Ashok K Pullikuth

Summary

Affiliation: Louisiana State University Health Sciences Center
Country: USA

Publications

  1. pmc Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion
    Siyi Hu
    Stanley S Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Mol Cancer 9:30. 2010
  2. pmc Differential requirement for MEK Partner 1 in DU145 prostate cancer cell migration
    Electa R Park
    Department of Pharmacology, LSU Health Sciences Center New Orleans, LA, USA
    Cell Commun Signal 7:26. 2009
  3. pmc Extracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP
    Ashok K Pullikuth
    Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Mol Cell Biol 30:3233-48. 2010
  4. pmc Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective
    Ashok K Pullikuth
    Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Cell Signal 19:1621-32. 2007
  5. ncbi Molecular characterization of sodium/proton exchanger 3 (NHE3) from the yellow fever vector, Aedes aegypti
    Ashok K Pullikuth
    Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521 0146, USA
    J Exp Biol 209:3529-44. 2006
  6. ncbi NHE8 mediates amiloride-sensitive Na+/H+ exchange across mosquito Malpighian tubules and catalyzes Na+ and K+ transport in reconstituted proteoliposomes
    Wanyoike Kang'ethe
    Graduate Program in Environmental Toxicology, University of California, Riverside, California 92521, USA
    Am J Physiol Renal Physiol 292:F1501-12. 2007
  7. ncbi Phylogeny and cloning of ion transporters in mosquitoes
    Ashok K Pullikuth
    Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, USA
    J Exp Biol 206:3857-68. 2003
  8. doi ISG15 disrupts cytoskeletal architecture and promotes motility in human breast cancer cells
    Shyamal D Desai
    Department of Biochemistry and Molecular Biology, LSU Health Sciences Center School of Medicine, 1901 Perdido Street, New Orleans, LA 70112, USA
    Exp Biol Med (Maywood) 237:38-49. 2012
  9. ncbi In vivo membrane trafficking role for an insect N-ethylmaleimide-sensitive factor which is developmentally regulated in endocrine cells
    Ashok K Pullikuth
    Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, USA
    J Exp Biol 205:911-26. 2002
  10. pmc Trypanosomatid RACK1 orthologs show functional differences associated with translation despite similar roles in Leishmania pathogenesis
    Kohelia Choudhury
    Department of Microbiology Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
    PLoS ONE 6:e20710. 2011

Collaborators

  • Christopher D Deppmann
  • Jerome W Breslin
  • Shyamal D Desai
  • Ben L Kelly
  • Alejandra Bravo
  • Mario Soberon
  • Andrew D Catling
  • David J Mitchell
  • Kohelia Choudhury
  • Siyi Hu
  • Electa R Park
  • Wanyoike Kang'ethe
  • Sarjeet S Gill
  • Meibao Zhuang
  • Donald F Hunt
  • K Kevin Pfister
  • W Russell Smiley
  • Erin D Jeffery
  • Kiev R Blasier
  • Juyeon Park
  • Kevin W H Lo
  • Jeffrey Shabanowitz
  • Jonathan C Trinidad
  • Dong Suo
  • Mitchell W Ross
  • Ashok Aiyar
  • Daviel Cardenas
  • Nathalie Delorme
  • Shahriar Koochekpour
  • Tao Liu
  • Zhenzhen Liu
  • Jone Garai
  • Cruz Velasco-Gonzalez
  • Evangeline M Bailey
  • Donald E Mercante
  • Karlygash G Aimanova
  • Isabel Gomez
  • Daniela I Oltean

Detail Information

Publications13

  1. pmc Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion
    Siyi Hu
    Stanley S Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Mol Cancer 9:30. 2010
    ..PSAP is the lysosomal precursor of saposins, which serve as activators for lysosomal hydrolases involved in the degradation of ceramide (Cer) and other sphingolipids...
  2. pmc Differential requirement for MEK Partner 1 in DU145 prostate cancer cell migration
    Electa R Park
    Department of Pharmacology, LSU Health Sciences Center New Orleans, LA, USA
    Cell Commun Signal 7:26. 2009
    ..MP1 may function by regulating the stability or expression of paxillin, a key regulator of motility...
  3. pmc Extracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP
    Ashok K Pullikuth
    Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Mol Cell Biol 30:3233-48. 2010
    ..These observations reveal a novel role for ERK signaling in adhesion assembly in addition to its established role in adhesion disassembly...
  4. pmc Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective
    Ashok K Pullikuth
    Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Cell Signal 19:1621-32. 2007
    ..Here we review data supporting the view that localized ERK signaling mediated through recently identified scaffold proteins may regulate cell migration...
  5. ncbi Molecular characterization of sodium/proton exchanger 3 (NHE3) from the yellow fever vector, Aedes aegypti
    Ashok K Pullikuth
    Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521 0146, USA
    J Exp Biol 209:3529-44. 2006
    ....
  6. ncbi NHE8 mediates amiloride-sensitive Na+/H+ exchange across mosquito Malpighian tubules and catalyzes Na+ and K+ transport in reconstituted proteoliposomes
    Wanyoike Kang'ethe
    Graduate Program in Environmental Toxicology, University of California, Riverside, California 92521, USA
    Am J Physiol Renal Physiol 292:F1501-12. 2007
    ..We propose that AeNHE8 may be coupled to the inward H(+) gradient across the Malpighian tubules and plays a role in the extrusion of excess sodium and potassium while maintaining steady intracellular pH in the principal cells...
  7. ncbi Phylogeny and cloning of ion transporters in mosquitoes
    Ashok K Pullikuth
    Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, USA
    J Exp Biol 206:3857-68. 2003
    ..Ion transport mechanisms will be discussed from a comparative physiology perspective to gain appreciation of the exquisite mechanisms of mosquito ion regulation...
  8. doi ISG15 disrupts cytoskeletal architecture and promotes motility in human breast cancer cells
    Shyamal D Desai
    Department of Biochemistry and Molecular Biology, LSU Health Sciences Center School of Medicine, 1901 Perdido Street, New Orleans, LA 70112, USA
    Exp Biol Med (Maywood) 237:38-49. 2012
    ....
  9. ncbi In vivo membrane trafficking role for an insect N-ethylmaleimide-sensitive factor which is developmentally regulated in endocrine cells
    Ashok K Pullikuth
    Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, USA
    J Exp Biol 205:911-26. 2002
    ..This underscores the utility of our approach to delineate functional roles for proteins from systems that are not currently amenable to in vitro reconstitution...
  10. pmc Trypanosomatid RACK1 orthologs show functional differences associated with translation despite similar roles in Leishmania pathogenesis
    Kohelia Choudhury
    Department of Microbiology Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
    PLoS ONE 6:e20710. 2011
    ..While biochemically distinguishable, both LACK/LACK and LACK/TbRACK1 lines were more tolerant of elevated temperatures, resistant to translation inhibitors, and displayed robust pathogenesis in vivo, contrasting to LACK/- parasites...
  11. pmc Epidermal growth factor stimulates extracellular-signal regulated kinase phosphorylation of a novel site on cytoplasmic Dynein intermediate chain 2
    Ashok K Pullikuth
    Department of Pharmacology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Int J Mol Sci 14:3595-620. 2013
    ..These data suggest that ERK phosphorylation of IC-2 regulates dynein function through mechanisms other than its interaction with dynactin...
  12. pmc Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transport
    David J Mitchell
    Department of Cell Biology, University of Virginia, Charlottesville, VA 22908, USA
    J Neurosci 32:15495-510. 2012
    ..These results demonstrate that neurotrophin binding to Trk initiates the recruitment of cytoplasmic dynein to signaling endosomes through ERK1/2 phosphorylation of intermediate chains for their subsequent retrograde transport in axons...
  13. ncbi Heliothis virescens and Manduca sexta lipid rafts are involved in Cry1A toxin binding to the midgut epithelium and subsequent pore formation
    Meibao Zhuang
    Environmental Toxicology Graduate Program, Department of Cell Biology and Neuroscience, University of California, Riverside, California 92521, USA
    J Biol Chem 277:13863-72. 2002
    ..Our study strongly suggests that these microdomains might be involved in Cry1A toxin aggregation and pore formation...