mol Biol Cell 19:3040-51. 2008
  4. pmc The Set1 methyltransferase opposes Ipl1 aurora kinase functions in chromosome segregation
    Ke Zhang
    Program in Genes and Development, Department of Biochemistry and Molecular Biology, M D Anderson Cancer Center, University of Texas, Houston, Texas 77030, USA
    Cell 122:723-34. 2005
  5. pmc Ypi1, a positive regulator of nuclear protein phosphatase type 1 activity in Saccharomyces cerevisiae
    Jennifer P Bharucha
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    Mol Biol Cell 19:1032-45. 2008
  6. pmc Saccharomyces cerevisiae Afr1 protein is a protein phosphatase 1/Glc7-targeting subunit that regulates the septin cytoskeleton during mating
    Jennifer P Bharucha
    Department of Biochemistry and Molecular Biology, 1501 Kings Highway, LSU Health Sciences Center, Shreveport LA 71130, USA
    Eukaryot Cell 7:1246-55. 2008
  7. pmc Changes in Bni4 localization induced by cell stress in Saccharomyces cerevisiae
    Jennifer R Larson
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    J Cell Sci 123:1050-9. 2010
  8. pmc Role of the septin ring in the asymmetric localization of proteins at the mother-bud neck in Saccharomyces cerevisiae
    Lukasz Kozubowski
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    Mol Biol Cell 16:3455-66. 2005
  9. pmc Novel suppressors of alpha-synuclein toxicity identified using yeast
    Jun Liang
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130 3932, USA
    Hum Mol Genet 17:3784-95. 2008
  10. pmc Mycobacterium tuberculosis Ku can bind to nuclear DNA damage and sensitize mammalian cells to bleomycin sulfate
    Reneau Castore
    Department of Molecular and Cellular Physiology, LSUHSC S, Shreveport, LA, USA
    Mutagenesis 26:795-803. 2011

Collaborators

  • Lukasz Kozubowski
  • Lynn Harrison
  • Ryuji Kobayashi
  • Ke Zhang
  • Jennifer R Larson
  • Jennifer P Bharucha
  • Lucy C Robinson
  • Reneau Castore
  • Tara Williams-Hart
  • Jun Liang
  • Diane G Edmondson
  • Evan P Boswell
  • Lina Brou
  • Joshua Phillips
  • Jingxin Sun
  • Cailing Zeng
  • Runhua Shi
  • Kyung Jong Lee
  • David J Chen
  • Cameron Hughes
  • Austin DeBeaux
  • Shih Ya Wang
  • Lisa K Daves
  • Charles J Richardson
  • Stephan N Witt
  • Shaoxiao Wang
  • Todd R Flower
  • James B Konopka
  • Segalit M Rivera
  • Shantelle Ceaser
  • Cheryl Clark-Dixon
  • Joanna Salamon
  • Lu Gao
  • Richard Zweig
  • Judith K Davie
  • Xiaolin Wu
  • Banafsheh Mirnikjoo
  • Jenny Zhou
  • Sharon Y R Dent

Detail Information

Publications14

  1. pmc Temperature-sensitive ipl1-2/Aurora B mutation is suppressed by mutations in TOR complex 1 via the Glc7/PP1 phosphatase
    Kelly Tatchell
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    Proc Natl Acad Sci U S A 108:3994-9. 2011
    ..Together, our results suggest that TORC1 positively regulates the Glc7 activity that opposes Ipl1 and provide a mechanism to tie nutritional status with mitotic regulation...
  2. pmc Suppressors of ipl1-2 in components of a Glc7 phosphatase complex, Cdc48 AAA ATPase, TORC1, and the kinetochore
    Lucy C Robinson
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
    G3 (Bethesda) 2:1687-701. 2012
    ..The slow growth and cell cycle delay of ndc80-K204E cells are partially alleviated by the ipl1-2 mutation. These data provide biological confirmation of a biochemically based model for the effect of phosphorylation on Ndc80 function...
  3. pmc Protein phosphatase type 1 directs chitin synthesis at the bud neck in Saccharomyces cerevisiae
    Jennifer R Larson
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    Mol Biol Cell 19:3040-51. 2008
    ..These results suggest that the essential role of Bni4 is to target Glc7 to the neck and activate it toward substrates necessary for CSIII recruitment and synthesis of chitin at the bud neck...
  4. pmc The Set1 methyltransferase opposes Ipl1 aurora kinase functions in chromosome segregation
    Ke Zhang
    Program in Genes and Development, Department of Biochemistry and Molecular Biology, M D Anderson Cancer Center, University of Texas, Houston, Texas 77030, USA
    Cell 122:723-34. 2005
    ..Moreover, our findings suggest that antagonism between lysine methylation and serine phosphorylation is a fundamental mechanism for controlling protein function...
  5. pmc Ypi1, a positive regulator of nuclear protein phosphatase type 1 activity in Saccharomyces cerevisiae
    Jennifer P Bharucha
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    Mol Biol Cell 19:1032-45. 2008
    ..These results, together with genetic interactions among YPI1, GLC7, and SDS22 mutants, indicate that Ypi1 and Sds22 are positive regulators of the nuclear Glc7 activity that is required for mitosis...
  6. pmc Saccharomyces cerevisiae Afr1 protein is a protein phosphatase 1/Glc7-targeting subunit that regulates the septin cytoskeleton during mating
    Jennifer P Bharucha
    Department of Biochemistry and Molecular Biology, 1501 Kings Highway, LSU Health Sciences Center, Shreveport LA 71130, USA
    Eukaryot Cell 7:1246-55. 2008
    ..These results demonstrate a previously unknown role for Afr1 in targeting Glc7 to mating projections and in regulating the septin architecture during mating...
  7. pmc Changes in Bni4 localization induced by cell stress in Saccharomyces cerevisiae
    Jennifer R Larson
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    J Cell Sci 123:1050-9. 2010
    ....
  8. pmc Role of the septin ring in the asymmetric localization of proteins at the mother-bud neck in Saccharomyces cerevisiae
    Lukasz Kozubowski
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    Mol Biol Cell 16:3455-66. 2005
    ..These observations provide clues to the mechanisms for the asymmetric localization of septin-associated proteins...
  9. pmc Novel suppressors of alpha-synuclein toxicity identified using yeast
    Jun Liang
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130 3932, USA
    Hum Mol Genet 17:3784-95. 2008
    ..Our interpretation is that Ent3p mediates the transport of alpha-syn to the vacuole for proteolytic degradation. A similar clathrin adaptor protein, epsinR, exists in humans...
  10. pmc Mycobacterium tuberculosis Ku can bind to nuclear DNA damage and sensitize mammalian cells to bleomycin sulfate
    Reneau Castore
    Department of Molecular and Cellular Physiology, LSUHSC S, Shreveport, LA, USA
    Mutagenesis 26:795-803. 2011
    ..This study indicates that blocking or decreasing the binding of human Ku to DSBs could be a method for enhancing existing cancer treatments...
  11. pmc A Bni4-Glc7 phosphatase complex that recruits chitin synthase to the site of bud emergence
    Lukasz Kozubowski
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
    Mol Biol Cell 14:26-39. 2003
    ..Together, these results indicate that the formation of the Bni4-Glc7 complex is required for localization to the site of bud emergence and for subsequent targeting of chitin synthase...
  12. ncbi request reprint Site-specific loss of acetylation upon phosphorylation of histone H3
    Diane G Edmondson
    Department of Biochemistry and Molecular Biology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Biol Chem 277:29496-502. 2002
    ....
  13. pmc Protein phosphatase type 1 regulates ion homeostasis in Saccharomyces cerevisiae
    Tara Williams-Hart
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
    Genetics 160:1423-37. 2002
    ..Together, these results indicate that Glc7 regulates ion homeostasis by controlling ion transport and/or plasma membrane potential, a new role for Glc7 in budding yeast...
  14. ncbi request reprint Use of green fluorescent protein in living yeast cells
    Kelly Tatchell
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
    Methods Enzymol 351:661-83. 2002