Daniel Keppler

Summary

Affiliation: Louisiana State University Health Sciences Center
Country: USA

Publications

  1. ncbi request reprint Towards novel anti-cancer strategies based on cystatin function
    Daniel Keppler
    Department of Cellular Biology and Anatomy and Feist Weiller Cancer Center, School of Medicine, Louisiana State University Health Sciences Center in Shreveport, 1501 Kings Highway, P O Box 33932, Shreveport, LA 71130, USA
    Cancer Lett 235:159-76. 2006
  2. ncbi request reprint Role of cystatins in tumor neovascularization
    Daniel Keppler
    Louisiana State University Health Sciences Center, Department of Cellular Biology and Anatomy and Feist Weiller Cancer Center, School of Medicine, Shreveport, LA 71130, USA
    Future Oncol 1:661-72. 2005
  3. ncbi request reprint The candidate tumor suppressor CST6 alters the gene expression profile of human breast carcinoma cells: down-regulation of the potent mitogenic, motogenic, and angiogenic factor autotaxin
    Jin Song
    Department of Cellular Biology and Anatomy, Louisiana State University Health Sciences Center, Shreveport, USA
    Biochem Biophys Res Commun 340:175-82. 2006
  4. ncbi request reprint Cystatin m: a novel candidate tumor suppressor gene for breast cancer
    Jun Zhang
    Department of Cellular Biology and Anatomy, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130 3932, USA
    Cancer Res 64:6957-64. 2004
  5. ncbi request reprint Cystatin M suppresses the malignant phenotype of human MDA-MB-435S cells
    Ravi Shridhar
    Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Oncogene 23:2206-15. 2004
  6. pmc Methylation-dependent silencing of CST6 in primary human breast tumors and metastatic lesions
    Ashley G Rivenbark
    Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Exp Mol Pathol 83:188-97. 2007
  7. pmc Inactivation of the cystatin E/M tumor suppressor gene in cervical cancer
    Mysore S Veena
    Department of Surgery, VAGLAHS David Geffen School of Medicine at UCLA, Los Angeles 90073, CA
    Genes Chromosomes Cancer 47:740-54. 2008

Collaborators

  • Timothy Clair
  • BONNIE F contact SLOANE
  • Benjamin D Li
  • G Sotiropoulou
  • Jin Song
  • Jun Zhang
  • Ravi Shridhar
  • Mysore S Veena
  • Ashley G Rivenbark
  • Lijia Yin
  • J Leslie Redpath
  • Eric J Stanbridge
  • Sharon P Wilczynski
  • Marc S Mendonca
  • Eri S Srivatsan
  • Grant Lee
  • Chad A Livasy
  • William B Coleman
  • Courtney E Boyd
  • Paula Polk
  • Chunfa Jie
  • Qun Dai
  • Carol Meschonat
  • Shayne C Barlow
  • Christopher G Kevil
  • Fleurette Abreo
  • Blake A Booth
  • Fred R Miller

Detail Information

Publications7

  1. ncbi request reprint Towards novel anti-cancer strategies based on cystatin function
    Daniel Keppler
    Department of Cellular Biology and Anatomy and Feist Weiller Cancer Center, School of Medicine, Louisiana State University Health Sciences Center in Shreveport, 1501 Kings Highway, P O Box 33932, Shreveport, LA 71130, USA
    Cancer Lett 235:159-76. 2006
    ..Based on the present understanding of cystatin function, novel avenues for anti-cancer strategies are proposed...
  2. ncbi request reprint Role of cystatins in tumor neovascularization
    Daniel Keppler
    Louisiana State University Health Sciences Center, Department of Cellular Biology and Anatomy and Feist Weiller Cancer Center, School of Medicine, Shreveport, LA 71130, USA
    Future Oncol 1:661-72. 2005
    ..Special emphasis is given to their potential role as novel anti-angiogenic agents...
  3. ncbi request reprint The candidate tumor suppressor CST6 alters the gene expression profile of human breast carcinoma cells: down-regulation of the potent mitogenic, motogenic, and angiogenic factor autotaxin
    Jin Song
    Department of Cellular Biology and Anatomy, Louisiana State University Health Sciences Center, Shreveport, USA
    Biochem Biophys Res Commun 340:175-82. 2006
    ..This study thus provides the first evidence that CST6 plays a role in the modulation of genes, particularly, genes that are highly relevant to breast cancer progression...
  4. ncbi request reprint Cystatin m: a novel candidate tumor suppressor gene for breast cancer
    Jun Zhang
    Department of Cellular Biology and Anatomy, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130 3932, USA
    Cancer Res 64:6957-64. 2004
    ..Immunohistochemical studies confirmed that expression of cystatin M in IDCs was partially or completely lost. We propose cystatin M as a novel candidate tumor suppressor gene for breast cancer...
  5. ncbi request reprint Cystatin M suppresses the malignant phenotype of human MDA-MB-435S cells
    Ravi Shridhar
    Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Oncogene 23:2206-15. 2004
    ..This study provides the first evidence that cystatin M may play important roles in safeguarding against human breast cancer...
  6. pmc Methylation-dependent silencing of CST6 in primary human breast tumors and metastatic lesions
    Ashley G Rivenbark
    Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Exp Mol Pathol 83:188-97. 2007
    ..Overall, the results of the current investigation suggest that methylation-dependent epigenetic silencing of CST6 represents an important mechanism for loss of CST6 during breast tumorigenesis and/or progression to metastasis...
  7. pmc Inactivation of the cystatin E/M tumor suppressor gene in cervical cancer
    Mysore S Veena
    Department of Surgery, VAGLAHS David Geffen School of Medicine at UCLA, Los Angeles 90073, CA
    Genes Chromosomes Cancer 47:740-54. 2008
    ..We conclude, therefore, that cystatin E/M is a cervical cancer suppressor gene and that the gene is inactivated by somatic mutations and promoter hypermethylation...