Bryan M Gebhardt

Summary

Affiliation: Louisiana State University Health Sciences Center
Country: USA

Publications

  1. ncbi request reprint Experimental corneal allograft rejection
    Bryan M Gebhardt
    Lions Eye Research Laboratories, LSU Eye Center, LSU Health Sciences Center, New Orleans, LA 70112 2234, USA
    Immunol Res 25:1-26. 2002
  2. pmc Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1
    William P Halford
    Dept of Veterinary Molecular Biology, Montana State University, Bozeman, MT, USA
    Virol J 2:56. 2005
  3. pmc ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency
    William P Halford
    Dept of Veterinary Molecular Biology, Montana State University, Bozeman, MT, USA
    Virol J 3:44. 2006
  4. pmc Evidence that spontaneous reactivation of herpes virus does not occur in mice
    Bryan M Gebhardt
    LSU Eye Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Virol J 2:67. 2005
  5. ncbi request reprint Inhibition of cyclooxygenase 2 synthesis suppresses Herpes simplex virus type 1 reactivation
    Bryan M Gebhardt
    Lions Eye Research Laboratories, LSU Eye Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112 2234, USA
    J Ocul Pharmacol Ther 21:114-20. 2005
  6. ncbi request reprint Acetylsalicylic acid reduces viral shedding induced by thermal stress
    Bryan M Gebhardt
    Lions Eye Research Laboratories, LSU Eye Center, Louisiana State University Health Sciences Center, 2020 Gravier Street, New Orleans, LA 70112 2234, USA
    Curr Eye Res 29:119-25. 2004
  7. ncbi request reprint Effect of acyclovir on thermal stress-induced herpesvirus reactivation
    Bryan M Gebhardt
    Lions Eye Research Laboratories, LSU Eye Center, Louisiana State University Health Sciences Center, 2020 Gravier Street, New Orleans, LA 70112 2234, USA
    Curr Eye Res 29:137-44. 2004
  8. pmc Efficacy of a helicase-primase inhibitor in animal models of ocular herpes simplex virus type 1 infection
    Herbert E Kaufman
    Department of Ophthalmology, LSU Eye Center, Louisiana State University Health Sciences Center in New Orleans, New Orleans, LA, USA
    J Ocul Pharmacol Ther 24:34-42. 2008
  9. pmc Blockade of the 4-1BB (CD137)/4-1BBL and/or CD28/CD80/CD86 costimulatory pathways promotes corneal allograft survival in mice
    Tatsuhiko Asai
    LSU Eye Center, LSU Health Sciences Center School of Medicine, New Orleans, LA, USA
    Immunology 121:349-58. 2007
  10. pmc Re-evaluating natural resistance to herpes simplex virus type 1
    William P Halford
    Department of Microbiology and Immunology, Tulane University Medical School, New Orleans, LA, USA
    J Virol 78:10086-95. 2004

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Experimental corneal allograft rejection
    Bryan M Gebhardt
    Lions Eye Research Laboratories, LSU Eye Center, LSU Health Sciences Center, New Orleans, LA 70112 2234, USA
    Immunol Res 25:1-26. 2002
    ..Combinations of antiangiogenic agents and immunomodulators hold great promise for preventing corneal allograft rejection in patients...
  2. pmc Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1
    William P Halford
    Dept of Veterinary Molecular Biology, Montana State University, Bozeman, MT, USA
    Virol J 2:56. 2005
    ..The current study was initiated to determine if natural killer (NK) cells provide innate resistance to HSV-1 infection, and if so to determine if this resistance is IFN-gamma-dependent...
  3. pmc ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency
    William P Halford
    Dept of Veterinary Molecular Biology, Montana State University, Bozeman, MT, USA
    Virol J 3:44. 2006
    ....
  4. pmc Evidence that spontaneous reactivation of herpes virus does not occur in mice
    Bryan M Gebhardt
    LSU Eye Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Virol J 2:67. 2005
    ..The goal of this study was to differentiate between viral gene expression during latency and the episodic production of infectious virus in mice...
  5. ncbi request reprint Inhibition of cyclooxygenase 2 synthesis suppresses Herpes simplex virus type 1 reactivation
    Bryan M Gebhardt
    Lions Eye Research Laboratories, LSU Eye Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112 2234, USA
    J Ocul Pharmacol Ther 21:114-20. 2005
    ..It may be possible to use COX-2 inhibitors to prevent viral reactivation in high-risk patients by drug prophylaxis...
  6. ncbi request reprint Acetylsalicylic acid reduces viral shedding induced by thermal stress
    Bryan M Gebhardt
    Lions Eye Research Laboratories, LSU Eye Center, Louisiana State University Health Sciences Center, 2020 Gravier Street, New Orleans, LA 70112 2234, USA
    Curr Eye Res 29:119-25. 2004
    ..To investigate the effect of acetylsalicylic acid on ocular shedding of herpes simplex virus type 1 (HSV-1)...
  7. ncbi request reprint Effect of acyclovir on thermal stress-induced herpesvirus reactivation
    Bryan M Gebhardt
    Lions Eye Research Laboratories, LSU Eye Center, Louisiana State University Health Sciences Center, 2020 Gravier Street, New Orleans, LA 70112 2234, USA
    Curr Eye Res 29:137-44. 2004
    ..The purpose of the current study was to determine the effect of acyclovir on the appearance of infectious virus in the peripheral nervous system and in an end organ, the eye...
  8. pmc Efficacy of a helicase-primase inhibitor in animal models of ocular herpes simplex virus type 1 infection
    Herbert E Kaufman
    Department of Ophthalmology, LSU Eye Center, Louisiana State University Health Sciences Center in New Orleans, New Orleans, LA, USA
    J Ocul Pharmacol Ther 24:34-42. 2008
    ..The aim of this study was to evaluate the effect of BAY 57-1293, a helicase-primase inhibitor, on herpes simplex virus type 1 (HSV-1) reactivation in mice and its efficacy on established disease in rabbits...
  9. pmc Blockade of the 4-1BB (CD137)/4-1BBL and/or CD28/CD80/CD86 costimulatory pathways promotes corneal allograft survival in mice
    Tatsuhiko Asai
    LSU Eye Center, LSU Health Sciences Center School of Medicine, New Orleans, LA, USA
    Immunology 121:349-58. 2007
    ....
  10. pmc Re-evaluating natural resistance to herpes simplex virus type 1
    William P Halford
    Department of Microbiology and Immunology, Tulane University Medical School, New Orleans, LA, USA
    J Virol 78:10086-95. 2004
    ....
  11. ncbi request reprint Effect of immunosuppression on gene expression in the HSV-1 latently infected mouse trigeminal ganglion
    Shiro Higaki
    Department of Ophthalmology, LSU Eye Center, New Orleans, Louisiana 70112, USA
    Invest Ophthalmol Vis Sci 43:1862-9. 2002
    ..To determine alterations in expression of genes in herpes simples virus (HSV)-1 latently infected mouse trigeminal ganglia (TGs), after treatment with cyclophosphamide and dexamethasone...
  12. ncbi request reprint CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses
    Dass S Vinay
    Louisiana State University Eye Center, Louisiana State University Health Sciences Center School of Medicine, New Orleans, LA 70112, USA
    J Immunol 173:4218-29. 2004
    ....
  13. ncbi request reprint Corneal epithelial cell growth over tethered-protein/peptide surface-modified hydrogels
    Jean T Jacob
    LSU Eye Center, LSU Health Sciences Center, 2020 Gravier Street, Suite B, New Orleans, Louisiana 70112, USA
    J Biomed Mater Res B Appl Biomater 72:198-205. 2005
    ....
  14. ncbi request reprint Distribution of thrombospondin-4 in the bovine eye
    Zhaomin Si
    LSU Eye Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Curr Eye Res 27:165-73. 2003
    ..The purpose of this study was to analyze the distribution of thrombospondin-4 (TSP-4) in the bovine eye...
  15. pmc Inhibition of herpes simplex virus thymidine kinases by 2-phenylamino-6-oxopurines and related compounds: structure-activity relationships and antiherpetic activity in vivo
    Andrzej Manikowski
    GLSynthesis Inc, One Innovation Drive, Worcester, Massachusetts 01605, USA
    J Med Chem 48:3919-29. 2005
    ..In assays lacking [3H]thymidine, HBPG was found to be an efficient substrate for the enzymes. The ability of the TKs to phosphorylate HBPG may relate to its antiherpetic activity in vivo...
  16. ncbi request reprint Herpesvirus infection of ICAM-1-deficient mice
    Hyo W Jung
    Immunomodulation Research Center, University of Ulsan, 29 Mukeo dong, Nam Ku, Ulsan, Korea 680 749
    Curr Eye Res 29:201-8. 2004
    ..To determine the effect of ICAM-1 deficiency on viral infection of the cornea...