William A Pryor

Summary

Affiliation: Louisiana State University
Country: USA

Publications

  1. ncbi request reprint Vitamin E and heart disease: basic science to clinical intervention trials
    W A Pryor
    The Biodynamics Institute, Louisiana State University, Baton Rouge 70803, USA
    Free Radic Biol Med 28:141-64. 2000
  2. ncbi request reprint Fractionation of aqueous cigarette tar extracts: fractions that contain the tar radical cause DNA damage
    W A Pryor
    Biodynamics Institute, 711 Choppin Hall, Louisiana State University, Baton Rouge, Louisiana 70803 1800, USA
    Chem Res Toxicol 11:441-8. 1998
  3. ncbi request reprint Free radical biology and medicine: it's a gas, man!
    William A Pryor
    Biodynamics Institute, Louisiana State University, Baton Rouge, LA 70803, USA
    Am J Physiol Regul Integr Comp Physiol 291:R491-511. 2006
  4. ncbi request reprint Role of free radicals in the toxicity of airborne fine particulate matter
    B Dellinger
    Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, USA
    Chem Res Toxicol 14:1371-7. 2001
  5. ncbi request reprint A new mechanism for the toxicity of ozone
    W A Pryor
    Biodynamics Institute, Louisiana State University, Baton Rouge 70803 1800, USA
    Toxicol Lett 82:287-93. 1995
  6. ncbi request reprint Quinoid redox cycling as a mechanism for sustained free radical generation by inhaled airborne particulate matter
    G L Squadrito
    Biodynamics Institute, Louisiana State University, Baton Rouge, LA 70803, USA
    Free Radic Biol Med 31:1132-8. 2001
  7. ncbi request reprint Detection of aldehydes in bronchoalveolar lavage of rats exposed to ozone
    W A Pryor
    Biodynamics Institute, Louisiana State University, Baton Rouge 70803 1800, USA
    Fundam Appl Toxicol 34:148-56. 1996
  8. ncbi request reprint Scavenging of peroxynitrite by a phenolic/peroxidase system prevents oxidative damage to DNA
    S C Grace
    Biodynamics Institute, Louisiana State University, Baton Rouge 70803 1800, USA
    FEBS Lett 426:24-8. 1998
  9. ncbi request reprint Overexpression of hMTH1 mRNA: a molecular marker of oxidative stress in lung cancer cells
    C H Kennedy
    Biodynamics Institute, Louisiana State University, Baton Rouge 70803, USA
    FEBS Lett 429:17-20. 1998
  10. ncbi request reprint Reaction of uric acid with peroxynitrite and implications for the mechanism of neuroprotection by uric acid
    G L Squadrito
    Biodynamics Institute, Louisiana State University, 711 Choppin Hall, Baton Rouge, Louisiana 70803 1800, USA
    Arch Biochem Biophys 376:333-7. 2000

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Vitamin E and heart disease: basic science to clinical intervention trials
    W A Pryor
    The Biodynamics Institute, Louisiana State University, Baton Rouge 70803, USA
    Free Radic Biol Med 28:141-64. 2000
    ..In view of the very low risk of reasonable supplementation with vitamin E, and the difficulty in obtaining more than about 30 IU/day from a balanced diet, some supplementation appears prudent now...
  2. ncbi request reprint Fractionation of aqueous cigarette tar extracts: fractions that contain the tar radical cause DNA damage
    W A Pryor
    Biodynamics Institute, 711 Choppin Hall, Louisiana State University, Baton Rouge, Louisiana 70803 1800, USA
    Chem Res Toxicol 11:441-8. 1998
    ..The tar radical associates with DNA, causes DNA damage, and very likely is involved in the toxicity associated with cigarette smoking...
  3. ncbi request reprint Free radical biology and medicine: it's a gas, man!
    William A Pryor
    Biodynamics Institute, Louisiana State University, Baton Rouge, LA 70803, USA
    Am J Physiol Regul Integr Comp Physiol 291:R491-511. 2006
    ..Such adaptive mechanisms are thought to be of evolutionary importance...
  4. ncbi request reprint Role of free radicals in the toxicity of airborne fine particulate matter
    B Dellinger
    Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, USA
    Chem Res Toxicol 14:1371-7. 2001
    ..PM2.5-mediated DNA damage was abolished by superoxide dismutase, catalase, and deferoxamine, implicating superoxide radical, hydrogen peroxide, and the hydroxyl radical in the reactions inducing DNA damage...
  5. ncbi request reprint A new mechanism for the toxicity of ozone
    W A Pryor
    Biodynamics Institute, Louisiana State University, Baton Rouge 70803 1800, USA
    Toxicol Lett 82:287-93. 1995
    ..Preliminary data show that individual LOP cause the activation of specific lipases, which trigger the release of endogenous mediators of inflammation...
  6. ncbi request reprint Quinoid redox cycling as a mechanism for sustained free radical generation by inhaled airborne particulate matter
    G L Squadrito
    Biodynamics Institute, Louisiana State University, Baton Rouge, LA 70803, USA
    Free Radic Biol Med 31:1132-8. 2001
    ..These reactive oxygen species generated by particles cause oxidative stress at sites of deposition and produce deleterious effects observed in the lung...
  7. ncbi request reprint Detection of aldehydes in bronchoalveolar lavage of rats exposed to ozone
    W A Pryor
    Biodynamics Institute, Louisiana State University, Baton Rouge 70803 1800, USA
    Fundam Appl Toxicol 34:148-56. 1996
    ....
  8. ncbi request reprint Scavenging of peroxynitrite by a phenolic/peroxidase system prevents oxidative damage to DNA
    S C Grace
    Biodynamics Institute, Louisiana State University, Baton Rouge 70803 1800, USA
    FEBS Lett 426:24-8. 1998
    ..9 is 3.4 x 10(7) M(-1) s(-1). This high rate suggests that CGA and other dietary polyphenols might efficiently scavenge peroxynitrite in peroxidase-containing systems in vivo...
  9. ncbi request reprint Overexpression of hMTH1 mRNA: a molecular marker of oxidative stress in lung cancer cells
    C H Kennedy
    Biodynamics Institute, Louisiana State University, Baton Rouge 70803, USA
    FEBS Lett 429:17-20. 1998
    ....
  10. ncbi request reprint Reaction of uric acid with peroxynitrite and implications for the mechanism of neuroprotection by uric acid
    G L Squadrito
    Biodynamics Institute, Louisiana State University, 711 Choppin Hall, Baton Rouge, Louisiana 70803 1800, USA
    Arch Biochem Biophys 376:333-7. 2000
    ..We suggest that trapping secondary radicals that result from the fast reaction of peroxynitrite with CO(2) may represent a new and viable approach for ameliorating the adverse effects associated with peroxynitrite in many diseases...
  11. ncbi request reprint Benzoyl peroxide interaction with mitochondria: inhibition of respiration and induction of rapid, large-amplitude swelling
    C H Kennedy
    Biodynamics Institute, Louisiana State University, Baton Rouge 70803
    Arch Biochem Biophys 271:456-70. 1989
    ..BPO-induced swelling appears to be disassociated from radical production and lipid peroxidation...
  12. ncbi request reprint Mapping the reaction of peroxynitrite with CO2: energetics, reactive species, and biological implications
    Giuseppe L Squadrito
    Biodynamics Institute, Louisiana State University, Baton Rouge, Louisiana 70803 1800, USA
    Chem Res Toxicol 15:885-95. 2002
  13. ncbi request reprint Synthesis of peroxynitrite in a two-phase system using isoamyl nitrite and hydrogen peroxide
    R M Uppu
    Biodynamics Institute, Louisiana State University, Baton Rouge 70803 1800, USA
    Anal Biochem 236:242-9. 1996
    ..7 % per day and should be used within 2-4 weeks. For short-term storage of about 1 week or less, these solutions can be stored at refrigerator temperatures (approximately 5 degrees C) where peroxynitrite has a half-life of about 7 days...
  14. doi request reprint Cholesterol secoaldehyde induces apoptosis in H9c2 cardiomyoblasts through reactive oxygen species involving mitochondrial and death receptor pathways
    K Sathishkumar
    Department of Environmental Toxicology and Health Research Center, Southern University and A and M College, Baton Rouge, LA 70813, USA
    Free Radic Biol Med 47:548-58. 2009
    ..This study clearly shows that ChSeco induces apoptosis in H9c2 cells through ROS generation and the activation of both the intrinsic and the extrinsic pathway...
  15. ncbi request reprint Activation and inactivation of cyclo-oxygenase in rat alveolar macrophages by aqueous cigarette tar extracts
    D Hwang
    Pennington Biomedical Research Center, Louisiana State University, Baton Rouge 70808, USA
    Free Radic Biol Med 27:673-82. 1999
    ..Increased PG production may lead to suppressed immune response and enhanced risk of tumorigenesis in smokers' lungs...
  16. ncbi request reprint The ozonation of cholesterol: separation and identification of 2,4-dinitrophenylhydrazine derivatization products of 3 beta-hydroxy-5-oxo-5,6-secocholestan-6-al
    K Wang
    Biodynamics Institute, Louisiana State University, Baton Rouge 70803 1800
    Steroids 58:225-9. 1993
    ..A possible mechanism involving an enamine functionality is proposed for the formation of 3a. The ratio of 3a/(3b + 3c) depends on the concentration of acid used and the reaction time...
  17. ncbi request reprint Causes and consequences of oxidative stress in Alzheimer's disease
    Mark A Smith
    Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA
    Free Radic Biol Med 32:1049. 2002
  18. ncbi request reprint Antioxidant-mediated augmentation of ozone-induced membrane oxidation
    Carol A Ballinger
    Department of Environmental Health Sciences, School of Public Health, RBPH 530, 1530 3rd Avenue South, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    Free Radic Biol Med 38:515-26. 2005
    ....
  19. ncbi request reprint The evolution of Free Radical Biology & Medicine: a 20-year history
    Kelvin J A Davies
    Free Radic Biol Med 39:1263-4. 2005