Patrick M Smith

Summary

Affiliation: Louisiana State University Health Sciences Center
Country: USA

Publications

  1. pmc Expression of the full-length form of gp2 of equine herpesvirus 1 (EHV-1) completely restores respiratory virulence to the attenuated EHV-1 strain KyA in CBA mice
    Patrick M Smith
    Department of Microbiology and Immunology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    J Virol 79:5105-15. 2005
  2. ncbi request reprint Meningoencephalitis in mice infected with an equine herpesvirus 1 strain KyA recombinant expressing glycoprotein I and glycoprotein E
    Arthur R Frampton
    Center for Molecular and Tumor Virology, Louisiana State University Health Sciences Center, Shreveport 71130, USA
    Virus Genes 29:9-17. 2004
  3. ncbi request reprint Cytokine profiles and long-term virus-specific antibodies following immunization of CBA mice with equine herpesvirus 1 and viral glycoprotein D
    Yunfei Zhang
    Department of Microbiology and Immunology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130 3932, USA
    Viral Immunol 16:307-20. 2003
  4. ncbi request reprint In vitro and in vivo characterization of equine herpesvirus type 1 (EHV-1) mutants devoid of the viral chemokine-binding glycoprotein G (gG)
    Jens von Einem
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Virology 362:151-62. 2007
  5. ncbi request reprint Contribution of gene products encoded within the unique short segment of equine herpesvirus 1 to virulence in a murine model
    Arthur R Frampton
    Department of Microbiology and Immunology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130 3932, USA
    Virus Res 90:287-301. 2002
  6. pmc Transcriptome analysis reveals human cytomegalovirus reprograms monocyte differentiation toward an M1 macrophage
    Gary Chan
    Department of Microbiology and Immunology, Center for Molecular and Tumor Virology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    J Immunol 181:698-711. 2008

Collaborators

Detail Information

Publications6

  1. pmc Expression of the full-length form of gp2 of equine herpesvirus 1 (EHV-1) completely restores respiratory virulence to the attenuated EHV-1 strain KyA in CBA mice
    Patrick M Smith
    Department of Microbiology and Immunology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    J Virol 79:5105-15. 2005
    ....
  2. ncbi request reprint Meningoencephalitis in mice infected with an equine herpesvirus 1 strain KyA recombinant expressing glycoprotein I and glycoprotein E
    Arthur R Frampton
    Center for Molecular and Tumor Virology, Louisiana State University Health Sciences Center, Shreveport 71130, USA
    Virus Genes 29:9-17. 2004
    ..We propose that gI and gE are neurovirulence factors for EHV-1, and that the CBA mouse model can be extended to study neurologic sequelae resulting after EHV-1 infection...
  3. ncbi request reprint Cytokine profiles and long-term virus-specific antibodies following immunization of CBA mice with equine herpesvirus 1 and viral glycoprotein D
    Yunfei Zhang
    Department of Microbiology and Immunology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130 3932, USA
    Viral Immunol 16:307-20. 2003
    ..Overall, the data indicate that immunization with infectious KyA or rgD induces significant levels of cytokines, virus-specific ASC in the lungs and spleen, and long-term virus specific B-cell responses...
  4. ncbi request reprint In vitro and in vivo characterization of equine herpesvirus type 1 (EHV-1) mutants devoid of the viral chemokine-binding glycoprotein G (gG)
    Jens von Einem
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Virology 362:151-62. 2007
    ..Therefore we concluded that deletion of gG in EHV-1 seems to lead to an exacerbation of respiratory disease in the mouse...
  5. ncbi request reprint Contribution of gene products encoded within the unique short segment of equine herpesvirus 1 to virulence in a murine model
    Arthur R Frampton
    Department of Microbiology and Immunology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130 3932, USA
    Virus Res 90:287-301. 2002
    ..These findings show that gI, and/or gI and gE restore a virulent phenotype to the EHV-1 KyA strain, and indicate that virulence factors, in addition to gI and gE, contribute to the pathogenesis of the RacL11 strain...
  6. pmc Transcriptome analysis reveals human cytomegalovirus reprograms monocyte differentiation toward an M1 macrophage
    Gary Chan
    Department of Microbiology and Immunology, Center for Molecular and Tumor Virology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    J Immunol 181:698-711. 2008
    ..Overall, the results identify that the HCMV-infected monocyte transcriptome displayed a unique M1/M2 polarization signature that was skewed toward the classical M1 activation phenotype...